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RAB37 Gene

protein-coding   GIFtS: 53
GCID: GC17P072666

RAB37, Member RAS Oncogene Family

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB37, Member RAS Oncogene Family1 2
RAB37, Member Of RAS Oncogene Family2
Ras-Related Protein Rab-372

External Ids:    HGNC: 302681   Entrez Gene: 3266242   Ensembl: ENSG000001727947   OMIM: 6099565   UniProtKB: Q96AX23   

Export aliases for RAB37 gene to outside databases

Previous GC identifers: GC17P073131 GC17P073264 GC17P073263 GC17P070178 GC17P068076


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB37 Gene:
Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional
background information on Rab proteins, see MIM 179508.(supplied by OMIM, Apr 2006)

GeneCards Summary for RAB37 Gene:
RAB37 (RAB37, member RAS oncogene family) is a protein-coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAB10.

Gene Wiki entry for RAB37 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB37 gene promoter:
         STAT5B   GATA-3   CBF-C   HNF-4alpha1   CBF-B   CBF-A   CP1A   NF-Y   NF-kappaB1   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): RAB37 promoter sequence
   Search Chromatin IP Primers for RAB37

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1   Ensembl cytogenetic band:  17q25.1   HGNC cytogenetic band: 17q25.2

RAB37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB37 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P072666:  view genomic region     (about GC identifiers)

Start:
72,666,717 bp from pter      End:
72,743,474 bp from pter
Size:
76,758 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RAB37_HUMAN, Q96AX2 (See protein sequence)
Recommended Name: Ras-related protein Rab-37 precursor  
Size: 223 amino acids; 24815 Da
Subunit: Interacts with RIMS1 (By similarity)
Secondary accessions: A8MXF5 A8MYT0 Q8IWA7
Alternative splicing: 4 isoforms:  Q96AX2-1   Q96AX2-2   Q96AX2-3   Q96AX2-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAB37: NX_Q96AX2

Explore proteomics data for RAB37 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys80, Lys115, Lys189

  • See RAB37 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001006639.1  NP_001157461.1  NP_001157462.1  NP_783865.1  

    ENSEMBL proteins: 
     ENSP00000341354   ENSP00000383934   ENSP00000432086   ENSP00000376391   ENSP00000376390  
     ENSP00000376389   ENSP00000376388   ENSP00000376387   ENSP00000436563  

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    Cloud-Clone Corp. Proteins for RAB37

     
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    antibodies-online proteins for RAB37 (4 products) 

     
    antibodies-online peptides for RAB37

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    antibodies-online antibodies for RAB37 (33 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q96AX2

    ProtoNet protein and cluster: Q96AX2

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB37_HUMAN, Q96AX2
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB37           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005515protein binding ----
    GO:0005525GTP binding IEA--
         
    Find genes that share ontologies with RAB37           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB37:
     Increased cilium length after  

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RAB37

    miRNA
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    miRTarBase miRNAs that target RAB37:
    hsa-mir-335-5p (MIRT017801)

    Block miRNA regulation of human, mouse, rat RAB37 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB37 (see all 14):
    hsa-miR-217 hsa-miR-429 hsa-miR-198 hsa-miR-488 hsa-miR-519c-3p hsa-miR-520a-5p hsa-miR-519a hsa-miR-519b-3p
    SwitchGear 3'UTR luciferase reporter plasmidRAB37 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB37

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB37


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB37_HUMAN, Q96AX2: Cytoplasmic vesicle. Note=Secretory granules (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    plasma membrane1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005793endoplasmic reticulum-Golgi intermediate compartment IDA15308636
    GO:0016020membrane ----

    Find genes that share ontologies with RAB37           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB37
    Interactions:

        GeneGlobe Interaction Network for RAB37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for RAB37 (Q96AX23 ENSP000003763894) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB5AP203393, ENSP000002730474I2D: score=1 STRING: ENSP00000273047
    RIMS1Q86UR53, ENSP000002648394I2D: score=3 STRING: ENSP00000264839
    EWSR1Q018443, ENSP000003810314I2D: score=2 STRING: ENSP00000381031
    DTX4Q9Y2E63I2D: score=5 
    PCSK5Q928243I2D: score=5 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    Find genes that share ontologies with RAB37           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB37



