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RAD1 Gene

protein-coding   GIFtS: 60

GC05M034944
RAD1 homolog (S. pombe)
(Previous name: RAD1 (S. pombe) homolog )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for RAD1

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
EC 3.1.11.2 3
HRAD1 1, 2
OTTHUMP00000115992 2
REC1 1, 2, 3
hRAD1 3
Descriptions
DNA repair exonuclease REC1 2
DNA repair exonuclease rad1 homolog 3
RAD1 (S. pombe) homolog 1
RAD1 homolog 2
RAD1 homolog (S. pombe) 2
Rad1-like DNA damage checkpoint 2
Rad1-like DNA damage checkpoint protein 3
cell cycle checkpoint protein Hrad1 2
checkpoint control protein HRAD1 2
exonuclease homolog RAD1 2
External Ids
HGNC: 98061
Entrez Gene: 58102
UniProtKB: O606713
Ensembl: ENSG000001134567
Search outside databases for aliases for RAD1 gene

Previous GC identifers: GC05M034941 GC05M035934 GC05M034953

Summaries
for RAD1

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for RAD1:
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1
complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete
DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract
specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript
variants of this gene have been described. [provided by RefSeq]

UniProtKB/Swiss-Prot: RAD1_HUMAN, O60671
Function: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in
DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication
factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several
proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA
polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the
primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1
cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths;
and DNA ligase I (LIG1) on long-patch base excision repair substrates. Isoform 1 possesses 3'->5'
double stranded DNA exonuclease activity

Gene Wiki entry for RAD1 (RAD1_homolog)

Genomic Location
for RAD1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the RAD1 gene  

Entrez Gene cytogenetic band: 5p13.2   Ensembl cytogenetic band:  5p13.2   HGNC cytogenetic band: 5p13

RAD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M034944:     (about GC identifiers)

Start:
 34,938,268 bp from pter
End:
 34,954,139 bp from pter
Size:
 15,872 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000005.8  NT_006576.15  

Proteins
for RAD1

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: RAD1_HUMAN, O60671 (See protein sequence)
Recommended Name: Cell cycle checkpoint protein RAD1  
Size: 282 amino acids; 31827 Da
Subunit: Component of the toroidal 9-1-1 (RAD9-RAD1-HUS1) complex, composed of RAD9A, RAD1 and
HUS1. The 9-1-1 complex associates with LIG1, POLB, FEN1, RAD17, HDAC1, RPA1 and RPA2. The 9-1-1
complex associates with the RAD17-RFC complex. RAD1 interacts with POLB, FEN1, HUS1, HUS1B, RAD9A
and RAD9B
Subcellular location: Nucleus
Secondary accessions: O75572 O95304 Q1W161 Q5KSM0 Q5KSM1 Q9UEP1
Alternative splicing: 3 isoforms:  O60671-1   O60671-2   O60671-3   

REFSEQ proteins (2 alternative transcripts): 
NP_002844.1  NP_596868.1  


ENSEMBL proteins: 
ENSP00000313467 ENSP00000340879 ENSP00000231383 ENSP00000371469 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (Rad1)
Human Recombinant Proteins from Abnova (RAD1)
              OriGene Purified Recombinant Human Protein: RAD1 

1 Gene Ontology (GO) cellular component term (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005634 nucleus IC9660799
About this table

Antibodies for RAD1: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibody Arrays and Antibodies for RAD1
Browse R&D Systems for Antibodies
Antibodies from Abcam (Rad1), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (RAD1)
Novus Biologicals Antibodies for RAD1

Assays for RAD1: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for RAD1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
2 InterPro domains/families:
 IPR003011 Rad1_repair
 IPR003021 Rad1_Rec1


   GeneDecks  RAD1 for the domains selected above  
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Graphical View of Domain Structure for InterPro Entry O60671

ProtoNet protein and cluster: O60671

2 Blocks protein families:
IPB003011 Rad1 repair protein signature
IPB003021 Repair protein Rad1/Rec1 family signature


UniProtKB/Swiss-Prot: RAD1_HUMAN, O60671
Similarity: Belongs to the rad1 family

Gene Function
for RAD1

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (RAD1)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (RAD1)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5): NR_026591

              Applied Biosystems Silencer® siRNAs for RAD1

              Sigma-Aldrich siRNA and siRNA Panels for RAD1  
                     Sigma-Aldrich shRNA for RAD1  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for RAD1
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002853
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002853
                                 untagged cDNA clones in CMV expression vector (see all 6): BC009804 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_133377

UniProtKB/Swiss-Prot: RAD1_HUMAN, O60671
Function: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in
DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication
factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several
proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA
polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the
primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1
cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths;
and DNA ligase I (LIG1) on long-patch base excision repair substrates. Isoform 1 possesses 3'->5'
double stranded DNA exonuclease activity
Catalytic activity: Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside
5'-phosphates
Enzyme Number (IUBMB): EC 3.1.11.2 

Genatlas biochemistry entry for RAD1:
cell cycle G2 checkpoint control gene,also involved in DNA repair,homologous to RAD17,S pombe
Rad1,S.cerevisiae,with two alternatively spliced isoforms (large RAD1-b and short
RAD1-c),ubiquitously expressed,may be involved in lung carcinoma

