RABGGTB Gene
protein-coding GIFtS: 55
GCID: GC01P076251
|
|
Rab geranylgeranyltransferase, beta subunit
| |
Aliases
for RABGGTB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rab Geranylgeranyltransferase, Beta Subunit1 2 | | EC 2.5.1.603 8 | | Rab GG Transferase Beta2 3 | | Geranylgeranyl Transferase Type-2 Subunit Beta2 | | Rab GGTase Beta2 3 | | Geranylgeranyl Transferase Type II Subunit Beta3 | | Type II Protein Geranyl-Geranyltransferase Subunit Beta2 3 | | Rab Geranyl-Geranyltransferase Subunit Beta3 | | GGTB2 3 | | Rab Geranylgeranyltransferase Subunit Beta3 | | GGTase-II-Beta1 | | |
Export aliases for RABGGTB gene to outside databasesPrevious GC identifers: GC01P076371 GC01P075186 GC01P075667 GC01P075674 GC01P075963 GC01P076024 GC01P074381 |
Summaries
for RABGGTB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RABGGTB:
This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to theprotein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups toC-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions ofthis gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with thisgene is located on chromosome 3. (provided by RefSeq, Jan 2013)
UniProtKB/Swiss-Prot: PGTB2_HUMAN, P53611Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines inRab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively
|
Genomic Views
for RABGGTB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RABGGTB gene promoter:
AP-4 E4BP4 Evi-1 C/EBPalpha POU2F1 GATA-6 POU2F1a FOXJ2 (long isoform) FOXJ2 LyF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RABGGTB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RABGGTB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p31 Ensembl cytogenetic band: 1p31.1 HGNC cytogenetic band: 1p31RABGGTB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P076251: view genomic region
(about GC identifiers)
Start:
|
76,251,879 bp from pter |
End:
|
76,260,764 bp from pter |
Size:
|
8,886 bases |
Orientation:
|
plus strand |
|
Proteins
for RABGGTB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PGTB2_HUMAN, P53611 (See
protein sequence)Recommended Name: Geranylgeranyl transferase type-2 subunit beta Size: 331 amino acids; 36924 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subunit: Heterodimer of an alpha and a beta subunit, collectively called component B. The Rab GGTase dimer (RGGT) canassociate with CHM (component A) prior to Rab protein binding; the association is stabilized by geranylgeranylpyrophosphate (GGpp). The CHM:RGGT:Rab complex is destabilized by GGpp. Interaction of beta subunit with prenylatedPTP4A2 precludes its association with subunit alpha, and inhibits enzyme activity
Secondary accessions: Q92697Explore the universe of human proteins at neXtProt for RABGGTB: NX_P53611
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P53611
4/6 DME Specific Peptides for RABGGTB (P53611) (see all 6)
RABGGTB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004573.2
ENSEMBL proteins: ENSP00000317473 ENSP00000359862 ENSP00000440452
Human Recombinant Protein Products:
RABGGTB Antibody Products:
Assay Products for RABGGTB: |
Protein
Domains /
Families
for RABGGTB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RABGGTB for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P53611ProtoNet protein and cluster: P53611 1 Blocks protein family: IPB001330 Prenyltransferase/squalene oxidase
UniProtKB/Swiss-Prot: PGTB2_HUMAN, P53611Similarity: Belongs to the protein prenyltransferase subunit beta familySimilarity: Contains 6 PFTB repeats |
Function
for RABGGTB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PGTB2_HUMAN, P53611Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines inRab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectivelyCatalytic activity: Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphateEnzyme regulation: The enzymatic reaction requires the aid of a Rab escort protein (also called component A) Genatlas biochemistry entry for RABGGTB:Rab geranyl-geranyltransferase B,type II,beta subunit
Enzyme Number (IUBMB): EC 2.5.1.601 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RABGGTB (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RABGGTB
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RABGGTB (NM_004582) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RABGGTB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RABGGTB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RABGGTB |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RABGGTB for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for RABGGTB:
Animal Models:
Mouse knock-out Rabggtbtm1Lex for RABGGTB
1 MGI phenotypic allele  for Rabggtb (no phenotypes)
RABGGTB for phenotypes About GeneDecksing
|
Pathways & Interactions
