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Aliases for RAB9B Gene

Aliases for RAB9B Gene

  • RAB9B, Member RAS Oncogene Family 2 3
  • RAB9L 3 4 6
  • Rab-9-Like Protein 3 4
  • Rab-9L 3 4
  • Ras-Related Protein Rab-9B 3
  • RAB9-Like Protein 3

External Ids for RAB9B Gene

Previous GeneCards Identifiers for RAB9B Gene

  • GC0XM098381
  • GC0XM099989
  • GC0XM101064
  • GC0XM101849
  • GC0XM102883
  • GC0XM102966
  • GC0XM103077
  • GC0XM092733

Summaries for RAB9B Gene

Entrez Gene Summary for RAB9B Gene

  • This gene encodes a member of a subfamily of RAS small guanosine triphosphate (GTP)-binding proteins that regulate membrane trafficking. The encoded protein may be involved in endosome-to-Golgi transport. [provided by RefSeq, Jan 2010]

GeneCards Summary for RAB9B Gene

RAB9B (RAB9B, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB9B include pelizaeus-merzbacher disease. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Influenza A. GO annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB9A.

UniProtKB/Swiss-Prot for RAB9B Gene

  • Involved in the transport of proteins between the endosomes and the trans Golgi network.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB9B Gene

Genomics for RAB9B Gene

Regulatory Elements for RAB9B Gene

Genomic Location for RAB9B Gene

103,822,322 bp from pter
103,919,275 bp from pter
96,954 bases
Minus strand

Genomic View for RAB9B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB9B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB9B Gene

Proteins for RAB9B Gene

  • Protein details for RAB9B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ras-related protein Rab-9B
    Protein Accession:
    Secondary Accessions:
    • B2R8M0
    • Q52LX2

    Protein attributes for RAB9B Gene

    201 amino acids
    Molecular mass:
    22719 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RAB9B Gene

neXtProt entry for RAB9B Gene

Proteomics data for RAB9B Gene at MOPED

Post-translational modifications for RAB9B Gene

  • Ubiquitination at Lys103
  • Modification sites at PhosphoSitePlus

Other Protein References for RAB9B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAB9B Gene

Domains for RAB9B Gene

Gene Families for RAB9B Gene

  • RAB :RAB, member RAS oncogene

Suggested Antigen Peptide Sequences for RAB9B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9NP90
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RAB9B: view

Function for RAB9B Gene

Molecular function for RAB9B Gene

UniProtKB/Swiss-Prot Function: Involved in the transport of proteins between the endosomes and the trans Golgi network.

Gene Ontology (GO) - Molecular Function for RAB9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity IBA --
GO:0005515 protein binding IPI 19490898
GO:0005525 GTP binding IEA --
GO:0019003 GDP binding IDA 20937701
genes like me logo Genes that share ontologies with RAB9B: view

Phenotypes for RAB9B Gene

GenomeRNAi human phenotypes for RAB9B:
genes like me logo Genes that share phenotypes with RAB9B: view

Animal Model Products

CRISPR Products

miRNA for RAB9B Gene

miRTarBase miRNAs that target RAB9B

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RAB9B

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RAB9B Gene

Localization for RAB9B Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB9B Gene

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.

Subcellular locations from

Jensen Localization Image for RAB9B Gene COMPARTMENTS Subcellular localization image for RAB9B gene
Compartment Confidence
plasma membrane 5
cytosol 3
extracellular 2
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for RAB9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005737 cytoplasm --
GO:0005764 lysosome IBA --
GO:0005770 late endosome IBA --
genes like me logo Genes that share ontologies with RAB9B: view

Pathways for RAB9B Gene

genes like me logo Genes that share pathways with RAB9B: view

Pathways by source for RAB9B Gene

1 Qiagen pathway for RAB9B Gene
1 KEGG pathway for RAB9B Gene

Gene Ontology (GO) - Biological Process for RAB9B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006184 obsolete GTP catabolic process --
GO:0006886 intracellular protein transport IBA --
GO:0006913 nucleocytoplasmic transport --
GO:0007165 signal transduction --
GO:0007264 small GTPase mediated signal transduction --
genes like me logo Genes that share ontologies with RAB9B: view

