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RAB9A Gene

protein-coding   GIFtS: 60
GCID: GC0XP013707

RAB9A, Member RAS Oncogene Family

(Previous names: RAB9, member RAS oncogene family)
(Previous symbol: RAB9)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB9A, Member RAS Oncogene Family1 2
RAB91 2 3 5
RAB9, Member RAS Oncogene Family1 2
Ras-Related Protein Rab-9A2

External Ids:    HGNC: 97921   Entrez Gene: 93672   Ensembl: ENSG000001235957   OMIM: 3002845   UniProtKB: P511513   

Export aliases for RAB9A gene to outside databases

Previous GC identifers: GC0XP012946 GC0XP012527 GC0XP013068 GC0XP013466 GC0XP013617 GC0XP011465


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB9A Gene:
RAB9A (RAB9A, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB9A include vaccinia, and niemann-pick disease. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RABL2B.

UniProtKB/Swiss-Prot: RAB9A_HUMAN, P51151
Function: Involved in the transport of proteins between the endosomes and the trans Golgi network

Gene Wiki entry for RAB9A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_167197.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB9A gene promoter:
         c-Fos   Bach1   AP-1   AML1a   Sp1   Fra-1   FosB   LCR-F1   AREB6   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB9A promoter sequence
   Search Chromatin IP Primers for RAB9A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB9A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.2   Ensembl cytogenetic band:  Xp22.2   HGNC cytogenetic band: Xp22.2

RAB9A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB9A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP013707:  view genomic region     (about GC identifiers)

Start:
13,707,240 bp from pter      End:
13,728,625 bp from pter
Size:
21,386 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RAB9A_HUMAN, P51151 (See protein sequence)
Recommended Name: Ras-related protein Rab-9A  
Size: 201 amino acids; 22838 Da
Subunit: Interacts (preferentially in its GTP-bound form) with GCC2 (via its GRIP domain)
1 PDB 3D structure from and Proteopedia for RAB9A:
1WMS (3D)    
Secondary accessions: A8K390 Q6ICN1

Explore the universe of human proteins at neXtProt for RAB9A: NX_P51151

Explore proteomics data for RAB9A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys103
  • Modification sites at PhosphoSitePlus

  • See RAB9A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001182257.1  NP_004242.1  

    ENSEMBL proteins: 
     ENSP00000420127  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry P51151

    ProtoNet protein and cluster: P51151

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB9A_HUMAN, P51151
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RAB9A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB9A_HUMAN, P51151
    Function: Involved in the transport of proteins between the endosomes and the trans Golgi network

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity IDA15263003
    GO:0005515protein binding IPI18243103
    GO:0005525GTP binding IDA15263003
    GO:0019003GDP binding IDA15263003
         
    RAB9A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RAB9A:
     Decreased viability with pacli  Elongated cells 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rab9):
     normal 

    RAB9A for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB9A
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    hsa-miR-3163 hsa-miR-136 hsa-miR-137 hsa-miR-15a hsa-miR-497 hsa-miR-519e* hsa-miR-515-5p hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidRAB9A 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB9A_HUMAN, P51151: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Endoplasmic reticulum membrane
    (Potential). Golgi apparatus membrane (Potential). Late endosome. Cytoplasmic vesicle, phagosome membrane;
    Lipid-anchor; Cytoplasmic side (By similarity). Cytoplasmic vesicle, phagosome. Note=Colocalizes with OSBPL1A at
    the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    lysosome5
    plasma membrane5
    vacuole5
    cytosol3
    endoplasmic reticulum3
    golgi apparatus3
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005764lysosome IDA15078902

    RAB9A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB9A About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Clathrin dependent protein traffic
    Clathrin dependent protein traffic0.66
    wtCFTR and delta508 CFTR traffic Generic schema norm and CF 0.37
    Transport Clathrin coated vesicle cycle0.66
    2Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36
    3Influenza A
    Measles0.34
    4wtCFTR and deltaF508 traffic Late endosome and Lysosome norm and CF
    wtCFTR and deltaF508 traffic Late endosome and Lysosome norm and CF
    5Cytoskeletal Signaling
    Cytoskeletal Signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB9A
        Epithelial Tight Junctions

