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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB4A Gene

protein-coding   GIFtS: 64
GCID: GC01P229406

RAB4A, member RAS oncogene family


(Previous symbol: RAB4)
 Explore 10 diseases affiliated with
RAB4A via our new
 Human Malady Compendium 
Biological research products
for RAB4A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
RAB4A, Member RAS Oncogene Family1 2
RAB41 2 3 5
HRES-1/RAB41 2
Ras-Related Protein Rab-4A2

External Ids:    HGNC: 97811   Entrez Gene: 58672   Ensembl: ENSG000001681187   OMIM: 1795115   UniProtKB: P203383   

Export aliases for RAB4A gene to outside databases

Previous GC identifers: GC01P227854 GC01P225101 GC01P225807 GC01P226368 GC01P225713 GC01P227473 GC01P199897


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RAB4A:
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane
trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling.
The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane.
Alternatively spliced transcript variants have been observed for this gene. (provided by RefSeq, Dec 2012)

UniProtKB/Swiss-Prot: RAB4A_HUMAN, P20338
Function: Protein transport. Probably involved in vesicular traffic (By similarity)

Gene Wiki entry for RAB4A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB4A gene promoter:
         RORalpha1   LHX3b/Lhx3b   AP-2alpha isoform 3   LHX3a/Lhx3a   AP-2alpha isoform 2   AP-2alpha isoform 4   HNF-3beta   AP-2alpha   RORalpha2   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): RAB4A promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB4A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB4A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42-q43   Ensembl cytogenetic band:  1q42.13   HGNC cytogenetic band: 1q42-q43

RAB4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB4A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P229406:  view genomic region     (about GC identifiers)

Start:
229,406,822 bp from pter      End:
229,441,641 bp from pter
Size:
34,820 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RAB4A_HUMAN, P20338 (See protein sequence)
Recommended Name: Ras-related protein Rab-4A  
Size: 218 amino acids; 24390 Da
Subunit: Interacts with SGSM1, SGSM2 and SGSM3 (By similarity). Interacts with RAB11FIP1, RABEP1, ZFYVE20 and RUFY1.
Interacts (membrane-bound form) with NDRG1; the interaction involves NDRG1 in vesicular recycling of E-cadherin
Subcellular location: Membrane; Peripheral membrane protein. Cytoplasm. Note=Generally associated with membranes.
Cytoplasmic when phosphorylated by CDK1
Caution: It is uncertain whether Met-1 or Met-6 is the initiator
Sequence caution: Sequence=AAA60244.1; Type=Frameshift; Positions=6;
4 PDB 3D structures from and Proteopedia for RAB4A:
1YU9 (3D)        1Z0K (3D)        2BMD (3D)        2BME (3D)    
Secondary accessions: Q5T7P7 Q9BQ44

Explore the universe of human proteins at neXtProt for RAB4A: NX_P20338

Post-translational modifications:

  • Phosphorylated by CDK1 kinase during mitosis1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P20338

  • RAB4A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001258927.1  NP_004569.2  

    ENSEMBL proteins: 
     ENSP00000355651  
    Reactome Protein details: P20338
    Human Recombinant Protein Products: 
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    Uscn Proteins for RAB4A

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005625soluble fraction ----
    GO:0005626insoluble fraction ----
    GO:0005768endosome IEA--
    GO:0005792microsome ----
    GO:0005829cytosol ----


    RAB4A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RAB4A for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type

    Graphical View of Domain Structure for InterPro Entry P20338

    ProtoNet protein and cluster: P20338

    1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB4A_HUMAN, P20338
    Similarity: Belongs to the small GTPase superfamily. Rab family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RAB4A_HUMAN, P20338
    Function: Protein transport. Probably involved in vesicular traffic (By similarity)

    miRNA
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    Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001671ATPase activator activity ----
    GO:0003924GTPase activity IDA15907487
    GO:0005515protein binding IPI19570034
    GO:0005525GTP binding IDA16034420
    GO:0008565protein transporter activity IEA--


    RAB4A for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for RAB4A:
     Decreased cilium length after   Decreased melanin production  Increased S DNA content 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/11 super-pathways (see all 11About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Clathrin-dependent protein traffic
    Clathrin-dependent protein traffic1.00
    wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)0.37
    Transport_Clathrin-coated vesicle cycle0.66
    2Membrane Trafficking
    Membrane Trafficking1.00
    Translocation of GLUT4 to the Plasma Membrane0.32
    3Cytoskeletal Signaling
    Cytoskeletal Signaling1.00
    4Selected targets of ESR1
    Selected targets of ESR11.00
    5Insulin Signaling
    Insulin Signaling1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    2 EMD Millipore Pathways for RAB4A
        Clathrin-dependent protein traffic
    Selected targets of ESR1

