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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RABGGTA Gene

protein-coding   GIFtS: 56
GCID: GC14M024734

Rab geranylgeranyltransferase, alpha subunit

 Explore 7 diseases affiliated with
RABGGTA via our new
 Human Malady Compendium 
Biological research products
for RABGGTA
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Rab Geranylgeranyltransferase, Alpha Subunit1 2     Rab GGTase Alpha2 3
PTAR31 2     EC 2.5.1.603 8
Geranylgeranyl Transferase Type II Subunit Alpha2 3     Geranylgeranyl Transferase Type-2 Subunit Alpha2
Rab Geranyl-Geranyltransferase Subunit Alpha2 3     Protein Prenyltransferase Alpha Subunit Repeat Containing 32
Rab GG Transferase Alpha2 3     Rab Geranylgeranyltransferase Subunit Alpha3

External Ids:    HGNC: 97951   Entrez Gene: 58752   Ensembl: ENSG000001009497   OMIM: 6019055   UniProtKB: Q926963   

Export aliases for RABGGTA gene to outside databases

Previous GC identifers: GC14M022107 GC14M018522 GC14M022724 GC14M023804 GC14M004849


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PGTA_HUMAN, Q92696
Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in
Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RABGGTA gene promoter:
         Sp1   STAT3   CUTL1   NF-kappaB   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRABGGTA promoter sequence
   Search SABiosciences Chromatin IP Primers for RABGGTA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RABGGTA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q11.2

RABGGTA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RABGGTA gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M024734:  view genomic region     (about GC identifiers)

Start:
24,734,744 bp from pter      End:
24,740,945 bp from pter
Size:
6,202 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PGTA_HUMAN, Q92696 (See protein sequence)
Recommended Name: Geranylgeranyl transferase type-2 subunit alpha  
Size: 567 amino acids; 65072 Da
Cofactor: Binds 1 zinc ion per dimer (By similarity)
Subunit: Heterodimer of an alpha and a beta subunit, collectively called component B. The Rab GGTase dimer (RGGT) can
associate with CHM (component A) prior to Rab protein binding; the association is stabilized by geranylgeranyl
pyrophosphate (GGpp). The CHM:RGGT:Rab complex is destabilized by GGpp
Secondary accessions: A8K5N2 D3DS69

Explore the universe of human proteins at neXtProt for RABGGTA: NX_Q92696

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q92696

  • 4/7 DME Specific Peptides for RABGGTA (Q92696) (see all 7)
     GRNRPSH  QKSPEELA  QKECVLLK  LPQHTFRVIWT 

    RABGGTA Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_004572.3  NP_878256.1  

    ENSEMBL proteins: 
     ENSP00000453596   ENSP00000382341   ENSP00000216840   ENSP00000453001   ENSP00000453890  
     ENSP00000453207   ENSP00000453201   ENSP00000452890  

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    Novus Biologicals RABGGTA Protein
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    Browse Proteins at Uscn


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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RABGGTA for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001611 Leu-rich_rpt
     IPR002088 Prenyl_trans_a
     IPR009087 RabGGT_asu_insert-domain

    Graphical View of Domain Structure for InterPro Entry Q92696

    ProtoNet protein and cluster: Q92696

    2 Blocks protein families:
    IPB001611 Leucine-rich repeat signature
    IPB009087 Rab geranylgeranyltransferase


    UniProtKB/Swiss-Prot: PGTA_HUMAN, Q92696
    Similarity: Belongs to the protein prenyltransferase subunit alpha family
    Similarity: Contains 5 LRR (leucine-rich) repeats
    Similarity: Contains 6 PFTA repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PGTA_HUMAN, Q92696
    Function: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in
    Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively
    Catalytic activity: Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate
    Enzyme regulation: The enzymatic reaction requires the aid of a Rab escort protein (also called component A)

         Genatlas biochemistry entry for RABGGTA:
    Rab geranyl-geranyltransferase B,type II,alpha subunit,2 kb upstream TGM1 (see symbol) in a head-to-head
    orientation,but not co-regulated in the terminal differentiation program of epidermal keratinocytes

    Enzyme Number (IUBMB): EC 2.5.1.601 2

    miRNA
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004663Rab geranylgeranyltransferase activity IEA--
    GO:0008270zinc ion binding IEA--
    GO:0008318protein prenyltransferase activity ----


