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RAD51AP1 Gene

protein-coding   GIFtS: 50
GCID: GC12P004647

RAD51 Associated Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAD51 Associated Protein 11 2
PIR512 3 5
RAD51-Interacting Protein2 3
RAD51-Associated Protein 12

External Ids:    HGNC: 169561   Entrez Gene: 106352   Ensembl: ENSG000001112477   OMIM: 6030705   UniProtKB: Q96B013   

Export aliases for RAD51AP1 gene to outside databases

Previous GC identifer: GC12P004519


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAD51AP1 Gene:
RAD51AP1 (RAD51 associated protein 1) is a protein-coding gene. Diseases associated with RAD51AP1 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. GO annotations related to this gene include single-stranded DNA binding and RNA binding.

UniProtKB/Swiss-Prot: R51A1_HUMAN, Q96B01
Function: May participate in a common DNA damage response pathway associated with the activation of homologous
recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation
by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RAD51AP1 gene promoter:
         E2F-3a   E2F-4   E2F-5   E2F-2   RORalpha2   PPAR-gamma1   E2F-1   E2F   POU2F1a   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAD51AP1 promoter sequence
   Search Chromatin IP Primers for RAD51AP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAD51AP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.2-p13.1   Ensembl cytogenetic band:  12p13.32   HGNC cytogenetic band: 12p13.2-p13.1

RAD51AP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAD51AP1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P004647:  view genomic region     (about GC identifiers)

Start:
4,647,950 bp from pter      End:
4,669,214 bp from pter
Size:
21,265 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: R51A1_HUMAN, Q96B01 (See protein sequence)
Recommended Name: RAD51-associated protein 1  
Size: 352 amino acids; 38457 Da
Subunit: Isoform 2 interacts with RAD51. Interacts with PALB2. Interacts (via C-terminus region) with RAD51; the
interaction is direct
Secondary accessions: A8K7D3 O43403 Q7Z779
Alternative splicing: 3 isoforms:  Q96B01-1   Q96B01-2   Q96B01-3   

Explore the universe of human proteins at neXtProt for RAD51AP1: NX_Q96B01

Explore proteomics data for RAD51AP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAD51AP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001124334.1  NP_006470.1  

    ENSEMBL proteins: 
     ENSP00000443837   ENSP00000438172   ENSP00000446002   ENSP00000439925   ENSP00000438422  
     ENSP00000399859   ENSP00000228843   ENSP00000309479   ENSP00000442890   ENSP00000446296  
     ENSP00000444769   ENSP00000439019   ENSP00000323750   ENSP00000439960  

    RAD51AP1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RAD51AP1

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    Cloud-Clone Corp. ELISAs for RAD51AP1
    Cloud-Clone Corp. CLIAs for RAD51AP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026632 RAD51-assoc_prot_1

    Graphical View of Domain Structure for InterPro Entry Q96B01

    ProtoNet protein and cluster: Q96B01


    RAD51AP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: R51A1_HUMAN, Q96B01
    Function: May participate in a common DNA damage response pathway associated with the activation of homologous
    recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation
    by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003690double-stranded DNA binding IDA9396801
    GO:0003697single-stranded DNA binding IDA9396801
    GO:0003723RNA binding IDA9396801
    GO:0005515protein binding IPI--
         
    RAD51AP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RAD51AP1:
     Decreased homologous recombina 

         1 MGI phenotypic allele for Rad51ap1 (no phenotypes)

    RAD51AP1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAD51AP1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAD51AP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAD51AP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAD51AP1

    miRNA
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    miRTarBase miRNAs that target RAD51AP1:
    hsa-mir-124-3p (MIRT022219), hsa-mir-346 (MIRT042708)

    Block miRNA regulation of human, mouse, rat RAD51AP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAD51AP1 (see all 10):
    hsa-miR-3163 hsa-miR-3671 hsa-miR-130a* hsa-miR-548e hsa-miR-23c hsa-miR-888* hsa-miR-548a-3p hsa-miR-587
    SwitchGear 3'UTR luciferase reporter plasmidRAD51AP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAD51AP1

