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Aliases for RAB9A Gene

Aliases for RAB9A Gene

  • RAB9A, Member RAS Oncogene Family 2 3
  • RAB9 3 4 6
  • RAB9, Member RAS Oncogene Family 2 3
  • Ras-Related Protein Rab-9A 3

External Ids for RAB9A Gene

Previous HGNC Symbols for RAB9A Gene

  • RAB9

Previous GeneCards Identifiers for RAB9A Gene

  • GC0XP012946
  • GC0XP012527
  • GC0XP013068
  • GC0XP013466
  • GC0XP013617
  • GC0XP011465

Summaries for RAB9A Gene

GeneCards Summary for RAB9A Gene

RAB9A (RAB9A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB9A include vaccinia. Among its related pathways are Cytoskeletal Signaling and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RABL2A.

UniProtKB/Swiss-Prot for RAB9A Gene

  • Involved in the transport of proteins between the endosomes and the trans Golgi network

Gene Wiki entry for RAB9A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB9A Gene

Genomics for RAB9A Gene

Regulatory Elements for RAB9A Gene

Genomic Location for RAB9A Gene

13,689,121 bp from pter
13,710,506 bp from pter
21,386 bases
Plus strand

Genomic View for RAB9A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB9A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB9A Gene

Proteins for RAB9A Gene

  • Protein details for RAB9A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ras-related protein Rab-9A
    Protein Accession:
    Secondary Accessions:
    • A8K390
    • Q6ICN1

    Protein attributes for RAB9A Gene

    201 amino acids
    Molecular mass:
    22838 Da
    Quaternary structure:
    • Interacts (preferentially in its GTP-bound form) with GCC2 (via its GRIP domain).

    Three dimensional structures from OCA and Proteopedia for RAB9A Gene

neXtProt entry for RAB9A Gene

Proteomics data for RAB9A Gene at MOPED

Post-translational modifications for RAB9A Gene

  • Ubiquitination at Lys103
  • Modification sites at PhosphoSitePlus

Other Protein References for RAB9A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for RAB9A (RAB9A)

No data available for DME Specific Peptides for RAB9A Gene

Domains for RAB9A Gene

Gene Families for RAB9A Gene

Suggested Antigen Peptide Sequences for RAB9A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the small GTPase superfamily. Rab family.
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RAB9A: view

Function for RAB9A Gene

Molecular function for RAB9A Gene

UniProtKB/Swiss-Prot Function:
Involved in the transport of proteins between the endosomes and the trans Golgi network

Gene Ontology (GO) - Molecular Function for RAB9A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity IDA 15263003
GO:0005515 protein binding IPI 18243103
GO:0005525 GTP binding IDA 15263003
GO:0019003 GDP binding IDA 15263003
genes like me logo Genes that share ontologies with RAB9A: view

Phenotypes for RAB9A Gene

MGI mutant phenotypes for RAB9A:
inferred from 1 alleles
GenomeRNAi human phenotypes for RAB9A:
genes like me logo Genes that share phenotypes with RAB9A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAB9A Gene

Localization for RAB9A Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB9A Gene

Cell membrane; Lipid-anchor; Cytoplasmic side. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Note=Colocalizes with OSBPL1A at the late endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis.

Subcellular locations from

Jensen Localization Image for RAB9A Gene COMPARTMENTS Subcellular localization image for RAB9A gene
Compartment Confidence
endosome 5
lysosome 5
plasma membrane 5
vacuole 5
cytosol 3
endoplasmic reticulum 3
golgi apparatus 3
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for RAB9A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005737 cytoplasm --
GO:0005764 lysosome IDA 15078902
genes like me logo Genes that share ontologies with RAB9A: view

Pathways for RAB9A Gene

genes like me logo Genes that share pathways with RAB9A: view

Gene Ontology (GO) - Biological Process for RAB9A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006184 obsolete GTP catabolic process --
GO:0006886 intracellular protein transport IBA --
GO:0006913 nucleocytoplasmic transport --
GO:0007165 signal transduction --
GO:0007264 small GTPase mediated signal transduction --
genes like me logo Genes that share ontologies with RAB9A: view

Drugs for RAB9A Gene

(2) Drugbank Compounds for RAB9A Gene

Compound Status Synonyms Cas Number PubChem ID Type Actions PubMed IDs
Benzoic Acid
65-85-0 243 Target experimental
146-91-8 6453837 Target experimental