Transcripts for RAB9B Gene

mRNA/cDNA for RAB9B Gene

(76) Selected AceView cDNA sequences:
(6) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB9B Gene

RAB9B, member RAS oncogene family:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RAB9B

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RAB9B Gene

No ASD Table

Relevant External Links for RAB9B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB9B Gene

mRNA expression in normal human tissues for RAB9B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAB9B Gene

SOURCE GeneReport for Unigene cluster for RAB9B Gene Hs.522736

mRNA Expression by UniProt/SwissProt for RAB9B Gene

Tissue specificity: Ubiquitous.
genes like me logo Genes that share expressions with RAB9B: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for RAB9B Gene

Orthologs for RAB9B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RAB9B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RAB9B 35
  • 99.83 (n)
  • 100 (a)
RAB9B 36
  • 100 (a)
(Bos Taurus)
Mammalia RAB9B 35
  • 94.03 (n)
  • 99.5 (a)
RAB9B 36
  • 100 (a)
(Canis familiaris)
Mammalia RAB9B 35
  • 94.03 (n)
  • 99.5 (a)
RAB9B 36
  • 100 (a)
(Mus musculus)
Mammalia Rab9b 35
  • 92.04 (n)
  • 98.01 (a)
Rab9b 16
Rab9b 36
  • 98 (a)
(Monodelphis domestica)
Mammalia RAB9B 36
  • 95 (a)
(Ornithorhynchus anatinus)
Mammalia RAB9B 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Rab9b 35
  • 91.54 (n)
  • 98.51 (a)
(Gallus gallus)
Aves RAB9B 35
  • 80.76 (n)
  • 93.53 (a)
RAB9B 36
  • 87 (a)
(Anolis carolinensis)
Reptilia RAB9B 36
  • 86 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rab9b 35
  • 74.46 (n)
  • 85.07 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.1580 35
(Danio rerio)
Actinopterygii rab9b 35
  • 68.82 (n)
  • 77.61 (a)
rab9b 36
  • 77 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009846 35
  • 53.87 (n)
  • 56.06 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rab9 35
  • 56.63 (n)
  • 56.45 (a)
Rab9 36
  • 42 (a)
CG9994 37
  • 54 (a)
Rab7 37
  • 57 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YPT7 36
  • 46 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 58 (a)
Species with no ortholog for RAB9B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RAB9B Gene

Gene Tree for RAB9B (if available)
Gene Tree for RAB9B (if available)

Paralogs for RAB9B Gene

Paralogs for RAB9B Gene Pseudogenes for RAB9B Gene

genes like me logo Genes that share paralogs with RAB9B: view

Variants for RAB9B Gene

Sequence variations from dbSNP and Humsavar for RAB9B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs178301 -- 103,894,958(-) cacac(C/T)acacc intron-variant
rs178302 -- 103,894,876(-) aaact(A/G)tctct intron-variant
rs178303 -- 103,894,830(-) aagaa(A/T)ctcac intron-variant
rs178304 -- 103,892,669(-) attca(A/G)gatgg intron-variant
rs178305 -- 103,892,471(-) ccatc(A/G)gagtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RAB9B Gene

Variant ID Type Subtype PubMed ID
dgv2459e1 CNV Complex 17122850

Relevant External Links for RAB9B Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAB9B Gene

Disorders for RAB9B Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for RAB9B Gene including...

Search for RAB9B Gene in MalaCards »

(1) University of Copenhagen DISEASES for RAB9B Gene

genes like me logo Genes that share disorders with RAB9B: view

No data available for UniProtKB/Swiss-Prot for RAB9B Gene

Publications for RAB9B Gene

  1. cDNA cloning of a new member of the Ras superfamily, RAB9-like, on the human chromosome Xq22.1-q22.3 region. (PMID: 11043518) Seki N. … Saito T. (J. Hum. Genet. 2000) 2 3 4
  2. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (PMID: 21255211) Seto S. … Koide Y. (Traffic 2011) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus. (PMID: 16140752) Murray J.L. … Hodge T.W. (J. Virol. 2005) 3

Products for RAB9B Gene

  • Addgene plasmids for RAB9B

Sources for RAB9B Gene

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