Aliases for RAB38 Gene
External Ids for RAB38 Gene
Previous GeneCards Identifiers for RAB38 Gene
GeneCards Summary for RAB38 Gene
RAB38 (RAB38, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB38 include Frontotemporal Dementia and Hermansky-Pudlak Syndrome 5. Among its related pathways are Metabolism of proteins and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include GTP binding and protein complex binding. An important paralog of this gene is RAB32.
UniProtKB/Swiss-Prot for RAB38 Gene
May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).