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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB38 Gene

protein-coding   GIFtS: 59
GCID: GC11M087846

RAB38, Member RAS Oncogene Family

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RAB38, Member RAS Oncogene Family1 2
Melanoma Antigen NY-MEL-12 3
NY-MEL-12
Rab-Related GTP-Binding Protein2
Ras-Related Protein Rab-382
rrGTPbp2

External Ids:    HGNC: 97761   Entrez Gene: 236822   Ensembl: ENSG000001238927   OMIM: 6062815   UniProtKB: P577293   

Export aliases for RAB38 gene to outside databases

Previous GC identifers: GC11M090169 GC11M089393 GC11M088030 GC11M087534 GC11M087486 GC11M084086


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RAB38 Gene: 
RAB38 (RAB38, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB38 include platelet storage pool deficiency, and oculocutaneous albinism. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RABL2B.

UniProtKB/Swiss-Prot: RAB38_HUMAN, P57729
Function: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Plays a
role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis

Gene Wiki entry for RAB38 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB38 gene promoter:
         STAT5A   HNF-3beta   PPAR-gamma1   POU2F1   POU2F1a   POU2F1b   STAT3   PPAR-gamma2   POU2F1c   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB38 promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB38

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB38


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q14   Ensembl cytogenetic band:  11q14.2   HGNC cytogenetic band: 11q14

RAB38 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB38 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M087846:  view genomic region     (about GC identifiers)

Start:
87,846,410 bp from pter      End:
87,908,635 bp from pter
Size:
62,226 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RAB38_HUMAN, P57729 (See protein sequence)
Recommended Name: Ras-related protein Rab-38  
Size: 211 amino acids; 23712 Da
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Melanosome. Cytoplasmic vesicle,
phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity).
Note=Recruited to phagosomes containing S.aureus or M.tuberculosis
Secondary accessions: Q53XK7

Explore the universe of human proteins at neXtProt for RAB38: NX_P57729

Explore proteomics data for RAB38 at MOPED 

Post-translational modifications:

  • UniProtKB: Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system
    that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not
    methylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P57729

  • RAB38 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RAB38 Protein Expression
    REFSEQ proteins: NP_071732.1  
    ENSEMBL proteins: 
     ENSP00000243662   ENSP00000435340   ENSP00000433317  

    Human Recombinant Protein Products for RAB38: 
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    Novus Biologicals RAB38 Proteins
    Novus Biologicals RAB38 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RAB38 

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005886plasma membrane IEA--

    RAB38 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry P57729

    ProtoNet protein and cluster: P57729

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB38_HUMAN, P57729
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RAB38 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB38_HUMAN, P57729
    Function: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Plays a
    role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity NAS10910072
    GO:0005515protein binding ----
    GO:0005525GTP binding NAS10910072
         
    RAB38 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB38:
     Upregulation of Wnt/beta-caten 

         7 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Rab38):
     hematopoietic system  homeostasis/metabolism  integument  no phenotypic analysis  pigmentation 
     respiratory system  vision/eye 

    RAB38 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RAB38 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RAB38

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAB38 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB38 

    miRNA
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    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB38 (see all 12):
    hsa-miR-30c hsa-miR-4307 hsa-miR-200a hsa-miR-30d hsa-miR-33a* hsa-miR-141 hsa-miR-4261 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidRAB38 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RAB38
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of RAB38

    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of RAB38 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB38


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RAB38 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cytoskeletal Signaling
    Cytoskeletal Signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for RAB38
        Cytoskeletal Signaling




    RAB38 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAB38

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/7 Interacting proteins for RAB38 (P577293 ENSP000002436624) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD2Q157963, ENSP000002621604I2D: score=3 STRING: ENSP00000262160
    SMAD3P840223, ENSP000003329734I2D: score=3 STRING: ENSP00000332973
    SMAD1Q157973, ENSP000003057694I2D: score=3 STRING: ENSP00000305769
    BMPR1BO002383, ENSP000002645684I2D: score=3 STRING: ENSP00000264568
    SMAD4Q134853, ENSP000003415514I2D: score=3 STRING: ENSP00000341551
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process NAS10910072
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction NAS10910072

