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RAB7L1 Gene

protein-coding   GIFtS: 54
GCID: GC01M205738

RAB7, Member RAS Oncogene Family-Like 1


(Previous symbol: RAB7L)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB7, Member RAS Oncogene Family-Like 11 2
RAB7L1 2
Rab-7-Like Protein 12 3
Ras-Related Protein Rab-7L12

External Ids:    HGNC: 97891   Entrez Gene: 89342   Ensembl: ENSG000001172807   OMIM: 6039495   UniProtKB: O149663   

Export aliases for RAB7L1 gene to outside databases

Previous GC identifers: GC01M203658 GC01M201198 GC01M202098 GC01M202915 GC01M202469 GC01M204003 GC01M176901


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB7L1 Gene:
RAB7L1 (RAB7, member RAS oncogene family-like 1) is a protein-coding gene. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RABL2B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB7L1 gene promoter:
         CREB   ATF-2   deltaCREB   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB7L1 promoter sequence
   Search Chromatin IP Primers for RAB7L1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB7L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32

RAB7L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB7L1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M205738:  view genomic region     (about GC identifiers)

Start:
205,737,114 bp from pter      End:
205,744,610 bp from pter
Size:
7,497 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAB7L_HUMAN, O14966 (See protein sequence)
Recommended Name: Ras-related protein Rab-7L1  
Size: 203 amino acids; 23155 Da
Secondary accessions: B4E1K3 C9JE77
Alternative splicing: 3 isoforms:  O14966-1   O14966-2   O14966-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAB7L1: NX_O14966

Explore proteomics data for RAB7L1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB7L1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001129134.1  NP_001129135.1  NP_001129136.1  NP_003920.1  

    ENSEMBL proteins: 
     ENSP00000356107   ENSP00000235932   ENSP00000431483   ENSP00000416613   ENSP00000389899  
     ENSP00000402910  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry O14966

    ProtoNet protein and cluster: O14966

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB7L_HUMAN, O14966
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB7L1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for RAB7L1:
    RAB-related GTP binding protein 7,homolog 1,RAS oncogene superfamily member,ubiquitously expressed,involved in the
    regulation of exocytotic and endocytotic pathways (signal transduction)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS9284931
    GO:0005515protein binding ----
    GO:0005525GTP binding IEA--
         
    Find genes that share ontologies with RAB7L1           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for RAB7L1:
     Decreased influenza A virus in  Decreased viability of wild-ty  Increased HPV18 LCR reporter a  Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rab7l1):
     vision/eye 

    Find genes that share phenotypes with RAB7L1           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB7L1
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    hsa-mir-196a-5p (MIRT026087)

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    Selected qRT-PCR Assays for microRNAs that regulate RAB7L1 (see all 23):
    hsa-miR-26a-2* hsa-miR-607 hsa-miR-181a-2* hsa-miR-374c hsa-miR-3122 hsa-miR-124 hsa-miR-654-5p hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidRAB7L1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB7L1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB7L_HUMAN, O14966: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    nucleus3
    endosome1
    extracellular1
    golgi apparatus1
    mitochondrion1
    vacuole1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----

    Find genes that share ontologies with RAB7L1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB7L1
    Interactions:

        Search GeneGlobe Interaction Network for RAB7L1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for RAB7L1 (O149663 ENSP000002359324) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LSM7Q9UK453, ENSP000002526224I2D: score=4 STRING: ENSP00000252622
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS9284931
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    Find genes that share ontologies with RAB7L1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB7L1 (RAB7L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB7L1 gene (4 alternative transcripts): 
    NM_001135662.1  NM_001135663.1  NM_001135664.1  NM_003929.2  

    Unigene Cluster for RAB7L1:

