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Aliases for RAB42 Gene

Aliases for RAB42 Gene

  • RAB42, Member RAS Oncogene Family 2 3
  • RAB42, Member RAS Homolog Family 2

External Ids for RAB42 Gene

Summaries for RAB42 Gene

GeneCards Summary for RAB42 Gene

RAB42 (RAB42, Member RAS Oncogene Family) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAB39A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB42 Gene

Genomics for RAB42 Gene

Genomic Location for RAB42 Gene

Start:
28,592,200 bp from pter
End:
28,595,443 bp from pter
Size:
3,244 bases
Orientation:
Plus strand

Genomic View for RAB42 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB42 Gene

Regulatory Elements for RAB42 Gene

Proteins for RAB42 Gene

  • Protein details for RAB42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4Z0-RAB42_HUMAN
    Recommended name:
    Putative Ras-related protein Rab-42
    Protein Accession:
    Q8N4Z0
    Secondary Accessions:
    • B2R5G2

    Protein attributes for RAB42 Gene

    Size:
    105 amino acids
    Molecular mass:
    11364 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RAB42 Gene

Proteomics data for RAB42 Gene at MOPED

Post-translational modifications for RAB42 Gene

No Post-translational modifications

Other Protein References for RAB42 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAB42 Gene

Domains for RAB42 Gene

Gene Families for RAB42 Gene

HGNC:
  • RAB :RAB, member RAS oncogene

Protein Domains for RAB42 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

RAB42_HUMAN
Family:
  • Belongs to the small GTPase superfamily. Rab family.:
    • Q8N4Z0
genes like me logo Genes that share domains with RAB42: view

Function for RAB42 Gene

Gene Ontology (GO) - Molecular Function for RAB42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity IBA --
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with RAB42: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RAB42 Gene

Localization for RAB42 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB42 Gene

Membrane; Lipid-anchor.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RAB42 Gene COMPARTMENTS Subcellular localization image for RAB42 gene
Compartment Confidence
cytosol 3
extracellular 2
nucleus 1

Gene Ontology (GO) - Cellular Components for RAB42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IBA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with RAB42: view

Pathways for RAB42 Gene

SuperPathways for RAB42 Gene

No Data Available

Interacting Proteins for RAB42 Gene

Gene Ontology (GO) - Biological Process for RAB42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006886 intracellular protein transport IBA --
GO:0007264 small GTPase mediated signal transduction --
GO:0008152 metabolic process IBA --
GO:0015031 protein transport --
GO:0032482 Rab protein signal transduction IBA --
genes like me logo Genes that share ontologies with RAB42: view

No data available for Pathways by source for RAB42 Gene

Transcripts for RAB42 Gene

mRNA/cDNA for RAB42 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(25) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB42 Gene

RAB42, member RAS oncogene family:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RAB42 Gene

No ASD Table

Relevant External Links for RAB42 Gene

GeneLoc Exon Structure for
RAB42
ECgene alternative splicing isoforms for
RAB42

Expression for RAB42 Gene

mRNA expression in normal human tissues for RAB42 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for RAB42 Gene

SOURCE GeneReport for Unigene cluster for RAB42 Gene Hs.652321

genes like me logo Genes that share expressions with RAB42: view

Orthologs for RAB42 Gene

This gene was present in the common ancestor of animals.

Orthologs for RAB42 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RAB42 36
  • 99.85 (n)
  • 99.54 (a)
RAB42 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RAB42 36
  • 86.85 (n)
  • 83.03 (a)
RAB42 37
  • 38 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RAB42 36
  • 88.84 (n)
  • 87.16 (a)
RAB42 37
  • 40 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rab42 36
  • 83.72 (n)
  • 79.53 (a)
Rab42 16
Rab42 37
  • 36 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RAB42 37
  • 30 (a)
OneToOne
chicken
(Gallus gallus)
Aves RAB42 37
  • 22 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii rab42a 37
  • 18 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Rab39 37
  • 15 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea rab-39 37
  • 16 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 18 (a)
OneToMany
Species with no ortholog for RAB42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RAB42 Gene

ENSEMBL:
Gene Tree for RAB42 (if available)
TreeFam:
Gene Tree for RAB42 (if available)

Paralogs for RAB42 Gene

Selected SIMAP similar genes for RAB42 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RAB42: view

Variants for RAB42 Gene

Sequence variations from dbSNP and Humsavar for RAB42 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs4654310 -- 28,591,407(+) ctggg(C/T)gacag upstream-variant-2KB
rs4654341 -- 28,594,687(+) CCTTG(A/C)AGGGA downstream-variant-500B
rs9426285 -- 28,590,743(+) TGAGA(C/T)GGAGT upstream-variant-2KB
rs11800899 -- 28,592,015(+) AGGCC(A/G)GGGCT upstream-variant-2KB
rs12065373 -- 28,594,083(+) CCCCA(A/G)CAGGA missense, reference

Relevant External Links for RAB42 Gene

HapMap Linkage Disequilibrium report
RAB42

No data available for Structural Variations from Database of Genomic Variants (DGV) for RAB42 Gene

Disorders for RAB42 Gene

No disorders were found for RAB42 Gene.

No data available for UniProtKB/Swiss-Prot for RAB42 Gene

Publications for RAB42 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for RAB42 Gene

Sources for RAB42 Gene

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