RAD52 Gene
protein-coding GIFtS: 65
GCID: GC12M001021
|
|
RAD52 homolog (S. cerevisiae)(Previous name: RAD52 (S. cerevisiae) homolog )
| |
Aliases
for RAD52 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RAD52 Homolog (S. Cerevisiae)1 2 | | RAD52 (S. Cerevisiae) Homolog1 | | DNA Repair Protein RAD52 Homolog2 | | Recombination Protein RAD522 | | Rhabdomyosarcoma Antigen MU-RMS-40.232 |
Export aliases for RAD52 gene to outside databasesPrevious GC identifers: GC12M000841 GC12M000891 |
Summaries
for RAD52 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RAD52:
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNAdouble-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends,and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found tointeract with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RAD52_HUMAN, P43351Function: Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair bypromoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase
Gene Wiki entry for RAD52
|
Genomic Views
for RAD52 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009759.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RAD52 gene promoter:
p53 GATA-3 ZIC2/Zic2 GATA-1 GATA-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for RAD52
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAD52 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p13-p12.2 Ensembl cytogenetic band: 12p13.33 HGNC cytogenetic band: 12p13-p12.2RAD52 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M001021: view genomic region
(about GC identifiers)
Start:
|
1,021,243 bp from pter |
End:
|
1,100,356 bp from pter |
Size:
|
79,114 bases |
Orientation:
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minus strand |
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Proteins
for RAD52 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RAD52_HUMAN, P43351 (See
protein sequence)Recommended Name: DNA repair protein RAD52 homolog Size: 418 amino acids; 46169 Da
Subunit: Forms a undecameric ring. Interacts with ABL1
Subcellular location: Nucleus (Potential)
2 PDB 3D structures from  and Proteopedia  for RAD52:1H2I (3D)
1KN0 (3D)
Secondary accessions: Q13205Explore the universe of human proteins at neXtProt for RAD52: NX_P43351
Post-translational modifications:
Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P43351
RAD52 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_602296.2
ENSEMBL proteins: ENSP00000351284 ENSP00000434703 ENSP00000387901 ENSP00000439583 ENSP00000436008 ENSP00000440486 ENSP00000441073 ENSP00000380407 ENSP00000443254 ENSP00000438965 ENSP00000445245 ENSP00000440268 Reactome Protein details: P43351
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RAD52 for ontologies About GeneDecksing
RAD52 Antibody Products:
Assay Products for RAD52: |
Protein
Domains /
Families
for RAD52 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RAD52 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P43351ProtoNet protein and cluster: P43351 1 Blocks protein family: IPB007232 Rad52/22 double-strand break repair protein
UniProtKB/Swiss-Prot: RAD52_HUMAN, P43351Similarity: Belongs to the RAD52 family |
Function
for RAD52 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RAD52_HUMAN, P43351Function: Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair bypromoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase Genatlas biochemistry entry for RAD52:yeast (S cerevisiae) RAD52 homolog complexing with phosphorylated BRCA1,BRCA2 and RAD51 for DNA repair of double strandbreaks through homologous recombination,also involved in meiotic recombination,not involved in breast cancer
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAD52 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAD52
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RAD52 (NM_134424) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAD52 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD52 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD52 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
RAD52 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for RAD52:
Animal Models:
Mouse knock-out Rad52tm1Aps for RAD52
8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Rad52):
RAD52 for phenotypes About GeneDecksing
|
Pathways & Interactions
for RAD52 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/10 super-pathways (see all 10) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Assembly of the RAD51-ssDNA nucleoprotein complex | | | 2 | Homologous Recombination Repair | | | 3 | Homologous recombination | | | 4 | Integrated Pancreatic Cancer Pathway | | | 5 | DNA Damage | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for RAD52
2 
Cell Signaling Technology (CST) Pathways for RAD52
5  BioSystems Pathways for RAD52
5/7 
Reactome Pathways for RAD52 (see all 7)
1 
Kegg Pathway (Kegg details for RAD52):
