V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

RAB3GAP1 Gene

protein-coding GIFtS: 51

GC02P135526

RAB3 GTPase activating protein subunit 1 (catalytic)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DKFZp434A012 ^²
KIAA0066 ^¹, ², ³
P130 ^², ⁵
RAB3GAP ^¹, ², ³
RAB3GAP130 ^¹, ²
Rab3-GAP ^³
WARBM1 ^¹, ², ⁵

Descriptions
RAB3 GTPase activating protein subunit 1 (catalytic) ^²
RAB3 GTPase-activating protein ^²
RAB3 GTPase-activating protein 130 kDa subunit ^³
Rab3-GAP p130 ^³

External Ids
HGNC: 17063¹
Entrez Gene: 22930²
UniProtKB: Q15042³
Ensembl: ENSG00000115839⁷

Search outside databases for aliases for RAB3GAP1 gene

Previous GC identifers: GC02P135645 GC02U900802

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for RAB3GAP1:

Members of the RAB3 protein family (see RAB3A; MIM 179490) are implicated in regulated exocytosis

of neurotransmitters and hormones. RAB3GAP, which is involved in regulation of RAB3 activity, is a

heterodimeric complex consisting a 130-kD catalytic subunit and a 150-kD noncatalytic subunit (MIM

609275). RAB3GAP specifically converts active RAB3-GTP to the inactive form RAB3-GDP (Aligianis et

al., 2005 [PubMed 15696165]).[supplied by OMIM]

UniProtKB/Swiss-Prot: RB3GP_HUMAN, Q15042

Function: Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3

subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of

neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form

Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental

processes such as proliferation, migration and differentiation before synapse formation, and

non-synaptic vesicular release of neurotransmitters

Gene Wiki entry for RAB3GAP1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the RAB3GAP1 gene

Entrez Gene cytogenetic band: 2q21.3 Ensembl cytogenetic band: 2q21.3 HGNC cytogenetic band: 2q21.3

RAB3GAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P135526: (about GC identifiers)

Start:	135,526,323 bp from pter
End:	135,644,048 bp from pter
Size:	117,726 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000002.10 NT_022135.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: RB3GP_HUMAN, Q15042 (See protein sequence)

Recommended Name: Rab3 GTPase-activating protein catalytic subunit

Size: 981 amino acids; 110524 Da

Subunit: The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150.

The Rab3 GTPase-activating complex interacts with DMXL2 (By similarity)

Subcellular location: Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction

Secondary accessions: Q659F5 Q8TBB4

Alternative splicing: 2 isoforms: Q15042-1 Q15042-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_036365.1

ENSEMBL proteins:

ENSP00000264158 ENSP00000364996

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (RAB3GAP1)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005625	soluble fraction	IDA	9852129
GO:0005737	cytoplasm	IEA	--

About this table

Antibodies for RAB3GAP1:

	Invitrogen Antibodies for RAB3GAP1
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (RAB3GAP1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for RAB3GAP1

Assays for RAB3GAP1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q15042

UniProtKB/Swiss-Prot: RB3GP_HUMAN, Q15042

Similarity: Belongs to the Rab3-GAP catalytic subunit family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RAB3GAP1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012233

Applied Biosystems Silencer® siRNAs for RAB3GAP1

Sigma-Aldrich siRNA for RAB3GAP1

Sigma-Aldrich shRNA for RAB3GAP1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_012233
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012233
untagged cDNA clone in CMV expression vector: NM_012233

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_012233

UniProtKB/Swiss-Prot: RB3GP_HUMAN, Q15042

Function: Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3

subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of

neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form

Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental

processes such as proliferation, migration and differentiation before synapse formation, and

non-synaptic vesicular release of neurotransmitters

Biophysicochemical properties: Kinetic parameters: KM=75 uM for GTP-loaded RAB3A;

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Rab3gap1):

nervous system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005096	GTPase activator activity	IEA	--
GO:0005097	Rab GTPase activator activity	IDA	9030515 10859313
GO:0017137	Rab GTPase binding	IPI	10859313

