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RAB3IP Gene

protein-coding   GIFtS: 51
GCID: GC12P070132

RAB3A Interacting Protein

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB3A Interacting Protein1 2     Rab-3A-Interacting Protein2
Rab3A-Interacting Protein2 3     rabin-32
SSX2-Interacting Protein2 3     SSX2 Interacting Protein2
rabin31     RABIN83
RABIN32     Rabin-33

External Ids:    HGNC: 165081   Entrez Gene: 1171772   Ensembl: ENSG000001273287   OMIM: 6086865   UniProtKB: Q96QF03   

Export aliases for RAB3IP gene to outside databases

Previous GC identifers: GC00U991125 GC12U900020 GC12P069849 GC12P068418 GC12P067181


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB3IP Gene:
RAB3IP (RAB3A interacting protein) is a protein-coding gene. GO annotations related to this gene include Rab guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAB3IL1.

UniProtKB/Swiss-Prot: RAB3I_HUMAN, Q96QF0
Function: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of
GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of
GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized
transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex,
PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites
(AMIS), apical surface formation and lumenogenesis

Gene Wiki entry for RAB3IP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB3IP gene promoter:
         POU2F1   HOXA3   POU2F1a   STAT5A   E4BP4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB3IP promoter sequence
   Search Chromatin IP Primers for RAB3IP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB3IP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q15   Ensembl cytogenetic band:  12q15   HGNC cytogenetic band: 12q15

RAB3IP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB3IP gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P070132:  view genomic region     (about GC identifiers)

Start:
70,132,461 bp from pter      End:
70,216,984 bp from pter
Size:
84,524 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAB3I_HUMAN, Q96QF0 (See protein sequence)
Recommended Name: Rab-3A-interacting protein  
Size: 476 amino acids; 53021 Da
Subunit: Interacts with the N-terminal region of SSX2. Interacts with the GDP-bound forms of RAB3A, RAB3D, RAB8A
and RAB8B
3 PDB 3D structures from and Proteopedia for RAB3IP:
4LHX (3D)        4LHY (3D)        4LHZ (3D)    
Secondary accessions: B7WPJ6 Q6PCE4 Q96A24 Q96QE6 Q96QE7 Q96QE8 Q96QE9 Q96QF1 Q9H673
Alternative splicing: 8 isoforms:  Q96QF0-1   Q96QF0-2   Q96QF0-3   Q96QF0-4   Q96QF0-5   Q96QF0-6   Q96QF0-7   Q96QF0-8   
(No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAB3IP: NX_Q96QF0

Explore proteomics data for RAB3IP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB3IP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001019818.1  NP_001265331.1  NP_071901.2  NP_783322.1  NP_783323.1  NP_783324.1  

    ENSEMBL proteins: 
     ENSP00000247833   ENSP00000368092   ENSP00000419216   ENSP00000436304   ENSP00000450355  
     ENSP00000447300   ENSP00000368086   ENSP00000355381   ENSP00000448944   ENSP00000447499  
     ENSP00000448218   ENSP00000448688   ENSP00000448773   ENSP00000448027   ENSP00000432634  
     ENSP00000448102   ENSP00000323349  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009449 Sec2p

    Graphical View of Domain Structure for InterPro Entry Q96QF0

    ProtoNet protein and cluster: Q96QF0

    UniProtKB/Swiss-Prot: RAB3I_HUMAN, Q96QF0
    Similarity: Belongs to the SEC2 family


    Find genes that share domains with RAB3IP           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB3I_HUMAN, Q96QF0
    Function: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of
    GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of
    GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized
    transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex,
    PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites
    (AMIS), apical surface formation and lumenogenesis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12007189
    GO:0017112Rab guanyl-nucleotide exchange factor activity IDA--
         
    Find genes that share ontologies with RAB3IP           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RAB3IP:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rab3ip):
     normal 

    Find genes that share phenotypes with RAB3IP           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB3IP
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    hsa-mir-484 (MIRT042106), hsa-mir-182-5p (MIRT047202)

