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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB3A Gene

protein-coding   GIFtS: 65
GCID: GC19M018307

RAB3A, member RAS oncogene family

 Explore 11 diseases affiliated with
RAB3A via our new
 Human Malady Compendium 
Biological research products
for RAB3A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
RAB3A, Member RAS Oncogene Family1 2
RAS-Associated Protein RAB3A2
Ras-Related Protein Rab-3A2

External Ids:    HGNC: 97771   Entrez Gene: 58642   Ensembl: ENSG000001056497   OMIM: 1794905   UniProtKB: P203363   

Export aliases for RAB3A gene to outside databases

Previous GC identifers: GC19M018801 GC19M018699 GC19M018152 GC19M018168 GC19M017871


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RAB3A_HUMAN, P20336
Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in
neurotransmitter release by regulating membrane flow in the nerve terminal

Gene Wiki entry for RAB3A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB3A gene promoter:
         MEF-2A   ISGF-3   GCNF   GCNF-1   HOXA5   Pax-2   Pax-2a   GCNF-2   LCR-F1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB3A promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB3A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.2

RAB3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB3A gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M018307:  view genomic region     (about GC identifiers)

Start:
18,307,594 bp from pter      End:
18,314,874 bp from pter
Size:
7,281 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RAB3A_HUMAN, P20336 (See protein sequence)
Recommended Name: Ras-related protein Rab-3A  
Size: 220 amino acids; 24984 Da
Subunit: Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL.
Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1
and SGSM3 (By similarity)
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Secondary accessions: A8K0J4 Q9NYE1

Explore the universe of human proteins at neXtProt for RAB3A: NX_P20336

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P20336

  • RAB3A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002857.1  
    ENSEMBL proteins: 
     ENSP00000222256  
    Reactome Protein details: P20336
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    Uscn Proteins for RAB3A

    Gene Ontology (GO): 5/14 cellular component terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001669acrosomal vesicle IEA--
    GO:0005625soluble fraction ----
    GO:0005626insoluble fraction ----
    GO:0005737cytoplasm ----
    GO:0005829cytosol IEA--


    RAB3A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RAB3A for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type

    Graphical View of Domain Structure for InterPro Entry P20336

    ProtoNet protein and cluster: P20336

    1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB3A_HUMAN, P20336
    Similarity: Belongs to the small GTPase superfamily. Rab family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RAB3A_HUMAN, P20336
    Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in
    neurotransmitter release by regulating membrane flow in the nerve terminal

         Genatlas biochemistry entry for RAB3A:
    RAB3A,Ras oncogene superfamily member,expressed synaptic vesicles, involved in calcium regulated exocytosis,expressed
    in parathyroid chief cells

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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001671ATPase activator activity IEA--
    GO:0003924GTPase activity IMP10859313
    GO:0005515protein binding IPI10859313
    GO:0005525GTP binding IEA--
    GO:0008022protein C-terminus binding IEA--


    RAB3A for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for RAB3A:
     Decreased CXCL12 induced migra  Decreased nuclei size in G2M  Increased circadian period len 

    Animal Models:
         Mouse knock-out Rab3atm1Sud for RAB3A
         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Rab3a):
     behavior/neurological  growth/size  homeostasis/metabolism  mortality/aging  nervous system 
     normal  respiratory system 

    RAB3A for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Serotonin Neurotransmitter Release Cycle
    Serotonin Neurotransmitter Release Cycle1.00
    Acetylcholine Neurotransmitter Release Cycle0.53
    Dopamine Neurotransmitter Release Cycle1.00
    Glutamate Neurotransmitter Release Cycle0.42
    Norepinephrine Neurotransmitter Release Cycle0.60
    2GABA synthesis, release, reuptake and degradation
    GABA synthesis, release, reuptake and degradation1.00
    Neurotransmitter Release Cycle0.53
    3Transmission across Chemical Synapses
    Transmission across Chemical Synapses1.00
    Neuronal System0.67
    4Cytoskeletal Signaling
    Cytoskeletal Signaling1.00
    5Synaptic Vesicle Pathway
    Synaptic Vesicle Pathway1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for RAB3A
        Epithelial Tight Junctions

    1 Cell Signaling Technology (CST) Pathway for RAB3A
        Cytoskeletal Signaling

    1 BioSystems Pathway for RAB3A 
        Synaptic Vesicle Pathway

    5/9        Reactome Pathways for RAB3A (see all 9)
        Acetylcholine Neurotransmitter Release Cycle
    Transmission across Chemical Synapses
    GABA synthesis, release, reuptake and degradation
    Neurotransmitter Release Cycle
    Neuronal System



