Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RAB37 Gene

protein-coding GIFtS: 51
GCID: GC17P072666

RAB37, member RAS oncogene family

Explore 7 diseases affiliated with
RAB37 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
RAB37, Member RAS Oncogene Family¹ ²
RAB37, Member Of RAS Oncogene Family²
Ras-Related Protein Rab-37²

External Ids:	HGNC: 30268¹	Entrez Gene: 326624²	Ensembl: ENSG00000172794⁷	OMIM: 609956⁵	UniProtKB: Q96AX2³

Export aliases for RAB37 gene to outside databases

Previous GC identifers: GC17P073131 GC17P073264 GC17P073263 GC17P070178 GC17P068076

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RAB37:

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional

background information on Rab proteins, see MIM 179508.(supplied by OMIM, Apr 2006)

Gene Wiki entry for RAB37

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010783.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RAB37 gene promoter:
STAT5B GATA-3 CBF-C HNF-4alpha1 CBF-B CBF-A CP1A NF-Y NF-kappaB1 CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 6): RAB37 promoter sequence

Search SABiosciences Chromatin IP Primers for RAB37

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB37

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.2

RAB37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB37 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P072666: view genomic region (about GC identifiers)

Start:	72,666,717 bp from pter	End:	72,743,474 bp from pter
Size:	76,758 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RAB37_HUMAN, Q96AX2 (See protein sequence)

Recommended Name: Ras-related protein Rab-37 precursor

Size: 223 amino acids; 24815 Da

Subunit: Interacts with RIMS1 (By similarity)

Subcellular location: Cytoplasmic vesicle. Note=Secretory granules (By similarity)

Secondary accessions: A8MXF5 A8MYT0 Q8IWA7

Alternative splicing: 4 isoforms: Q96AX2-1 Q96AX2-2 Q96AX2-3 Q96AX2-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAB37: NX_Q96AX2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96AX2

RAB37 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_001006639.1 NP_001157461.1 NP_001157462.1 NP_783865.1

ENSEMBL proteins:

ENSP00000341354 ENSP00000383934 ENSP00000432086 ENSP00000376391 ENSP00000376390

ENSP00000376389 ENSP00000376388 ENSP00000376387 ENSP00000436563

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Proteins (see all 2): RAB37 OriGene Protein Over-expression Lysate (see all 3): RAB37 OriGene Custom Protein Services for RAB37
	GenScript Custom Purified and Recombinant Proteins Services for RAB37
	Novus Biologicals RAB37 Protein Novus Biologicals RAB37 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RAB37

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IDA	15308636
GO:0016023	cytoplasmic membrane-bounded vesicle	--	--
GO:0030141	secretory granule	IEA	--

RAB37 for ontologies About GeneDecksing

RAB37 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	OriGene Antibodies (see all 9): RAB37 OriGene Custom Antibody Services for RAB37
	GenScript Custom Superior Antibodies Services for RAB37
	Novus Biologicals RAB37 Antibodies
	Search for Antibodies for RAB37 at Abcam
	Uscn Antibodies for RAB37
	Search ThermoFisher Antibodies for RAB37

Assay Products for RAB37:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RAB37
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RAB37

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RAB37 for domains About GeneDecksing

3 InterPro domains/families:

IPR005225 Small_GTP-bd_dom

IPR001806 Small_GTPase

IPR003579 Small_GTPase_Rab_type

Graphical View of Domain Structure for InterPro Entry Q96AX2

ProtoNet protein and cluster: Q96AX2

1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature

UniProtKB/Swiss-Prot: RAB37_HUMAN, Q96AX2

Similarity: Belongs to the small GTPase superfamily. Rab family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 4): RAB37 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RAB37
		8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB37 (see all 14):
		hsa-miR-217 hsa-miR-429 hsa-miR-198 hsa-miR-488 hsa-miR-519c-3p hsa-miR-520a-5p hsa-miR-519a hsa-miR-519b-3p

		SwitchGear 3'UTR luciferase reporter plasmid: RAB37 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAB37 (see all 4) OriGene shRNA RFP: RAB37 OriGene siRNA: RAB37
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAB37

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for RAB37

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAB37 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAB37 (see all 4) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 4): RAB37 (NM_001006638)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB37
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB37

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RAB37
		Search LifeMap BioReagents cell lines for RAB37

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB37

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0005525	GTP binding	IEA	--

RAB37 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for RAB37:

Increased cilium length after

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for RAB37

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5/11 Interacting proteins for RAB37 (Q96AX2³ ENSP00000376389⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RAB5A	P20339³, ENSP00000273047⁴	I2D: score=1 STRING: ENSP00000273047
RIMS1	Q86UR5³, ENSP00000264839⁴	I2D: score=3 STRING: ENSP00000264839
EWSR1	Q01844³, ENSP00000381031⁴	I2D: score=2 STRING: ENSP00000381031
DTX4	Q9Y2E6³	I2D: score=5
PCSK5	Q92824³	I2D: score=5

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007264	small GTPase mediated signal transduction	IEA	--
GO:0015031	protein transport	IEA	--

RAB37 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RAB37
Search CenterWatch for drugs/clinical trials and news about RAB37

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RAB37 gene (5 alternative transcripts):

NM_001006637.1 NM_001006638.2 NM_001163989.1 NM_001163990.1 NM_175738.4

Unigene Cluster for RAB37:

RAB37, member RAS oncogene family

Hs.351413 [show with all ESTs]

Unigene Representative Sequence: NM_175738

15 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000340415(uc002jld.2 uc010dfu.3) ENST00000402449 ENST00000392617(uc002jlc.2)

ENST00000528438 ENST00000392615 ENST00000392614(uc010wrb.2 uc010wrc.2)