for RABGGTB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling events mediated by PRL | |
1  BioSystems Pathway for RABGGTB
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RABGGTB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/40 Interacting proteins for RABGGTB (P536111, 2, 3 ENSP000003174734) via UniProtKB, MINT, STRING, and/or I2D (see all 40)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
RABGGTB for ontologies About GeneDecksing
|
Drugs & Compounds
for RABGGTB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RABGGTB
4 DrugBank Compounds for RABGGTB About this table
Search CenterWatch for drugs/clinical trials and news about RABGGTB / PGTB2
|
Transcripts
for RABGGTB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RABGGTB gene: NM_004582.3 Unigene Cluster for RABGGTB: Rab geranylgeranyltransferase, beta subunit Hs.78948 [show with all ESTs]Unigene Representative Sequence: AB20902315 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000496055 ENST00000319942(uc001dgy.1 uc009wbt.1 uc001dhc.1)
ENST00000473406 ENST00000485459 ENST00000370826 ENST00000497648 ENST00000462042
ENST00000470201 ENST00000471759 ENST00000491266 ENST00000461653 ENST00000489450
ENST00000467748 ENST00000459697 ENST00000535300
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RABGGTB (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RABGGTB
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RABGGTB (NM_004582) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RABGGTB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RABGGTB |
Additional cDNA sequence: AB209023.1 AK127197.1 AK128861.1 AK293057.1 BC020790.1 BC035873.1 CR456941.1 U49245.1 X98001.1 Y08201.1 22 DOTS entries: DT.102832090 DT.449019 DT.95208188 DT.101984375 DT.92443127 DT.99992446 DT.100029891 DT.102832089 DT.92443131 DT.97847166 DT.40121418 DT.100797567 DT.97847169 DT.100797568 DT.102832088 DT.91725981 DT.100826150 DT.121438470 DT.92443137 DT.95331595 DT.97847167 DT.451554 24/344 AceView cDNA sequences (see all 344): R38066 BE349463 AI306733 BM555052 AA937894 AL702673 AA970379 AI298550 BM456849 F13029 AA767717 AA427560 AL552269 BI755898 AL707762 BC020790 CA390791 BU751998 BF511377 BQ003690 BM709893 BQ446510 CB130720 AK127197
GeneLoc Exon Structure
5/23 Alternative Splicing Database (ASD) splice patterns (SP) for RABGGTB (see all 23) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | | | | | | | | | - | | | | | | - | | | | | | - | | - | | - | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | | | - | | - | | - | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | | | - | | | | | | - | | | | | | - | | - | | - | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | - | | | | | | - | | - | | - | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | |
| ExUns: | 10c | · | 10d | · | 10e | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b | ^ | 13a | · | 13b | · | 13c | · | 13d |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | - | | - | | | | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | - | | | | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for RABGGTB
|
Expression
for RABGGTB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RABGGTB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See RABGGTB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RABGGTB
SOURCE GeneReport for Unigene cluster: Hs.78948
SABiosciences Custom PCR Arrays for RABGGTB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RABGGTB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RABGGTB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RABGGTB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RABGGTB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RABGGTB |
Orthologs
for RABGGTB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RABGGTB gene from 9/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RABGGTB1 |
Rab geranylgeranyltransferase, beta subunit |
80.56(n)
91.24(a) |
|
424723 XM_422548.3 XP_422548.2 |
lizard
(Anolis carolinensis) |
Reptilia |
RABGGTB6 |
-- |
88(a) |
1 ↔ 1 |
GL343194.1(3342089-3350409) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.48482 |
Transcribed sequence with moderate similarity to protein more |
80.45(n) |
|
142026521 |
zebrafish
(Danio rerio) |
Actinopterygii |
BC049442.12 |
-- |
75.77(n) |
|
BC049442.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
&bgr;ggt-II3
betaggt-II1 |
CAAX-protein geranylgeranyltransferase3
beta subunit of type II geranylgeranyl transferase1 |
64(a)3
58.14(n)1
65.05(a)1 |
|
23B73
477571 NM_080155.21 NP_524894.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
B0280.1b3
ggtb-11 |
Protein GGTB-11 |
55(a)
(best of 2)3
57.7(n)1
55.7(a)1 |
|
III(7205630-7207637)3
1759981 NM_066158.51 NP_498559.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
