RABEP1 Gene
protein-coding GIFtS: 56
GCID: GC17P005185
|
|
rabaptin, RAB GTPase binding effector protein 1
| |
Aliases
for RABEP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Rabaptin, RAB GTPase Binding Effector Protein 11 2 | | Rabaptin-43 | | RABPT51 2 3 5 | | Rabaptin-5alpha3 | | RAB5EP1 2 3 | | RABPT5A3 | | Neurocrescin1 | | Rabaptin-43 | | Rabaptin-53 | | Rabaptin-53 | | Renal Carcinoma Antigen NY-REN-172 3 | | Rabaptin-5alpha3 | | Rab GTPase-Binding Effector Protein 12 | | |
Export aliases for RABEP1 gene to outside databasesPrevious GC identifers: GC17P005130 GC17P005386 GC17P005127 GC17P005076 |
Summaries
for RABEP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: RABE1_HUMAN, Q15276Function: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membranefusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A
Gene Wiki entry for RABEP1
|
Genomic Views
for RABEP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RABEP1 gene promoter:
c-Fos AP-1 MAZR Egr-1 GATA-2 GATA-1 Egr-2 HFH-1 STAT3 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for RABEP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RABEP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.2 Ensembl cytogenetic band: 17p13.2 HGNC cytogenetic band: 17p13.2RABEP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P005185: view genomic region
(about GC identifiers)
Start:
|
5,185,558 bp from pter |
End:
|
5,289,132 bp from pter |
Size:
|
103,575 bases |
Orientation:
|
plus strand |
|
Proteins
for RABEP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RABE1_HUMAN, Q15276 (See
protein sequence)Recommended Name: Rab GTPase-binding effector protein 1 Size: 862 amino acids; 99290 Da
Subunit: Homodimer when bound to RAB5A. Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have beenactivated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2. Interacts with ECM29
Subcellular location: Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle
2 PDB 3D structures from  and Proteopedia  for RABEP1:1TU3 (3D)
1X79 (3D)
Secondary accessions: B2RAG7 O95369 Q8IVX3Alternative splicing: 2 isoforms: Q15276-1 Q15276-2 Explore the universe of human proteins at neXtProt for RABEP1: NX_Q15276
Post-translational modifications:
Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15276
RABEP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001077054.1 NP_004694.2
ENSEMBL proteins: ENSP00000459550 ENSP00000437701 ENSP00000339569 ENSP00000460980 ENSP00000466981 ENSP00000262477 ENSP00000386150 ENSP00000445408
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
RABEP1 for ontologies About GeneDecksing
RABEP1 Antibody Products:
Assay Products for RABEP1: |
Protein
Domains /
Families
for RABEP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RABEP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15276ProtoNet protein and cluster: Q15276 1 Blocks protein family: IPB003914 Rabaptin signature
UniProtKB/Swiss-Prot: RABE1_HUMAN, Q15276Similarity: Belongs to the rabaptin family |
Function
for RABEP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RABE1_HUMAN, Q15276Function: Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membranefusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RABEP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RABEP1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RABEP1 (NM_004703) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RABEP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RABEP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RABEP1 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
RABEP1 for ontologies About GeneDecksing
Animal Models:
1 MGI phenotypic allele  for Rabep1 (no phenotypes)
RABEP1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for RABEP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Normal wtCFTR traffic / Sorting endosome formation | | | 2 | Endocytosis | | | 3 | wtCFTR and deltaF508 traffic / Membrane expression (norm and CF) | | | 4 | Clathrin-dependent protein traffic | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4  GeneGo (Thomson Reuters) Pathways for RABEP1
1 
Kegg Pathway (Kegg details for RABEP1):
RABEP1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RABEP1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/34 Interacting proteins for RABEP1 (Q152761, 2, 3 ENSP000002624774) via UniProtKB, MINT, STRING, and/or I2D (see all 34)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| GGA1 | Q9UJY51, 3, ENSP000003413444 | EBI-447043,EBI-447141 I2D:
score=4 STRING: ENSP00000341344 | | YWHAG | P619812, 3, ENSP000003063304 | MINT-50882 I2D:
score=4 STRING: ENSP00000306330 | | GGA2 | Q9UJY41, 2, 3, ENSP000003119624 | EBI-447043,EBI-447646 MINT-14026 I2D:
score=5 STRING: ENSP00000311962 | | AP1G1 | O437471, 3, ENSP000003771484 | EBI-447043,EBI-447609 I2D:
score=4 STRING: ENSP00000377148 | | GGA3 | Q9NZ521, 3, ENSP000002455414 | EBI-447043,EBI-447404 I2D:
score=4 STRING: ENSP00000245541 |
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
RABEP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for RABEP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RABEP1 for compounds About GeneDecksing
 Browse Tocris compounds for RABEP1
1 HMDB Compound for RABEP1 About this table
1 Novoseek chemical compound relationship for RABEP1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| gtp |
45.4 |
4 |
8521472 (2), 11718716 (1), 11309205 (1) |
Search CenterWatch for drugs/clinical trials and news about RABEP1 / RABE1
|
Transcripts
for RABEP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RABEP1 gene (2 alternative transcripts): NM_001083585.1 NM_004703.4 Unigene Cluster for RABEP1: Rabaptin, RAB GTPase binding effector protein 1 Hs.592121 [show with all ESTs]Unigene Representative Sequence: NM_00470310 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000575991 ENST00000546142 ENST00000575475(uc010cld.1) ENST00000341923
ENST00000570487 ENST00000574568 ENST00000572250 ENST00000262477(uc010vsw.1 uc002gbm.4)
ENST00000408982(uc002gbj.3 uc002gbk.2 uc010clc.1 uc002gbl.4)
ENST00000537505
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RABEP1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RABEP1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RABEP1 (NM_004703) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RABEP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RABEP1 |
