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RAD9B Gene

protein-coding   GIFtS: 50
GCID: GC12P110939

RAD9 Homolog B (S. Pombe)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAD9 Homolog B (S. Pombe)1 2
DNA Repair Exonuclease Rad9 Homolog B2 3
Cell Cycle Checkpoint Control Protein RAD9B2
hRAD9B3

External Ids:    HGNC: 217001   Entrez Gene: 1447152   Ensembl: ENSG000001511647   OMIM: 6083685   UniProtKB: Q6WBX83   

Export aliases for RAD9B gene to outside databases

Previous GC identifers: GC12P110782 GC12P109351 GC12P109402 GC12P107958


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAD9B Gene:
RAD9B (RAD9 homolog B (S. pombe)) is a protein-coding gene. An important paralog of this gene is RAD9A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAD9B gene promoter:
         GR   Pax-2   HSF1 (long)   Pax-2a   C/EBPalpha   Evi-1   Egr-2   S8   HSF1short   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAD9B promoter sequence
   Search Chromatin IP Primers for RAD9B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAD9B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.11   Ensembl cytogenetic band:  12q24.11   HGNC cytogenetic band: 12q24.13

RAD9B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAD9B gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P110939:  view genomic region     (about GC identifiers)

Start:
110,939,460 bp from pter      End:
110,969,891 bp from pter
Size:
30,432 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RAD9B_HUMAN, Q6WBX8 (See protein sequence)
Recommended Name: Cell cycle checkpoint control protein RAD9B  
Size: 426 amino acids; 47832 Da
Subunit: Interacts with HUS1, HUS1B, RAD1, RAD9A and RAD17
Secondary accessions: Q5U5K0 Q6NVJ1 Q6ZVT7 Q8N7T9 Q96LI8
Alternative splicing: 5 isoforms:  Q6WBX8-5   Q6WBX8-1   Q6WBX8-2   Q6WBX8-3   Q6WBX8-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAD9B: NX_Q6WBX8

Explore proteomics data for RAD9B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAD9B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001273460.1  NP_001273461.1  NP_001273462.1  NP_001273463.1  NP_001273464.1  NP_001273465.1  NP_689655.3  

    ENSEMBL proteins: 
     ENSP00000387329   ENSP00000376440   ENSP00000386434   ENSP00000386629   ENSP00000386697  
     ENSP00000350777  
    Reactome Protein details: Q6WBX8

    RAD9B Human Recombinant Protein Products:

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    Novus Biologicals RAD9B Proteins
    Novus Biologicals RAD9B Lysate
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RAD9B

     
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    antibodies-online proteins for RAD9B (7 products) 

     
    Search antibodies-online for peptides for RAD9B

    RAD9B Antibody Products:

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    Abcam antibodies for RAD9B
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    antibodies-online antibodies for RAD9B (6 products) 

    RAD9B Assay Products:

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    Cloud-Clone Corp. ELISAs for RAD9B
    Cloud-Clone Corp. CLIAs for RAD9B
    Search eBioscience for ELISAs for RAD9B 
    antibodies-online kits for RAD9B (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR026584 Rad9
     IPR007268 Rad9/Ddc1

    Graphical View of Domain Structure for InterPro Entry Q6WBX8

    ProtoNet protein and cluster: Q6WBX8

    UniProtKB/Swiss-Prot: RAD9B_HUMAN, Q6WBX8
    Similarity: Belongs to the rad9 family


    Find genes that share domains with RAD9B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI14500360
         
    Find genes that share ontologies with RAD9B           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RAD9B:
     Decreased POU5F1-GFP protein e  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rad9b):
     cellular  embryogenesis  growth/size/body  mortality/aging  nervous system 

    Find genes that share phenotypes with RAD9B           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Rad9btm1Lieb for RAD9B

       genOway: Develop your customized and physiologically relevant rodent model for RAD9B

    miRNA
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    Block miRNA regulation of human, mouse, rat RAD9B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAD9B (see all 9):
    hsa-miR-30c hsa-miR-3132 hsa-miR-154 hsa-miR-30d hsa-miR-29b-1* hsa-miR-30a hsa-miR-30b hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidRAD9B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RAD9B
    Predesigned siRNA for gene silencing in human, mouse, rat RAD9B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RAD9B

    Clone
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    OriGene ORF clones in mouse, rat for RAD9B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAD9B (NM_152442)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAD9B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD9B