    RAB7, member RAS oncogene family-like 1
    Hs.115325  [show with all ESTs]
    Unigene Representative Sequence: NM_001135663
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367139(uc001hdf.4 uc009xbp.3 uc001hde.4 uc010prr.2 uc009xbq.3)
    ENST00000235932 ENST00000528078 ENST00000437324 ENST00000446390 ENST00000468887
    ENST00000414729 ENST00000492534 ENST00000533111
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate RAB7L1 (see all 23):
    hsa-miR-26a-2* hsa-miR-607 hsa-miR-181a-2* hsa-miR-374c hsa-miR-3122 hsa-miR-124 hsa-miR-654-5p hsa-miR-7-1*
    SwitchGear 3'UTR luciferase reporter plasmidRAB7L1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB7L1
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    OriGene ORF clones in mouse, rat for RAB7L1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): RAB7L1 (NM_001135662)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB7L1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB7L1
      QuantiTect SYBR Green Assays in human, mouse, rat RAB7L1
      QuantiFast Probe-based Assays in human, mouse, rat RAB7L1

    Additional mRNA sequence: 

    AK223514.1 AK303879.1 AK308359.1 AK311085.1 AK313000.1 BC002585.2 BT019540.1 BX647960.1 
    CR542010.1 D84488.1 

    15 DOTS entries:

    DT.91917723  DT.100719882  DT.121339746  DT.121339738  DT.95278242  DT.92432170  DT.86794137  DT.100022904 
    DT.101984020  DT.121339756  DT.121339739  DT.87012880  DT.95144249  DT.99989543  DT.100751849 

    Selected AceView cDNA sequences (see all 147):

    CF528995 BE221777 AW028502 CA950844 AI801856 BE464327 AL531102 BF063786 
    BM561547 AW582760 BX642353 CR542010 BE315408 BE326920 BG757213 BG685291 
    BE501959 BM728047 CK903149 BM842035 AW271534 BX374162 BE272266 BU594328 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RAB7L1 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d · 4e ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e · 6f
    SP1:                                            -     -                                         -     -                                                   
    SP2:                                -     -     -     -                                         -     -                                                   
    SP3:                          -     -     -     -     -     -                                   -     -                                                   
    SP4:                                -     -     -     -     -                                   -     -                                                   
    SP5:                                            -     -     -                                   -     -                                                   


    ECgene alternative splicing isoforms for RAB7L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB7L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RAB7L1 Expression
    About this image

    RAB7L1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB7L1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.115325

    UniProtKB/Swiss-Prot: RAB7L_HUMAN, O14966
    Tissue specificity: Ubiquitous

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    QuantiFast Probe-based Assays in human, mouse, rat RAB7L1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB7L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for RAB7L1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab7l11 , 5 RAB7, member RAS oncogene family-like 11, 5 90.97(n)1
    93.6(a)1
      1 (57.21 cM)5
    2264221  NM_144875.21  NP_659124.21 
     1318672245 
    chicken
    (Gallus gallus)
    Aves RAB7L11 RAB7, member RAS oncogene family-like 1 75.53(n)
    79.31(a)
      419836  XM_417967.3  XP_417967.2 
    lizard
    (Anolis carolinensis)
    Reptilia RAB7L16
    RAB7, member RAS oncogene family-like 1
    75(a)
    1 ↔ 1
    GL343228.1(644215-666202)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.321952 Xenopus laevis transcribed sequence with moderate similarity more 71.65(n)    CA792690.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch73-173m3.36
    si:ch73-173m3.3
    46(a)
    many ↔ many
    21(29292600-29304551) ENSDARG00000074719


    ENSEMBL Gene Tree for RAB7L1 (if available)
    TreeFam Gene Tree for RAB7L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB7L1 gene
    RABL2B2  RAB9A2  RAB7A2  RAB9B2  RAB322  RAB382  RABL2A2  
    Selected SIMAP similar genes for RAB7L1 using alignment to 3 protein entries:     RAB7L_HUMAN (see all proteins) (see all similar genes):
    RAB38    RAB32    RAB8B    RAB43    RAB7A    RAB27B
    RAB3C    RAB28    RAB15    RAB3A    RAB27A    RAB11A
    RAB35    RAB13    RAB19    RAB23    RAB30    RAB5C