    RABGGTA for ontologies           About GeneDecksing


    Animal Models:
         8 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rabggta):
     cellular  hematopoietic system  homeostasis/metabolism  immune system  integument 
     mortality/aging  pigmentation  reproductive system 

    RABGGTA for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Signaling events mediated by PRL
    Signaling events mediated by PRL1.00


    1 BioSystems Pathway for RABGGTA 
        Signaling events mediated by PRL


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RABGGTA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for RABGGTA (Q926963 ENSP000002168404) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RABGGTBP536113, ENSP000003174734I2D: score=6 STRING: ENSP00000317473
    CHMP243863, ENSP000003503864I2D: score=1 STRING: ENSP00000350386
    BMPR2Q138733, ENSP000003637084I2D: score=2 STRING: ENSP00000363708
    RAB1AP628203, ENSP000003872864I2D: score=2 STRING: ENSP00000387286
    C12orf4Q9NQ893I2D: score=5 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006464cellular protein modification process TAS8380507
    GO:0007601visual perception TAS8380507
    GO:0018342protein prenylation ----
    GO:0018344protein geranylgeranylation IEA--


    RABGGTA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for RABGGTA:
    Small Molecule - inhibitor
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    4 DrugBank Compounds for RABGGTA    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    FARNESYL-- --target--10592235
    FARNESYL DIPHOSPHATE-- --target--10592235
    GERANYLGERANYL DIPHOSPHATE-- --target--10592235
    N-Formylmethionine-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about RABGGTA / PGTA 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RABGGTA gene (2 alternative transcripts): 
    NM_004581.5  NM_182836.2  

    Unigene Cluster for RABGGTA:

    Rab geranylgeranyltransferase, alpha subunit
    Hs.377992  [show with all ESTs]
    Unigene Representative Sequence: NM_004581
    18/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000561055 ENST00000560521 ENST00000399409(uc001wof.3) ENST00000216840(uc001wog.3)
    ENST00000560243 ENST00000559551 ENST00000559974 ENST00000558376 ENST00000560777
    ENST00000560998 ENST00000558649 ENST00000559850 ENST00000560871 ENST00000543002
    ENST00000558534 ENST00000558936 ENST00000559586 ENST00000560127

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    Inhib. RNA
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RABGGTA
    Clone
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    Additional cDNA sequence: 

    AK291347.1 AK292613.1 BC003093.1 CR541797.1 Y08200.1 

    24/29 DOTS entries (see all 29):

    DT.453156  DT.100857644  DT.100857647  DT.100857658  DT.95132263  DT.120794919  DT.100759641  DT.100857645 
    DT.101969573  DT.95132254  DT.95132264  DT.100857666  DT.95132261  DT.100857642  DT.100857648  DT.100857663 
    DT.91764236  DT.100857655  DT.91764234  DT.100691784  DT.100758057  DT.100839272  DT.100857650  DT.100857665 

    24/241 AceView cDNA sequences (see all 241):

    CF131477 BQ446009 AI831864 CB528918 BU625339 CR606499 F01909 AU125148 
    CB112487 CR616135 BU727251 BM983576 CR608965 BX449847 BM754330 CA495381 
    BG117978 BQ071802 NM_004581 AW952228 BI523787 CR612475 BI753321 CR621196 

    GeneLoc Exon Structure

    5/17 Alternative Splicing Database (ASD) splice patterns (SP) for RABGGTA (see all 17)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d · 6e ^ 7a · 7b ^
    SP1:                                      -     -                 -                                                                                   -     -   
    SP2:                                                              -                                                                                   -     -   
    SP3:                                                                                                                                                  -     -   
    SP4:                                      -     -                 -                                                     -     -     -     -                     
    SP5:                                                                                                                                                            

    ExUns: 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b · 16c ^ 17 ^ 18
    SP1:                                            -                                         -               
    SP2:                                            -                                         -               
    SP3:                                            -                                                         
    SP4:                                                                                                      
    SP5:                                            -                                                         


    ECgene alternative splicing isoforms for RABGGTA

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RABGGTA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGGGCAGCGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RABGGTA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RABGGTA