(4) Novoseek inferred chemical compound relationships for RAB9A Gene

Compound -log(P) Hits PubMed IDs
mannose 6-phosphate 59.7 2
gdp 46.5 2
cholesterol 34.9 3
lipid 6.54 4
genes like me logo Genes that share compounds with RAB9A: view

Transcripts for RAB9A Gene

Unigene Clusters for RAB9A Gene

RAB9A, member RAS oncogene family:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RAB9A Gene

No ASD Table

Relevant External Links for RAB9A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB9A Gene

mRNA expression in normal human tissues for RAB9A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for RAB9A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (10.4) and Bone (9.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAB9A Gene

SOURCE GeneReport for Unigene cluster for RAB9A Gene Hs.495704

genes like me logo Genes that share expressions with RAB9A: view

Expression partners for RAB9A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for RAB9A Gene

Orthologs for RAB9A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RAB9A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RAB9A 35
  • 91.04 (n)
  • 97.51 (a)
RAB9A 36
  • 97 (a)
(Canis familiaris)
Mammalia RAB9A 35
  • 93.7 (n)
  • 99.5 (a)
RAB9A 36
  • 100 (a)
(Mus musculus)
Mammalia Rab9 35
  • 90.38 (n)
  • 95.52 (a)
Rab9 16
Rab9 36
  • 96 (a)
(Pan troglodytes)
Mammalia RAB9A 35
  • 100 (n)
  • 100 (a)
RAB9A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Rab9a 35
  • 91.38 (n)
  • 95.52 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 80 (a)
-- 36
  • 97 (a)
(Ornithorhynchus anatinus)
Mammalia RAB9A 36
  • 98 (a)
(Gallus gallus)
Aves RAB9A 35
  • 83.75 (n)
  • 94.03 (a)
RAB9A 36
  • 94 (a)
(Anolis carolinensis)
Reptilia RAB9A 36
  • 94 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rab9a 35
  • 78.44 (n)
  • 90.05 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.17219 35
(Danio rerio)
Actinopterygii rab9a 35
  • 72.8 (n)
  • 85.07 (a)
rab9a 36
  • 85 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9994 37
  • 55 (a)
Rab7 37
  • 55 (a)
Rab9 36
  • 40 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YPT7 36
  • 48 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 55 (a)
Species with no ortholog for RAB9A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RAB9A Gene

Gene Tree for RAB9A (if available)
Gene Tree for RAB9A (if available)

Paralogs for RAB9A Gene

Paralogs for RAB9A Gene

genes like me logo Genes that share paralogs with RAB9A: view

Variants for RAB9A Gene

Sequence variations from dbSNP and Humsavar for RAB9A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs956784 -- 13,701,372(+) TCTAC(A/G)TTACA intron-variant
rs956785 -- 13,701,494(-) TTAGA(C/T)TGCAC intron-variant
rs2028065 -- 13,706,618(+) ggtct(C/G)gaact intron-variant
rs2370241 -- 13,691,388(+) tgggc(A/G)cggtg intron-variant
rs4830888 -- 13,692,814(+) TTTGG(C/T)TTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RAB9A Gene

Variant ID Type Subtype PubMed ID
nsv528634 CNV Gain 19592680

Relevant External Links for RAB9A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAB9A Gene

Disorders for RAB9A Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for RAB9A Gene in MalaCards »

(1) Disease for RAB9A Gene

genes like me logo Genes that share disorders with RAB9A: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RAB9A Gene

Publications for RAB9A Gene

  1. Cloning and mapping of human Rab7 and Rab9 cDNA sequences and identification of a Rab9 pseudogene. (PMID: 9126495) Davies J.P. … Ioannou Y.A. (Genomics 1997) 2 3 4 23
  2. Rab9 GTPase is required for replication of human immunodeficiency virus type 1, filoviruses, and measles virus. (PMID: 16140752) Murray J.L. … Hodge T.W. (J. Virol. 2005) 3 23
  3. The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments. (PMID: 16176980) Johansson M. … Olkkonen V.M. (Mol. Biol. Cell 2005) 4 23
  4. Endosomal lipid accumulation in NPC1 leads to inhibition of PKC, hypophosphorylation of vimentin and Rab9 entrapment. (PMID: 18681838) Walter M. … Ioannou Y.A. (Biol. Cell 2009) 3 23
  5. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (PMID: 21255211) Seto S. … Koide Y. (Traffic 2011) 3 4

Products for RAB9A Gene

  • Addgene plasmids for RAB9A

Sources for RAB9A Gene

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