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RAB3D Gene

protein-coding   GIFtS: 56
GCID: GC19M011435

RAB3D, Member RAS Oncogene Family


(Previous symbol: GOV)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB3D, Member RAS Oncogene Family1 2     RAB162 3
GOV1 2 3 5     RAD3D2 5
Glioblastoma Overexpressed1 2     D2-22
Rab3D Upregulated With Myeloid Differentiation1 2     Ras-Related Protein Rab-3D2

External Ids:    HGNC: 97791   Entrez Gene: 95452   Ensembl: ENSG000001055147   OMIM: 6043505   UniProtKB: O957163   

Export aliases for RAB3D gene to outside databases

Previous GC identifers: GC19M011566 GC19M011655 GC19M011280 GC19M011296 GC19M011008


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB3D Gene:
RAB3D (RAB3D, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB3D include tumor of exocrine pancreas, and esophageal varix. GO annotations related to this gene include GTPase binding and GTP binding. An important paralog of this gene is RAB10.

UniProtKB/Swiss-Prot: RAB3D_HUMAN, O95716
Function: Protein transport. Probably involved in regulated exocytosis (By similarity)

Gene Wiki entry for RAB3D Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RAB3D gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   Egr-4   c-Ets-1   HEN1   E2F   E2F-1   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB3D promoter sequence
   Search Chromatin IP Primers for RAB3D

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB3D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2

RAB3D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB3D gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M011435:  view genomic region     (about GC identifiers)

Start:
11,432,722 bp from pter      End:
11,456,946 bp from pter
Size:
24,225 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RAB3D_HUMAN, O95716 (See protein sequence)
Recommended Name: Ras-related protein Rab-3D  
Size: 219 amino acids; 24267 Da
Subunit: Interacts with RIMS1, RIMS2, RPH3A, RPH3AL and RAB3IP (By similarity)
1 PDB 3D structure from and Proteopedia for RAB3D:
2GF9 (3D)    

Explore the universe of human proteins at neXtProt for RAB3D: NX_O95716

Explore proteomics data for RAB3D at MOPED


See RAB3D Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_004274.1  
ENSEMBL proteins: 
 ENSP00000222120   ENSP00000466000  

RAB3D Human Recombinant Protein Products:

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Abcam antibodies for RAB3D (O95716, P20336)
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LSBio Antibodies in human, mouse, rat for RAB3D

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Cloud-Clone Corp. CLIAs for RAB3D


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
RAB: RAB, member RAS oncogene

4 InterPro protein domains:
 IPR005225 Small_GTP-bd_dom
 IPR001806 Small_GTPase
 IPR003579 Small_GTPase_Rab_type
 IPR027417 P-loop_NTPase

Graphical View of Domain Structure for InterPro Entry O95716

ProtoNet protein and cluster: O95716

1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

UniProtKB/Swiss-Prot: RAB3D_HUMAN, O95716
Similarity: Belongs to the small GTPase superfamily. Rab family


RAB3D for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: RAB3D_HUMAN, O95716
Function: Protein transport. Probably involved in regulated exocytosis (By similarity)
Induction: Activated in myeloid differentiation

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003924GTPase activity TAS10023084
GO:0005515protein binding ----
GO:0005525GTP binding IEA--
GO:0051020GTPase binding IEA--
     
RAB3D for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for RAB3D:
 Upregulation of Wnt/beta-caten 

     7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rab3d):
 behavior/neurological  growth/size/body  homeostasis/metabolism  mortality/aging  nervous system 
 normal  respiratory system 

RAB3D for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Rab3dtm1Rja for RAB3D

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB3D
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB3D

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAB3D
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB3D

miRNA
Products:
    
miRTarBase miRNAs that target RAB3D:
hsa-mir-335-5p (MIRT018959), hsa-mir-375 (MIRT020003)

Block miRNA regulation of human, mouse, rat RAB3D using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate RAB3D (see all 32):
hsa-miR-345 hsa-miR-15a hsa-miR-578 hsa-miR-30d hsa-miR-30a hsa-miR-124 hsa-miR-424 hsa-miR-506
SwitchGear 3'UTR luciferase reporter plasmidRAB3D 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for RAB3D
Predesigned siRNA for gene silencing in human, mouse, rat RAB3D

Gene Editing
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OriGene clones in human, mouse for RAB3D (see all 8)
OriGene ORF clones in mouse, rat for RAB3D
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GenScript: all cDNA clones in your preferred vector: RAB3D (NM_004283)
Sino Biological Human cDNA Clone for RAB3D
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB3D
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB3D

Cell Line
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GenScript Custom overexpressing Cell Line Services for RAB3D
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB3D


