Aliases for RAD54L Gene
Aliases for RAD54L Gene
External Ids for RAD54L Gene
- HGNC: 9826
- Entrez Gene: 8438
- Ensembl: ENSG00000085999
- OMIM: 603615
- UniProtKB: Q92698
Previous GeneCards Identifiers for RAD54L Gene
- GC01P046407
- GC01P045670
- GC01P046099
- GC01P046083
- GC01P046425
- GC01P046485
- GC01P046713
- GC01P044829
Summaries for RAD54L Gene
-
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]
GeneCards Summary for RAD54L Gene
RAD54L (RAD54 Like (S. Cerevisiae)) is a Protein Coding gene. Diseases associated with RAD54L include Lymphoma, Non-Hodgkin and Breast Cancer. Among its related pathways are Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) and Integrated Breast Cancer Pathway. GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is ATRX.
UniProtKB/Swiss-Prot for RAD54L Gene
-
Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAD54L Gene
Genomics for RAD54L Gene
Regulatory Elements for RAD54L Gene
Enhancers for RAD54L Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G046196 | 1.3 | ENCODE dbSUPER | 11.2 | -49.4 | -49443 | 2.8 | HDGF ARNT SIN3A DMAP1 ZNF48 TCF12 ELK1 ZNF143 KLF13 ZNF263 | LURAP1 POMGNT1 PIK3R3 TSPAN1 ENSG00000250719 RAD54L TOE1 |
| GH01G046202 | 1.1 | ENCODE | 11.8 | -43.0 | -42950 | 4.4 | HDGF CREB3L1 ARNT SIN3A ZNF2 YY1 ZNF143 ZNF207 KLF13 ZNF263 | LURAP1 NSUN4 RAD54L ENSG00000250719 PIK3R3 TSPAN1 POMGNT1 |
| GH01G046210 | 0.7 | ENCODE | 12 | -36.7 | -36670 | 1.2 | ZNF639 CTCF LEF1 FOSL1 IRF9 ZNF589 ZNF766 ATF3 POLR2A IKZF1 | RAD54L FAAHP1 POMGNT1 LURAP1 |
| GH01G046190 | 0.4 | dbSUPER | 10.7 | -56.9 | -56881 | 1.1 | CEBPB ZIC2 | POMGNT1 RAD54L ENSG00000226957 LURAP1 PIK3R3 |
| GH01G046191 | 0.4 | dbSUPER | 10.7 | -56.7 | -56737 | 1.2 | CEBPB ZIC2 | POMGNT1 RAD54L ENSG00000226957 LURAP1 PIK3R3 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RAD54L on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RAD54L gene promoter:
Regulatory Element Products
Genomic Location for RAD54L Gene
- Chromosome:
- 1
- Start:
- 46,247,688 bp from pter
- End:
- 46,278,473 bp from pter
- Size:
- 30,786 bases
- Orientation:
- Plus strand
Genomic View for RAD54L Gene
Genes around RAD54L on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p34.1 by Ensembl
- 1p34.1 by Entrez Gene
- 1p34.1 by HGNC
RAD54L Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RAD54L Gene
Proteins for RAD54L Gene
-
Protein details for RAD54L Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92698-RAD54_HUMAN
- Recommended name:
- DNA repair and recombination protein RAD54-like
- Protein Accession:
- Q92698
- Q5TE31
- Q6IUY3
Protein attributes for RAD54L Gene
- Size:
- 747 amino acids
- Molecular mass:
- 84352 Da
- Quaternary structure:
-
- Interacts (via N-terminus) with RAD51.
Protein Expression for RAD54L Gene
Selected DME Specific Peptides for RAD54L Gene
- Q92698:
-
- GTIEEKI
- DEMGLGKT
- LRPHQREG
- DILSKYLPVK
- MGLGKTL
- LMWTLLRQ
- RVWRDGQK
Post-translational modifications for RAD54L Gene
Other Protein References for RAD54L Gene
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for RAD54L
- Cell Signaling Technology (CST) Antibodies for RAD54L (RAD54L)
-
Custom Antibody ServicesOriGene Antibodies for RAD54L
- Novus Biologicals Antibodies for RAD54L
- Invitrogen Antibodies for RAD54L
- antibodies-online Antibodies for RAD54L: See all 15
- GeneTex RAD54L antibody for RAD54L
-
Santa Cruz Biotechnology (SCBT) Antibodies for RAD54L
Protein Products
-
OriGene Purified Proteins for RAD54L
- Search Origene for MassSpec and Protein Over-expression Lysates for RAD54L
- Origene Custom Protein Services for RAD54L
- antibodies-online Proteins for RAD54L: See all 6
- Search antibodies-online for peptides
- Search GeneTex for Proteins for RAD54L
Assay Products
Domains & Families for RAD54L Gene
Protein Domains for RAD54L Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RAD54L Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q92698- Family:
-
- Belongs to the SNF2/RAD54 helicase family.