    SOURCE GeneReport for Unigene cluster: Hs.377992
        SABiosciences Custom PCR Arrays for RABGGTA
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RABGGTA gene from 7/28 species (see all 28)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia RABGGTA6
    --
    48(a)
    1 ↔ 1
    GL343400.1(204844-218391)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia CF222571.12   -- 72.42(n)    CF222571.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rabggta1 Rab geranylgeranyltransferase, alpha subunit 62.58(n)
    58.08(a)
      767725  NM_001076663.1  NP_001070131.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG120071 , 3 RAB-protein geranylgeranyltransferase3
    CG120071
    37(a)3
    50.91(n)1
    41.61(a)1
      82F13
    406171  NM_141255.21  NP_649512.11 
    worm
    (Caenorhabditis elegans)
    Secernentea M57.21 , 3 Protein M57.21 30(a)3
    43.3(n)1
    33.58(a)1
      IV(3527360-3532268)3
    1771131  NM_067966.31  NP_500367.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RGTA16
    RGTA26
    RAB geranylgeranyl transferase alpha subunit 2
    22(a)
    20(a)
    1 ↔ many
    1 ↔ many
    4(12655059-12658336)
    5(16740804-16743433)
    rice
    (Oryza sativa)
    Liliopsida Os06g06775001 hypothetical protein 43.94(n)
    35.79(a)
      4341838  NM_001064892.1  NP_001058357.1 


    ENSEMBL Gene Tree for RABGGTA (if available)
    TreeFam Gene Tree for RABGGTA (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/156 NCBI SNPs in RABGGTA are shown (see all 156    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs80147521,2
    C,F,--4849501(+) CCTGGG/CAACGT 1 -- us2k13Minor allele frequency- C:0.18WA 122
    rs1837322011,2
    --24734268(+) TTCAAC/TCGTAG 3 -- us2k1 int10--------
    rs1895681271,2
    --24734295(+) ACCGAC/TAGTGT 3 -- us2k1 int10--------
    rs1439527141,2
    --24734422(+) GGGGTA/CATGGG 2 -- int10--------
    rs1472969651,2
    --24734536(+) CCAGTC/GCCAGC 2 -- int10--------
    rs1392930281,2
    --24734537(+) CAGTCC/TCAGCC 2 -- int10--------
    rs21801961,2
    C,F,A,H,--24734645(-) TTCTGC/TGCCAT 2 -- int112Minor allele frequency- T:0.13NS EA NA 1416
    rs1446459771,2
    C,--24734650(+) GCAGA-/AAGAAGGA 2 -- int10--------
    rs1862417661,2
    --24734676(+) CATGTC/GTCTTC 2 -- int10--------
    rs1430876881,2
    --24734761(+) GAGGGC/TCTCTC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for RABGGTA (24734744 - 24740945 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RABGGTA: --
    Human Gene Mutation Database (HGMD): RABGGTA

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RABGGTA for disorders           About GeneDecksing

    OMIM gene information: 601905    OMIM disorders: --

    7 diseases for RABGGTA:    About MalaCards
    hermansky-pudlak syndrome    choroideremia    retinal degeneration    retinitis
    colorectal cancer    malaria    choroiditis

    1 disease from the University of Copenhagen DISEASES database for RABGGTA:
    Hermansky-Pudlak syndrome

    Export disorders for RABGGTA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RABGGTA gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with RABGGTA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning and chromosomal localization of the genes encoding the alpha- and beta-subunits of human Rab geranylgeranyl transferase: the 3' end of the alpha-subunit gene overlaps with the transglutaminase 1 gene promoter. (PubMed id 8954794)1, 2, 3 van Bokhoven H....Seabra M.C. (1996)
    2. The genes encoding geranylgeranyl transferase alpha-subunit and transglutaminase 1 are very closely linked but not functionally related in terminally differentiating keratinocytes. (PubMed id 9196026)1, 2, 9 Song H.-J.... Steinert P.M. (1997)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A. (PubMed id 7991565)1, 2 Farnsworth C.C.... Glomset J.A. (1994)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Genetic variation in 3-hydroxy-3-methylglutaryl CoA r eductase modifies the chemopreventive activity of statins for colorectal cancer . (PubMed id 20403997)1 Lipkin S.M....Gruber S.B. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5875 HGNC: 9795 AceView: RABGGTA Ensembl:ENSG00000100949 euGenes: HUgn5875
    ECgene: RABGGTA H-InvDB: RABGGTA

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RABGGTA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RABGGTA gene:
    Search GeneIP for patents involving RABGGTA

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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