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003684 damaged DNA binding NAS9660799
GO:0005515 protein binding IPI10359610
GO:0008408 3'-5' exonuclease activity ISS--
GO:0008853 exodeoxyribonuclease III activity IEA--
GO:0016787 hydrolase activity IEA--
About this table

Pathways & Interactions
for RAD1

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Invitrogen iPath™ Online BioAtlas - Pathway for RAD1 (Maps provided by GeneGo):
 S-phase DNA damage response

   GeneDecks  RAD1 for the pathways selected above  
About GeneDecksing

 Gene Network CentralTM Interacting Genes and Proteins Network for  RAD1 


5/24 Interacting proteins for RAD1 (ENSP000003408793) via UniProtKB, MINT, and/or STRING (see all 24 )
InteractantInteraction Details
GeneCardExternal ID(s)
RAD17ENSP000003507253STRING (score=.999)
RAD9AENSP000003113603STRING (score=.999)
HUS1ENSP000002587743STRING (score=.973)
RAD9BENSP000003385703STRING (score=.96)
CHEK1ENSP000002789163STRING (score=.937)
About this table

5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO IDQualified GO termEvidencePubMed IDs
GO:0000075 cell cycle checkpoint NAS9660799
GO:0000077 DNA damage checkpoint TAS9716408
GO:0006260 DNA replication EXP12791985
GO:0006281 DNA repair TAS9872989
GO:0006974 response to DNA damage stimulus TAS9872989
About this table

Drugs & Compounds
for RAD1

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for RAD1

Transcripts
for RAD1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (RAD1)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (RAD1)
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 5): NR_026591

              Sigma-Aldrich siRNA and siRNA Panels for RAD1  
                     Sigma-Aldrich shRNA for RAD1  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_002853  NM_133377  

REFSEQ mRNAs for RAD1 gene (2 alternative transcripts): 

NM_002853.3   NM_133377.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_002853  NM_133377  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_002853
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_002853
                                 untagged cDNA clones in CMV expression vector (see all 6): BC009804 

Additional cDNA sequence: 

AF011905.1 AF030933.1 AF058392.1 AF058393.1 AF073524.1 AF074717.1 AF076841.1 AF084512.1 
AF084513.1 AF090170.1 AJ004974.1 AJ004975.1 AK002112.1 AK096960.1 AK125316.1 BC006837.1 
BC009804.1 BC035771.1 BC037857.1 BT006908.1 CR610090.1 

18 DOTS entries:

DT.444475  DT.100024236  DT.309747  DT.97841332  DT.99972608  DT.75103106  DT.100798519  DT.100798520 
DT.120802598  DT.425390  DT.100033743  DT.75114249  DT.92435047  DT.97764608  DT.100728535  DT.92044223 
DT.92430524  DT.95087434 

24/213 AceView cDNA sequences (see all 213 ):

BC037857 AI798551 D79907 AJ004974 AA525955 BQ771583 BM453151 BU682777 
AF076841 CF527867 BX479175 BM875344 AJ004975 AF058393 AF090170 CR610090 
BE738901 BX439078 BE379989 CD365064 N70774 AI245063 AU123712 AW779759 

highest scoring ESTs for RAD1:

AF030933 AF084513 AA029300 AA029857 AA227739 AA228124 AA367814 AA379231 AA421715 AA442431 

Unigene Cluster for RAD1:

RAD1 homolog (S. pombe)
Hs.38114  [show with all ESTs]
Unigene Representative Sequence: NM_002853


GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for RAD1

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
SP1:                    -     -                                             
SP2:                                                                        
SP3:              -     -     -     -     -                                 
SP4:                    -     -     -                                       
SP5:                                                                        

About this scheme

ECgene alternative splicing isoforms for RAD1

4 Ensembl transcripts including schematic representations:
ENST00000325577  ENST00000341754  ENST00000231383  ENST00000382038  

Expression
for RAD1

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

RAD1 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for RAD1

1 / 2 / 3

13 probe-sets matching RAD1 gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

90897_at2, 3 U95-E 1 1.00 1.00 0.82 1.23 AI742925 0.60 0.75 0.68 1

50930_at2, 3 U95-B 1 1.00 1.00 0.81 1.00 AI796010 0.60 1.00 0.82 1
36857_at2, 3 U95-A 3 1.00 0.84 0.79 0.78 AF084513 0.80 1.00 0.91 1

228535_at2, 3 U133-B 1 1.00 1.00 -- -- AI796010 0.60 1.00 0.82 1

235253_at2, 3 U133-B 1 1.00 1.00 -- -- AI742925 0.60 0.75 0.68 1

204461_x_at2, 3 U133-A 15 1.00 0.84 -- -- NM_002853 0.60 1.00 0.82 1

210216_x_at2, 3 U133-A 3 1.00 0.76 -- -- AF084513 0.80 1.00 0.91 1

204460_s_at2, 3 U133-A 3 1.00 0.70 -- -- AF074717 0.60 1.00 0.82 1

228535_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

235253_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

204461_x_at2 U133Plus2 15 1.00 0.84 -- -- -- -- -- -- --

210216_x_at2 U133Plus2 3 1.00 0.76 -- -- -- -- -- -- --

204460_s_at2 U133Plus2 3 1.00 0.70 -- -- -- -- -- -- --
GeneDecks  RAD1 for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: TAAATAAATG