    RAB38 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RAB38

    Search CenterWatch for drugs/clinical trials and news about RAB38

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB38 gene: 
    NM_022337.2  

    Unigene Cluster for RAB38:

    RAB38, member RAS oncogene family
    Hs.591975  [show with all ESTs]
    Unigene Representative Sequence: NM_022337
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000243662(uc001pcj.2) ENST00000531138 ENST00000526372
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RAB38
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB38 (see all 12):
    hsa-miR-30c hsa-miR-4307 hsa-miR-200a hsa-miR-30d hsa-miR-33a* hsa-miR-141 hsa-miR-4261 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidRAB38 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for RAB38
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAB38
    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB38
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB38
    Sirion Biotech Customized lentivirus for stable overexpression of RAB38 
                         Customized lentivirus expression plasmids for stable overexpression of RAB38 
    Primer
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    OriGene qPCR primer pairs and template standards for RAB38
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAB38
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAB38

    Additional mRNA sequence: 

    AF136172.1 AF235022.1 BC015808.1 BT009842.1 

    3 DOTS entries:

    DT.70103105  DT.91670331  DT.95372185 

    24/65 AceView cDNA sequences (see all 65):

    BG260462 N42447 AL546159 AA164284 AI017581 CA443207 W94393 CR615812 
    CA443345 AW276528 BI857156 BM800816 AW518279 BE302086 BC015808 NM_022337 
    AI334984 N20169 BE736962 BQ231819 CD365214 CD105942 BE274396 BM995953 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RAB38    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
    SP1:                          -                                 
    SP2:                    -     -                                 
    SP3:                                                            
    SP4:                          -     -                           


    ECgene alternative splicing isoforms for RAB38

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB38 expression in normal human tissues (normalized intensities)      RAB38 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATATATAT
    RAB38 Expression
    About this image


    RAB38 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/10 selected tissues (see all 10) fully expand
     
     Epidermis (Integumentary System)    fully expand to see all 4 entries
             Human EpiDermal Melanocytes-medium (HEM-m)   
     
     Melanocytes (Integumentary System)    fully expand to see all 3 entries
             Human EpiDermal Melanocytes-medium (HEM-m)   
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Nose (Sensory Organs)
             sensory organ/nose/naso-lacrimal duct   

    See RAB38 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB38

    SOURCE GeneReport for Unigene cluster: Hs.591975

    UniProtKB/Swiss-Prot: RAB38_HUMAN, P57729
    Tissue specificity: Expressed in melanocytes

        SABiosciences Custom PCR Arrays for RAB38
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB38

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RAB38 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab381 , 5 RAB38, member of RAS oncogene family1, 5 90.68(n)1
    97.16(a)1
      7 (49.19 cM)5
    724331  NM_028238.71  NP_082514.41 
     884302735 
    chicken
    (Gallus gallus)
    Aves RAB381 RAB38, member RAS oncogene family 79.29(n)
    86.41(a)
      428095  XM_425653.2  XP_425653.2 
    lizard
    (Anolis carolinensis)
    Reptilia RAB386
    Uncharacterized protein
    80(a)
    1 ↔ 1
    3(199556946-199573568)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC053811.12   -- 77.48(n)    BC053811.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab38a1 RAB38a, member RAS oncogene family 74.13(n)
    78.57(a)
      100003274  XM_001342839.2  XP_001342875.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab-RP13 GTP binding 72(a)     --


    ENSEMBL Gene Tree for RAB38 (if available)
    TreeFam Gene Tree for RAB38 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB38 gene
    RABL2B2  RAB9A2  RAB7A2  RAB9B2  RAB322  RAB7L12  RABL2A2  
    18/61 SIMAP similar genes for RAB38 using alignment to 3 protein entries:     RAB38_HUMAN (see all proteins) (see all similar genes):
    RAB32    RAB6A'    RAB7L1    RAB11A    RAB7A    RAB34
    RANP1    RAB3A    RAB8B    RAB6A    RAB19    RAB11B
    RAB13    RAB25    RAB28    RAB6B    RAB43    RAB18