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
RAB3D_HUMAN, O95716: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane5
cytosol3
mitochondrion2
cytoskeleton1
extracellular1
golgi apparatus1
nucleus1

Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005622intracellular ----
GO:0005634nucleus ----
GO:0005737cytoplasm ----
GO:0005739mitochondrion IEA--
GO:0005886plasma membrane IEA--

RAB3D for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for RAB3D About    
See pathways by source

SuperPathContained pathways About
1Sertoli-Sertoli Cell Junction Dynamics
Epithelial Tight Junctions0.36
2Pancreatic secretion
Pancreatic secretion

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB3D
    Epithelial Tight Junctions



1 Kegg Pathway  (Kegg details for RAB3D):
    Pancreatic secretion


RAB3D for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB3D
Interactions:

    GeneGlobe Interaction Network for RAB3D

STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

Selected Interacting proteins for RAB3D (O957163 ENSP000002221204) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
InteractantInteraction Details
GeneCardExternal ID(s)
RIMS2Q9UQ263, ENSP000003862284I2D: score=4 STRING: ENSP00000390665 STRING: ENSP00000386228
RPH3ALQ9UNE23, ENSP000003192104I2D: score=4 STRING: ENSP00000319210
RIMS1Q86UR53, ENSP000002648394I2D: score=3 STRING: ENSP00000264839
CCDC64BA1A5D93, ENSP000003739984STRING: ENSP00000373998 I2D: score=1 
CHMP243863, ENSP000003503864I2D: score=1 STRING: ENSP00000350386
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Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006184GTP catabolic process TAS10023084
GO:0006886intracellular protein transport ----
GO:0006887exocytosis IEA--
GO:0006913nucleocytoplasmic transport ----
GO:0007165signal transduction ----

RAB3D for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for RAB3D



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for RAB3D gene: 
NM_004283.3  

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000222120(uc002mqx.3) ENST00000589655
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat RAB3D using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate RAB3D (see all 32):
hsa-miR-345 hsa-miR-15a hsa-miR-578 hsa-miR-30d hsa-miR-30a hsa-miR-124 hsa-miR-424 hsa-miR-506
SwitchGear 3'UTR luciferase reporter plasmidRAB3D 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for RAB3D
Predesigned siRNA for gene silencing in human, mouse, rat RAB3D
Clone
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OriGene clones in human, mouse for RAB3D (see all 8)
OriGene ORF clones in mouse, rat for RAB3D
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: RAB3D (NM_004283)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB3D
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB3D
Primer
Products:
    
OriGene qPCR primer pairs and template standards for RAB3D
OriGene qSTAR qPCR primer pairs in human, mouse for RAB3D
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB3D
  QuantiTect SYBR Green Assays in human, mouse, rat RAB3D
  QuantiFast Probe-based Assays in human, mouse, rat RAB3D

Selected AceView cDNA sequences (see all 424):

AW002095 BQ233209 BQ182295 AW407316 AA402550 BG686934 BU732118 BU539806 
AI418957 BM792080 AI200178 BU734255 CK299243 W67281 BE673346 BU153815 
BX509018 BE645743 BM826449 AI246055 BM974589 BC016471 BM701416 AI279073 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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RAB3D expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACCACAGGGG
RAB3D Expression
About this image


RAB3D expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Cerebral Cortex
 
 Blood (Hematopoietic System)    fully expand to see all 2 entries
         Granulocytes Peripheral Blood
 
 Testis (Reproductive System)
         Leydig Cells Testis Interstitium
 
 Ovary (Reproductive System)
RAB3D Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

RAB3D Protein Expression

UniProtKB/Swiss-Prot: RAB3D_HUMAN, O95716
Tissue specificity: Highly expressed in granulocytes of peripheral blood. Constitutively expressed at low levels
in all hematopoietic cell lines investigated

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QuantiFast Probe-based Assays in human, mouse, rat RAB3D
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB3D

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for RAB3D gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Rab3d1 , 5 RAB3D, member RAS oncogene family1, 5 87.21(n)1
94.52(a)1
  9 (7.91 cM)5
193401  NM_031874.41  NP_114080.21 
 219074915 
lizard
(Anolis carolinensis)
Reptilia RAB3D6
RAB3D, member RAS oncogene family
80(a)
1 ↔ 1
2(79253936-79262790)
African clawed frog
(Xenopus laevis)
Amphibia BC043857.12   -- 79.08(n)    BC043857.1 
zebrafish
(Danio rerio)
Actinopterygii rab3da1 RAB3D, member RAS oncogene family, a 72.6(n)
79.91(a)
  567288  NM_001145597.1  NP_001139069.1 
fruit fly
(Drosophila melanogaster)
Insecta Rab33 neurotransmitter secretion RAB small
monomeric more
74(a)   47B7   --
worm
(Caenorhabditis elegans)
Secernentea rab-33 synaptic vesicle-associated GTP-binding
protein
73(a)   II(5722291-5724698)   --