    1 Cell Signaling Technology (CST) Pathway for RAB9A
        Cytoskeletal Signaling

    4 GeneGo (Thomson Reuters) Pathways for RAB9A
        wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
    Transport Clathrin-coated vesicle cycle
    wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)
    Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF)


    1 Kegg Pathway  (Kegg details for RAB9A):
        Measles


    RAB9A for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB9A
    Interactions:

        GeneGlobe Interaction Network for RAB9A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB9A (P511513 ENSP000004201274) via UniProtKB, MINT, STRING, and/or I2D (see all 68)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLIN3O606643, ENSP000002219574I2D: score=4 STRING: ENSP00000221957
    GDI1P311503, ENSP000003940714I2D: score=3 STRING: ENSP00000394071
    GDI2P503953, ENSP000003695384I2D: score=3 STRING: ENSP00000369538
    TM9SF2Q998053, ENSP000003655674I2D: score=2 STRING: ENSP00000365567
    BCL3P207493, ENSP000001642274I2D: score=2 STRING: ENSP00000164227
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS9126495
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    RAB9A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB9A

    2 DrugBank Compounds for RAB9A    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Benzoic Acid-- 65-85-0target--17139284 17016423
    Guanosine-5'-Diphosphate-- 146-91-8target--17139284 17016423

    4 Novoseek inferred chemical compound relationships for RAB9A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 6-phosphate 59.7 2 10821869 (2)
    gdp 46.5 2 15196914 (2)
    cholesterol 34.9 3 15972801 (1), 12576506 (1), 17213331 (1)
    lipid 6.54 7 18681838 (4)



    RAB9A for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAB9A gene (2 alternative transcripts): 
    NM_001195328.1  NM_004251.4  

    Unigene Cluster for RAB9A:

    RAB9A, member RAS oncogene family
    Hs.495704  [show with all ESTs]
    Unigene Representative Sequence: NM_004251
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000464506(uc004cvm.3 uc010neh.3) ENST00000243325

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    Selected qRT-PCR Assays for microRNAs that regulate RAB9A (see all 15):
    hsa-miR-3163 hsa-miR-136 hsa-miR-137 hsa-miR-15a hsa-miR-497 hsa-miR-519e* hsa-miR-515-5p hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidRAB9A 3' UTR sequence
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    Additional mRNA sequence: 

    AF498944.1 AK290505.1 BC017265.2 CR450362.1 U44103.1 

    5 DOTS entries:

    DT.113715  DT.95375785  DT.91822585  DT.100832671  DT.40273883 

    Selected AceView cDNA sequences (see all 149):

    AI089270 CB997928 BM717088 CD515129 AA451667 AI224161 BM353471 BM980331 
    CA308701 CF528667 AW949345 AI167166 NM_004251 CA388797 BF340019 BM705692 
    AI674590 CR612058 AI078735 AI274518 BC017265 BE326331 BF109729 CB216127 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB9A expression in normal human tissues (normalized intensities)      RAB9A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGATGGAGA
    RAB9A Expression
    About this image


    RAB9A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    RAB9A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB9A Protein Expression

    Genevestigator expression for RAB9A

    SOURCE GeneReport for Unigene cluster: Hs.495704
        Custom PCR Arrays for RAB9A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB9A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RAB9A gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab91 , 5 RAB9, member RAS oncogene family1, 5 90.38(n)1
    95.52(a)1
      X (77.47 cM)5
    563821  NM_019773.21  NP_062747.11 
     1664572535 
    chicken
    (Gallus gallus)
    Aves RAB9A1 RAB9A, member RAS oncogene family 83.75(n)
    94.03(a)
      418635  NM_001008678.1  NP_001008678.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB9A6
    RAB9A, member RAS oncogene family
    94(a)
    1 ↔ 1
    3(120462744-120465232)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.172192 Xenopus laevis transcribed sequence with moderate similarity more 76.91(n)    BX852225.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab9a1 RAB9A, member RAS oncogene family 72.8(n)
    85.07(a)
      751756  NM_001045466.1  NP_001038931.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab73 endosome to lysosome transport RAB
    small monomeric more
    55(a)
    (best of 2)
      95D5   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPT76
    Rab family GTPase; GTP-binding protein of the rab ...
    48(a)
    1 → many
    XIII(267174-267800) YML001W