    RAB3A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAB3A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/41 Interacting proteins for RAB3A (P203362, 3 ENSP000002222564) via UniProtKB, MINT, STRING, and/or I2D (see all 41)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RIMS2Q9UQ263, ENSP000003862284I2D: score=5 STRING: ENSP00000390665 STRING: ENSP00000386228
    RPH3ALQ9UNE23, ENSP000003192104I2D: score=5 STRING: ENSP00000319210
    SYTL4Q96C243, ENSP000002630334I2D: score=3 STRING: ENSP00000263033
    CHMP243863, ENSP000003503864I2D: score=2 STRING: ENSP00000350386
    CHMLP263743, ENSP000003555114I2D: score=2 STRING: ENSP00000355511
    About this table

    Gene Ontology (GO): 5/20 biological process terms (GO ID links to tree view) (see all 20):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003016respiratory system process IEA--
    GO:0006184GTP catabolic process TAS2501306
    GO:0007005mitochondrion organization IEA--
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0007268synaptic transmission TAS--


    RAB3A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RAB3A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RAB3A
    5 Novoseek chemical compound relationships for RAB3A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gtp 68.7 20 8886977 (3), 7926025 (3), 8387493 (2), 9252412 (1) (see all 9)
    gdp 65.2 8 19546222 (2), 9252412 (1), 7926025 (1), 8188702 (1) (see all 5)
    sucrose 5 1 8886977 (1)
    calcium 3.73 10 11522668 (3), 10954749 (2), 17625073 (2), 19546222 (1)
    norepinephrine 0 4 8636125 (2)

    Search CenterWatch for drugs/clinical trials and news about RAB3A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB3A gene: 
    NM_002866.4  

    Unigene Cluster for RAB3A:

    RAB3A, member RAS oncogene family
    Hs.27744  [show with all ESTs]
    Unigene Representative Sequence: NM_002866
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000222256(uc002nie.2) ENST00000464076 ENST00000481914

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    Additional cDNA sequence: 

    AF254795.1 AF498931.1 AK289559.1 AK293467.1 BC011782.2 M28210.1 

    6 DOTS entries:

    DT.444206  DT.100653326  DT.100668937  DT.40110695  DT.95301547  DT.95171615 

    24/124 AceView cDNA sequences (see all 124):

    AL534649 AW205866 BX419052 BI917111 AW205498 BM673547 AW163583 BM926739 
    AA364643 BX442130 BU739142 AW160374 BC011782 BQ898770 CA309409 BP360364 
    CD615936 NM_002866 BM926805 AA339014 BU856756 BX375602 BI820799 BG911099 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RAB3A    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b
    SP1:                    -           -                           
    SP2:                    -     -     -                           
    SP3:                                -                           
    SP4:                    -                                       


    ECgene alternative splicing isoforms for RAB3A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACAACACTAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RAB3A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB3A

    SOURCE GeneReport for Unigene cluster: Hs.27744

    UniProtKB/Swiss-Prot: RAB3A_HUMAN, P20336
    Tissue specificity: Specifically expressed in brain

        SABiosciences Expression via Pathway-Focused PCR Array including RAB3A: 
              Synaptic Plasticity in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RAB3A gene from 6/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.213462 Xenopus laevis transcribed sequence with strong similarity more 80.97(n)    BX848352.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab3ab1 RAB3A, member RAS oncogene family, b 80.61(n)
    94.09(a)
      550457  NM_001017761.1  NP_001017761.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab33 neurotransmitter secretion RAB small
    monomeric more
    76(a)   47B7   --
    worm
    (Caenorhabditis elegans)
    Secernentea rab-33 synaptic vesicle-associated GTP-binding
    protein
    76(a)   II(5722291-5724698)   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RAB8A6
    AT5G598406
    (see all 5)
    Ras-related protein Rab-8A
    (see all 5)
    45(a)
    45(a)
    (see all 5)
    possible ortholog
    possible ortholog
    (see all 5)
    3(16917589-16920018)
    5(24107215-24109251)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 4)
    ras-related protein, putative, expressed
    (see all 4)
    46(a)
    46(a)
    (see all 4)
    possible ortholog
    possible ortholog
    (see all 4)
    7(7741968-7745786)
    7(5144086-5147755)


