Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RAB7B Gene

protein-coding   GIFtS: 39
GCID: GC01U901021

RAB7B, Member RAS Oncogene Family

  See RAB7B-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
RAB7B, Member RAS Oncogene Family1 2
RAB72
Ras-Related Protein Rab-72
Ras-Related Protein Rab-7b2

External Ids:    HGNC: 305131   Entrez Gene: 3383822   UniProtKB: Q96AH83   

Export aliases for RAB7B gene to outside databases

Previous GC identifer: GC00P1O0000


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for RAB7B Gene:
RAB7B (RAB7B, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB7B include acute promyelocytic leukemia. GO annotations related to this gene include GTP binding.

UniProtKB/Swiss-Prot: RAB7B_HUMAN, Q96AH8
Function: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative
regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by
promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting
lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6
production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the
EGF- and EGFR degradation pathway

Gene Wiki entry for RAB7B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  
Regulatory elements:
   Search for regulatory transcription factor binding sites for RAB7B
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for RAB7B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB7B


Genomic Location:
Chromosome:1   

Entrez Gene cytogenetic band: 1q32   HGNC cytogenetic band: 1q32

GeneLoc information about chromosome 1        


(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RAB7B_HUMAN, Q96AH8 (See protein sequence)
Recommended Name: Ras-related protein Rab-7b  
Size: 199 amino acids; 22511 Da

Explore the universe of human proteins at neXtProt for RAB7B: NX_Q96AH8

Explore proteomics data for RAB7B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB7B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001157994.1  NP_796377.3  

    RAB7B Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for RAB7B
    OriGene Protein Over-expression Lysate for RAB7B
    OriGene MassSpec for RAB7B
    OriGene Custom Protein Services for RAB7B
    GenScript Custom Purified and Recombinant Proteins Services for RAB7B
    Novus Biologicals RAB7B Proteins
    Novus Biologicals RAB7B Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RAB7B

     
    Search eBioscience for Proteins for RAB7B 

     
    antibodies-online proteins for RAB7B (8 products) 

     
    Search antibodies-online for peptides for RAB7B

    RAB7B Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RAB7B
    Novus Biologicals RAB7B Antibodies
    Abcam antibodies for RAB7B
    Cloud-Clone Corp. Antibodies for RAB7B
    Search ThermoFisher Antibodies for RAB7B
    LSBio Antibodies in human, mouse, rat for RAB7B
    antibodies-online antibodies for RAB7B (24 products) 

    RAB7B Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RAB7B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RAB7B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RAB7B
    Cloud-Clone Corp. CLIAs for RAB7B
    Search eBioscience for ELISAs for RAB7B 
    antibodies-online kits for RAB7B (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q96AH8

    ProtoNet protein and cluster: Q96AH8

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB7B_HUMAN, Q96AH8
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB7B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB7B_HUMAN, Q96AH8
    Function: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative
    regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by
    promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting
    lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6
    production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the
    EGF- and EGFR degradation pathway

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005525GTP binding IEA--
         
    Find genes that share ontologies with RAB7B           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB7B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB7B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAB7B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB7B

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat RAB7B using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate RAB7B
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RAB7B
    Predesigned siRNA for gene silencing in human, mouse, rat RAB7B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RAB7B

    Clone
    Products:
         
    OriGene clones in human, mouse for RAB7B (see all 12)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RAB7B (NM_177403)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB7B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB7B

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RAB7B
    Browse ESI BIO Cell Lines and PureStem Progenitors for RAB7B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB7B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    RAB7B_HUMAN, Q96AH8: Late endosome. Lysosome. Golgi apparatus, trans-Golgi network. Golgi apparatus. Cytoplasmic
    vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity).
    Note=Recruited to phagosomes containing S.aureus or M.tuberculosis

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005764lysosome IDA--
    GO:0005770late endosome IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0005802trans-Golgi network IDA--
    GO:0030670phagocytic vesicle membrane IEA--