No data available for Gene Families for RAD54L Gene
Function for RAD54L Gene
Molecular function for RAD54L Gene
- GENATLAS Biochemistry:
- yeast (S cerevisiae) RAD54 homolog,93kDa,SNF2/SW12 family,highly expressed in organs of germ cells and lymphoid development,recombinational protein associated with RAD51,involved in nucleotide excision repair of double-strand break and in meiotic recombination,RAD52 epistasis group,localized in a region of high loss of heterozygosity in breast cancer,potential tumor suppressor in parathyroid adenomas (see TSG1J) and in breast cancer with poor prognosis
- UniProtKB/Swiss-Prot Function:
- Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.
- UniProtKB/Swiss-Prot Induction:
- Expression increases approximately 3-fold in late G1 phase compared to other phases of the cell cycle.
Enzyme Numbers (IUBMB) for RAD54L Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0004386 | helicase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 22153077 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for RAD54L Gene
- MGI mutant phenotypes for RAD54L:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RAD54L:
Animal Models for RAD54L Gene
- MGI Knock Outs for RAD54L:
-
- Rad54l tm1Jhjh
Animal Model Products
-
Taconic Biosciences Mouse Models for RAD54L
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for RAD54L gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RAD54L gene
- Search ViGene Biosciences for RAD54L
CRISPR Products
-
OriGene CRISPR knockouts for RAD54L
-
Santa Cruz Biotechnology (SCBT) CRISPR for RAD54L
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miRNA for RAD54L Gene
- miRTarBase miRNAs that target RAD54L
miRNA Products
- Search ViGene Biosciences for RAD54L
Inhibitory RNA Products
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-
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Clone Products
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- VectorBuilder custom plasmid, inducible vectors for RAD54L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAD54L
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RAD54L
-
ViGene Biosciences adenoviral particle packaged cDNA for RAD54L gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RAD54L gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RAD54L gene
Flow Cytometry Products
No data available for Transcription Factor Targets and HOMER Transcription for RAD54L Gene
Localization for RAD54L Gene
Subcellular locations from UniProtKB/Swiss-Prot for RAD54L Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | TAS | 8805304 |
| GO:0005654 | nucleoplasm | IDA | -- |
Pathways & Interactions for RAD54L Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | ||
| 2 | DNA Damage | ||
| 3 | Integrated Breast Cancer Pathway | ||
Pathways by source for RAD54L Gene
1 Cell Signaling Technology pathway for RAD54L Gene
1 BioSystems pathway for RAD54L Gene
1 KEGG pathway for RAD54L Gene
Interacting Proteins for RAD54L Gene
Selected Interacting proteins:
ENSP00000361043
Q92698-RAD54_HUMAN
for RAD54L Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000724 | double-strand break repair via homologous recombination | IEA | -- |
| GO:0000733 | DNA strand renaturation | IEA | -- |
| GO:0006281 | DNA repair | TAS | 8805304 |
| GO:0006302 | double-strand break repair | IEA | -- |
| GO:0006310 | DNA recombination | TAS | 8805304 |
No data available for SIGNOR curated interactions for RAD54L Gene
Transcripts for RAD54L Gene
mRNA/cDNA for RAD54L Gene
- (5) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (132) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RAD54L Gene
CRISPR Products
-
OriGene CRISPR knockouts for RAD54L
-
Santa Cruz Biotechnology (SCBT) CRISPR for RAD54L
- GenScript: Design CRISPR guide RNA sequences for RAD54L
miRNA Products
- Search ViGene Biosciences for RAD54L
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for RAD54L
- Browse OriGene Inhibitory RNA Products For RAD54L
-
ViGene Biosciences ready-to-package AAV shRNAs for RAD54L gene
Clone Products
- Sino Biological Human cDNA Clone for RAD54L
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RAD54L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAD54L
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 |
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| SP2: | - | ||||||||||||||||||||||||||||||||
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| SP5: |
Expression for RAD54L Gene
mRNA differential expression in normal tissues according to GTEx for RAD54L Gene
This gene is overexpressed in Testis (x6.9).