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB37 gene (5 alternative transcripts): 
    NM_001006637.1  NM_001006638.2  NM_001163989.1  NM_001163990.1  NM_175738.4  

    Unigene Cluster for RAB37:

    RAB37, member RAS oncogene family
    Hs.351413  [show with all ESTs]
    Unigene Representative Sequence: NM_175738
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340415(uc002jld.2 uc010dfu.3) ENST00000402449 ENST00000392617(uc002jlc.2)
    ENST00000528438 ENST00000392615 ENST00000392614(uc010wrb.2 uc010wrc.2)
    ENST00000392613 ENST00000533530 ENST00000527040 ENST00000577548 ENST00000392612(uc010wre.2)
    ENST00000392610(uc002jlk.3) ENST00000481224 ENST00000488977 ENST00000531420

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    Selected qRT-PCR Assays for microRNAs that regulate RAB37 (see all 14):
    hsa-miR-217 hsa-miR-429 hsa-miR-198 hsa-miR-488 hsa-miR-519c-3p hsa-miR-520a-5p hsa-miR-519a hsa-miR-519b-3p
    SwitchGear 3'UTR luciferase reporter plasmidRAB37 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RAB37
    Predesigned siRNA for gene silencing in human, mouse, rat RAB37
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    GenScript: all cDNA clones in your preferred vector (see all 4): RAB37 (NM_001006638)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB37
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB37
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    OriGene qSTAR qPCR primer pairs in human, mouse for RAB37
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB37
      QuantiTect SYBR Green Assays in human, mouse, rat RAB37
      QuantiFast Probe-based Assays in human, mouse, rat RAB37

    Additional mRNA sequence: 

    AK057069.1 AK098068.1 AK290202.1 AK296062.1 AK296172.1 AK298033.1 AK303442.1 BC040547.1 

    14 DOTS entries:

    DT.101979436  DT.40123007  DT.100698980  DT.92047341  DT.120912026  DT.100819714  DT.100819720  DT.95372825 
    DT.70100539  DT.100804565  DT.120912024  DT.120912205  DT.40116956  DT.120912031 

    Selected AceView cDNA sequences (see all 67):

    BQ188402 AK054846 BG283602 BC016615 BM706070 CK299601 CR601310 AK057069 
    BQ183276 BM921365 AI864721 AK098068 AL522282 BQ028124 BX351009 BX342475 
    BX328183 BM981939 AA310682 BX342476 BI819064 BX391966 AK127073 BC040547 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RAB37 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b · 12c · 12d · 12e ^ 13
    SP1:                                                                                -     -     -                 -                 -     -     -         
    SP2:                          -     -     -     -     -                             -     -     -                 -                                       
    SP3:                                                                                -     -     -                 -                                       
    SP4:                          -     -     -     -     -                             -     -     -                                                         
    SP5:                                                  -                             -     -     -                 -                                       


    ECgene alternative splicing isoforms for RAB37

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB37 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCTGCAGGC
    RAB37 Expression
    About this image


    RAB37 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 8 entries
             Mature Endothelial Cells Blood Brain Barrier
             Cerebral Cortex
             Olfactory Bulb   
     
     Endothelium (Cardiovascular System)
             Mature Endothelial Cells Blood Brain Barrier
    RAB37 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB37 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.351413
        Custom PCR Arrays for RAB37
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB37

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB37 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab371 , 5 RAB37, member of RAS oncogene family1, 5 88.94(n)1
    93.72(a)1
      11 (80.59 cM)5
    582221  NM_021411.41  NP_067386.31 
     1150914315 
    chicken
    (Gallus gallus)
    Aves RAB376
    RAB37, member RAS oncogene family
    64(a)
    1 ↔ 1
    18(10703909-10709349)
    lizard
    (Anolis carolinensis)
    Reptilia RAB376
    RAB37, member RAS oncogene family
    69(a)
    1 ↔ 1
    2(115860490-115967122)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.141102 Transcribed sequence with weak similarity to protein more 75.21(n)    BX719848.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1121831 zgc:112183 72.22(n)
    75.98(a)
      550410  NM_001017715.1  NP_001017715.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab266
    Rab26
    31(a)
    1 → many
    3L(21311874-21327290)
    worm
    (Caenorhabditis elegans)
    Secernentea rab-371 rab-37 57.8(n)
    57.45(a)
      180696  NM_001047829.1  NP_001041294.1 


