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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RADIL Gene

protein-coding GIFtS: 52
GCID: GC07M004836

Ras association and DIL domains

Explore 3 diseases affiliated with
RADIL via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ras Association And DIL Domains¹ ²
KIAA1849¹ ³ ⁵
RASIP2¹ ²
FLJ10324¹
Rap GTPase Interactor²
Ras-Associating And Dilute Domain-Containing Protein²

External Ids:	HGNC: 22226¹	Entrez Gene: 55698²	Ensembl: ENSG00000157927⁷	OMIM: 611491⁵	UniProtKB: Q96JH8³

Export aliases for RADIL gene to outside databases

Previous GC identifers: GC07M004804 GC07M004755

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RADIL_HUMAN, Q96JH8

Function: Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during

development

Gene Wiki entry for RADIL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RADIL gene promoter:
Sp1 MAZR AP-1 ATF-2 MyoD MIF-1 CUTL1 C/EBPalpha c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RADIL promoter sequence

Search SABiosciences Chromatin IP Primers for RADIL

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RADIL

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.1 Ensembl cytogenetic band: 7p22.1 HGNC cytogenetic band: 7p22.1

RADIL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RADIL gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M004836: view genomic region (about GC identifiers)

Start:	4,836,686 bp from pter	End:	4,923,350 bp from pter
Size:	86,665 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 4,885,095-4,969,690

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RADIL_HUMAN, Q96JH8 (See protein sequence)

Recommended Name: Ras-associating and dilute domain-containing protein

Size: 1075 amino acids; 117455 Da

Subunit: Interacts with RAP1A; in a GTP-dependent manner. Does not interact with members of the Ras family

Sequence caution: Sequence=AAS07559.1; Type=Erroneous gene model prediction; Sequence=BAA91543.1; Type=Erroneous

initiation; Note=Translation N-terminally extended; Sequence=BAB47478.1; Type=Erroneous initiation; Note=Translation

N-terminally shortened;

2 PDB 3D structures from and Proteopedia for RADIL:

1UM1 (3D)

3EC8 (3D)

Secondary accessions: A4D1Z5 A5YM49 B7ZL20 Q0VFZ9 Q75LH3 Q9BSP5 Q9H0M6 Q9NW43 Q9NWC4

Alternative splicing: 4 isoforms: Q96JH8-4 Q96JH8-2 Q96JH8-3 Q96JH8-1 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RADIL: NX_Q96JH8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96JH8

RADIL Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_060529.4

ENSEMBL proteins:

ENSP00000413403 ENSP00000382492 ENSP00000398057 ENSP00000442966 ENSP00000442533

Human Recombinant Protein Products for RADIL:

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	Novus Biologicals RADIL Protein
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	Uscn Proteins for RADIL

RADIL Antibody Products:

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	Novus Biologicals RADIL Antibody
	Abcam antibodies for RADIL
	Uscn Antibodies for RADIL
	ThermoFisher Antibody for RADIL

Assay Products for RADIL:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RADIL
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RADIL

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RADIL for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR008984 SMAD_FHA_domain

IPR018444 Dil_domain

IPR002710 Dilute

IPR000159 Ras-assoc

IPR001478 PDZ

Graphical View of Domain Structure for InterPro Entry Q96JH8

ProtoNet protein and cluster: Q96JH8

3 Blocks protein families:

IPB000159 RA domain

IPB000253 Forkhead-associated (FHA)

IPB001478 PDZ/DHR/GLGF domain

UniProtKB/Swiss-Prot: RADIL_HUMAN, Q96JH8

Similarity: Belongs to the RADIL family

Similarity: Contains 1 dilute domain

Similarity: Contains 1 FHA domain

Similarity: Contains 1 PDZ (DHR) domain

Similarity: Contains 1 Ras-associating domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: RADIL_HUMAN, Q96JH8

Function: Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during

development

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RADIL

miRNA Products:		OriGene 3'-UTR Clone: RADIL Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RADIL
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate RADIL:
		hsa-miR-136 hsa-miR-495
		SwitchGear 3'UTR luciferase reporter plasmid: RADIL 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RADIL (see all 4) OriGene shRNA RFP: RADIL OriGene siRNA: RADIL
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RADIL
		Sirion Biotech Custom design and validation of potent shRNA sequences against RADIL

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for RADIL
			Sirion Biotech Customized adenovirus for overexpression of RADIL Sirion Biotech Customized adenovirus for potent knockdown of RADIL

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RADIL (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RADIL (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RADIL (NM_018059)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RADIL
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RADIL