This gene is overexpressed in Cerebrospinal fluid (35.2), Neutrophil (15.3), Colon (7.2), and Synovial fluid (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RAD54L Gene
NURSA nuclear receptor signaling pathways regulating expression of RAD54L Gene:
RAD54LSOURCE GeneReport for Unigene cluster for RAD54L Gene:
Hs.642042Phenotype-based relationships between genes and organs from Gene ORGANizer for RAD54L Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- immune
- integumentary
- reproductive
- skeletal muscle
Organs:
Thorax:
- breast
General:
- blood
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for RAD54L
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Evidence on tissue expression from TISSUES for RAD54L Gene
Orthologs for RAD54L Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RAD54L 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | RAD54L 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | RAD54L 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Rad54l 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rad54l 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | RAD54L 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | RAD54L 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RAD54L 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | RAD54L 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rad54l 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | rad54l 34 35 |
|
||
| zgc56289 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008748 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | okr 36 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | rad-54 34 35 |
|
||
| Y116A8C.13 36 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RAD54 34 35 37 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AEL297W 34 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0A03069g 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | RAD54 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0762800 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToOne | |
| bread mold (Neurospora crassa) |
Ascomycetes | NCU11255 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | rhp54 34 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.1041 34 |
|
- Species where no ortholog for RAD54L was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for RAD54L Gene
(3) SIMAP similar genes for RAD54L Gene using alignment to 4 proteins:
Variants for RAD54L Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs121908688 | Pathogenic, A colon adenocarcinoma sample | 46,250,097(+) | ACCAC(A/C)TTGTC | reference, missense, utr-variant-5-prime | |
| rs121908689 | Pathogenic, A non-Hodgkin lymphoma sample | 46,272,758(+) | GAGTG(A/T)GTCTT | reference, missense | |
| rs121908690 | Pathogenic, A breast cancer sample | 46,267,540(+) | TCTCC(A/G)GAACT | reference, missense | |
| rs797044888 | Pathogenic | 46,267,600(+) | ATTCC(G/T)GCATC | reference, missense | |
| rs374567435 | Likely pathogenic | 46,274,151(+) | ACGTC(C/T)GCCTG | reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2761743 | CNV | gain | 21179565 |
| esv3585930 | CNV | gain | 21293372 |
| esv3585931 | CNV | gain | 21293372 |
| nsv470711 | CNV | gain | 18288195 |
| nsv829748 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
44.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.88;
48.52% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RAD54L Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAD54L Gene
Disorders for RAD54L Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lymphoma, non-hodgkin |
|
|
| breast cancer |
|
|
| choroid plexus cancer |
|
|
| familial breast cancer |
|
|
| cerebral ventricle cancer |
|
|
Search RAD54L in MalaCards
View complete list of genes associated with diseases
Relevant External Links for RAD54L
No data available for UniProtKB/Swiss-Prot and Genatlas for RAD54L Gene
Publications for RAD54L Gene
- Homologous DNA pairing by human recombination factors Rad51 and Rad54. (PMID: 12205100) Sigurdsson S. … Sung P. (J. Biol. Chem. 2002) 3 4 22 64
- The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA. (PMID: 11459989) Ristic D. … Kanaar R. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3 4 22 64
- Characterization of the human homologue of RAD54: a gene located on chromosome 1p32 at a region of high loss of heterozygosity in breast tumors. (PMID: 9192813) Rasio D. … Croce C.M. (Cancer Res. 1997) 3 4 22 64
- Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation. (PMID: 8805304) Kanaar R. … Hoeijmakers J.H.J. (Curr. Biol. 1996) 2 3 4 64
- Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. (PMID: 20496165) Monsees G.M. … Han J. (Breast Cancer Res. Treat. 2011) 3 46 64
Products for RAD54L Gene
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- Novus Biologicals Antibodies for RAD54L
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- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for RAD54L
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for RAD54L: See all 15
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- antibodies-online Proteins for RAD54L: See all 6
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- GeneTex RAD54L antibody for RAD54L
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- ViGene Biosciences adenoviral particle packaged cDNA for RAD54L gene
- ViGene Biosciences lentiviral particle packaged cDNA for RAD54L gene
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- Search ViGene Biosciences for RAD54L
- Santa Cruz Biotechnology (SCBT) Antibodies for RAD54L
- Search Santa Cruz Biotechnology (SCBT) for RAD54L siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RAD54L
- Horizon Cell Lines for RAD54L
- Cyagen custom Knockout/knockin (KOKI) mouse models for RAD54L
- VectorBuilder custom plasmid, inducible vectors for RAD54L
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAD54L
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RAD54L Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
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