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Aliases for RAB4B-EGLN2 Gene

Subcategory (RNA class) for RAB4B-EGLN2 Gene


Quality Score for this RNA gene is


Aliases for RAB4B-EGLN2 Gene

  • RAB4B-EGLN2 Readthrough (NMD Candidate) 2 3
  • RAB4B-EGLN2 Readthrough Long Non-Coding RNA 2 3
  • RAB4B-EGLN2 Readthrough (Non-Protein Coding) 3
  • RERT-LncRNA 3

External Ids for RAB4B-EGLN2 Gene

Previous GeneCards Identifiers for RAB4B-EGLN2 Gene

  • GC19U901528
  • GC19P041307
  • GC19P041286
  • GC19P041288

Summaries for RAB4B-EGLN2 Gene

Entrez Gene Summary for RAB4B-EGLN2 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring RAB4B (RAB4B, member RAS oncogene family) and EGLN2 (egl nine homolog 2) genes on chromosome 19. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011]

GeneCards Summary for RAB4B-EGLN2 Gene

RAB4B-EGLN2 (RAB4B-EGLN2 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB42.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB4B-EGLN2 Gene

Genomics for RAB4B-EGLN2 Gene

Genomic Location for RAB4B-EGLN2 Gene

40,778,219 bp from pter
40,808,441 bp from pter
30,223 bases
Plus strand

Genomic View for RAB4B-EGLN2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB4B-EGLN2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB4B-EGLN2 Gene

No data available for Regulatory Elements for RAB4B-EGLN2 Gene

Proteins for RAB4B-EGLN2 Gene

  • Protein details for RAB4B-EGLN2 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    HCG1995540, isoform CRA_c
    Protein Accession:

    Protein attributes for RAB4B-EGLN2 Gene

    213 amino acids
    Molecular mass:
    23587 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RAB4B-EGLN2 Gene

Proteomics data for RAB4B-EGLN2 Gene at MOPED

Post-translational modifications for RAB4B-EGLN2 Gene

No Post-translational modifications

Other Protein References for RAB4B-EGLN2 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for RAB4B-EGLN2 Gene

Domains & Families for RAB4B-EGLN2 Gene

Protein Domains for RAB4B-EGLN2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RAB4B-EGLN2: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RAB4B-EGLN2 Gene

Function for RAB4B-EGLN2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAB4B-EGLN2 Gene

Localization for RAB4B-EGLN2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RAB4B-EGLN2 Gene

Pathways & Interactions for RAB4B-EGLN2 Gene

SuperPathways for RAB4B-EGLN2 Gene

No Data Available

Interacting Proteins for RAB4B-EGLN2 Gene

Gene Ontology (GO) - Biological Process for RAB4B-EGLN2 Gene


No data available for Pathways by source and SIGNOR curated interactions for RAB4B-EGLN2 Gene

Drugs & Compounds for RAB4B-EGLN2 Gene

No Compound Related Data Available

Transcripts for RAB4B-EGLN2 Gene

mRNA/cDNA for RAB4B-EGLN2 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RAB4B-EGLN2 Gene

No ASD Table

Relevant External Links for RAB4B-EGLN2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB4B-EGLN2 Gene

mRNA expression in normal human tissues for RAB4B-EGLN2 Gene

genes like me logo Genes that share expression patterns with RAB4B-EGLN2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RAB4B-EGLN2 Gene

Orthologs for RAB4B-EGLN2 Gene

This gene was present in the common ancestor of animals.

Orthologs for RAB4B-EGLN2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 77 (a)
(Canis familiaris)
Mammalia RAB4B 36
  • 89 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 91 (a)
(Mus musculus)
Mammalia Rab4b 36
  • 100 (a)
(Pan troglodytes)
Mammalia RAB4B 36
  • 100 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 92 (a)
(Danio rerio)
Actinopterygii rab4b 36
  • 92 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rab4 36
  • 77 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 69 (a)
Species with no ortholog for RAB4B-EGLN2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RAB4B-EGLN2 Gene

Gene Tree for RAB4B-EGLN2 (if available)
Gene Tree for RAB4B-EGLN2 (if available)

Paralogs for RAB4B-EGLN2 Gene

Paralogs for RAB4B-EGLN2 Gene

genes like me logo Genes that share paralogs with RAB4B-EGLN2: view

Variants for RAB4B-EGLN2 Gene

Structural Variations from Database of Genomic Variants (DGV) for RAB4B-EGLN2 Gene

Variant ID Type Subtype PubMed ID
nsv833832 CNV Loss 17160897
esv26234 CNV Loss 19812545
dgv1084e1 CNV Complex 17122850
nsv521459 CNV Loss 19592680

Relevant External Links for RAB4B-EGLN2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for RAB4B-EGLN2 Gene

Disorders for RAB4B-EGLN2 Gene

Relevant External Links for RAB4B-EGLN2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with RAB4B-EGLN2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAB4B-EGLN2 Gene

Publications for RAB4B-EGLN2 Gene

  1. An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. (PMID: 23026137) Zhu Z. … Gao Y. (Cancer Res. 2012) 2 67
  2. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. (PMID: 22080838) Cho M.H. … . (Hum. Mol. Genet. 2012) 67
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 67
  4. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. (PMID: 20418890) (Nat. Genet. 2010) 67

Products for RAB4B-EGLN2 Gene

Sources for RAB4B-EGLN2 Gene

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