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Aliases for RAD51AP2 Gene

Aliases for RAD51AP2 Gene

  • RAD51 Associated Protein 2 2 3

External Ids for RAD51AP2 Gene

Previous GeneCards Identifiers for RAD51AP2 Gene

  • GC02M017556
  • GC02M017691

Summaries for RAD51AP2 Gene

GeneCards Summary for RAD51AP2 Gene

RAD51AP2 (RAD51 Associated Protein 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAD51AP2 Gene

Genomics for RAD51AP2 Gene

Regulatory Elements for RAD51AP2 Gene

Genomic Location for RAD51AP2 Gene

Chromosome:
2
Start:
17,510,584 bp from pter
End:
17,520,580 bp from pter
Size:
9,997 bases
Orientation:
Minus strand

Genomic View for RAD51AP2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAD51AP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAD51AP2 Gene

Proteins for RAD51AP2 Gene

  • Protein details for RAD51AP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q09MP3-R51A2_HUMAN
    Recommended name:
    RAD51-associated protein 2
    Protein Accession:
    Q09MP3

    Protein attributes for RAD51AP2 Gene

    Size:
    1159 amino acids
    Molecular mass:
    133907 Da
    Quaternary structure:
    • Interacts with RAD51.

neXtProt entry for RAD51AP2 Gene

Proteomics data for RAD51AP2 Gene at MOPED

Post-translational modifications for RAD51AP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAD51AP2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAD51AP2 Gene

Domains & Families for RAD51AP2 Gene

Protein Domains for RAD51AP2 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for RAD51AP2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RAD51AP2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for RAD51AP2 Gene

Function for RAD51AP2 Gene

Phenotypes for RAD51AP2 Gene

GenomeRNAi human phenotypes for RAD51AP2:
genes like me logo Genes that share phenotypes with RAD51AP2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAD51AP2 Gene

Localization for RAD51AP2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RAD51AP2 Gene

Pathways & Interactions for RAD51AP2 Gene

SuperPathways for RAD51AP2 Gene

No Data Available

Interacting Proteins for RAD51AP2 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000382030%0d%0a9606.ENSP00000372088%0d%0a
Selected Interacting proteins: ENSP00000382030 Q09MP3-R51A2_HUMAN for RAD51AP2 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for RAD51AP2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RAD51AP2 Gene

Drugs & Compounds for RAD51AP2 Gene

No Compound Related Data Available

Transcripts for RAD51AP2 Gene

mRNA/cDNA for RAD51AP2 Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAD51AP2 Gene

RAD51 associated protein 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RAD51AP2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RAD51AP2 Gene

No ASD Table

Relevant External Links for RAD51AP2 Gene

GeneLoc Exon Structure for
RAD51AP2
ECgene alternative splicing isoforms for
RAD51AP2

Expression for RAD51AP2 Gene

mRNA expression in normal human tissues for RAD51AP2 Gene

mRNA differential expression in normal tissues according to GTEx for RAD51AP2 Gene

This gene is overexpressed in Testis (x29.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RAD51AP2 Gene



SOURCE GeneReport for Unigene cluster for RAD51AP2 Gene Hs.722353

mRNA Expression by UniProt/SwissProt for RAD51AP2 Gene

Q09MP3-R51A2_HUMAN
Tissue specificity: Specifically expressed in meiotic tissues. Highly expressed in testis.
genes like me logo Genes that share expression patterns with RAD51AP2: view

Protein tissue co-expression partners for RAD51AP2 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein differential expression in normal tissues for RAD51AP2 Gene

Orthologs for RAD51AP2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RAD51AP2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RAD51AP2 35
  • 80.59 (n)
  • 63.88 (a)
RAD51AP2 36
  • 63 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RAD51AP2 35
  • 76.71 (n)
  • 58.97 (a)
RAD51AP2 36
  • 58 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rad51ap2 35
  • 73.32 (n)
  • 54.05 (a)
Rad51ap2 16
Rad51ap2 36
  • 53 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RAD51AP2 35
  • 98.96 (n)
  • 97.76 (a)
RAD51AP2 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rad51ap2 35
  • 73.33 (n)
  • 54.36 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia RAD51AP2 36
  • 33 (a)
OneToOne
Species with no ortholog for RAD51AP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RAD51AP2 Gene

ENSEMBL:
Gene Tree for RAD51AP2 (if available)
TreeFam:
Gene Tree for RAD51AP2 (if available)

Paralogs for RAD51AP2 Gene

No data available for Paralogs for RAD51AP2 Gene

Variants for RAD51AP2 Gene

Sequence variations from dbSNP and Humsavar for RAD51AP2 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs404979 -- 17,510,402(-) TCAAG(A/G)TCACA downstream-variant-500B
rs421302 -- 17,520,276(-) AATAG(C/G)CATTG upstream-variant-2KB, intron-variant
rs665312 -- 17,517,411(-) CTCAG(C/T)AGCCA synonymous-codon, reference
rs1401704 -- 17,522,371(+) TCTTA(C/G)TTAGG upstream-variant-2KB
rs5829595 -- 17,519,308(+) CAGTC(-/A)AATTC upstream-variant-2KB, intron-variant

Variation tolerance for RAD51AP2 Gene

Residual Variation Intolerance Score: 70.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.86; 58.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RAD51AP2 Gene

HapMap Linkage Disequilibrium report
RAD51AP2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RAD51AP2 Gene

Disorders for RAD51AP2 Gene

Relevant External Links for RAD51AP2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RAD51AP2
genes like me logo Genes that share disorders with RAD51AP2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAD51AP2 Gene

Publications for RAD51AP2 Gene

  1. RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51. (PMID: 16990250) Kovalenko O.V. … Schild D. (Nucleic Acids Res. 2006) 2 67
  2. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 67

Products for RAD51AP2 Gene

Sources for RAD51AP2 Gene

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