ENSEMBL Gene Tree for RAB3D (if available)
TreeFam Gene Tree for RAB3D (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for RAB3D gene
RAB102  RAB3B2  RAB262  RAB8A2  RAB372  RAB3A2  RAB8B2  RAB1B2  
RAB122  RAB1A2  RAB132  RAB3C2  
Selected SIMAP similar genes for RAB3D using alignment to 1 protein entry:     RAB3D_HUMAN(see all similar genes):
RAB3A    RAB3B    RAB3C    RAB8B    RAB10    RAB35
RAB8A    RAB30    RAB27A    RAB11B    RAB1C    RAB13
RAB15    RAB11A    DKFZp686J07132    RAB27B    RAB39B    RAB23

RAB3D for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for RAB3D (see all 288)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 19 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs572863341,2
C--11433786(+) AAAAA-/ACAAAA 1 -- ut310--------
rs1929436121,2
--11438185(+) TTCTCC/GTGCTT 1 -- int10--------
rs1508345561,2
C--11438232(+) ACCATA/GCCAGG 1 -- int10--------
rs1845874811,2
--11438445(+) GGCAGC/GAGAAT 1 -- int10--------
rs1397481361,2
--11438593(+) AAACTA/GCAGAA 1 -- int10--------
rs1430338071,2
--11438839(+) ACCCCA/GTCTCT 1 -- int10--------
rs1890870961,2
--11438981(+) CTCCAA/GGCTGG 1 -- int10--------
rs1435533351,2
--11439030(+) AAAAA-/GAAGAA 1 -- int10--------
rs285941881,2
C--11439101(+) GGTGGA/GCGGAT 1 -- int10--------
rs1135274311,2
C,F--11439137(+) GGCCAG/ATACGG 1 -- int13Minor allele frequency- A:0.50WA CSA 6

HapMap Linkage Disequilibrium report for RAB3D (11432722 - 11456946 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for RAB3D:    About this table    
Variant IDTypeSubtypePubMed ID
nsv833752CNV Loss17160897
nsv519802CNV Loss19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing RAB3D
DNA2.0 Custom Variant and Variant Library Synthesis for RAB3D

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 604350    OMIM disorders: --

14 diseases for RAB3D:    
About MalaCards
tumor of exocrine pancreas    esophageal varix    varicose veins    sjogren's syndrome
glioblastoma multiforme    esophagitis    tonsillitis    alzheimer's disease
endotheliitis    cerebritis    pancreatitis    thyroiditis
neuronitis    prostatitis

1 disease from the University of Copenhagen DISEASES database for RAB3D:
Varicose veins

RAB3D for disorders           About GeneDecksing

Genetic Association Database (GAD): RAB3D
Human Genome Epidemiology (HuGE) Navigator: RAB3D (1 document)

Export disorders for RAB3D gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for RAB3D gene, integrated from 10 sources (see all 39):
(articles sorted by number of sources associating them with RAB3D)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Molecular cloning of cDNA encoding human Rab3D whose expression is upregulated with myeloid differentiation. (PubMed id 10023084)1, 2, 3, 9 Nishio H.... Yamaguchi Y. (Biochim. Biophys. Acta 1999)
  2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  4. Assignment of the GOV (Glioblastoma overexpressed) gene to human chromosome band 19p13.2 by fluorescence in situ hybridization. (PubMed id 10072586)1, 3 Chen X.N....Sehgal A. (Cytogenet. Cell Genet. 1998)
  5. Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells. (PubMed id 15257287)1, 9 Knop M....Gerke V. (EMBO J. 2004)
  6. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. (PubMed id 23505323)1 Weissglas-Volkov D....Pajukanta P. (J. Med. Genet. 2013)
  7. Rab3D is critical for secretory granule maturation in PC12 cells. (PubMed id 23526941)1 KAPgel T....Gerdes H.H. (PLoS ONE 2013)
  8. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  9. Changes in Rab3D expression and distribution in the acini of SjAPgren's syndrome patients are associated with loss of cell polarity and secretory dysfunction. (PubMed id 21702009)1 Bahamondes V....GonzA!lez M.J. (Arthritis Rheum. 2011)
  10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 9545 HGNC: 9779 AceView: RAB3DandUNQ501 Ensembl:ENSG00000105514 euGenes: HUgn9545
ECgene: RAB3D Kegg: 9545 H-InvDB: RAB3D

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for RAB3D Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for RAB3D Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for RAB3D gene:
Search GeneIP for patents involving RAB3D

GeneCards and IP:
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