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RAB6B Gene

protein-coding   GIFtS: 53
GCID: GC03M133543

RAB6B, Member RAS Oncogene Family

Pneumococci & Pneumococcal Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB6B, Member RAS Oncogene Family1 2
Ras-Related Protein Rab-6B2
Small GTP-Binding Protein2
Small GTPase RAB6B2

External Ids:    HGNC: 149021   Entrez Gene: 515602   Ensembl: ENSG000001549177   UniProtKB: Q9NRW13   

Export aliases for RAB6B gene to outside databases

Previous GC identifers: GC03M130506 GC03M134292 GC03M134828 GC03M134868 GC03M135025 GC03M130921


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB6B Gene:
RAB6B (RAB6B, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB6B include smallpox, and tonsillitis. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB6C.

UniProtKB/Swiss-Prot: RAB6B_HUMAN, Q9NRW1
Function: Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in
retrograde transport in neuronal cells

Gene Wiki entry for RAB6B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RAB6B gene promoter:
         GR   AhR   p53   AML1a   GR-beta   Olf-1   Arnt   AREB6   FAC1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): RAB6B promoter sequence
   Search Chromatin IP Primers for RAB6B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB6B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.1   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q22.1

RAB6B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB6B gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M133543:  view genomic region     (about GC identifiers)

Start:
133,543,079 bp from pter      End:
133,614,691 bp from pter
Size:
71,613 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RAB6B_HUMAN, Q9NRW1 (See protein sequence)
Recommended Name: Ras-related protein Rab-6B  
Size: 208 amino acids; 23462 Da
Subunit: Interacts with CCDC64/BICDR1; leads to its accumulation in the pericentrosomal region (By similarity).
Interacts with RAB6KIFL. Interacts (GTP-bound) with BICD1 (via C-terminus); the interaction is direct. Interacts
(GDP-bound) with DYNLRB1. Interacts (GTP-bound) with APBA1/MINT1 isoform 2, also called Mint1_826, but not with
isoform 1
3 PDB 3D structures from and Proteopedia for RAB6B:
2E9S (3D)        2FE4 (3D)        2FFQ (3D)    
Secondary accessions: B2R5Z9 D3DND3 Q92929

Explore the universe of human proteins at neXtProt for RAB6B: NX_Q9NRW1

Explore proteomics data for RAB6B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB6B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057661.3  
    ENSEMBL proteins: 
     ENSP00000285208   ENSP00000418540   ENSP00000419381   ENSP00000419941   ENSP00000419526  
     ENSP00000417433   ENSP00000437797  

    RAB6B Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for RAB6B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9NRW1

    ProtoNet protein and cluster: Q9NRW1

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB6B_HUMAN, Q9NRW1
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RAB6B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB6B_HUMAN, Q9NRW1
    Function: Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in
    retrograde transport in neuronal cells

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity NAS10893188
    GO:0005515protein binding IPI--
    GO:0005525GTP binding IEA--
         
    RAB6B for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RAB6B:
     Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Synthetic lethal with c-Myc af 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rab6b):
     adipose tissue  behavior/neurological  growth/size/body  immune system 

    RAB6B for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB6B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB6B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAB6B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB6B

    miRNA
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    miRTarBase miRNAs that target RAB6B:
    hsa-mir-122-5p (MIRT003086)

    Block miRNA regulation of human, mouse, rat RAB6B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB6B (see all 93):
    hsa-miR-548j hsa-miR-607 hsa-miR-300 hsa-miR-3622b-3p hsa-miR-3613-3p hsa-miR-548a-5p hsa-miR-559 hsa-miR-627
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RAB6B
    Predesigned siRNA for gene silencing in human, mouse, rat RAB6B

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for RAB6B

    Clone
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    OriGene clones in human, mouse for RAB6B (see all 7)
    OriGene ORF clones in mouse, rat for RAB6B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAB6B (NM_016577)
    Sino Biological Human cDNA Clone for RAB6B
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB6B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB6B

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB6B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB6B_HUMAN, Q9NRW1: Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle. Note=Colocalizes with BICD1 at
    vesicular structures that align along microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    cytosol3
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005794Golgi apparatus NAS10893188

    RAB6B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB6B About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB6B
        Epithelial Tight Junctions



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB6B
    Interactions:

        GeneGlobe Interaction Network for RAB6B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB6B (Q9NRW13 ENSP000002852084) via UniProtKB, MINT, STRING, and/or I2D (see all 409)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process NAS10893188
    GO:0006886intracellular protein transport ----
    GO:0006890retrograde vesicle-mediated transport, Golgi to ER NAS10893188
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----

    RAB6B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB6B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAB6B gene: 
    NM_016577.3  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000285208(uc003epy.3 uc011blu.1) ENST00000469959 ENST00000486858
    ENST00000477759 ENST00000460865 ENST00000488969 ENST00000543906

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RAB6B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB6B (see all 93):
    hsa-miR-548j hsa-miR-607 hsa-miR-300 hsa-miR-3622b-3p hsa-miR-3613-3p hsa-miR-548a-5p hsa-miR-559 hsa-miR-627
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB6B
    Clone
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    OriGene ORF clones in mouse, rat for RAB6B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAB6B (NM_016577)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB6B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB6B
    Primer
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    OriGene qPCR primer pairs and template standards for RAB6B
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB6B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB6B
      QuantiTect SYBR Green Assays in human, mouse, rat RAB6B
      QuantiFast Probe-based Assays in human, mouse, rat RAB6B

    Selected AceView cDNA sequences (see all 188):