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    GenScript: all cDNA clones in your preferred vector (see all 2): RAD51AP1 (NM_001130862)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAD51AP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD51AP1

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    Browse ESI BIO Cell Lines and PureStem Progenitors for RAD51AP1 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD51AP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    R51A1_HUMAN, Q96B01: Nucleus (By similarity). Note=Colocalizes with RAD51 to multiple nuclear foci (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC9396801

    RAD51AP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAD51AP1
    Interactions:

        GeneGlobe Interaction Network for RAD51AP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for RAD51AP1 (Q96B011, 3 ENSP000002288434) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAD51Q066091, 3, ENSP000002678684EBI-1178748,EBI-297202 I2D: score=3 STRING: ENSP00000267868
    USP12O753173, ENSP000002823444I2D: score=2 STRING: ENSP00000282344
    WDR48Q8TAF33, ENSP000003074914I2D: score=2 STRING: ENSP00000307491
    PALB2Q86YC23, ENSP000002615844I2D: score=1 STRING: ENSP00000261584
    USP46P620683, ENSP000004078184I2D: score=2 STRING: ENSP00000407818
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000724double-strand break repair via homologous recombination NAS9396801
    GO:0006281DNA repair NAS9396801
    GO:0006310DNA recombination ----
    GO:0010569regulation of double-strand break repair via homologous recombination IDA--
    GO:0071479cellular response to ionizing radiation IDA--

    RAD51AP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAD51AP1 (R51A1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAD51AP1 gene (2 alternative transcripts): 
    NM_001130862.1  NM_006479.4  

    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000536346 ENST00000536886 ENST00000544110 ENST00000398012 ENST00000535558
    ENST00000442992 ENST00000228843(uc001qmw.3) ENST00000352618(uc001qmu.3 uc010sep.2 uc010seq.2 uc009zeg.3)
    ENST00000538817 ENST00000544927 ENST00000536117 ENST00000544173 ENST00000544029
    ENST00000544931 ENST00000321524 ENST00000543041
    miRNA
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    Block miRNA regulation of human, mouse, rat RAD51AP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAD51AP1 (see all 10):
    hsa-miR-3163 hsa-miR-3671 hsa-miR-130a* hsa-miR-548e hsa-miR-23c hsa-miR-888* hsa-miR-548a-3p hsa-miR-587
    SwitchGear 3'UTR luciferase reporter plasmidRAD51AP1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RAD51AP1
    Predesigned siRNA for gene silencing in human, mouse, rat RAD51AP1
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RAD51AP1 (NM_001130862)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAD51AP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAD51AP1
    Primer
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    OriGene qPCR primer pairs and template standards for RAD51AP1
    OriGene qSTAR qPCR primer pairs in human, mouse for RAD51AP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAD51AP1
      QuantiTect SYBR Green Assays in human, mouse, rat RAD51AP1
      QuantiFast Probe-based Assays in human, mouse, rat RAD51AP1

    Selected AceView cDNA sequences (see all 133):

    AV717411 BX424561 AI424788 AL597257 CR625391 AF006259 BM827863 AA948649 
    AK096930 BM669611 AA232231 BM460312 BM541402 BM817670 CB159768 AA626685 
    BM698829 BU165840 BU662851 AW592917 AA577374 BQ438867 AA730059 AW002924 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RAD51AP1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                                      -                                             
    SP2:                                      -     -                                       
    SP3:                                      -     -     -                                 
    SP4:                                            -                                       
    SP5:                                                                                    


    ECgene alternative splicing isoforms for RAD51AP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAD51AP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAGCTGTTA
    RAD51AP1 Expression
    About this image

    RAD51AP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAD51AP1 Protein Expression

    UniProtKB/Swiss-Prot: R51A1_HUMAN, Q96B01
    Tissue specificity: Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no
    expression in spleen, prostate, ovary and peripheral blood leukocytes