    RAB38 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for RAB38
    PGOHUM00000237033 PGOHUM00000237035


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1318 SNPs in RAB38 are shown (see all 1318)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0364154
    A colorectal cancer sample4--see VAR_0364152 K T mis40--------
    rs577036991,2
    --87845935(+) GACTCC/TGTCTC 1 -- int10--------
    rs606555571,2
    C--87845958(+) AACAA-/C/CAAA
            
    ATATA
    1 -- int10--------
    rs1929907111,2
    C--87845975(+) CATATA/C/G/
            
    TATAT
    1 -- int10--------
    rs1851064441,2
    --87846111(+) TATTGC/TTTCTT 1 -- int10--------
    rs1484797551,2
    --87846127(+) GTTGAC/TTGATC 1 -- int10--------
    rs1903473051,2
    --87846131(+) ATTGAC/TCTGGC 1 -- int10--------
    rs1819799821,2
    --87846205(+) CTGTAC/TACTCT 1 -- int10--------
    rs595005101,2
    C,F--87846311(+) ATCTCC/TTCCTT 1 -- int12Minor allele frequency- T:0.08NA EA 240
    rs3707008551,2
    C--87846365(+) TGTCC-/AAAAAAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for RAB38 (87846410 - 87908635 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RAB38:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2664391CNV Deletion23128226
    esv8555CNV Loss19470904
    nsv527214CNV Loss19592680
    nsv898081CNV Gain21882294
    esv275284CNV Gain+Loss21479260

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606281    OMIM disorders: --

    6 diseases for RAB38:    About MalaCards
    platelet storage pool deficiency    oculocutaneous albinism    albinism    melanoma
    hermansky-pudlak syndrome    tuberculosis

    2 diseases from the University of Copenhagen DISEASES database for RAB38:
    Hermansky-Pudlak syndrome     Oculocutaneous albinism

    RAB38 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for RAB38 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    albinism oculocutaneous 92.7 1 18413250 (1)

    Genetic Association Database (GAD): RAB38
    Human Genome Epidemiology (HuGE) Navigator: RAB38 (1 document)

    Export disorders for RAB38 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB38 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with RAB38)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Serological cloning of a melanocyte rab guanosine 5'-triphosphate- binding protein and a chromosome condensation protein from a melanoma complementary DNA library. (PubMed id 10910072)1, 2, 3, 9 Jaeger D.... Chen Y.-T. (2000)
    2. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)1, 4 Baranzini S.E....Oksenberg J.R. (2008)
    3. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)1, 2 Chi A....Hunt D.F. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. (PubMed id 12643545)1, 2 Basrur V.... Appella E. (2003)
    6. Characterization of the human RAB38 and RAB7 genes: exclusion of new major pathological loci for Japanese OCA. (PubMed id 12850305)1, 9 Suzuki T....Tomita Y. (2003)
    7. BLOC-2, AP-3, and AP-1 proteins function in concert wi th Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related o rganelles. (PubMed id 22511774)1 Bultema J.J....Di Pietro S.M. (2012)
    8. BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32 /38 guanine nucleotide exchange factor. (PubMed id 23084991)1 Gerondopoulos A....Barr F.A. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (PubMed id 21255211)2 Seto S.... Koide Y. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23682 HGNC: 9776 AceView: RAB38 Ensembl:ENSG00000123892 euGenes: HUgn23682
    ECgene: RAB38 H-InvDB: RAB38

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB38 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB38 Genetics and Cytogenetics in Oncology and Haematology
    SeattleSNPshttp://pga.gs.washington.edu/data/rab38/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB38 gene:
    Search GeneIP for patents involving RAB38

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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