    BM977045 BM930021 AI825400 T33623 AI720211 AI435467 AI354686 AI140719 
    Z41808 BM672091 T33785 T09274 AL713646 AI034349 BQ721546 AK055102 
    BQ276245 BM697592 AI805050 AI375892 AL138062 BQ108682 AA890570 AW779669 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB6B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGTCAAAC
    RAB6B Expression
    About this image


    RAB6B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Kidney (Urinary System)
             S-shaped Body
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Eye (Sensory Organs)
             Retina
    RAB6B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB6B Protein Expression

    UniProtKB/Swiss-Prot: RAB6B_HUMAN, Q9NRW1
    Tissue specificity: Predominantly expressed in brain

        Custom PCR Arrays for RAB6B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB6B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RAB6B gene from Selected species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab6b1 , 5 RAB6B, member RAS oncogene family1, 5 92.31(n)1
    100(a)1
      9 (54.88 cM)5
    2701921  NM_173781.41  NP_776142.11 
     1031120745 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    80(a)
    many ↔ many
    4(1226255-1241469)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    87(a)
    many ↔ many
    GL343202.1(2280526-2298440)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rab6b1 RAB6B, member RAS oncogene family 79.01(n)
    93.75(a)
      100038231  NM_001097366.1  NP_001090835.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab6b1 RAB6B, member RAS oncogene family 79.33(n)
    95.19(a)
      558900  NM_001034179.1  NP_001029351.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab63 RAB small monomeric GTPase 84(a)   33C4   --
    worm
    (Caenorhabditis elegans)
    Secernentea C56E6.23 GTP-binding 37(a)   II(6524883-6525953)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPT6(YLR262C)4
    YPT61
    Rab family GTPase, Ras-like GTP binding protein involved more4
    YPT61
    58.54(n)1
    65.48(a)1
      12(668891-668244)4
    8509661, 4  NP_013363.11, 4 
    barley
    (Hordeum vulgare)
    Liliopsida CA029492.12   -- 72.91(n)    CA029492.1 


    ENSEMBL Gene Tree for RAB6B (if available)
    TreeFam Gene Tree for RAB6B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB6B gene
    RAB6C2  RAB6A2  RAB412  RAB362  RAB342  
    Selected SIMAP similar genes for RAB6B using alignment to 8 protein entries:     RAB6B_HUMAN (see all proteins) (see all similar genes):
    RAB6A'    RAB6A    RAB6C    RAB41    RAB5B    RAB5C
    RAB17    RAB8B    DKFZp313C1541    RAB2B    RAB30    RAB3A
    RAB37    RAB11B    RAB43    RAB11A    RAB8A    RAB5A

    RAB6B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB6B (see all 1539)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs168409941,2
    C,F,H--133542702(+) GAAGCA/CTGAGA 1 -- ds500124Minor allele frequency- C:0.21NA NS EA WA 2902
    rs1465344961,2
    --133542733(+) TCCCCC/GCTTCC 1 -- ds50010--------
    rs1409303351,2
    --133542784(+) TATATC/TGTACC 1 -- ds50010--------
    rs1502311611,2
    --133542798(+) GACTCA/GGTTCT 1 -- ds50010--------
    rs1164924121,2
    F--133542879(+) CATGAG/ATGTGT 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs732172371,2
    C,F--133542901(+) CCCTTC/TGGAGT 1 -- ds50011Minor allele frequency- T:0.08NA 120
    rs168410041,2
    C,F,H--133542969(+) GGTAGT/CGGACA 1 -- ds500111Minor allele frequency- C:0.23NA NS EA 806
    rs563199921,2
    C,F--133542994(+) GACAAA/GAGGGA 1 -- ds50015Minor allele frequency- G:0.08WA NA CSA 244
    rs1831640631,2
    --133543173(+) CGGCTA/GTGTCT 1 -- ut310--------
    rs609124921,2
    C--133543242(+) AAAGGG/AATGGG 1 -- ut312Minor allele frequency- A:0.07WA 120

    HapMap Linkage Disequilibrium report for RAB6B (133543079 - 133614691 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RAB6B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv829729CNV Loss17160897
    nsv877506CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB6B
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB6B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    8 diseases for RAB6B:    
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    smallpox    tonsillitis    melanoma    cervicitis
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    RAB6B for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
    Genetic Association Database (GAD): RAB6B
    Human Genome Epidemiology (HuGE) Navigator: RAB6B (2 documents)

    Export disorders for RAB6B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB6B gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with RAB6B)
        Utopia: connect your pdf to the dynamic
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    1. The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus. (PubMed id 10893188)1, 2, 9 Opdam F.J.M.... Fransen J.A.M. (J. Cell Sci. 2000)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Rab6 family proteins interact with the dynein light chain protein DYNLRB1. (PubMed id 18044744)1, 2 Wanschers B.F.J.... Fransen J. (Cell Motil. Cytoskeleton 2008)
    4. A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells. (PubMed id 17707369)1, 2 Wanschers B.F.J.F.... Fransen J.A. (Exp. Cell Res. 2007)
    5. The structure of human neuronal Rab6B in the active and inactive form. (PubMed id 16790928)1, 2 Garcia-Saez I.... Kozielski F. (Acta Crystallogr. D 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. RAB GTPases expressed in human melanoma cells. (PubMed id 9030196)1, 2 Chen D.... Gahl W.A. (Biochim. Biophys. Acta 1997)
    9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    10. A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6. (PubMed id 23737971)2 Thyrock A.... Barnekow A. (PLoS ONE 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51560 HGNC: 14902 AceView: RAB6B Ensembl:ENSG00000154917 euGenes: HUgn51560
    ECgene: RAB6B H-InvDB: RAB6B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB6B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB6B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB6B gene:
    Search GeneIP for patents involving RAB6B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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