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RABL6 Gene

protein-coding   GIFtS: 46
GCID: GC09P139702

RAB, Member RAS Oncogene Family-Like 6

(Previous name: chromosome 9 open reading frame 86)
(Previous symbol: C9orf86)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB, Member RAS Oncogene Family-Like 61 2     Chromosome 9 Open Reading Frame 861
C9orf861 2 3 5     pp88752
Partner Of ARF1 2 3     Putative GTP-Binding Protein Parf2
PARF2 3 5     Rab-Like GTP-Binding Protein 1C2
Rab-Like Protein 11 3     Rab-Like Protein 62
RBEL12 3     GTP-Binding Protein Parf3

External Ids:    HGNC: 247031   Entrez Gene: 556842   Ensembl: ENSG000001966427   OMIM: 6106155   UniProtKB: Q3YEC73   

Export aliases for RABL6 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RABL6 Gene:
This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP
and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer
tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of
chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this
gene. (provided by RefSeq, Dec 2011)

GeneCards Summary for RABL6 Gene:
RABL6 (RAB, member RAS oncogene family-like 6) is a protein-coding gene. Diseases associated with RABL6 include wiskott-aldrich syndrome, and breast cancer. GO annotations related to this gene include GTP binding.

UniProtKB/Swiss-Prot: RABL6_HUMAN, Q3YEC7
Function: May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A

Gene Wiki entry for RABL6 (C9orf86) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008470.20  
Regulatory elements:
   Search for regulatory transcription factor binding sites for RABL6
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RABL6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RABL6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

RABL6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RABL6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P139702:  view genomic region     (about GC identifiers)

Start:
139,702,374 bp from pter      End:
139,735,639 bp from pter
Size:
33,266 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RABL6_HUMAN, Q3YEC7 (See protein sequence)
Recommended Name: Rab-like protein 6  
Size: 729 amino acids; 79549 Da
Sequence caution: Sequence=AAH02945.2; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH21095.2; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH35786.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14408.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAB55213.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: A8QVZ7 A8QVZ8 C6K8I4 C6K8I5 Q4F968 Q5T5R7 Q8IWK1 Q8TCL4 Q8WU94 Q96SR8
Q9BU21 Q9H935
Alternative splicing: 6 isoforms:  Q3YEC7-1   Q3YEC7-2   Q3YEC7-3   Q3YEC7-4   Q3YEC7-5   Q3YEC7-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RABL6: NX_Q3YEC7

Explore proteomics data for RABL6 at MOPED

Post-translational modifications: 

  • Isoform 1 is O-glycosylated, while other isoforms are not1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RABL6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001167459.1  NP_001167460.1  NP_078994.3  

    ENSEMBL proteins: 
     ENSP00000433031   ENSP00000311134   ENSP00000350056   ENSP00000431675   ENSP00000412757  
     ENSP00000395490   ENSP00000408442   ENSP00000360727   ENSP00000360736   ENSP00000414081  
     ENSP00000360740  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR013684 MIRO-like
     IPR001806 Small_GTPase
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q3YEC7

    ProtoNet protein and cluster: Q3YEC7

    1 Blocks protein domain: IPB013684 Miro-like

    UniProtKB/Swiss-Prot: RABL6_HUMAN, Q3YEC7
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RABL6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RABL6_HUMAN, Q3YEC7
    Function: May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12646258
    GO:0005525GTP binding IEA--
         
    RABL6 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RABL6:
     Decreased Wnt reporter activit  Increased circadian period len  Large cells 

         1 MGI phenotypic allele for Rabl6 (no phenotypes)

    RABL6 for phenotypes           About GeneDecksing

    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RABL6_HUMAN, Q3YEC7: Isoform 1: Cytoplasm. Note=Predominantly cytoplasmic
    RABL6_HUMAN, Q3YEC7: Isoform 3: Nucleus. Note=Predominantly nuclear

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome ----

    RABL6 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RABL6
    Interactions:

        Search GeneGlobe Interaction Network for RABL6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RABL6 (Q3YEC71, 3 ENSP000003111344) via UniProtKB, MINT, STRING, and/or I2D (see all 56)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SPINK7P580621, 3, ENSP000002745654EBI-742029,EBI-1182445 I2D: score=4 STRING: ENSP00000274565
    MDFIQ997501, 3, ENSP000002303214EBI-742029,EBI-724076 I2D: score=4 STRING: ENSP00000230321
    RBPMSQ930623, ENSP000003401764I2D: score=4 STRING: ENSP00000340176
    C19orf57Q0VDD73, ENSP000002543364I2D: score=4 STRING: ENSP00000254336
    CALCOCO2Q131373, ENSP000002589474I2D: score=4 STRING: ENSP00000258947
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport ----

    RABL6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RABL6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RABL6 gene (4 alternative transcripts): 
    NM_001173988.1  NM_001173989.2  NM_024718.4  NM_017995.1  

    Unigene Cluster for RABL6:

    RAB, member RAS oncogene family-like 6
    Hs.370555  [show with all ESTs]
    Unigene Representative Sequence: AK128154
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000484471 ENST00000311502 ENST00000357466 ENST00000464941(uc004cjl.1)
    ENST00000436380(uc004cjm.2) ENST00000425121 ENST00000466096 ENST00000461992
    ENST00000435930(uc004cjn.1) ENST00000371663(uc004cjj.1 uc004cji.1 uc004cjk.1)
    ENST00000371671(uc004cjh.3) ENST00000432842 ENST00000371675(uc010nbs.1)

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    Additional mRNA sequence: 

    AK000963.1 AK001184.1 AK027586.1 AK128154.2 AK307431.1 AL713707.1 BC002945.2 BC018960.2 
    BC021095.1 BC024964.2 BC035786.1 DQ099383.1 DQ141240.1 EF156752.1 EF156753.1 GQ169126.1 

    21 DOTS entries:

    DT.412851  DT.95333024  DT.100845414  DT.100845412  DT.99949678  DT.121161411  DT.100031293  DT.100845408 
    DT.101968593  DT.121161436  DT.100031299  DT.95332993  DT.95333023  DT.100031300  DT.121161368  DT.86844151 
    DT.91763645  DT.95333013  DT.99945392  DT.100641616  DT.121161432 

    Selected AceView cDNA sequences (see all 671):

    BC007542 CA411626 BQ925352 AI951110 BM764553 AI524021 BU156593 CR613672 
    BG057020 BE793937 CA427785 CB528413 BU188402 AI239920 CA424742 NM_024718 
    BM711992 AA706997 BX387188 AI365637 AI337287 BQ651968 AI004172 BQ287917 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RABL6 (see all 17)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^
    SP1:              -     -     -                 -     -           -                             -                 -                                             
    SP2:                                            -     -           -                       -     -                                         -                     
    SP3:                                                                                                                                                        -   
    SP4:                                            -     -           -                             -                                                               
    SP5:                                                              -                             -                                                               

    ExUns: 18 ^ 19 ^ 20a · 20b · 20c ^ 21 ^ 22 ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c ^ 26 ^ 27 ^ 28a · 28b ^ 29 ^ 30a · 30b ^ 31 ^ 32a · 32b ^ 33
    SP1:                                                                                                                                                      
    SP2:                                                                                                                                                      
    SP3:  -     -     -     -                             -     -                       -     -                                                               
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for RABL6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RABL6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RABL6 Expression
    About this image