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAD51AP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for RAD51AP1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rad51ap11 , 5 RAD51 associated protein 11, 5 72.31(n)1
    61.63(a)1
      6 (61.92 cM)5
    193621  NM_009013.31  NP_033039.21 
     1269230505 
    chicken
    (Gallus gallus)
    Aves RAD51AP11 RAD51 associated protein 1 58.01(n)
    43.42(a)
      419042  XM_417234.4  XP_417234.4 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.244632 Xenopus laevis transcribed sequence with weak similarity more 69.83(n)    BG515802.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rad51ap11 RAD51 associated protein 1 46.32(n)
    38.55(a)
      555714  NM_001044338.2  NP_001037803.2 


    ENSEMBL Gene Tree for RAD51AP1 (if available)
    TreeFam Gene Tree for RAD51AP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAD51AP1 gene

    RAD51AP1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RAD51AP1
    PGOHUM00000237784


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAD51AP1 (see all 406)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs782779091,2
    C,F--4649676(+) AAATTG/ATACTA 2 -- int11Minor allele frequency- A:0.17NA 120
    rs1811902641,2
    --4649696(+) GCAATA/GTTTAC 2 -- int10--------
    rs343228981,2
    C--4649720(+) AAAAAA/-TCATT 2 -- int11Minor allele frequency- -:0.00NA 2
    rs1136335631,2
    C--4649720(+) AAAGT-/AAAAAA 2 -- int11Minor allele frequency- A:0.00CSA 2
    rs732554401,2
    C,F--4649798(+) GCTTAA/GCCCTT 2 -- int12Minor allele frequency- G:0.15WA 120
    rs740619521,2
    C,F--4649924(+) AGAGAG/ATAATA 2 -- int11Minor allele frequency- A:0.50WA 2
    rs1859446851,2
    --4649953(+) GTTTGC/TGTGAG 2 -- int10--------
    rs1903558451,2
    --4649954(+) TTTGCA/GTGAGG 2 -- int10--------
    rs108490871,2
    C,F,A,H--4650065(+) TACCTC/TTTTTT 2 -- int1 trp321Minor allele frequency- T:0.24NS EA NA WA CSA 2145
    rs1476231271,2
    --4650088(+) TTTTTA/GCTTGA 2 -- int10--------

    HapMap Linkage Disequilibrium report for RAD51AP1 (4647950 - 4669214 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RAD51AP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv832318CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAD51AP1
    DNA2.0 Custom Variant and Variant Library Synthesis for RAD51AP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603070    OMIM disorders: --

    7 diseases for RAD51AP1:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    hepatocellular carcinoma    ovarian cancer
    colorectal cancer    prostatitis    neuronitis


    RAD51AP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RAD51AP1
    Human Genome Epidemiology (HuGE) Navigator: RAD51AP1 (2 documents)

    Export disorders for RAD51AP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAD51AP1 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with RAD51AP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel nucleic acid-binding protein that interacts with human rad51 recombinase. (PubMed id 9396801)1, 2, 3 Kovalenko O.V.... Radding C.M. (Nucleic Acids Res. 1997)
    2. Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. (PubMed id 20871616)1, 2 Dray E.... Sung P. (Nat. Struct. Mol. Biol. 2010)
    3. Human variation in alcohol response is influenced by variation in neuronal signaling genes. (PubMed id 20201926)1, 4 Joslyn G....White R.L. (Alcohol. Clin. Exp. Res. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement. (PubMed id 17996711)1, 9 Wiese C....Schild D. (Mol. Cell 2007)
    7. Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma. (PubMed id 14966907)1, 9 Song H....Zhao M.J. (World J. Gastroenterol. 2004)
    8. RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51. (PubMed id 16990250)2, 9 Kovalenko O.V.... Schild D. (Nucleic Acids Res. 2006)
    9. FIGNL1-containing protein complex is required for efficient homologous recombination repair. (PubMed id 23754376)2 Yuan J. and Chen J. (Proc. Natl. Acad. Sci. U.S.A. 2013)
    10. Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. (PubMed id 23263487)1 Jia W.H....Zheng W. (Nat. Genet. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10635 HGNC: 16956 AceView: RAD51AP1 Ensembl:ENSG00000111247 euGenes: HUgn10635
    ECgene: RAD51AP1 H-InvDB: RAD51AP1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAD51AP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAD51AP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAD51AP1 gene:
    Search GeneIP for patents involving RAD51AP1

    GeneCards and IP:
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