SOURCE GeneReport for Unigene cluster: Hs.38114

Expression variation in blood from EXPOLDB for RAD1

UniProtKB/Swiss-Prot: RAD1_HUMAN, O60671
Tissue specificity: Expressed in testis, uterus, bladder, spleen, ovaries, lung, brain and muscle
(at protein level)

Orthologs
for RAD1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for RAD1 gene from 5/17 species (see all 17 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 RAD11   -- RAD1 homolog (S. pombe) 92.17(n)
95.73(a)		 479366  XM_536505.2  XP_536505.2 
chimpanzee
(Pan troglodytes)		 RAD11   -- RAD1 homolog (S. pombe) 99.88(n)
100(a)		 461928  XM_517813.2  XP_517813.2 
cow
(Bos taurus)		 RAD11   -- RAD1 homolog (S. pombe) 92.47(n)
96.42(a)		 518502  XM_596695.3  XP_596695.2 
rat
(Rattus norvegicus)		 Rad11   -- RAD1 homolog (S. pombe) 87.26(n)
90.36(a)		 294800  XM_215497.4  XP_215497.4 
mouse
(Mus musculus)		 Rad11, 5 155
 RAD1 homolog (S. pombe)1, 5 87.26(n)1
90.71(a)1		 193551  NM_011232.21  NP_035362.21 
 AA3869815  AA3874635  (see all 22)
About this table        Species with no ortholog for RAD1

ENSEMBL Gene Tree for RAD1

Paralogs
for RAD1

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Pseudogenes
2 related pseudogenes


SNPs/Variants
for RAD1

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/86 NCBI SNPs in RAD1 are shown (see all 86 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 55)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 5 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs18053271,2
C,F,H,O34944634(-) ATCTGA/GGTCTT 2 E/G mis1 ese315Minor allele frequency- C:0.00NA EU EA WA NS 2112
rs20694801,2
C,F,H34944514(-) CACAAT/CGGGGA 2 -- ut31 ese312Minor allele frequency- C:0.02NA EU EA WA NS 900
rs23089571,2
C,F,H34947641(-) CCAAGG/ATTATG 2 D/G mis15Minor allele frequency- A:0.01NA EU EA WA 1224
rs3424711,2
C,F,H34941169(+) GACAAG/TCAATG 2 -- ut318Minor allele frequency- T:0.00EA NA MN EU WA 652
rs47034841,2
A,C,F34942926(+) CAGGTA/GCTGAC 2 -- ut31 ese37Minor allele frequency- G:0.21NA NS 302
rs18053281,2
C,F,H34947671(-) AGGGAC/GTTTAA 2 T/S mis1 ese313Minor allele frequency- G:0.01NA EU EA WA 1960
rs20694821,2
F,H34943835(-) ggaggC/Gcagca 2 -- ut31 ese35Minor allele frequency- G:0.01NA EU EA WA 592
--
rs42822901,2
C,F34942300(+) GTTCAA/GGATTA 2 -- ut314Minor allele frequency- G:0.01NS 156
--
rs20694811,2
C,F34944122(-) ggaggC/Tggagg 2 -- ut31 ese35Minor allele frequency- T:0.21NA NS 334
--
rs115424491,2
C34944292(-) TGGGAA/GGCCGA 2 -- ut314Minor allele frequency- G:0.00NS 160
About this table

HapMap Linkage Disequilibrium images for RAD1 (up to first 250kb)

Disorders & Mutations
for RAD1

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 603153

Human Genome Epidemiology Navigator: RAD1 (52 documents)

Medical News
for RAD1

(Possibly Related Articles in Doctor's Guide)
About This Section

   --

Publications
for RAD1

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

10/56 PubMed articles for RAD1 gene (see all 56 ):

Search for RAD1

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing RAD1

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section
Entrez Gene: 5810 HGNC: 9806 AceView: RAD1 Ensembl:ENSG00000113456 euGenes: HUgn5810
ECgene: RAD1 H-InvDB: RAD1

Other Databases showing RAD1

(According to HUGE)
About This Section

   --

Specialized Databases showing RAD1

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
ATLAS Chromosomes in Cancer entry for RAD1 Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPshttp://egp.gs.washington.edu/data/rad1/

Licensable Technologies
for RAD1

(Available from WIS Yeda, Salk, Tufts)
About This Section

  --

Services
for RAD1

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for RAD1:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for RAD1-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for RAD1 Antibodies for RAD1
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for RAD1 Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
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 Recombinant & Natural Proteins  

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 Recombinant Proteins
(Rad1)
 Antibodies (Rad1)
 Tagged/untagged cDNA clones
 Validated SYBR primer pairs
 Purified proteins from HEK293T cells
 Western blot validated antibodies
 shRNA in GFP-retroviral vector
 Search Tocris compounds for RAD1




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 Antibodies for RAD1

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