RAD52 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAD52
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/110 Interacting proteins for RAD52 (P433511, 2, 3 ENSP000003512844) via UniProtKB, MINT, STRING, and/or I2D (see all 110)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| WRN | Q141911, 2, 3, ENSP000002981394 | EBI-706448,EBI-368417 MINT-6550741 MINT-17110 MINT-6550731 MINT-6550722 MINT-6550777 MINT-17109 MINT-6550709 MINT-6550679 MINT-6550697 MINT-6550759 I2D:
score=4 STRING: ENSP00000298139 | | RAD51 | Q066091, 2, 3, ENSP000002678684 | EBI-706448,EBI-1059207 MINT-6550637 I2D:
score=4 STRING: ENSP00000267868 | | RPA3 | P352441, 3, ENSP000002231294 | EBI-706448,EBI-1058317 I2D:
score=1 STRING: ENSP00000223129 | | ACTB | P607093, ENSP000003499604 | I2D:
score=1 STRING: ENSP00000349960 | | ARF1 | P840773, ENSP000002721024 | I2D:
score=1 STRING: ENSP00000272102 |
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000724 | double-strand break repair via homologous recombination |
TAS | -- | | GO:0000730 | DNA recombinase assembly |
TAS | -- | | GO:0006281 | DNA repair |
TAS | -- | | GO:0006302 | double-strand break repair |
TAS | -- | | GO:0006310 | DNA recombination |
-- | -- |
RAD52 for ontologies About GeneDecksing
|
Drugs & Compounds
for RAD52 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RAD52 for compounds About GeneDecksing
 Browse Tocris compounds for RAD52
3 Novoseek chemical compound relationships for RAD52 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| methylmethanesulfonate |
60.3 |
5 |
18396468 (3), 11129042 (1) |
| camptothecin |
25.1 |
2 |
8226741 (1), 15929725 (1) |
| cisplatin |
0 |
1 |
16630539 (1) |
Search CenterWatch for drugs/clinical trials and news about RAD52
|
Transcripts
for RAD52 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RAD52 gene (3 alternative transcripts): NM_134424.2 NM_134422.1 NM_134423.1 Unigene Cluster for RAD52: RAD52 homolog (S. cerevisiae) Hs.410355 [show with all ESTs]Unigene Representative Sequence: BC14445818/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23): ENST00000358495(uc001qis.1 uc001qit.1 uc010sdt.1 uc001qiu.1)
ENST00000228345 ENST00000468231 ENST00000481052 ENST00000430095 ENST00000488642(uc001qiw.1)
ENST00000535376 ENST00000542297 ENST00000543912 ENST00000461568(uc001qiv.1 uc001qix.1)
ENST00000463750 ENST00000536177(uc010sdu.1) ENST00000542584 ENST00000545967
ENST00000542785 ENST00000397230 ENST00000544742 ENST00000541619
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAD52 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAD52
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RAD52 (NM_134424) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAD52 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD52 |
Additional cDNA sequence: AF125950.1 AK290047.1 AK292160.1 AK294709.1 AK299283.1 AK312026.1 AY540753.1 BC042136.1 BC104015.1 BC104017.1 BC114507.1 BC114954.1 BC144458.1 L33262.1 U12134.1 U27516.1 13 DOTS entries: DT.413599 DT.438191 DT.121200781 DT.433136 DT.121200733 DT.92459662 DT.95155634 DT.100744024 DT.121200703 DT.121200712 DT.40118108 DT.100739852 DT.95185605 24/118 AceView cDNA sequences (see all 118): AI355618 BI856889 AA256264 CA487440 AW949385 AI418283 BX327490 BQ923202 AA830197 AF125950 AA948349 CA775709 AI220389 AA256360 W87356 AA331560 AI239991 AI142118 AA700287 U27516 AI912590 BQ068945 AW016336 AA292642
GeneLoc Exon Structure
5/16 Alternative Splicing Database (ASD) splice patterns (SP) for RAD52 (see all 16) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d | ^ | 11a | · | 11b | · | 11c | ^ |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | - | | | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | | | - | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d | ^ | 16a | · | 16b | ^ | 17a | · | 17b | ^ | 18a | · | 18b |
|---|
|
| SP1: | | | - | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | |
| SP4: | | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP5: | | | - | | | | | | - | | - | | | | | | | | - | | | | | | | | | |
ECgene alternative splicing isoforms for RAD52
|
Expression
for RAD52 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RAD52 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAACAGAGTT
About this image
See RAD52 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RAD52
SOURCE GeneReport for Unigene cluster: Hs.410355
SABiosciences Expression via Pathway-Focused PCR Arrays including RAD52:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAD52
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RAD52 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAD52 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAD52 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD52 |
Orthologs
for RAD52 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for RAD52 gene from 5/18 species (see all 18) About this table
