RAD51AP2 Gene
protein-coding GIFtS: 32
GCID: GC02M017691
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RAD51 associated protein 2
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Aliases
for RAD51AP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RAD51 Associated Protein 21 2 | | FLJ175401 | | RAD51-Associated Protein 22 |
Export aliases for RAD51AP2 gene to outside databasesPrevious GC identifer: GC02M017556 |
Summaries
for RAD51AP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RAD51AP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_015926.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RAD51AP2 gene promoter:
ATF-2 HSF1 (long) NF-AT POU2F1 NF-AT2 POU2F1a HSF1short NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RAD51AP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAD51AP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p24.2 Ensembl cytogenetic band: 2p24.2 HGNC cytogenetic band: 2p24.2RAD51AP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M017691: view genomic region
(about GC identifiers)
Start:
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17,691,851 bp from pter |
End:
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17,699,706 bp from pter |
Size:
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7,856 bases |
Orientation:
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minus strand |
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Proteins
for RAD51AP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: R51A2_HUMAN, Q09MP3 (See
protein sequence)Recommended Name: RAD51-associated protein 2 Size: 1159 amino acids; 133907 Da
Subunit: Interacts with RAD51Explore the universe of human proteins at neXtProt for RAD51AP2: NX_Q09MP3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q09MP3
RAD51AP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001092688.1
ENSEMBL proteins: ENSP00000382030
Human Recombinant Protein Products:
RAD51AP2 Antibody Products:
Assay Products for RAD51AP2: |
Protein
Domains /
Families
for RAD51AP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q09MP3 |
Function
for RAD51AP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAD51AP2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAD51AP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RAD51AP2 (NM_001099218) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAD51AP2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RAD51AP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD51AP2 |
1 GenomeRNAi human phenotype for RAD51AP2:
|
Pathways & Interactions
for RAD51AP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RAD51AP2
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for RAD51AP2 (Q09MP33 ENSP000003820304) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for RAD51AP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RAD51AP2
Search CenterWatch for drugs/clinical trials and news about RAD51AP2 / R51A2
|
Transcripts
for RAD51AP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RAD51AP2 gene: NM_001099218.2 Unigene Cluster for RAD51AP2: RAD51 associated protein 2 Hs.722353 [show with all ESTs]Unigene Representative Sequence: DQ8601021 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000399080(uc002rcl.1 uc010exn.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAD51AP2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAD51AP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RAD51AP2 (NM_001099218) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAD51AP2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RAD51AP2 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAD51AP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RAD51AP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAD51AP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAD51AP2 |
Additional cDNA sequence: DQ860102.1 1 DOTS entry: DT.40305565
GeneLoc Exon Structure
|
Expression
for RAD51AP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RAD51AP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGTAGGCCA
About this image
See RAD51AP2 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.722353
UniProtKB/Swiss-Prot: R51A2_HUMAN, Q09MP3Tissue specificity: Specifically expressed in meiotic tissues. Highly expressed in testis
SABiosciences Custom PCR Arrays for RAD51AP2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAD51AP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RAD51AP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAD51AP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAD51AP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD51AP2 |
Orthologs
for RAD51AP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for RAD51AP2 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for RAD51AP2 (if available)
TreeFam Gene Tree for RAD51AP2 (if available) |
Paralogs
for RAD51AP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for RAD51AP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for RAD51AP2 (17691851 - 17699706 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RAD51AP2
1 CNV: 89508 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAD51AP2 |
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Disorders
/ Diseases
for RAD51AP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for RAD51AP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RAD51AP2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RAD51AP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51. (PubMed id 16990250)1, 2, 3 Kovalenko O.V....Schild D. (2006)
- Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
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External Searches for RAD51AP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RAD51AP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RAD51AP2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAD51AP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RAD51AP2 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for RAD51AP2 gene:
Search GeneIP for patents involving RAD51AP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RAD51AP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RAD51AP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAD51AP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAD51AP2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RAD51AP2 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAD51AP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAD51AP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RAD51AP2 | | OriGene Custom Protein Services for RAD51AP2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RAD51AP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAD51AP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAD51AP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAD51AP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAD51AP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAD51AP2 |
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 | | | RAD51AP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD51AP2 |
|  |  |  | | | | Search ThermoFisher Antibodies for RAD51AP2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RAD51AP2 |
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