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RADIL
		Search LifeMap BioReagents cell lines for RADIL
		Sirion Biotech Customized stable knockdown cell line services for RADIL Sirion Biotech Customized inducible knockdown cell line services for RADIL Sirion Biotech Customized stable overexpressing cell line services for RADIL Sirion Biotech Customized inducible overexpressing cell line services for RADIL

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RADIL

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RADIL

STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

5/27 Interacting proteins for RADIL (Q96JH8^{1, 2, 3} ENSP00000382492⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 27)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RHOXF2	Q9BQY4²^,³, ENSP00000360441⁴	MINT-66865 I2D: score=5 STRING: ENSP00000360441
MED19	A0JLT2²^,³, ENSP00000337340⁴	STRING: ENSP00000337340 MINT-64897 I2D: score=4
CDK2	P24941¹^,³, ENSP00000266970⁴	EBI-744267,EBI-375096 I2D: score=2 STRING: ENSP00000266970
ASCC2	Q9H1I8²^,³	MINT-65473 I2D: score=4
LITAF	Q99732²^,³	MINT-65289 I2D: score=3

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007155	cell adhesion	IEA	--
GO:0007165	signal transduction	IEA	--
GO:0007275	multicellular organismal development	IEA	--

RADIL for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RADIL
Search CenterWatch for drugs/clinical trials and news about RADIL

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RADIL gene:

NM_018059.4

Unigene Cluster for RADIL:

Ras association and DIL domains

Hs.667336 [show with all ESTs]

Unigene Representative Sequence: NM_018059

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000445392(uc003sng.1 uc003snh.1 uc003sni.1 uc011jwc.1 uc003snj.1 uc011jwd.1)

ENST00000472999 ENST00000399583 ENST00000473130 ENST00000469399 ENST00000484211

ENST00000457174 ENST00000538469 ENST00000536091

miRNA Products:		OriGene 3'-UTR Clone: RADIL Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RADIL
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate RADIL:
		hsa-miR-136 hsa-miR-495
		SwitchGear 3'UTR luciferase reporter plasmid: RADIL 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RADIL (see all 4) OriGene shRNA RFP: RADIL OriGene siRNA: RADIL
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RADIL
		Sirion Biotech Custom design and validation of potent shRNA sequences against RADIL

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RADIL (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RADIL (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RADIL (NM_018059)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RADIL
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RADIL

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RADIL Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RADIL
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RADIL
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RADIL

Additional cDNA sequence:

AK000997.1 AK001186.1 AK294745.1 AK296325.1 AK302549.1 AL136731.1 BC004919.2 BC117317.1

BC126311.1 BC143526.1 EF560723.1

10 DOTS entries:

DT.75121763 DT.121038453 DT.91744549 DT.65286966 DT.97802978 DT.97838575 DT.121038444 DT.91966600

DT.95095224 DT.316476

24/72 AceView cDNA sequences (see all 72):

AK000997 BF114928 AB058752 BM799509 BQ070639 AL044980 CR598494 NM_018059

AI076876 AK001186 AW296772 BM725350 BE730297 BQ232134 BE885462 BE276824

AI041242 BX431000 AU118216 BI117602 BQ889832 BU687528 AU123576 BE728814

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RADIL (see all 10) About this scheme

ExUns:	1	^	2a	·	2b	·	2c	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	^	13	^	14a	·	14b	·	14c	^	15	^	16	^
SP1:
SP2:
SP3:																																							-
SP4:																																							-
SP5:

ExUns:	17
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for RADIL

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RADIL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CATCTCAGTG

About this image

RADIL expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Outer Nuclear Layer

Mature Rod Cells

Photoreceptors, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

See RADIL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RADIL

SOURCE GeneReport for Unigene cluster: Hs.667336

SABiosciences Custom PCR Arrays for RADIL

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RADIL Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RADIL
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RADIL

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RADIL

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RADIL gene from 4/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	RADIL¹	Ras association and DIL domains	71.38(n) 65.9(a)		416479 XM_003642143.1 XP_003642191.1
lizard (Anolis carolinensis)	Reptilia	RADIL⁶	--	58(a)	1 ↔ 1	GL343591.1(180354-225767)
zebrafish (Danio rerio)	Actinopterygii	radil¹	Rap GTPase interactor	58.14(n) 53.93(a)		562363 NM_001102569.1 NP_001096039.1
rice (Oryza sativa)	Liliopsida	AK068880.1²	--	73.37(n)		AK068880.1