    ENSEMBL Gene Tree for RAB9A (if available)
    TreeFam Gene Tree for RAB9A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB9A gene
    RABL2B2  RAB7A2  RAB9B2  RAB322  RAB7L12  RAB382  RABL2A2  
    Selected SIMAP similar genes for RAB9A using alignment to 1 protein entry:     RAB9A_HUMAN(see all similar genes):
    RAB9B    RANP1    RAB8B    DKFZp686J07132    RAB7A    RAB23
    RAB15    DKFZp547A0616    RAB1B    RAB41    RAP2B    RAB11B
    RAB11A    RAB21    RAB30    RAB4A    RAB7B    MRAS

    RAB9A for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for RAB9A (see all 7)
    PGOHUM00000237172 PGOHUM00000249393 PGOHUM00000233874 PGOHUM00000233878 PGOHUM00000233995


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB9A (see all 308)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs169791281,2
    C,F,H--13705262(+) GTAAAA/GGAATC 2 -- us2k17Minor allele frequency- G:0.02NA NS EA 518
    rs59799451,2
    C,A--13705592(+) CTAACA/TTTCTT 2 -- us2k15Minor allele frequency- T:0.00NA WA CSA 7
    rs1915043161,2
    --13705652(+) CTTTCA/TAAGCT 2 -- us2k10--------
    rs1435660181,2
    C--13705820(+) TTTATA/GAGATC 2 -- us2k10--------
    rs1471620861,2
    C--13706010(+) TGTTCA/GTATAT 2 -- us2k10--------
    rs128488931,2
    C--13706110(+) AAACGT/GTTATA 2 -- us2k11Minor allele frequency- G:0.00NA 2
    rs1841954051,2
    --13706196(+) GTGTCA/GTTTTC 2 -- us2k10--------
    rs1887447451,2
    --13706465(+) AGGGCA/TTGGTG 2 -- us2k10--------
    rs1916127211,2
    --13706561(+) CCTCAA/TGTGGG 2 -- us2k10--------
    rs1835994821,2
    C--13707256(+) TGTTCC/TCTCCG 2 -- ut510--------

    HapMap Linkage Disequilibrium report for RAB9A (13707240 - 13728625 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RAB9A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv528634CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300284    OMIM disorders: --

    10 diseases for RAB9A:    About MalaCards
    vaccinia    niemann-pick disease    pick's disease    measles
    tonsillitis    tuberculosis    hiv-1    endotheliitis
    thyroiditis    prostatitis


    RAB9A for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for RAB9A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB9A gene, integrated from 10 sources (see all 64):
    (articles sorted by number of sources associating them with RAB9A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene. (PubMed id 9126495)1, 2, 3, 9 Davies J.P.... Ioannou Y.A. (Genomics 1997)
    2. Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. (PubMed id 18243103)1, 2 Burguete A.S.... Pfeffer S.R. (Cell 2008)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target. (PubMed id 15263003)1, 2 Chen L....Meehan E.J. (J. Biol. Chem. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus. (PubMed id 16140752)1, 9 Murray J.L....Hodge T.W. (J. Virol. 2005)
    7. TIP47 is a key effector for Rab9 localization. (PubMed id 16769818)1, 9 Aivazian D.... Pfeffer S. (J. Cell Biol. 2006)
    8. Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment. (PubMed id 18681838)1, 9 Walter M....Ioannou Y.A. (Biol. Cell 2009)
    9. Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes. (PubMed id 12576506)1, 9 Walter M....Ioannou Y.A. (J. Lipid Res. 2003)
    10. The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. (PubMed id 16176980)2, 9 Johansson M.... Olkkonen V.M. (Mol. Biol. Cell 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9367 HGNC: 9792 AceView: RAB9A Ensembl:ENSG00000123595 euGenes: HUgn9367
    ECgene: RAB9A Kegg: 9367 H-InvDB: RAB9A

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB9A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB9A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB9A gene:
    Search GeneIP for patents involving RAB9A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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