Additional cDNA sequence: AF098638.1 AK297535.1 AK310932.1 AK314183.1 AL050211.1 AL157499.1 BC018742.1 BC032435.1 BC041700.1 BC065242.1 X77723.1 X91141.1 22 DOTS entries: DT.120977918 DT.100815238 DT.120977695 DT.119229 DT.100880026 DT.99939415 DT.120977833 DT.95290006 DT.91684931 DT.91771989 DT.40254712 DT.92392354 DT.86859353 DT.95173253 DT.100815240 DT.75166583 DT.91684928 DT.97856963 DT.40195405 DT.75121287 DT.91948510 DT.91948883 24/390 AceView cDNA sequences (see all 390): BM725683 CR624657 CA310624 AW008885 BE700072 BE378234 BC018742 AL118955 AI367258 AI888938 F07054 AA737336 AA764899 AI203116 BF434880 AI081498 CF144023 AW503197 BF111647 BM980069 BM722352 AA412174 BC032435 BX103338
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for RABEP1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b |
|---|
|
| SP1: | | | | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RABEP1
|
Expression
for RABEP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RABEP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCACTCAGT
About this image
See RABEP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RABEP1
SOURCE GeneReport for Unigene cluster: Hs.592121
SABiosciences Custom PCR Arrays for RABEP1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RABEP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RABEP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RABEP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RABEP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RABEP1 |
Orthologs
for RABEP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RABEP1 gene from 6/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RABEP11 |
rabaptin, RAB GTPase binding effector protein 1 |
79.96(n)
88.02(a) |
|
395930 NM_205057.1 NP_990388.1 |
lizard
(Anolis carolinensis) |
Reptilia |
RABEP16 |
-- |
83(a) |
1 ↔ 1 |
GL343613.1(343124-366638) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.324472 |
Xenopus laevis transcribed sequence with weak similarity more |
79.35(n) |
|
BJ644291.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
rabep11 |
rabaptin, RAB GTPase binding effector protein 1 |
66.34(n)
72.38(a) |
|
568064 NM_001123287.1 NP_001116759.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG40301 |
CG4030 |
41.23(n)
27.55(a) |
|
37395 NM_137701.2 NP_611545.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
rabn-51 |
Protein RABN-5 |
42.95(n)
30.87(a) |
|
175823 NM_065865.3 NP_498266.1 |
ENSEMBL Gene Tree for RABEP1 (if available)
TreeFam Gene Tree for RABEP1 (if available) |
Paralogs
for RABEP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RABEP1 gene
- RABEP22
RABEP1 for paralogs About GeneDecksing
|
Genomic Variants
for RABEP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RABEP1 (5185558 - 5289132 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RABEP1
1 Indel: 58801 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RABEP1 |
|
Disorders
/ Diseases
for RABEP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RABEP1 for disorders About GeneDecksing
OMIM gene information: 603616
OMIM disorders: --
15  diseases for RABEP1: About MalaCardsrenal carcinoma myelomonocytic leukemia carcinoma chronic myelomonocytic leukemia
multiple system atrophy macular degeneration tuberous sclerosis phenylketonuria
renal cell carcinoma alzheimer's disease down syndrome leukemia
ischemia ataxia neuronitis
2 Novoseek disease relationships for RABEP1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| alzheimers disease |
7.01 |
1 |
17961730 (1) |
| tumors |
0 |
1 |
11588050 (1) |
Export disorders for RABEP1 gene to outside databases
|
Publications
for RABEP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RABEP1 gene, integrated from 9 sources (see all 84):
(articles sorted by number of sources associating them with RABEP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion. (PubMed id 8521472)1, 2, 3, 9 Stenmark H.... Zerial M. (1995)
- Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex. (PubMed id 11452015)1, 2, 9 Lippe R.... Zerial M. (2001)
- Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex. (PubMed id 12505986)1, 2, 9 Mattera R.... Bonifacino J.S. (2003)
- A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. (PubMed id 20682791)1, 2 Gorbea C.... Rechsteiner M. (2010)
- Structural basis of Rab5-Rabaptin5 interaction in endocytosis. (PubMed id 15378032)1, 2 Zhu G.... Zhang X.C. (2004)
- Rabaptin4, a novel effector of the samll GTPase rab4a, is recruited to perinuclear recycling vesicles. (PubMed id 10698684)1, 2 Nagelkerken B.... van der Sluijs P. (2000)
- The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis. (PubMed id 9045618)1, 2 Xiao G.-H.... Yeung R.S. (1997)
- The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle. (PubMed id 14636058)1, 9 Zhai P....Zhang X.C. (2003)
- Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. (PubMed id 12773381)2, 9 Deneka M.... van der Sluijs P. (2003)
- Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5. (PubMed id 9524117)1, 9 Vitale G....Zerial M. (1998)
|
External Searches for RABEP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RABEP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RABEP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RABEP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RABEP1 gene:
Search GeneIP for patents involving RABEP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RABEP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RABEP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RABEP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RABEP1 | | | OriGene Protein Over-expression Lysate for RABEP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RABEP1 | | OriGene 3'-UTR Clone for RABEP1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RABEP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RABEP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RABEP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RABEP1 | | OriGene Custom Protein Services for RABEP1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RABEP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RABEP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RABEP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RABEP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RABEP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RABEP1 |
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| | | | Search Tocris compounds for RABEP1 |
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 | | | RABEP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RABEP1 |
|  |  |  | | | | Search ThermoFisher Antibodies for RABEP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RABEP1 |
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