    Find genes that share ontologies with RAB7B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for RAB7B About    
    See pathways by source

    SuperPathContained pathways About
    1Salmonella infection (KEGG)
    Salmonella infection0.30
    2Phagosome
    Phagosome
    3Amoebiasis
    Amoebiasis


    Find genes that share SuperPaths with RAB7B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for RAB7B
        Remodeling of Adherens Junctions
    Epithelial Tight Junctions


    3 Kegg Pathways  (Kegg details for RAB7B):
        Phagosome
    Salmonella infection
    Amoebiasis

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB7B
    Interactions:

        Search GeneGlobe Interaction Network for RAB7B

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport IEA--
    GO:0032755positive regulation of interleukin-6 production IMP--
    GO:0034144negative regulation of toll-like receptor 4 signaling pathway ISS--
    GO:0034164negative regulation of toll-like receptor 9 signaling pathway ISS--

    Find genes that share ontologies with RAB7B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB7B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RAB7B gene (2 alternative transcripts): 
    NM_001164522.1  NM_177403.4  

    Unigene Cluster for RAB7B:

    RAB7B, member RAS oncogene family
    Hs.534612  [show with all ESTs]
    Unigene Representative Sequence: NM_177403
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RAB7B using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate RAB7B
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RAB7B
    Predesigned siRNA for gene silencing in human, mouse, rat RAB7B
    Clone
    Products:
         
    OriGene clones in human, mouse for RAB7B (see all 12)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RAB7B (NM_177403)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB7B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB7B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RAB7B
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB7B
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RAB7B
      QuantiTect SYBR Green Assays in human, mouse, rat RAB7B
      QuantiFast Probe-based Assays in human, mouse, rat RAB7B

    Additional mRNA sequence: 

    AK122657.1 AK127140.1 AY094596.1 BC007382.1 BC017092.1 

    7 DOTS entries:

    DT.95157154  DT.410687  DT.101981046  DT.444511  DT.70104449  DT.100711980  DT.40124041 

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RAB7B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGCAGCTTG
    RAB7B Expression
    About this image


    RAB7B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 2 entries
             Umbilical cord blood-derived hematopoietic stem cells
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Umbilical cord blood-derived hematopoietic stem cells
    RAB7B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB7B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.534612

    UniProtKB/Swiss-Prot: RAB7B_HUMAN, Q96AH8
    Tissue specificity: Expressed in heart, placenta, lung, skeletal muscle and peripheral blood leukocyte

        Custom PCR Arrays for RAB7B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for RAB7B
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB7B
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RAB7B
    QuantiTect SYBR Green Assays in human, mouse, rat RAB7B
    QuantiFast Probe-based Assays in human, mouse, rat RAB7B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB7B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for RAB7B gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 5430435G22Rik1 RIKEN cDNA 5430435G22 gene 85.43(n)
    88.44(a)
      226421  NM_145509.2  NP_663484.1 
    chicken
    (Gallus gallus)
    Aves LOC7717821 ras-related protein Rab-7b-like 73.53(n)
    71.86(a)
      771782  XM_004934948.1  XP_004935005.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rab7b1 RAB7B, member RAS oncogene family 62.98(n)
    61.31(a)
      100124979  NM_001102911.1  NP_001096381.1 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RAB7B gene
    Selected SIMAP similar genes for RAB7B using alignment to 1 protein entry:     RAB7B_HUMAN(see all similar genes):
    RAB23    RAB7A    RAB5B    RAB3A    RAB5C    RAB32
    RAB25    RAB4A    RANP1    RAB11B    RAB39B    RAB9A
    RAB4B    MRAS    RAB3B    RAB3C    RAB30    RAB2A

    Find genes that share paralogs with RAB7B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing RAB7B
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB7B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for RAB7B:    
    About MalaCards
    acute promyelocytic leukemia