ENSEMBL Gene Tree for RADIL (if available)
TreeFam Gene Tree for RADIL (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RADIL gene

RASIP1²

5 SIMAP similar genes for RADIL using alignment to 5 protein entries: RADIL_HUMAN (see all proteins):

FLJ10324 DLG4 RASIP1 TJP2 FRMPD2

RADIL for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs79959107^1,2		--	4838301(+)	`GGGCCG/ACCAGC`	1	--	int¹		3		CSA WA NA	240
rs78479125^1,2	F	--	4838347(+)	`GAGAGG/TAACTC`	1	--	int¹		1		NA	120
rs73307312^1,2	C	--	4838365(+)	`AGCAGG/TAGTCC`	1	--	int¹		2		WA	120
rs77872900^1,2	C,F	--	4838381(+)	`GAGGAA/GGCAGG`	1	--	int¹		5		WA CSA NA EA	362
rs117582994^1,2	F	--	4838419(+)	`ACCATC/GAGGCC`	1	--	int¹		1		EA	120
rs77769319^1,2	C,F	--	4838438(+)	`TTCCAA/GCGCCT`	1	--	int¹		1		EA	120
rs73307313^1,2	C	--	4838440(+)	`CCAACG/ACCTGG`	1	--	int¹		2		WA	120
rs145254284^1,2		--	4838454(+)	`TCTAGA/CCCTTT`	1	--	int¹		0	--	--	--	--
rs73307314^1,2	C	--	4838476(+)	`GTGCTG/AAGCAG`	1	--	int¹		3		WA NA	240
rs73307315^1,2	C	--	4838582(+)	`GGGACG/AGGGGC`	1	--	int¹		2		WA	120

HapMap Linkage Disequilibrium report for RADIL (4836686 - 4923350 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RADIL
2 CNVs: 32863 69784

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RADIL

DNA2.0 Custom Variant and Variant Library Synthesis for RADIL

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RADIL for disorders           About GeneDecksing

OMIM gene information: 611491    OMIM disorders: --

3 diseases for RADIL:    About MalaCards

keratoconus myopia ataxia

1 disease from the University of Copenhagen DISEASES database for RADIL:

Keratoconus

Export disorders for RADIL gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RADIL gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with RADIL)

Utopia: connect your pdf to the dynamic
world of online information

A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors. (PubMed id 17704304)^{1, 2, 3} Smolen G.A.... Haber D.A. (2007)
AF6 negatively regulates Rap1-induced cell adhesion. (PubMed id 16051602)^{1, 3} Zhang Z....Bos J.L. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)^{1, 2} Nagase T.... Ohara O. (2001)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
KIF14 negatively regulates Rap1a-Radil signaling durin g breast cancer progression. (PubMed id 23209302)¹ Ahmed S.M....Angers S. (2012)
G protein betagamma subunits regulate cell adhesion t hrough Rap1a and its effector Radil. (PubMed id 20048162)¹ Ahmed S.M....Angers S. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 55698	HGNC: 22226	AceView: FLJ10324	Ensembl:ENSG00000157927	euGenes: HUgn55698
ECgene: RADIL	H-InvDB: RADIL

(According to HUGE)
About This Section

HUGE: KIAA1849

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RADIL	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RADIL gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for RADIL gene:
Search GeneIP for patents involving RADIL

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RADIL
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RADIL
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Search for Antibodies & Assays

	Regulatory tfbs in RADIL promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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RADIL Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RADIL

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RADIL

	SwitchGear 3'UTR luciferase reporter plasmids for RADIL
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ThermoFisher Antibody for RADIL

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RADIL

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RADIL

Sirion Biotech Customized:

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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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RADIL Gene

Ras association and DIL domains

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RADIL Gene

Ras association and DIL domains

Aliasesfor RADIL gene

Summariesfor RADIL gene

Genomic Viewsfor RADIL gene

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Functionfor RADIL gene

Pathways & Interactionsfor RADIL gene

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Expression for RADIL gene

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External Searches for RADIL gene

Genome Databases showing RADIL gene

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Specialized Databases showing RADIL gene

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for RADIL gene

Genomic Views
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for RADIL gene

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for RADIL gene

Transcripts
for RADIL gene

Expression
for RADIL gene

Orthologs
for RADIL gene

Paralogs
for RADIL gene

Genomic Variants
for RADIL gene

Disorders / Diseases
for RADIL gene

Publications
for RADIL gene

Intellectual Property
for RADIL gene

Products
for RADIL gene