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Aliases for RABL3 Gene

Aliases for RABL3 Gene

  • RAB, Member Of RAS Oncogene Family Like 3 2 3
  • RAB, Member Of RAS Oncogene Family-Like 3 2 5

External Ids for RABL3 Gene

Previous GeneCards Identifiers for RABL3 Gene

  • GC00U991171
  • GC03M121728
  • GC03M121726
  • GC03M121888
  • GC03M120405
  • GC03M117779

Summaries for RABL3 Gene

GeneCards Summary for RABL3 Gene

RABL3 (RAB, Member Of RAS Oncogene Family Like 3) is a Protein Coding gene. GO annotations related to this gene include GTP binding and GTPase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RABL3 Gene

Genomics for RABL3 Gene

Regulatory Elements for RABL3 Gene

Promoters for RABL3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RABL3 on UCSC Golden Path with GeneCards custom track

Genomic Location for RABL3 Gene

120,686,681 bp from pter
120,742,993 bp from pter
56,313 bases
Minus strand

Genomic View for RABL3 Gene

Genes around RABL3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RABL3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RABL3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RABL3 Gene

Proteins for RABL3 Gene

  • Protein details for RABL3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Rab-like protein 3
    Protein Accession:
    Secondary Accessions:
    • Q8WUD3

    Protein attributes for RABL3 Gene

    236 amino acids
    Molecular mass:
    26423 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RABL3 Gene

Proteomics data for RABL3 Gene at MOPED

Post-translational modifications for RABL3 Gene

  • Ubiquitination at Lys 231
  • Modification sites at PhosphoSitePlus

Other Protein References for RABL3 Gene

No data available for DME Specific Peptides for RABL3 Gene

Domains & Families for RABL3 Gene

Gene Families for RABL3 Gene

Protein Domains for RABL3 Gene


Suggested Antigen Peptide Sequences for RABL3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the small GTPase superfamily. Rab family.
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RABL3: view

Function for RABL3 Gene

genes like me logo Genes that share phenotypes with RABL3: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RABL3 Gene

Localization for RABL3 Gene

Subcellular locations from

Jensen Localization Image for RABL3 Gene COMPARTMENTS Subcellular localization image for RABL3 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RABL3 Gene

Pathways & Interactions for RABL3 Gene

SuperPathways for RABL3 Gene

No Data Available

Interacting Proteins for RABL3 Gene

Gene Ontology (GO) - Biological Process for RABL3 Gene


No data available for Pathways by source and SIGNOR curated interactions for RABL3 Gene

Drugs & Compounds for RABL3 Gene

No Compound Related Data Available

Transcripts for RABL3 Gene

Unigene Clusters for RABL3 Gene

RAB, member of RAS oncogene family-like 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RABL3 Gene

No ASD Table

Relevant External Links for RABL3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RABL3 Gene

mRNA expression in normal human tissues for RABL3 Gene

Protein differential expression in normal tissues from HIPED for RABL3 Gene

This gene is overexpressed in Bone (41.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RABL3 Gene

SOURCE GeneReport for Unigene cluster for RABL3 Gene Hs.444360

genes like me logo Genes that share expression patterns with RABL3: view

Protein tissue co-expression partners for RABL3 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RABL3 Gene

Orthologs for RABL3 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for RABL3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RABL3 35
  • 93.64 (n)
  • 97.03 (a)
RABL3 36
  • 96 (a)
(Canis familiaris)
Mammalia RABL3 35
  • 94.63 (n)
  • 97.88 (a)
RABL3 36
  • 88 (a)
(Mus musculus)
Mammalia Rabl3 35
  • 89.12 (n)
  • 92.37 (a)
Rabl3 16
Rabl3 36
  • 92 (a)
(Pan troglodytes)
Mammalia RABL3 35
  • 99.44 (n)
  • 100 (a)
RABL3 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Rabl3 35
  • 87.85 (n)
  • 92.37 (a)
(Monodelphis domestica)
Mammalia RABL3 36
  • 91 (a)
(Ornithorhynchus anatinus)
Mammalia RABL3 36
  • 90 (a)
(Gallus gallus)
Aves RABL3 35
  • 81.36 (n)
  • 92.89 (a)
RABL3 36
  • 93 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 70 (a)
-- 36
  • 86 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rabl3 35
  • 74.04 (n)
  • 91.06 (a)
Str.13474 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.15449 35
(Danio rerio)
Actinopterygii Dr.27288 35
rabl3 35
  • 73.53 (n)
  • 84.55 (a)
rabl3 36
  • 85 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13370 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006354 35
  • 57.19 (n)
  • 57.84 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4789 35
  • 50.59 (n)
  • 50.44 (a)
CG15399 36
  • 26 (a)
CG4789 36
  • 39 (a)
(Caenorhabditis elegans)
Secernentea CELE_Y116A8C.10 35
  • 44.61 (n)
  • 37.37 (a)
Y116A8C.10 36
  • 30 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G09910 35
  • 46.7 (n)
  • 35.94 (a)
(Oryza sativa)
Liliopsida Os10g0135200 35
  • 45.53 (n)
  • 38.14 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4393 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.610 36
  • 46 (a)
Species with no ortholog for RABL3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RABL3 Gene

Gene Tree for RABL3 (if available)
Gene Tree for RABL3 (if available)

Paralogs for RABL3 Gene

(1) SIMAP similar genes for RABL3 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with RABL3: view

No data available for Paralogs for RABL3 Gene

Variants for RABL3 Gene

Sequence variations from dbSNP and Humsavar for RABL3 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1062355 -- 120,688,250(-) GGGAA(G/T)TAGAA utr-variant-3-prime
rs1862935 -- 120,686,613(-) TCTCC(A/G)CTACA downstream-variant-500B
rs2008682 -- 120,716,553(-) TACAT(C/G)TGCCA intron-variant
rs2059331 -- 120,689,243(-) AATGG(C/G)TCAGT utr-variant-3-prime
rs2288096 -- 120,690,679(-) GGCAG(A/G)CTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RABL3 Gene

Variant ID Type Subtype PubMed ID
nsv877377 CNV Gain 21882294
nsv829699 CNV Loss 17160897
nsv877378 CNV Gain 21882294
esv272448 CNV Insertion 20981092
esv271232 CNV Insertion 20981092
esv1608308 CNV Insertion 17803354

Variation tolerance for RABL3 Gene

Residual Variation Intolerance Score: 31.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.67; 14.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RABL3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RABL3 Gene

Disorders for RABL3 Gene

Relevant External Links for RABL3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RABL3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RABL3 Gene

Publications for RABL3 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Evaluation of the novel gene Rabl3 in the regulation of proliferation and motility in human cancer cells. (PMID: 20596630) Li Q. … Wang L. (Oncol. Rep. 2010) 3

Products for RABL3 Gene

Sources for RABL3 Gene

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