BET2(YPR176C)4
BET21 |
Beta subunit of Type II geranylgeranyltransferase required more4
Bet2p1 |
55.52(n)1
53.38(a)1 |
|
16(892078-891101)4
8563061, 4 NP_015502.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
RGTB11 |
RAB geranylgeranyl transferase beta subunit 1 |
59.15(n)
58.5(a) |
|
831094 NM_121259.3 NP_568259.1 |
rice
(Oryza sativa) |
Liliopsida |
AK102273.12 |
-- |
75.97(n) |
|
AK102273.1 |
ENSEMBL Gene Tree for RABGGTB (if available)
TreeFam Gene Tree for RABGGTB (if available) |
Paralogs
for RABGGTB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RABGGTB gene
- PGGT1B2
1 SIMAP similar gene for RABGGTB using alignment to 4 protein entries: PGTB2_HUMAN (see all proteins):CHURC1-FNTB
RABGGTB for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for RABGGTB
PGOHUM00000238134 PGOHUM00000259864
|
Genomic Variants
for RABGGTB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RABGGTB (76251879 - 76260764 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for RABGGTB: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RABGGTB |
|
Disorders
/ Diseases
for RABGGTB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RABGGTB for disorders About GeneDecksing
OMIM gene information: 179080
OMIM disorders: --
7  diseases for RABGGTB: About MalaCardschoroideremia retinal degeneration retinitis colorectal cancer
melanoma malaria choroiditis
Human Genome Epidemiology (HuGE) Navigator: RABGGTB (1 document)
Export disorders for RABGGTB gene to outside databases
|
Publications
for RABGGTB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RABGGTB gene, integrated from 9 sources (see all 39):
(articles sorted by number of sources associating them with RABGGTB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- cDNA cloning and chromosomal localization of the genes encoding the alpha- and beta-subunits of human Rab geranylgeranyl transferase: the 3' end of the alpha-subunit gene overlaps with the transglutaminase 1 gene promoter. (PubMed id 8954794)1, 2, 3 van Bokhoven H....Seabra M.C. (1996)
- Characterization of the interaction of the monomeric GTP-binding protein Rab3a with geranylgeranyl transferase II. (PubMed id 8706741)1, 2, 3 Johannes L.... Darchen F. (1996)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Interaction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase II. (PubMed id 11447212)1, 2 Si X.... Pallen C.J. (2001)
- Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A. (PubMed id 7991565)1, 2 Farnsworth C.C.... Glomset J.A. (1994)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Regulation of I^2-adrenergic receptor maturation and a nterograde trafficking by an interaction with Rab geranylgeranyltransferase: mo dulation of Rab geranylgeranylation by the receptor. (PubMed id 21990357)1 Lachance V....Parent J.L. (2011)
|
External Searches for RABGGTB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RABGGTB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RABGGTB gene
(According to HUGE)
About This Section
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Specialized Databases showing RABGGTB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for RABGGTB | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Rab_geranylgeranyltransferase |
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About This Section
| Patent Information for RABGGTB gene:
Search GeneIP for patents involving RABGGTB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RABGGTB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RABGGTB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RABGGTB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RABGGTB | | | OriGene Protein Over-expression Lysate for RABGGTB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RABGGTB | | OriGene 3'-UTR Clone for RABGGTB | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RABGGTB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RABGGTB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RABGGTB | | OriGene Custom Protein Services for RABGGTB | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RABGGTB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RABGGTB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RABGGTB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RABGGTB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RABGGTB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RABGGTB |
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| | | | Search Tocris compounds for RABGGTB |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RABGGTB |
|  |  |  | | | | Search ThermoFisher Antibodies for RABGGTB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RABGGTB |
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