    Find genes that share disorders with RAB7B           About GenesLikeMe


    Export disorders for RAB7B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RAB7B gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with RAB7B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Rab7b, a novel lysosome-associated small GTPase, is involved in monocytic differentiation of human acute promyelocytic leukemia cells. (PubMed id 15144907)1, 2, 3, 9 Yang M.... Cao X. (Biochem. Biophys. Res. Commun. 2004)
    2. Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 association. (PubMed id 20953574)1, 2 He D.... Cai Z. (J. Mol. Med. 2011)
    3. Rab7b controls trafficking from endosomes to the TGN. (PubMed id 20375062)1, 2 Progida C.... Bucci C. (J. Cell Sci. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection. (PubMed id 23345514)1 Day P.M....Schiller J.T. (J. Virol. 2013)
    6. Dynamics of Rab7b-dependent transport of sorting receptors. (PubMed id 22708738)1 Progida C....Bakke O. (Traffic 2012)
    7. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (PubMed id 21255211)2 Seto S.... Koide Y. (Traffic 2011)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. Rab7b and receptors trafficking. (PubMed id 21057625)2 Bucci C.... Progida C. (Commun. Integr. Biol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 338382 HGNC: 30513 euGenes: HUgn338382 ECgene: RAB7B
    Kegg: 338382 H-InvDB: RAB7B

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RAB7B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB7B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RAB7B gene:
    Search GeneIP for patents involving RAB7B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RAB7B  
     OriGene qPCR primer pairs and template standards for RAB7B   OriGene Protein Over-expression Lysate for RAB7B  
     OriGene MassSpec for RAB7B   OriGene clones in human, mouse for RAB7B  
     OriGene qSTAR qPCR primer pairs in human, mouse for RAB7B   OriGene Purified Protein for RAB7B  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RAB7B   OriGene Custom Protein Services for RAB7B  

     
     
     Block miRNA regulation of human, mouse, rat RAB7B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RAB7B
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB7B Predesigned siRNA for gene silencing in human, mouse, rat RAB7B
     QuantiFast Probe-based Assays in human, mouse, rat RAB7B QuantiTect SYBR Green Assays in human, mouse, rat RAB7B
     Custom PCR Arrays for RAB7B Search Chromatin IP Primers for RAB7B
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat RAB7B  Search GeneGlobe Interaction Network for RAB7B
     Search Regulatory tfbs for RAB7B
     GenScript Custom Purified and Recombinant Proteins Services for RAB7B GenScript cDNA clones with any tag delivered in your preferred vector for RAB7B
     GenScript Custom Assay Services for RAB7B GenScript Custom overexpressing Cell Line Services for RAB7B
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RAB7B
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RAB7B antibodies
     RAB7B proteins
     RAB7B lysates
     Antibodies for RAB7B
     See all of Abcam's Antibodies, Kits and Proteins for RAB7B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RAB7B
     Antibodies for RAB7B
     ELISAs for RAB7B
     CLIAs for RAB7B



     Browse ESI BIO Cell Lines and PureStem Progenitors for RAB7B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB7B
     Browse SwitchGear 3'UTR luciferase reporter plasmids for RAB7B
     Browse SwitchGear Promoter luciferase reporter plasmids for RAB7B
     Search ThermoFisher Antibodies for RAB7B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB7B
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB7B
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB7B
     LSBio Antibodies in human, mouse, rat for RAB7B
     Browse compounds at ApexBio
     Search Addgene for plasmids for RAB7B
      Search eBioscience for proteins for RAB7B
      Search eBioscience for elisas for RAB7B
      eBioscience FlowRNA Probe Sets
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     antibodies-online antibodies for RAB7B (24 products)
     antibodies-online kits for RAB7B (6 products)
      Search antibodies-online for peptides for RAB7B
     antibodies-online proteins for RAB7B (8 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RAB7B gene at Home site.
    Version: 3.12.234 23 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4