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for RAB3GAP1

5/8 Interacting proteins for RAB3GAP1 (ENSP00000264158³) via UniProtKB, MINT, and/or STRING (see all 8 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RAB3GAP2	ENSP00000351832³	STRING (score=.983)
RAB3A	ENSP00000222256³	STRING (score=.879)
DMXL2	ENSP00000251076³	STRING (score=.85)
RAB3B	ENSP00000360718³	STRING (score=.75)
RAB3D	ENSP00000222120³	STRING (score=.75)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0043087	regulation of GTPase activity	IDA	10859313

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for RAB3GAP1

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for RAB3GAP1
2 Novoseek chemical compound relationships for RAB3GAP1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
gdp	72.31	7	12786944 (1), 9852129 (1), 16473606 (1), 11809763 (1)
gtp	65.95	8	9224661 (1), 12786944 (1), 9852129 (1), 16473606 (1) (see all 5)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RAB3GAP1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012233

Sigma-Aldrich siRNA for RAB3GAP1

Sigma-Aldrich shRNA for RAB3GAP1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012233

REFSEQ mRNAs for RAB3GAP1 gene:

NM_012233.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012233

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_012233
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_012233
                                 untagged cDNA clone in CMV expression vector: NM_012233

Additional cDNA sequence:

AB449877.1 AK022494.1 AK056058.1 AK309118.1 AL096752.1 BC020303.1 BC022977.1 BC030992.2

BC036732.1 BC071602.1 BC146809.1 D31886.1

19 DOTS entries:

DT.318550 DT.92042000 DT.100765793 DT.100692986 DT.120977449 DT.92432825 DT.318552 DT.92432826

DT.97826377 DT.91863266 DT.120977404 DT.120977412 DT.95276239 DT.120977398 DT.91690664 DT.95276242

DT.120977492 DT.91751690 DT.91986408

highest scoring ESTs for RAB3GAP1:

AL096752 D31886 AA126453 AA135529 AA216018 AA363190 AA370959 AA385533 AA429718 AA442748

Unigene Cluster for RAB3GAP1:

RAB3 GTPase activating protein subunit 1 (catalytic)

Hs.306327 [show with all ESTs]

Unigene Representative Sequence: BC071602

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RAB3GAP1 (see all 8 )

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	^	10a	·	10b	^	11a	·	11b	^	12	^	13	^	14a	·	14b	^	15a	·	15b	^	16
SP1:
SP2:							-
SP3:
SP4:
SP5:																																			-

About this scheme

ECgene alternative splicing isoforms for RAB3GAP1

2 Ensembl transcripts including schematic representations:

ENST00000264158 ENST00000375836

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

RAB3GAP1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for RAB3GAP1

¹ / ² / ³

11 probe-sets matching RAB3GAP1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33417_at²^{, 3}	U95-A	1	1.00	1.00	0.68	0.87	D31886	0.80	0.88	0.84	1
33418_at²^{, 3}	U95-A	1	0.56	1.00	0.64	1.04	AL096752	0.80	1.00	0.91	1
82678_at*²^{, 3}	U95-D	1	0.94	1.00	0.86	1.09	R99109	0.20	1.00	0.72	1
212932_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AK022494	0.60	0.83	0.73	1
213531_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI040009	0.40	1.00	0.76	1
213530_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI040009	0.40	1.00	0.76	1
239527_at*²^{, 3}	U133-B	2	0.73	0.94	--	--	BF103605	0.20	1.00	0.72	1
212932_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
213531_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
213530_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
239527_at*²	U133Plus2	2	0.73	0.94	--	--	--	--	--	--	--

GeneDecks RAB3GAP1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GAGCTCAAGA

SOURCE GeneReport for Unigene cluster: Hs.306327
UniProtKB/Swiss-Prot: RB3GP_HUMAN, Q15042
Tissue specificity: Ubiquitous

