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Aliases for RAD51L3-RFFL Gene

Subcategory (RNA class) for RAD51L3-RFFL Gene


Quality Score for this RNA gene is


Aliases for RAD51L3-RFFL Gene

  • RAD51L3-RFFL Readthrough 3

External Ids for RAD51L3-RFFL Gene

Previous GeneCards Identifiers for RAD51L3-RFFL Gene

  • GC17U901597
  • GC17M033336

Summaries for RAD51L3-RFFL Gene

Entrez Gene Summary for RAD51L3-RFFL Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RAD51-like 3 (RAD51L3) and ring finger and FYVE-like domain containing 1 (RFFL) genes on chromosome 17. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Jan 2011]

GeneCards Summary for RAD51L3-RFFL Gene

RAD51L3-RFFL (RAD51L3-RFFL Readthrough) is an RNA Gene, and is affiliated with the ncRNA class.

Additional gene information for RAD51L3-RFFL Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAD51L3-RFFL Gene

Genomics for RAD51L3-RFFL Gene

GeneHancer (GH) Regulatory Elements for RAD51L3-RFFL Gene

Promoters and enhancers for RAD51L3-RFFL Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I035121 Promoter 0.5 EPDnew 550.8 -0.1 -90 0.1 FNDC8 GC17M035118 RAD51D RAD51L3-RFFL ENSG00000267618 PIR40636
GH17I035119 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.8 +2.1 2065 2 ARID4B SIN3A ZNF2 E2F8 ZNF207 ZNF143 KLF13 SP3 MXD4 REST GC17M035118 RAD51D LIG3 ZNF830 RAD51L3-RFFL ENSG00000267618 ENSG00000252328
GH17I035083 Promoter/Enhancer 2.3 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +34.4 34359 6.6 HDGF PKNOX1 FOXA2 SMAD1 MLX ARID4B SIN3A DMAP1 IRF4 YY1 LIG3 RFFL SLFN5 ZNF830 CCT6B NLE1 RPL37P22 RAD51L3-RFFL ENSG00000267618
GH17I035118 Enhancer 0.6 ENCODE 0.8 +3.3 3314 0.1 CTCF PKNOX1 TRIM22 ZNF143 EBF1 DPF2 RAD21 ZKSCAN1 GC17M035118 RAD51D RAD51L3-RFFL ENSG00000267618 ENSG00000252328
GH17I035062 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.2 +57.3 57295 3.9 PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 RFFL LIG3 RNU6-840P CCT6B GC17M035056 GC17P035052 ENSG00000267457 RAD51L3-RFFL ENSG00000267618
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RAD51L3-RFFL on UCSC Golden Path with GeneCards custom track

Genomic Locations for RAD51L3-RFFL Gene

Genomic Locations for RAD51L3-RFFL Gene
112,411 bases
Minus strand

Genomic View for RAD51L3-RFFL Gene

Genes around RAD51L3-RFFL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RAD51L3-RFFL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RAD51L3-RFFL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAD51L3-RFFL Gene

Proteins for RAD51L3-RFFL Gene

Post-translational modifications for RAD51L3-RFFL Gene

No Post-translational modifications

No data available for DME Specific Peptides for RAD51L3-RFFL Gene

Domains & Families for RAD51L3-RFFL Gene

Gene Families for RAD51L3-RFFL Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RAD51L3-RFFL: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RAD51L3-RFFL Gene

Function for RAD51L3-RFFL Gene

Phenotypes From GWAS Catalog for RAD51L3-RFFL Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RAD51L3-RFFL Gene

Localization for RAD51L3-RFFL Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RAD51L3-RFFL Gene

Pathways & Interactions for RAD51L3-RFFL Gene

SuperPathways for RAD51L3-RFFL Gene

No Data Available

Interacting Proteins for RAD51L3-RFFL Gene

Gene Ontology (GO) - Biological Process for RAD51L3-RFFL Gene


No data available for Pathways by source and SIGNOR curated interactions for RAD51L3-RFFL Gene

Drugs & Compounds for RAD51L3-RFFL Gene

No Compound Related Data Available

Transcripts for RAD51L3-RFFL Gene

Alternative Splicing Database (ASD) splice patterns (SP) for RAD51L3-RFFL Gene

No ASD Table

Relevant External Links for RAD51L3-RFFL Gene

GeneLoc Exon Structure for

No data available for mRNA/cDNA for RAD51L3-RFFL Gene

Expression for RAD51L3-RFFL Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RAD51L3-RFFL Gene

Orthologs for RAD51L3-RFFL Gene

No data available for Orthologs and Evolution for RAD51L3-RFFL Gene

Paralogs for RAD51L3-RFFL Gene

No data available for Paralogs for RAD51L3-RFFL Gene

Variants for RAD51L3-RFFL Gene

Sequence variations from dbSNP and Humsavar for RAD51L3-RFFL Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1001440122 likely-benign, uncertain-significance, not specified, Breast-ovarian cancer, familial 4, Hereditary cancer-predisposing syndrome 35,103,328(-) C/A/T intron_variant
rs1040279995 uncertain-significance, Hereditary cancer-predisposing syndrome 35,103,288(-) T/A non_coding_transcript_variant
rs1044486334 uncertain-significance, Hereditary cancer-predisposing syndrome 35,119,558(-) A/G intron_variant
rs1056851142 uncertain-significance, Hereditary cancer-predisposing syndrome 35,101,340(-) C/T non_coding_transcript_variant
rs1057517586 likely-pathogenic, Breast-ovarian cancer, familial 4 35,119,170(-) CC/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for RAD51L3-RFFL Gene

Variant ID Type Subtype PubMed ID
esv3640438 CNV loss 21293372
esv3892998 CNV loss 25118596
nsv2035 CNV deletion 18451855

Variation tolerance for RAD51L3-RFFL Gene

Gene Damage Index Score: 5.26; 70.19% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Additional Variant Information for RAD51L3-RFFL Gene

Disorders for RAD51L3-RFFL Gene

Additional Disease Information for RAD51L3-RFFL

No disorders were found for RAD51L3-RFFL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAD51L3-RFFL Gene

Publications for RAD51L3-RFFL Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for RAD51L3-RFFL Gene

Sources for RAD51L3-RFFL Gene

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