    ENSEMBL Gene Tree for RAB37 (if available)
    TreeFam Gene Tree for RAB37 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB37 gene
    RAB102  RAB3B2  RAB262  RAB8A2  RAB3D2  RAB3A2  RAB8B2  RAB1B2  
    RAB122  RAB1A2  RAB132  RAB3C2  
    Selected SIMAP similar genes for RAB37 using alignment to 7 protein entries:     RAB37_HUMAN (see all proteins) (see all similar genes):
    RAB26    rab1b    RAB8B    RAB10    RAB2A    DKFZp313C1541
    RAB42    RAB8A    RAB39B    RAB15    RAB14    RAB11A
    RAB13    RAB19    RAB3A    RAB2B    RAB3C    RAB1C

    Find genes that share paralogs with RAB37           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for RAB37
    PGOHUM00000261134


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB37 (see all 1120)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1467265341,2
    C--72665481(+) ATCTCC/TAGATT 1 -- us2k10--------
    rs1488655231,2
    --72665484(+) TCTAGA/GTTGGT 1 -- us2k10--------
    rs1827512471,2
    --72665695(+) TTCTGA/GATTGG 1 -- us2k10--------
    rs1155336161,2
    F--72665720(+) TATTTG/ACTCTA 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1436238211,2
    --72665811(+) GTGAGA/GTTCCA 1 -- us2k10--------
    rs568159871,2
    F--72665874(+) CTCAGA/GAGAAA 1 -- us2k10--------
    rs1897944661,2
    --72665891(+) ATGAGC/TGAGTC 1 -- us2k10--------
    rs1823748011,2
    --72665926(+) TTGAGC/TATAGA 1 -- us2k10--------
    rs1159843841,2
    C,F--72665933(+) TAGACA/GACTTT 1 -- us2k11Minor allele frequency- G:0.05WA 118
    rs1870457161,2
    --72665939(+) ACTTTA/GAGAAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RAB37 (72666717 - 72743474 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for RAB37:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv4044CNV Deletion18987735
    esv2716232CNV Deletion23290073
    esv2574609CNV Insertion19546169
    nsv2140CNV Loss18451855
    esv8799CNV Loss19470904
    esv33995CNV Loss17666407
    nsv908743CNV Loss21882294
    esv2751770CNV Gain17911159
    dgv372n27CNV Gain19166990
    nsv517569CNV Gain+Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609956    OMIM disorders: --


    Find genes that share disorders with RAB37           About GenesLikeMe

    Genetic Association Database (GAD): RAB37

    Export disorders for RAB37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB37 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with RAB37)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. (PubMed id 20031577)1, 4 Danik J.S....Ridker P.M. (Circ Cardiovasc Genet 2009)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (Nat. Biotechnol. 2003)
    5. Rab37 is a novel mast cell specific GTPase localized to secretory granules. (PubMed id 10722846)1, 3 Masuda E.S....Scheller R.H. (FEBS Lett. 2000)
    6. Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells. (PubMed id 19148500)1, 9 Dobashi S....Nakamura Y. (Oncol. Rep. 2009)
    7. An association study on genetic polymorphisms of Rab37 gene with the risk of esophageal squamous cell carcinoma in a Chinese Han population. (PubMed id 23372429)1 Xu X....Bai Y. (Int J Med Sci 2013)
    8. Multiethnic meta-analysis of genome-wide association studies in &gt;100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. (PubMed id 23969696)1 Sabater-Lleal M....O'Donnell C.J. (Circulation 2013)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    10. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 326624 HGNC: 30268 AceView: RAB37 Ensembl:ENSG00000172794 euGenes: HUgn326624
    ECgene: RAB37 H-InvDB: RAB37

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB37 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB37 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB37 gene:
    Search GeneIP for patents involving RAB37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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