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Aliases for RAB4B-EGLN2 Gene

Subcategory (RNA class) for RAB4B-EGLN2 Gene


Quality Score for this RNA gene is


Aliases for RAB4B-EGLN2 Gene

  • RAB4B-EGLN2 Readthrough (NMD Candidate) 2 3
  • RAB4B-EGLN2 Readthrough Long Non-Coding RNA 2 3
  • RAB4B-EGLN2 Readthrough (Non-Protein Coding) 3
  • RERT-LncRNA 3

External Ids for RAB4B-EGLN2 Gene

Previous GeneCards Identifiers for RAB4B-EGLN2 Gene

  • GC19U901528
  • GC19P041307
  • GC19P041286
  • GC19P041288

Summaries for RAB4B-EGLN2 Gene

Entrez Gene Summary for RAB4B-EGLN2 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RAB4B (RAB4B, member RAS oncogene family) and EGLN2 (egl nine homolog 2) genes on chromosome 19. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for RAB4B-EGLN2 Gene

RAB4B-EGLN2 (RAB4B-EGLN2 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. An important paralog of this gene is RAB42.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB4B-EGLN2 Gene

Genomics for RAB4B-EGLN2 Gene

Genomic Location for RAB4B-EGLN2 Gene

40,778,219 bp from pter
40,808,441 bp from pter
30,223 bases
Plus strand

Genomic View for RAB4B-EGLN2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB4B-EGLN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB4B-EGLN2 Gene

No data available for Regulatory Elements for RAB4B-EGLN2 Gene

Proteins for RAB4B-EGLN2 Gene

  • Protein details for RAB4B-EGLN2 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    HCG1995540, isoform CRA_c
    Protein Accession:
    Secondary Accessions:

    Protein attributes for RAB4B-EGLN2 Gene

    213 amino acids
    Molecular mass:
    23587 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RAB4B-EGLN2 Gene

Proteomics data for RAB4B-EGLN2 Gene at MOPED

Post-translational modifications for RAB4B-EGLN2 Gene

No Post-translational modifications

Other Protein References for RAB4B-EGLN2 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for RAB4B-EGLN2 Gene

Domains for RAB4B-EGLN2 Gene

Protein Domains for RAB4B-EGLN2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RAB4B-EGLN2: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RAB4B-EGLN2 Gene

Function for RAB4B-EGLN2 Gene

Gene Ontology (GO) - Molecular Function for RAB4B-EGLN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function --
GO:0003924 GTPase activity --
GO:0005525 GTP binding --
genes like me logo Genes that share ontologies with RAB4B-EGLN2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAB4B-EGLN2 Gene

Localization for RAB4B-EGLN2 Gene

Gene Ontology (GO) - Cellular Components for RAB4B-EGLN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005737 cytoplasm --
GO:0005886 plasma membrane --
GO:0016020 membrane --
genes like me logo Genes that share ontologies with RAB4B-EGLN2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for RAB4B-EGLN2 Gene

Pathways for RAB4B-EGLN2 Gene

SuperPathways for RAB4B-EGLN2 Gene

No Data Available

Interacting Proteins for RAB4B-EGLN2 Gene

Gene Ontology (GO) - Biological Process for RAB4B-EGLN2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006184 obsolete GTP catabolic process --
GO:0006886 intracellular protein transport --
GO:0006913 nucleocytoplasmic transport --
GO:0007165 signal transduction --
GO:0007264 small GTPase mediated signal transduction --
genes like me logo Genes that share ontologies with RAB4B-EGLN2: view

No data available for Pathways by source for RAB4B-EGLN2 Gene

Transcripts for RAB4B-EGLN2 Gene

mRNA/cDNA for RAB4B-EGLN2 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RAB4B-EGLN2 Gene

No ASD Table

Relevant External Links for RAB4B-EGLN2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB4B-EGLN2 Gene

mRNA expression in normal human tissues for RAB4B-EGLN2 Gene

genes like me logo Genes that share expressions with RAB4B-EGLN2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for RAB4B-EGLN2 Gene

Orthologs for RAB4B-EGLN2 Gene

This gene was present in the common ancestor of animals.

Orthologs for RAB4B-EGLN2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 77 (a)
(Canis familiaris)
Mammalia RAB4B 36
  • 89 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 91 (a)
(Mus musculus)
Mammalia Rab4b 36
  • 100 (a)
(Pan troglodytes)
Mammalia RAB4B 36
  • 100 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 92 (a)
(Danio rerio)
Actinopterygii rab4b 36
  • 92 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rab4 36
  • 77 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 69 (a)
Species with no ortholog for RAB4B-EGLN2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RAB4B-EGLN2 Gene

Gene Tree for RAB4B-EGLN2 (if available)
Gene Tree for RAB4B-EGLN2 (if available)

Paralogs for RAB4B-EGLN2 Gene

Paralogs for RAB4B-EGLN2 Gene

genes like me logo Genes that share paralogs with RAB4B-EGLN2: view

Variants for RAB4B-EGLN2 Gene

Structural Variations from Database of Genomic Variants (DGV) for RAB4B-EGLN2 Gene

Variant ID Type Subtype PubMed ID
nsv833832 CNV Loss 17160897
esv26234 CNV Loss 19812545
dgv1084e1 CNV Complex 17122850
nsv521459 CNV Loss 19592680

Relevant External Links for RAB4B-EGLN2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for RAB4B-EGLN2 Gene

Disorders for RAB4B-EGLN2 Gene

No disorders were found for RAB4B-EGLN2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RAB4B-EGLN2 Gene

Publications for RAB4B-EGLN2 Gene

  1. An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. (PMID: 23026137) Zhu Z. … Gao Y. (Cancer Res. 2012) 2 3
  2. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. (PMID: 22080838) Cho M.H. … . (Hum. Mol. Genet. 2012) 3
  3. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. (PMID: 20418890) (Nat. Genet. 2010) 3
  4. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3

Products for RAB4B-EGLN2 Gene

Sources for RAB4B-EGLN2 Gene

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