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    Selected qRT-PCR Assays for microRNAs that regulate RAB3IP (see all 41):
    hsa-miR-124* hsa-miR-330-5p hsa-miR-4328 hsa-miR-3923 hsa-miR-326 hsa-miR-186 hsa-miR-509-3-5p hsa-miR-181b
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    Addgene plasmids for RAB3IP 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB3I_HUMAN, Q96QF0: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cell projection, lamellipodium.
    Note=Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein
    kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical
    actin
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol5
    nucleus5
    golgi apparatus1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12007189
    GO:0005813centrosome IDA17574030
    GO:0005829cytosol IDA12007189
    GO:0005856cytoskeleton IEA--
    GO:0030027lamellipodium IEA--

    Find genes that share ontologies with RAB3IP           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB3IP
    Interactions:

        GeneGlobe Interaction Network for RAB3IP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB3IP (Q96QF01, 2, 3 ENSP000003680864) via UniProtKB, MINT, STRING, and/or I2D (see all 120)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB3IL1Q8TBN01, 2, 3EBI-747844,EBI-743796 MINT-67161 I2D: score=4 
    SSX2BQ163851, 3EBI-747865,EBI-2210673 I2D: score=2 
    SSX2Q163851, 3, ENSP000003387964EBI-747865,EBI-2210673 I2D: score=2 STRING: ENSP00000338796
    RAB8AP610063, ENSP000003009354I2D: score=2 STRING: ENSP00000300935
    RAB3AP203363, ENSP000002222564I2D: score=2 STRING: ENSP00000222256
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006893Golgi to plasma membrane transport TAS17574030
    GO:0015031protein transport IEA--
    GO:0032313regulation of Rab GTPase activity IDA--
    GO:0033365protein localization to organelle IMP17574030
    GO:0042384cilium assembly IMP17574030

    Find genes that share ontologies with RAB3IP           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB3IP (RAB3I)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB3IP gene (8 alternative transcripts): 
    NM_175626.1  NM_175627.1  NM_001024647.3  NM_001278402.1  NM_022456.4  NM_175623.3  NM_175624.3  NM_175625.3  

    Unigene Cluster for RAB3IP:

    RAB3A interacting protein
    Hs.258209  [show with all ESTs]
    Unigene Representative Sequence: NM_175623
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000247833 ENST00000378815(uc021rao.1) ENST00000483530 ENST00000417413
    ENST00000549760 ENST00000550536(uc001svm.3 uc001svn.3 uc001svo.3 uc001svp.3 uc001svq.3 uc001svs.3 uc001svt.3)
    ENST00000378809 ENST00000362025 ENST00000552199 ENST00000547591 ENST00000550647
    ENST00000547055 ENST00000551641 ENST00000553099 ENST00000526994 ENST00000550847
    ENST00000481897 ENST00000552610
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    Selected qRT-PCR Assays for microRNAs that regulate RAB3IP (see all 41):
    hsa-miR-124* hsa-miR-330-5p hsa-miR-4328 hsa-miR-3923 hsa-miR-326 hsa-miR-186 hsa-miR-509-3-5p hsa-miR-181b
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      QuantiTect SYBR Green Assays in human, mouse, rat RAB3IP
      QuantiFast Probe-based Assays in human, mouse, rat RAB3IP

    Additional mRNA sequence: 

    AJ312896.1 AJ312897.1 AJ312898.1 AJ312899.1 AK026201.1 AK027566.1 AK027671.1 AK057844.1 
    AK123728.1 AK225441.1 AK314547.1 AY685922.1 BC014553.2 BC015548.1 BC039421.1 BC059358.1 
    BX537658.1 

    13 DOTS entries:

    DT.92443667  DT.302527  DT.97808259  DT.100774128  DT.99955221  DT.99976520  DT.95171517  DT.100774126 
    DT.92034033  DT.121188114  DT.97773063  DT.100720318  DT.121188052 

    Selected AceView cDNA sequences (see all 157):

    AI283079 AI393299 AI680670 BC015548 BF436325 AL713462 BF590473 BF515827 
    AA809950 AA922926 CR607211 AI654813 AV654488 AW292126 CB105555 BU608062 
    BP371116 BF095791 BM458766 AJ312896 BM554898 BX107864 BM711029 NM_175624 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RAB3IP (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13
    SP1:        -                 -     -     -                                   -                     
    SP2:                          -     -     -                                   -                     
    SP3:                          -     -     -                                   -     -               
    SP4:                          -     -     -                       -     -     -                     
    SP5:                                      -                                   -                     