    ENSEMBL Gene Tree for RAB3A (if available)
    TreeFam Gene Tree for RAB3A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB3A gene
    RAB232  RAB27A2  RAB3B2  RAB27B2  RAB3D2  RAB3C2  
    18/86 SIMAP similar genes for RAB3A using alignment to 2 protein entries:     RAB3A_HUMAN (see all proteins) (see all similar genes):
    RAB3C    RAB3B    RAB3D    RAB8B    RAB13    RAB8A
    RAB15    RAB10    RAB30    RAB35    RAB1C    RAB27A
    RAB27B    RAB26    RAB41    RAB11A    DKFZp686J07132    RAB11B

    RAB3A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/145 NCBI SNPs in RAB3A are shown (see all 145    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs115521601,2
    F,--18307224(-) GGAGCT/GCTGGA 2 -- int1 ut311Minor allele frequency- G:0.12NA 120
    rs115521581,2
    C,--18307257(-) AGTCAT/CGTCCC 2 -- int1 ut312Minor allele frequency- C:0.10CSA WA 120
    rs1490807411,2
    --18307259(+) GACATA/GACTGA 2 -- ut31 int10--------
    rs1896165361,2
    --18307303(+) CCCCAA/GAAGTT 2 -- ut31 int10--------
    rs1459204981,2
    --18307444(+) TTCCCA/GAGGCT 2 -- int1 ut310--------
    rs11280991,2
    C,F,--18307468(+) TGCTCG/AAGGCC 2 -- ut31 int19Minor allele frequency- A:0.27MN WA NA CSA 434
    rs115521591,2
    F,--18307471(-) CCTGGC/ACTCGA 2 -- ut31 int12Minor allele frequency- A:0.07WA NA 238
    rs1157724331,2
    F,--18307637(+) GGTGCG/ATGTAG 2 -- ds5001 ut311Minor allele frequency- A:0.03WA 118
    rs739254381,2
    C,--18307717(+) GGGCGA/GGGGGG 2 -- ds5001 ut311Minor allele frequency- G:0.00WA 2
    rs1483400021,2
    C,--18307756(+) GCACA-/CCCCCC 2 -- ut31 ds50010--------

    HapMap Linkage Disequilibrium report for RAB3A (18307594 - 18314874 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for RAB3A
         2 CNVs: 5093 58863

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RAB3A for disorders           About GeneDecksing

    OMIM gene information: 179490    OMIM disorders: --

    11 diseases for RAB3A:    About MalaCards
    ebd    multiple system atrophy    choroideremia    alzheimer's disease
    huntington's disease    insulinoma    choroiditis    cholesterol
    neuroblastoma    pancreatitis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for RAB3A:
    Choroideremia

    2 Novoseek disease relationships for RAB3A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    alzheimers disease 12.3 1 11351135 (1)
    tumors 0 4 11074007 (1), 1384950 (1), 19212825 (1)

    Human Genome Epidemiology (HuGE) Navigator: RAB3A (1 document)
    Tumor Gene Database (TGDB): RAB3A

    Export disorders for RAB3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB3A gene, integrated from 9 sources (see all 101):
    (articles sorted by number of sources associating them with RAB3A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A. (PubMed id 7991565)1, 2, 9 Farnsworth C.C.... Glomset J.A. (1994)
    2. Isoprenoid modification of rab proteins terminating in CC or CXC motifs. (PubMed id 1648736)1, 2, 9 Khosravi-Far R.... Der C.J. (1991)
    3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND. (PubMed id 10574328)1, 2 Sullivan M.... Houslay M.D. (1999)
    6. Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A. (PubMed id 7532276)1, 3 Brondyk W.H....Macara I.G. (1995)
    7. The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion. (PubMed id 2501306)1, 2 Zahraoui A.... Tavitian A. (1989)
    8. Chromosome mapping of the human ras-related rab3A gene to 19p13.2. (PubMed id 2687157)1, 3 Rousseau-Merck M.F....Berger R. (1989)
    9. Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease. (PubMed id 15207266)1, 9 Dalfo E....Ferrer I. (2004)
    10. Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A. (PubMed id 10025402)1, 9 Ostermeier C. and Brunger A.T. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5864 HGNC: 9777 AceView: RAB3A Ensembl:ENSG00000105649 euGenes: HUgn5864
    ECgene: RAB3A H-InvDB: RAB3A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB3A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB3A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB3A gene:
    Search GeneIP for patents involving RAB3A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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