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for RAB3GAP1 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	RAB3GAP1¹	--	RAB3 GTPase activating protein subunit 1 (catalytic)	92.81(n) 94.99(a)	476127 XM_851254.1 XP_856347.1
chimpanzee (Pan troglodytes)	RAB3GAP1¹	--	RAB3 GTPase activating protein subunit 1 (catalytic)	99.63(n) 99.69(a)	470548 XM_001153005.1 XP_001153005.1
cow (Bos taurus)	RAB3GAP1¹	--	RAB3 GTPase activating protein subunit 1 (catalytic)	91.98(n) 95.21(a)	535393 XM_615469.3 XP_615469.3
mouse (Mus musculus)	Rab3gap1^{1, 5}	1⁵	RAB3 GTPase activating protein subunit 1^{1, 5}	87.01(n)¹ 92.95(a)¹	226407¹ NM_178690.3¹ NP_848805.1¹ AI835577⁵ AK035603⁵ (see all 24)
chicken (Gallus gallus)	RAB3GAP1¹	--	RAB3 GTPase activating protein subunit 1 (catalytic)	80.16(n) 87.19(a)	424290 XM_422135.2 XP_422135.2

About this table Species with no ortholog for RAB3GAP1

ENSEMBL Gene Tree for RAB3GAP1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/495 NCBI SNPs in RAB3GAP1 are shown (see all 495 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 92)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10445686^1,2	C,F,H	135609842(+)	`AGGAAA/GTGGAC`	1	N/S	mis¹		8		EU EA WA	838
--	rs7424356^1,2	A,C	135525711(+)	`gatcgC/Tgccac`	1	--	ng5¹		0	--	--	--	--
	rs16831395^1,2	F,H	135643898(+)	`TCTTAT/CTTTTA`	1	--	ut3¹		7		NA EU EA WA	562
--	rs10170125^1,2	C,F	135642956(+)	`AGCATC/GGGAAA`	1	--	ut3¹ ese³		3		NA	142
	rs13390850^1,2	H	135525827(+)	`TCCCAG/AAAACC`	1	--	ng5¹ tfbs³		4		EU EA WA	418
	rs7595725^1,2	A,F,H	135624477(+)	`ACATCG/AGCAGA`	1	S/S	syn¹ ese³		4		EU EA WA	418
	rs17261772^1,2	C,F,H	135627892(+)	`CTCTTC/TGATGA`	1	F/F	syn¹		9		NA EU EA WA	744
	rs1869829^1,2	A,C,F,H,O	135594032(-)	`ATTAAC/TGAATC`	1	--	int¹		21		NS EU EA WA NA	1520
--	rs9287439^1,2	A,C,F,H	135586231(+)	`GACCTC/TAAACT`	1	--	int¹		12		EU EA WA NS NA	656
	rs7594509^1,2	A,C,F,H	135629447(+)	`aatatG/Tcaatt`	1	--	int¹		4		EU EA WA	418

About this table

HapMap Linkage Disequilibrium images for RAB3GAP1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602536 disorders: 600118

UniProtKB/Swiss-Prot: RB3GP_HUMAN, Q15042

Defects in RAB3GAP1 are the cause of Warburg micro syndrome 1 (WARBM1) [MIM:600118].

WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of

the eye and central nervous system and by microgenitalia

Human Gene Mutation Database: RAB3GAP1

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/27 PubMed articles for RAB3GAP1 gene (see all 27 ):

Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome. (PubMed id 15696165)^{1, 2, 3, 4} Aligianis I.A....Maher E.R. (2005)
Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins. (PubMed id 9030515)^{1, 2, 3, 4} Fukui K.... Takai Y. (1997)
Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP. (PubMed id 10859313)^{1, 3, 4} Clabecq A.... Darchen F. (2000)
Localization of the Rab3 small G protein regulators in nerve terminals and their involvement in Ca2+-dependent exocytosis. (PubMed id 9852129)^{1, 3, 4} Oishi H.... Takai Y. (1998)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)^{3, 4} Nomura N....Tabata S. (1994)
A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)- dependent exocytosis of neurotransmitter. (PubMed id 12786944)^{1, 3} Kawabe H.... Takai Y. (2003)
Phenotypic variability in Micro syndrome: report of new cases. (PubMed id 18286824)^{1, 3} Abdel-Salam G.M....Aligianis I.A. (2007)
Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. (PubMed id 19077034)³ Ishibashi K.... Fukuda M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 22930	HGNC: 17063	Ensembl:ENSG00000115839	euGenes: HUgn22930	ECgene: RAB3GAP1
H-InvDB: RAB3GAP1

(According to HUGE)
About This Section

HUGE: KIAA0066

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
GeneReviews	http://www.genetests.org/query?gene=RAB3GAP1

Licensable Technologies for RAB3GAP1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for RAB3GAP1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for RAB3GAP1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for RAB3GAP1		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for RAB3GAP1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Search for Antibodies
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (RAB3GAP1)
	Antibodies (RAB3GAP1)

Search OriGene for RAB3GAP1

Search Tocris compounds for RAB3GAP1

	Drugs for RAB3GAP1
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for RAB3GAP1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
RAB3GAP1 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

RAB3GAP1 Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for RAB3GAP1

Summaries
for RAB3GAP1

Genomic Location
for RAB3GAP1

Proteins
for RAB3GAP1

Protein Domains/
Families
for RAB3GAP1

Gene Function
for RAB3GAP1

Pathways & Interactions
for RAB3GAP1

Drugs & Compounds
for RAB3GAP1

Transcripts
for RAB3GAP1

Expression
for RAB3GAP1

Orthologs
for RAB3GAP1

Paralogs
for RAB3GAP1

SNPs/Variants
for RAB3GAP1

Disorders & Mutations
for RAB3GAP1

Medical News
for RAB3GAP1

Publications
for RAB3GAP1

Search for RAB3GAP1

Genome Databases showing RAB3GAP1

Other Databases showing RAB3GAP1

Specialized Databases showing RAB3GAP1

Licensable Technologies
for RAB3GAP1

Services
for RAB3GAP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

RAB3GAP1 Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor RAB3GAP1

Summariesfor RAB3GAP1

Genomic Locationfor RAB3GAP1

Proteinsfor RAB3GAP1

Protein Domains/Familiesfor RAB3GAP1

Gene Functionfor RAB3GAP1

Pathways & Interactionsfor RAB3GAP1

Drugs & Compoundsfor RAB3GAP1

Transcriptsfor RAB3GAP1

Expression for RAB3GAP1

Orthologsfor RAB3GAP1

Paralogsfor RAB3GAP1

SNPs/Variantsfor RAB3GAP1

Disorders & Mutationsfor RAB3GAP1

Medical Newsfor RAB3GAP1

Publicationsfor RAB3GAP1

Search for RAB3GAP1

Genome Databases showing RAB3GAP1

Other Databases showing RAB3GAP1

Specialized Databases showing RAB3GAP1

Licensable Technologiesfor RAB3GAP1

Servicesfor RAB3GAP1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for RAB3GAP1

Summaries
for RAB3GAP1

Genomic Location
for RAB3GAP1

Proteins
for RAB3GAP1

Protein Domains/
Families
for RAB3GAP1

Gene Function
for RAB3GAP1

Pathways & Interactions
for RAB3GAP1

Drugs & Compounds
for RAB3GAP1

Transcripts
for RAB3GAP1

Expression
for RAB3GAP1

Orthologs
for RAB3GAP1

Paralogs
for RAB3GAP1

SNPs/Variants
for RAB3GAP1

Disorders & Mutations
for RAB3GAP1

Medical News
for RAB3GAP1

Publications
for RAB3GAP1

Licensable Technologies
for RAB3GAP1

Services
for RAB3GAP1