    ECgene alternative splicing isoforms for RAB3IP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB3IP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTCTTTTA
    RAB3IP Expression
    About this image

    RAB3IP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB3IP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.258209

    UniProtKB/Swiss-Prot: RAB3I_HUMAN, Q96QF0
    Tissue specificity: Expressed in brain, kidney, heart, pancreas and placenta. Not detected in skeletal muscle or
    liver

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB3IP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB3IP gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab3ip1 , 5 RAB3A interacting protein1, 5 84.97(n)1
    89.95(a)1
      10 (64.96 cM)5
    2163631  NM_001003950.21  NP_001003950.11 
     1169057845 
    chicken
    (Gallus gallus)
    Aves RAB3IP1 RAB3A interacting protein (rabin3) 82.08(n)
    86.08(a)
      417850  XM_004937566.1  XP_004937623.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    79(a)
    1 → many
    GL343256.1(1716564-1749274)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC054310.12   -- 77.21(n)    BC054310.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.116912 Transcribed sequence with moderate similarity to protein more 75.78(n)    57086952 
    worm
    (Caenorhabditis elegans)
    Secernentea F54C9.116
    Protein F54C9.11 (F54C9.11) mRNA, complete cds
    28(a)
    1 → many
    II(8583030-8585050) WBGene00010045


    ENSEMBL Gene Tree for RAB3IP (if available)
    TreeFam Gene Tree for RAB3IP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB3IP gene
    RAB3IL12  ENSG000002580522  
    1 SIMAP similar gene for RAB3IP using alignment to 8 protein entries:     RAB3I_HUMAN (see all proteins):
    RAB3IL1

    Find genes that share paralogs with RAB3IP           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB3IP (see all 1765)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1392239441,2
    --70130668(+) CTTCTC/TAAACA 2 -- us2k10--------
    rs1893919981,2
    --70130742(+) GGTAGA/GTGATT 2 -- us2k10--------
    rs1427715461,2
    --70130751(+) TTTGTA/CAATGG 2 -- us2k10--------
    rs1473826651,2
    --70130775(+) TCAGGC/TATATA 2 -- us2k10--------
    rs1814856821,2
    --70130827(+) GTCTTA/TTGTAG 2 -- us2k10--------
    rs754357171,2
    C,F--70130927(+) CAGTCC/TTACTG 2 -- us2k12Minor allele frequency- T:0.04WA 120
    rs1150978141,2
    F--70131081(+) GGAGTG/AGCTGG 2 -- us2k11Minor allele frequency- A:0.03WA 118
    rs2002325621,2
    C--70131088(-) CCCTAC/TCCCAG 2 -- us2k10--------
    rs1113436721,2
    C,F--70131196(+) ATCAAG/AACATA 4 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1866043981,2
    --70131330(+) CTATAC/TATGTT 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for RAB3IP (70132461 - 70216984 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RAB3IP:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746020CNV Deletion23290073
    esv1958700CNV Deletion18987734
    nsv52529CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB3IP
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608686    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RAB3IP:
    Pilocytic astrocytoma

    Find genes that share disorders with RAB3IP           About GenesLikeMe


    Export disorders for RAB3IP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB3IP gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with RAB3IP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. (PubMed id 12007189)1, 2, 9 de Bruijn D.R.H....van Kessel A.G. (Genes Chromosomes Cancer 2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport. (PubMed id 12221131)1, 2 Hattula K.... Peranen J. (Mol. Biol. Cell 2002)
    5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    6. A molecular network for de novo generation of the apical surface and lumen. (PubMed id 20890297)2 Bryant D.M.... Mostov K.E. (Nat. Cell Biol. 2010)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    8. Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. (PubMed id 20937701)2 Yoshimura S.... Barr F.A. (J. Cell Biol. 2010)
    9. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 117177 HGNC: 16508 AceView: RAB3IP Ensembl:ENSG00000127328 euGenes: HUgn117177
    ECgene: RAB3IP H-InvDB: RAB3IP

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB3IP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB3IP gene:
    Search GeneIP for patents involving RAB3IP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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