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for RAD9B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD9B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol1
    extracellular1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0030896checkpoint clamp complex IEA--

    Find genes that share ontologies with RAD9B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAD9B About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1G2/M Checkpoints
    G2/M Checkpoints0.84
    Activation of ATR in response to replication stress0.84
    2Cell Cycle, Mitotic
    Cell Cycle0.90
    3CDK-mediated phosphorylation and removal of Cdc6
    Cell Cycle Checkpoints0.58
    4Transcription Androgen Receptor nuclear signaling
    Transcription Androgen Receptor nuclear signaling0.49
    5Meiosis (EMD)
    Meiosis


    Find genes that share SuperPaths with RAD9B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for RAD9B
        Transcription Androgen Receptor nuclear signaling
    DNA damage ATM/ATR regulation of G1/S checkpoint

    1 Reactome Pathway for RAD9B
        Activation of ATR in response to replication stress


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAD9B
    Interactions:

        GeneGlobe Interaction Network for RAD9B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAD9B (Q6WBX83 ENSP000003764404) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HUS1O609213, ENSP000002587744I2D: score=2 STRING: ENSP00000258774
    HUS1BQ8NHY53, ENSP000003702934I2D: score=2 STRING: ENSP00000370293
    RAD1O606713, ENSP000003408794I2D: score=1 STRING: ENSP00000340879
    RAD9AQ996383, ENSP000003113604I2D: score=1 STRING: ENSP00000311360
    RAD17O759433, ENSP000003701514I2D: score=2 STRING: ENSP00000370151
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000075cell cycle checkpoint ----
    GO:0000077DNA damage checkpoint IEA--
    GO:0006260DNA replication TAS--
    GO:0006281DNA repair IEA--

    Find genes that share ontologies with RAD9B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAD9B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAD9B gene (7 alternative transcripts): 
    NM_001286531.1  NM_001286532.1  NM_001286533.1  NM_001286534.1  NM_001286535.1  NM_001286536.1  NM_152442.3  

    Unigene Cluster for RAD9B:

    RAD9 homolog B (S. pombe)
    Hs.97794  [show with all ESTs]
    Unigene Representative Sequence: BC047645
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000433301 ENST00000409246(uc001trf.4 uc001trg.4 uc010sya.2)
    ENST00000392672 ENST00000409300 ENST00000409425(uc001tre.4) ENST00000409778
    ENST00000409461 ENST00000358071(uc001trd.4) ENST00000447044
    miRNA
    Products:
         
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    Selected qRT-PCR Assays for microRNAs that regulate RAD9B (see all 9):
    hsa-miR-30c hsa-miR-3132 hsa-miR-154 hsa-miR-30d hsa-miR-29b-1* hsa-miR-30a hsa-miR-30b hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidRAD9B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RAD9B
    Predesigned siRNA for gene silencing in human, mouse, rat RAD9B
    Clone
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    OriGene clones in human, mouse for RAD9B (see all 6)
    OriGene ORF clones in mouse, rat for RAD9B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAD9B (NM_152442)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAD9B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD9B
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAD9B
      QuantiTect SYBR Green Assays in human, mouse, rat RAD9B
      QuantiFast Probe-based Assays in human, mouse, rat RAD9B

    Additional mRNA sequence: 

    AK056139.1 AK058176.1 AK097665.1 AK124109.1 AK301826.1 AK302512.1 AY297459.1 BC037353.1 
    BC047645.1 BC064974.1 BC068031.1 

    10 DOTS entries:

    DT.97774636  DT.99998055  DT.100685960  DT.91830394  DT.205415  DT.436246  DT.97778071  DT.121216149 
    DT.97792540  DT.99945339 

    24 AceView cDNA sequences:

    AK097665 BX280464 NM_152442 BX094118 AK124109 AA412179 AK056139 CB127251 
    AY297459 BC068031 BC047645 BG718006 AA970946 CD511820 BC037353 AA399017 
    BI459646 BP371414 CD244296 BC064974 AK058176 BU193721 AA400412 AA400411 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RAD9B    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13
    SP1:              -                       -                                                     -         
    SP2:                                                                                                      
    SP3:                                                                                                      


    ECgene alternative splicing isoforms for RAD9B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAD9B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTTTTTTG
    RAD9B Expression
    About this image

    RAD9B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAD9B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.97794

    UniProtKB/Swiss-Prot: RAD9B_HUMAN, Q6WBX8
    Tissue specificity: Expressed in testis and skeletal muscle