    Find genes that share paralogs with RAB7L1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB7L1 (see all 208)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1996594501,2
    --205736661(+) CATGT-/AATCCAT 4 -- int10--------
    rs17721521,2
    C,F,A,H--205736662(+) CATGTA/TCCATC 4 -- int18Minor allele frequency- T:0.16MN NS EA WA NA 716
    rs16189361,2
    C,F,A--205736663(-) TGATGT/GAACAT 4 -- int16Minor allele frequency- G:0.18MN NA WA EA 428
    rs66619161,2
    C,F,A--205736674(+) AGTACT/CGAATT 4 -- int13Minor allele frequency- C:0.06CSA WA 122
    rs759252641,2
    --205736763(+) AAGAAA/GGTATT 4 -- int10--------
    rs1919283681,2
    --205737040(+) ATTTCC/TGCAAT 4 -- int10--------
    rs1462386251,2
    C--205737082(+) TGACAA/TACTCA 4 -- int10--------
    rs120645761,2
    C,H--205737180(+) CAATTA/GTCTCT 4 -- ut315Minor allele frequency- G:0.00NS EA WA 534
    rs8440051,2
    C,F,A,H--205737450(+) CAGAAC/TATATA 4 -- ut31 ese317Minor allele frequency- T:0.21NS EA NA WA CSA 796
    rs1124068331,2
    C,F--205737511(+) TCTCTG/ATATCT 4 -- ut312Minor allele frequency- A:0.04NA 122

    HapMap Linkage Disequilibrium report for RAB7L1 (205737114 - 205744610 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RAB7L1: --
    Human Gene Mutation Database (HGMD): RAB7L1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB7L1
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB7L1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603949    OMIM disorders: --


    Find genes that share disorders with RAB7L1           About GenesLikeMe

    Genetic Association Database (GAD): RAB7L1
    Human Genome Epidemiology (HuGE) Navigator: RAB7L1 (1 document)

    Export disorders for RAB7L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB7L1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with RAB7L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and chromosome assignment to 1q32 of a human cDNA (RAB7L1) encoding a small GTP-binding protein, a member of the RAS superfamily. (PubMed id 9284931)1, 2, 3, 9 Shimizu F.... Takahashi E. (Cytogenet. Cell Genet. 1997)
    2. Genetic variability at the PARK16 locus. (PubMed id 20683486)1, 4 Tucci A....PaisA!n-Ruiz C. (Eur. J. Hum. Genet. 2010)
    3. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. (PubMed id 19915576)1, 4 Satake W....Toda T. (Nat. Genet. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population. (PubMed id 23269536)1 Sun J....Mo Z. (Hum. Genet. 2013)
    6. RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk. (PubMed id 23395371)1 MacLeod D.A....Abeliovich A. (Neuron 2013)
    7. Alzheimer's disease and Parkinson's disease genome-wide association study top hits and risk of Parkinson's disease in Korean population. (PubMed id 23820587)1 Chung S.J....Song K. (Neurobiol. Aging 2013)
    8. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. (PubMed id 23449627)1 Cousminer D.L....WidAcn E. (Hum. Mol. Genet. 2013)
    9. Association of sequence alterations in the putative promoter of RAB7L1 with a reduced parkinson disease risk. (PubMed id 22232350)1 Gan-Or Z....Orr-Urtreger A. (Arch. Neurol. 2012)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8934 HGNC: 9789 AceView: RAB7L1 Ensembl:ENSG00000117280 euGenes: HUgn8934
    ECgene: RAB7L1 H-InvDB: RAB7L1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB7L1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB7L1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB7L1 gene:
    Search GeneIP for patents involving RAB7L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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