    RABL6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
    RABL6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RABL6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.370555
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RABL6 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rabl61 , 5 RIKEN cDNA B230208H17 gene5
    RAB, member of RAS oncogene family-like 61
    77.34(n)1
    78.51(a)1
      2 (17.46 cM)5
    2276241  NM_001024616.11  NP_001019787.21 
     255830185 
    chicken
    (Gallus gallus)
    Aves RABL61 RAB, member RAS oncogene family-like 6 69.95(n)
    70.63(a)
      417284  XM_003642269.2  XP_003642317.2 
    lizard
    (Anolis carolinensis)
    Reptilia RABL66
    RAB, member RAS oncogene family-like 6
    66(a)
    1 ↔ 1
    GL344343.1(14915-38282)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.87902 Xenopus laevis transcribed sequence with moderate similarity more 78.53(n)    AW159503.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-102c2.51 si:ch211-102c2.5 62.14(n)
    61.4(a)
      100003036  XM_001342645.5  XP_001342681.5 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0123481 AgaP_AGAP012348 60.37(n)
    52.22(a)
      1280358  XM_320205.2  XP_320205.2 
    worm
    (Caenorhabditis elegans)
    Secernentea F08G12.16
    Protein F08G12.1 (F08G12.1) mRNA, complete cds
    34(a)
    1 ↔ 1
    X(11302074-11305873) WBGene00008585


    ENSEMBL Gene Tree for RABL6 (if available)
    TreeFam Gene Tree for RABL6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RABL6 gene
    1 SIMAP similar gene for RABL6 using alignment to 7 protein entries:     RABL6_HUMAN (see all proteins):
    pp8875

    RABL6 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RABL6 (see all 6)
    PGOHUM00000234887 PGOHUM00000259254 PGOHUM00000240344 PGOHUM00000240345 PGOHUM00000249314


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RABL6 (see all 911)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2016438241,2
    C--109162556(+) GCCTTC/TTTTTT 3 -- int10--------
    rs341322641,2
    C--109168198(+) CATGGAT/-ATACT 3 -- int11Minor allele frequency- -:0.50CSA 2
    rs714832931,2
    C--109172117(+) AAAAAC/AAAAAA 3 -- int12Minor allele frequency- A:0.00NA 4
    rs112962421,2
    C--109176824(+) GTCTCA/-AAAAA 3 -- int1 trp31Minor allele frequency- -:0.00NA 2
    rs1137724111,2
    C--139708222(+) GTCACG/CACACC 3 -- int11Minor allele frequency- C:0.50CSA 2
    rs801687151,2
    C--139708937(+) GGATA-/AT/TA 
            
    CTAGT
    3 -- int10--------
    rs591373521,2
    C--139711598(+) AGCAG-/GAGAA 
     GCAGCAC
    GAGAA
    3 -- int10--------
    rs123434391,2
    C--139712685(+) tggcgA/Ggcgcc 3 -- int10--------
    rs714832941,2
    C--139712849(+) AAAAAC/AAAAAA 3 -- int12Minor allele frequency- A:0.00NA 4
    rs111458941,2
    C,A--139712857(+) AAAAAA/CCAAAG 3 -- int13Minor allele frequency- C:0.00NA CSA 5

    HapMap Linkage Disequilibrium report for RABL6 (139702374 - 139735639 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RABL6: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RABL6
    DNA2.0 Custom Variant and Variant Library Synthesis for RABL6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610615    OMIM disorders: --

    4 diseases for RABL6:    
    About MalaCards
    wiskott-aldrich syndrome    breast cancer    esophagitis    malaria


    RABL6 for disorders           About GeneDecksing


    Export disorders for RABL6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RABL6 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with RABL6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation. (PubMed id 19433581)1, 2, 3 Montalbano J.... Huang Y. (J. Biol. Chem. 2009)
    2. RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer. (PubMed id 17962191)1, 2, 3 Montalbano J.... Huang Y. (J. Biol. Chem. 2007)
    3. Identification of novel ARF binding proteins by two-hybrid screening. (PubMed id 16582619)1, 2, 3 Tompkins V.... Quelle D.E. (Cell Cycle 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Negative regulation of p53 by Ras superfamily protein RBEL1A. (PubMed id 23572512)1 Lui K....Huang Y. (J. Cell. Sci. 2013)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55684 HGNC: 24703 AceView: C9orf86andKIAA1984andMGC14141 Ensembl:ENSG00000196642 euGenes: HUgn55684
    ECgene: RABL6 H-InvDB: RABL6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RABL6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RABL6 gene:
    Search GeneIP for patents involving RABL6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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