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAD9B gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rad9b1 , 5 RAD9 homolog B (S. cerevisiae)5
    RAD9 homolog B1
    74.4(n)1
    64.84(a)1
      5 (62.30 cM)5
    2317241  NM_144912.31  NP_659161.21 
     1223232235 
    chicken
    (Gallus gallus)
    Aves RAD9B1 RAD9 homolog B (S. pombe) 60(n)
    47.34(a)
      416868  XM_415160.4  XP_415160.4 
    lizard
    (Anolis carolinensis)
    Reptilia RAD9B6
    RAD9 homolog B (S. pombe)
    41(a)
    1 ↔ 1
    GL343423.1(318089-330455)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rad9b1 RAD9 homolog B (S. pombe) 57.21(n)
    44.18(a)
      100490318  XM_002937697.2  XP_002937743.2 
    zebrafish
    (Danio rerio)
    Actinopterygii rad9a1 RAD9 homolog A 55.75(n)
    42.86(a)
      563903  XM_687266.4  XP_692358.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rad96
    Rad9
    16(a)
    1 → many
    3L(18863145-18865653)
    worm
    (Caenorhabditis elegans)
    Secernentea hpr-96
    Protein HPR-9 (hpr-9) mRNA, complete cds
    16(a)
    1 → many
    III(10621541-10626383) WBGene00001997


    ENSEMBL Gene Tree for RAD9B (if available)
    TreeFam Gene Tree for RAD9B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAD9B gene
    RAD9A2  
    1 SIMAP similar gene for RAD9B using alignment to 5 protein entries:     RAD9B_HUMAN (see all proteins):
    RAD9A

    Find genes that share paralogs with RAD9B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAD9B (see all 517)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1452322131,2
    --110941995(+) GAGGCC/TGGGCG 1 -- int10--------
    rs1381373081,2
    C--110942051(+) GGTGGA/GTCACC 1 -- int10--------
    rs731918251,2
    C,F--110942205(+) GCAGAT/CGGAGG 1 -- int14Minor allele frequency- C:0.09WA CSA NA 242
    rs110656521,2
    C,F,H--110942340(+) ATTCAG/AAAGAC 1 -- int111Minor allele frequency- A:0.01NS EA NA 1380
    rs1841206101,2
    --110942414(+) TTCCCC/TGCTTA 1 -- int10--------
    rs1888651521,2
    --110942435(+) GAGACC/TGCCAA 1 -- int10--------
    rs1816147341,2
    --110942605(+) GAGACC/TAGCCT 1 -- int10--------
    rs783577881,2
    --110942672(+) GTGATA/GTGTTG 1 -- int10--------
    rs744303511,2
    C,F--110942677(+) ATGTTG/ATGTGC 1 -- int11Minor allele frequency- A:0.09WA 118
    rs1431394091,2
    --110942831(+) TTAAAA/CGAAAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for RAD9B (110939460 - 110969891 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RAD9B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746355CNV Deletion23290073
    esv1243811CNV Deletion17803354
    nsv507675CNV Insertion20534489
    nsv826512CNV Loss20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAD9B
    DNA2.0 Custom Variant and Variant Library Synthesis for RAD9B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608368    OMIM disorders: --


    Find genes that share disorders with RAD9B           About GenesLikeMe


    Export disorders for RAD9B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAD9B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RAD9B)
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    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Identification and characterization of RAD9B, a paralog of the RAD9 checkpoint gene. (PubMed id 14611806)1, 2 Dufault V.M.... Karnitz L.M. (Genomics 2003)
    4. Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue. (PubMed id 14500360)1, 2 Hopkins K.M....Lieberman H.B. (Cancer Res. 2003)
    5. Rad9B responds to nucleolar stress through ATR and JNK signalling, and delays the G1-S transition. (PubMed id 22399810)1 PAcrez-Castro A.J. and Freire R. (J. Cell. Sci. 2012)
    6. Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. (PubMed id 16365875)1 Lieberman H.B. (J. Cell. Biochem. 2006)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    9. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. (PubMed id 12791985)1 Zou L. and Elledge S.J. (Science 2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 144715 HGNC: 21700 AceView: RAD9B Ensembl:ENSG00000151164 euGenes: HUgn144715
    ECgene: RAD9B H-InvDB: RAD9B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAD9B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAD9B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAD9B gene:
    Search GeneIP for patents involving RAD9B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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