ENSEMBL Gene Tree for RAD52 (if available)
TreeFam Gene Tree for RAD52 (if available) |
Paralogs
for RAD52 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RAD52 gene
RAD52 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RAD52
PGOHUM00000240444
|
Genomic Variants
for RAD52 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RAD52 (1021243 - 1100356 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RAD52
1 CNV: 101394
Human Gene Mutation Database (HGMD): RAD52
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAD52 |
|
Disorders
/ Diseases
for RAD52 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RAD52 for disorders About GeneDecksing
OMIM gene information: 600392
OMIM disorders: --
20/30  diseases for RAD52 (see all 30): About MalaCardsdna topoisomerase i nijmegen breakage syndrome acoustic neuroma familial chronic lymphocytic leukemia
chronic lymphocytic leukemia neuroma lymphocytic leukemia breast cancer susceptibility
bloom syndrome breast-ovarian cancer ovarian cancer epithelial ovarian cancer
werner syndrome breast cancer stomach cancer prostate cancer, progression of
multiple sclerosis lung cancer prostate cancer pulmonary disease
5 Novoseek disease relationships for RAD52 gene About this table
Genetic Association Database (GAD): RAD52
Human Genome Epidemiology (HuGE) Navigator: RAD52 (35 documents)
Export disorders for RAD52 gene to outside databases
|
Publications
for RAD52 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RAD52 gene, integrated from 9 sources (see all 158):
(articles sorted by number of sources associating them with RAD52) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human and mouse homologs of the yeast RAD52 gene: cDNA cloning, sequence analysis, assignment to human chromosome 12p12.2-p13, and mRNA expression in mouse tissues. (PubMed id 7774919)1, 2, 3, 9 Shen Z.... Chen D.J. (1995)
- Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation. (PubMed id 12379650)1, 2, 9 Kitao H. and Yuan Z.M. (2002)
- Rad52 gene mutations in breast/ovarian cancer families and sporadic ovarian carcinoma patients. (PubMed id 12883740)1, 4, 9 Tong D....Zeillinger R. (2003)
- Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination. (PubMed id 7526206)1, 2, 9 Muris D.F.... Pastink A. (1994)
- Structure of the single-strand annealing domain of human RAD52 protein. (PubMed id 12370410)1, 2, 9 Singleton M.R.... Wigley D.B. (2002)
- DNA repair synthesis facilitates RAD52-mediated second-end capture during DSB repair. (PubMed id 18313388)1, 3, 9 McIlwraith M.J. and West S.C. (2008)
- Variants in DNA double-strand break repair genes and breast cancer susceptibility. (PubMed id 12023982)1, 4, 9 Kuschel B....Dunning A. (2002)
- RAD52 Y415X truncation polymorphism and epithelial ovarian cancer risk in Australian women. (PubMed id 15670896)1, 4, 9 Kelemen L....Chenevix-Trench G. (2005)
- Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk. (PubMed id 15958648)1, 4 Lee K.M....Kang D. (2005)
- Effect of germ-line genetic variation on breast cancer survival in a population-based study. (PubMed id 12036913)1, 4 Goode E.L....Pharoah P.P. (2002)
|
External Searches for RAD52 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RAD52 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RAD52 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAD52 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RAD52 gene:
Search GeneIP for patents involving RAD52
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RAD52 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for RAD52 | | OriGene shRNA RFP for RAD52 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAD52 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAD52 | | | OriGene Protein Over-expression Lysate for RAD52 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RAD52 | | OriGene 3'-UTR Clone for RAD52 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAD52 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAD52 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RAD52 | | OriGene Custom Protein Services for RAD52 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RAD52 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAD52 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAD52 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAD52 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAD52 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAD52 |
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| | Antibodies & Assays for RAD52 |
| | | | Search Tocris compounds for RAD52 |
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 | | | RAD52 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD52 |
|  |  |  | | | | ThermoFisher Antibodies for RAD52 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD52 |
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