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RAB4A
        Epithelial Tight Junctions
    Insulin Receptor Pathway

    1 Cell Signaling Technology (CST) Pathway for RAB4A
        Cytoskeletal Signaling

    4 GeneGo (Thomson Reuters) Pathways for RAB4A
        wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
    Cholesterol and Sphingolipids transport / Influx to the early endosome in lung (normal and CF)
    wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)
    Transport Clathrin-coated vesicle cycle

    2 BioSystems Pathways for RAB4A 
        Insulin Signaling
    Signaling events mediated by TCPTP

    2        Reactome Pathways for RAB4A
        Membrane Trafficking
    Translocation of GLUT4 to the Plasma Membrane


    1         Kegg Pathway  (Kegg details for RAB4A):
        Endocytosis


    RAB4A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAB4A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/46 Interacting proteins for RAB4A (P203381, 2, 3 ENSP000003556514) via UniProtKB, MINT, STRING, and/or I2D (see all 46)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GDI2P503951, 3, ENSP000003695384EBI-722284,EBI-1049143 I2D: score=3 STRING: ENSP00000369538
    TP53P046372, 3MINT-63547 I2D: score=5 
    SRA1Q9HD152, 3MINT-63548 I2D: score=1 
    RAB7AP511492, 3, ENSP000002650624MINT-3369790 I2D: score=1 STRING: ENSP00000265062
    PASKQ96RG22, 3, ENSP000002340404MINT-8148788 I2D: score=1 STRING: ENSP00000234040
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS2501306
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport ----
    GO:0030100regulation of endocytosis IEA--
    GO:0032781positive regulation of ATPase activity ----


    RAB4A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RAB4A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RAB4A
    4 Novoseek chemical compound relationships for RAB4A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gdp 64.1 8 16389071 (3), 9303294 (1), 16413502 (1), 15292453 (1) (see all 5)
    gtp 53.2 6 16389071 (2), 16413502 (2), 9298810 (1), 8858211 (1)
    sodium 0 1 16389071 (1)
    glucose 0 9 9182703 (6), 10320056 (1), 8943343 (1)

    Search CenterWatch for drugs/clinical trials and news about RAB4A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB4A gene (2 alternative transcripts): 
    NM_001271998.1  NM_004578.3  

    Unigene Cluster for RAB4A:

    RAB4A, member RAS oncogene family
    Hs.296169  [show with all ESTs]
    Unigene Representative Sequence: NM_004578
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000481981 ENST00000366690(uc001hth.3) ENST00000473894 ENST00000489342


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    Additional cDNA sequence: 

    AF498934.1 AK223009.1 AK313807.1 AY585832.1 BC002438.1 BC004309.1 BC070287.1 BC107681.1 
    M28211.1 NR_073545.1 

    10 DOTS entries:

    DT.452406  DT.95124080  DT.100709424  DT.91763923  DT.100784308  DT.91848512  DT.121429877  DT.75118334 
    DT.121429879  DT.95124081 

    24/226 AceView cDNA sequences (see all 226):

    CB105949 BI256229 AJ430456 AW082195 AA083507 N74895 CR605031 AI031985 
    BP338704 BC004309 CR617877 AI096456 CB105496 AI203545 NM_006542 CR604401 
    BF475716 AI284948 Z44753 AA810487 F01612 CR602754 AI274226 AW054692 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RAB4A    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c
    SP1:              -                                                               
    SP2:                                                                              
    SP3:                                -                                             
    SP4:        -     -     -           -                                             
    SP5:        -     -     -                                                         


    ECgene alternative splicing isoforms for RAB4A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB4A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGTTTACGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RAB4A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB4A

    SOURCE GeneReport for Unigene cluster: Hs.296169
        SABiosciences Expression via Pathway-Focused PCR Array including RAB4A: 
              Diabetes in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RAB4A gene from 5/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves RAB4A1 RAB4A, member RAS oncogene family 85.17(n)
    98.62(a)
      421532  XM_419573.3  XP_419573.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB4A6
    --
    96(a)
    1 ↔ 1
    1(222126321-222132156)
    African clawed frog
    (Xenopus laevis)
    Amphibia rab4a-prov2 RAB4A, member RAS oncogene family 77.95(n)    BC044974.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc93b032 Danio rerio RAB4A, mRNA (cDNA clone IMAGE6792084) 80.46(n)    BC056535.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab43 RAB small monomeric GTPase 77(a)     --


