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Aliases for RAB42 Gene

Aliases for RAB42 Gene

  • RAB42, Member RAS Oncogene Family 2 3 5
  • RAB42, Member RAS Homolog Family 2

External Ids for RAB42 Gene

Previous GeneCards Identifiers for RAB42 Gene

  • GC00U906277
  • GC14U900439
  • GC01P028740
  • GC01P028791
  • GC01P028918
  • GC01P027171

Summaries for RAB42 Gene

GeneCards Summary for RAB42 Gene

RAB42 (RAB42, Member RAS Oncogene Family) is a Protein Coding gene. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB39A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB42 Gene

Genomics for RAB42 Gene

Regulatory Elements for RAB42 Gene

Enhancers for RAB42 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RAB42 on UCSC Golden Path with GeneCards custom track

Promoters for RAB42 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RAB42 on UCSC Golden Path with GeneCards custom track

Genomic Location for RAB42 Gene

28,592,200 bp from pter
28,595,443 bp from pter
3,244 bases
Plus strand

Genomic View for RAB42 Gene

Genes around RAB42 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RAB42 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RAB42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB42 Gene

Proteins for RAB42 Gene

  • Protein details for RAB42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative Ras-related protein Rab-42
    Protein Accession:
    Secondary Accessions:
    • B2R5G2

    Protein attributes for RAB42 Gene

    105 amino acids
    Molecular mass:
    11364 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RAB42 Gene

Proteomics data for RAB42 Gene at MOPED

Post-translational modifications for RAB42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAB42 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAB42 Gene

Domains & Families for RAB42 Gene

Gene Families for RAB42 Gene

Protein Domains for RAB42 Gene


Suggested Antigen Peptide Sequences for RAB42 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the small GTPase superfamily. Rab family.
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RAB42: view

Function for RAB42 Gene

Phenotypes for RAB42 Gene

genes like me logo Genes that share phenotypes with RAB42: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RAB42 Gene

Localization for RAB42 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB42 Gene

Membrane; Lipid-anchor.

Subcellular locations from

Jensen Localization Image for RAB42 Gene COMPARTMENTS Subcellular localization image for RAB42 gene
Compartment Confidence
cytosol 3
extracellular 2
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for RAB42 Gene

Pathways & Interactions for RAB42 Gene

SuperPathways for RAB42 Gene

No Data Available

Interacting Proteins for RAB42 Gene

Gene Ontology (GO) - Biological Process for RAB42 Gene


No data available for Pathways by source and SIGNOR curated interactions for RAB42 Gene

Drugs & Compounds for RAB42 Gene

No Compound Related Data Available

Transcripts for RAB42 Gene

mRNA/cDNA for RAB42 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(25) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB42 Gene

RAB42, member RAS oncogene family:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RAB42 Gene

No ASD Table

Relevant External Links for RAB42 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB42 Gene

mRNA expression in normal human tissues for RAB42 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RAB42 Gene

SOURCE GeneReport for Unigene cluster for RAB42 Gene Hs.652321

genes like me logo Genes that share expression patterns with RAB42: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RAB42 Gene

Orthologs for RAB42 Gene

This gene was present in the common ancestor of animals.

Orthologs for RAB42 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RAB42 35
  • 86.85 (n)
  • 83.03 (a)
RAB42 36
  • 38 (a)
(Canis familiaris)
Mammalia RAB42 35
  • 88.84 (n)
  • 87.16 (a)
RAB42 36
  • 40 (a)
(Mus musculus)
Mammalia Rab42 35
  • 83.72 (n)
  • 79.53 (a)
Rab42 16
Rab42 36
  • 36 (a)
(Pan troglodytes)
Mammalia RAB42 35
  • 99.85 (n)
  • 99.54 (a)
RAB42 36
  • 99 (a)
(Monodelphis domestica)
Mammalia RAB42 36
  • 30 (a)
(Gallus gallus)
Aves RAB42 36
  • 22 (a)
(Danio rerio)
Actinopterygii rab42a 36
  • 18 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rab39 36
  • 15 (a)
(Caenorhabditis elegans)
Secernentea rab-39 36
  • 16 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 18 (a)
Species with no ortholog for RAB42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RAB42 Gene

Gene Tree for RAB42 (if available)
Gene Tree for RAB42 (if available)

Paralogs for RAB42 Gene

(23) SIMAP similar genes for RAB42 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RAB42: view

Variants for RAB42 Gene

Sequence variations from dbSNP and Humsavar for RAB42 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs4654310 -- 28,591,407(+) ctggg(C/T)gacag upstream-variant-2KB
rs4654341 -- 28,594,687(+) CCTTG(A/C)AGGGA downstream-variant-500B
rs9426285 -- 28,590,743(+) TGAGA(C/T)GGAGT upstream-variant-2KB
rs12069148 -- 28,593,360(+) cacca(C/T)gcccg intron-variant
rs11800899 -- 28,592,015(+) AGGCC(A/G)GGGCT upstream-variant-2KB

Variation tolerance for RAB42 Gene

Residual Variation Intolerance Score: 57.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.44; 28.24% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for RAB42 Gene

Disorders for RAB42 Gene

Relevant External Links for RAB42

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RAB42 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAB42 Gene

Publications for RAB42 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for RAB42 Gene

Sources for RAB42 Gene