    ENSEMBL Gene Tree for RAB4A (if available)
    TreeFam Gene Tree for RAB4A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB4A gene
    RAB39A2  RAB252  RAB2A2  RAB142  RAB4B2  RAB39B2  RAB11B2  RAB422  
    RAB11A2  RAB2B2  
    18/86 SIMAP similar genes for RAB4A using alignment to 1 protein entry:     RAB4A_HUMAN(see all similar genes):
    RAB4B    RAB14    RAB2A    DKFZp686J07132    RAB2B    RAB43
    DKFZp313C1541    RAB30    RAB15    RAB11A    RAB13    RAB39B
    RAB8B    RAB19    RAB17    RAB37    RAB33B    RAB5C

    RAB4A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/542 NCBI SNPs in RAB4A are shown (see all 542    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs768439291,2
    F,--229405088(+) TTCATT/CTTCCA 1 -- us2k11Minor allele frequency- C:0.08WA 118
    rs1854195551,2
    --229405098(+) ACAAAC/GTAGAA 1 -- us2k10--------
    rs1903211071,2
    --229405129(+) TGGCAC/GCATAA 1 -- us2k10--------
    rs1144787631,2
    --229405270(+) CTAACG/AAATAG 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs1150133201,2
    C,F,--229405396(+) ATGCAG/CAGAGA 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1137996981,2
    --229405451(+) ATATAC/TAAAAC 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1867302771,2
    --229405524(+) AACTGC/TATTTA 1 -- us2k10--------
    rs557012111,2
    C,F,--229405559(+) AGAAAA/GATACC 1 -- us2k13Minor allele frequency- G:0.11WA CSA 122
    rs1119912371,2
    --229405652(+) ACACAG/AAAGTA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1482878971,2
    --229405818(+) TTTCCC/GATAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RAB4A (229406822 - 229441641 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for RAB4A
         3 CNVs: 74929 66048 84889

    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing RAB4A:
    Pancreatic Cancer
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RAB4A for disorders           About GeneDecksing

    OMIM gene information: 179511    OMIM disorders: --

    10 diseases for RAB4A:    About MalaCards
    becker muscular dystrophy    myelomonocytic leukemia    muscular dystrophy    chronic myelomonocytic leukemia
    insulin resistance    leukemia    breast cancer    cholesterol
    melanoma    pancreatitis


    Export disorders for RAB4A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB4A gene, integrated from 9 sources (see all 95):
    (articles sorted by number of sources associating them with RAB4A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Reversible phosphorylation-dephosphorylation determines the localization of rab4 during the cell cycle. (PubMed id 1425574)1, 2, 9 van der Sluijs P.... Mellman I. (1992)
    2. High resolution crystal structures of human Rab4a in its active and inactive conformations. (PubMed id 15907487)1, 2, 9 Huber S.K. and Scheidig A.J. (2005)
    3. Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes. (PubMed id 11788822)1, 2, 9 de Renzis S.... Zerial M. (2002)
    4. Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein. (PubMed id 11786538)1, 2, 9 Lindsay A.J.... McCaffrey M.W. (2002)
    5. The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a eff ector involved in vesicular recycling of E-cadherin. (PubMed id 17786215)1, 2 Kachhap S.K....Carducci M.A. (2007)
    6. Regulation of CD4 expression via recycling by HRES-1/RAB4 controls susceptibility to HIV infection. (PubMed id 16935861)1, 2 Nagy G.... Perl A. (2006)
    7. Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5. (PubMed id 16034420)1, 2 Eathiraj S.... Lambright D.G. (2005)
    8. Rabip4' is an effector of rab5 and rab4 and regulates transport through early endosomes. (PubMed id 14617813)1, 2 Fouraux M.A.... Pruijn G.J.M. (2004)
    9. Characterisation of the Rab binding properties of Rab coupling protein (RCP) by site-directed mutagenesis. (PubMed id 15280022)1, 2 Lindsay A.J. and McCaffrey M.W. (2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5867 HGNC: 9781 AceView: RAB4A Ensembl:ENSG00000168118 euGenes: HUgn5867
    ECgene: RAB4A Kegg: 5867 H-InvDB: RAB4A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB4A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB4A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB4A gene:
    Search GeneIP for patents involving RAB4A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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