ENST00000392613 ENST00000533530 ENST00000527040 ENST00000577548 ENST00000392612(uc010wre.2)

ENST00000392610(uc002jlk.3) ENST00000481224 ENST00000488977 ENST00000531420

miRNA Products:		OriGene 3'-UTR Clone (see all 4): RAB37 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RAB37
		8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB37 (see all 14):
		hsa-miR-217 hsa-miR-429 hsa-miR-198 hsa-miR-488 hsa-miR-519c-3p hsa-miR-520a-5p hsa-miR-519a hsa-miR-519b-3p

		SwitchGear 3'UTR luciferase reporter plasmid: RAB37 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAB37 (see all 4) OriGene shRNA RFP: RAB37 OriGene siRNA: RAB37
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAB37

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAB37 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAB37 (see all 4) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 4): RAB37 (NM_001006638)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB37
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB37

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAB37 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RAB37
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAB37
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAB37

Additional cDNA sequence:

AK057069.1 AK098068.1 AK290202.1 AK296062.1 AK296172.1 AK298033.1 AK303442.1 BC040547.1

13 DOTS entries:

DT.101979436 DT.100698980 DT.40123007 DT.92047341 DT.120912026 DT.100819714 DT.100819720 DT.95372825

DT.70100539 DT.120912024 DT.120912205 DT.40116956 DT.100804565

24/67 AceView cDNA sequences (see all 67):

BQ188402 AK057069 BQ183276 CK299601 AI864721 CR601310 BM921365 BM706070

AK054846 BC016615 BG283602 AK098068 BC040547 AW768344 BU734626 BX328183

AF188522 AL522282 AW270880 BX342475 BX342476 BM981939 BI819064 CD516598

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RAB37 (see all 10) About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4a	·	4b	·	4c	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10a	·	10b	·	10c	^	11a	·	11b	^	12a	·	12b	·	12c	·	12d	·	12e	^	13
SP1:																											-		-		-						-						-		-		-
SP2:									-		-		-		-		-										-		-		-						-
SP3:																											-		-		-						-
SP4:									-		-		-		-		-										-		-		-
SP5:																	-										-		-		-						-

ECgene alternative splicing isoforms for RAB37

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RAB37 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCTGCAGGC

About this image

RAB37 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RAB37 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RAB37

SOURCE GeneReport for Unigene cluster: Hs.351413

SABiosciences Custom PCR Arrays for RAB37

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAB37 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RAB37
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAB37
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAB37

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB37

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RAB37 gene from 8/25 species (see all 25) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100859318¹	ras-related protein Rab-37-like	74.49(n) 77.55(a)		100859318 XM_003642366.1 XP_003642414.1
lizard (Anolis carolinensis)	Reptilia	RAB37⁶	--	83(a)	1 ↔ 1	2(115860490-115879564)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.14110²	Transcribed sequence with weak similarity to protein more	75.21(n)		BX719848.1
zebrafish (Danio rerio)	Actinopterygii	CABZ01102115.1⁶	--	69(a)	1 ↔ 1	12(48932779-48939178)
fruit fly (Drosophila melanogaster)	Insecta	Rab26¹	CG34410-PB	62.09(n) 63.73(a)		40359 NM_001170017.1 NP_001163488.1
worm (Caenorhabditis elegans)	Secernentea	rab-37¹	Protein RAB-37	57.98(n) 57.45(a)		180696 NM_001047829.1 NP_001041294.1
thale cress (Arabidopsis thaliana)	eudicotyledons	RAB8C⁶ RAB8⁶ (see all 5)	RAB GTPase-8 (see all 5)	45(a) 45(a) (see all 5)	possible ortholog possible ortholog (see all 5)	5(883447-885425) 3(19876232-19878519)
rice (Oryza sativa)	Liliopsida	-- -- (see all 4)	ras-related protein, putative, expressed (see all 4)	46(a) 45(a) (see all 4)	possible ortholog possible ortholog (see all 4)	3(34399963-34403616) 7(7741968-7745786)

ENSEMBL Gene Tree for RAB37 (if available)
TreeFam Gene Tree for RAB37 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RAB37 gene

RAB10² RAB19² RAB43² RAB18² RAB26² RAB8A² RAB35² RAB8B²

RAB1B² RAB12² RAB30² RAB1A² RAB13²

18/108 SIMAP similar genes for RAB37 using alignment to 7 protein entries: RAB37_HUMAN (see all proteins) (see all similar genes):

RAB26 rab1b RAB8B RAB10 RAB2A DKFZp313C1541

RAB42 RAB8A RAB39B RAB15 RAB14 RAB4B

RAB11A RAB13 RAB19 RAB2B RAB3C RAB1C

RAB37 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for RAB37
PGOHUM00000261134

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11306402^1,2	C,F	--	68085019(+)	`GTCTCA/-AAAAA`	1	--	int¹ trp³		2		NA	4
rs146726534^1,2		--	72665481(+)	`ATCTCC/TAGATT`	1	--	us2k¹		0	--	--	--	--
rs148865523^1,2		--	72665484(+)	`TCTAGA/GTTGGT`	1	--	us2k¹		0	--	--	--	--
rs182751247^1,2		--	72665695(+)	`TTCTGA/GATTGG`	1	--	us2k¹		0	--	--	--	--
rs115533616^1,2	F,	--	72665720(+)	`TATTTG/ACTCTA`	1	--	us2k¹		1		WA	118
rs143623821^1,2		--	72665811(+)	`GTGAGA/GTTCCA`	1	--	us2k¹		0	--	--	--	--
rs56815987^1,2		--	72665874(+)	`CTCAGA/GAGAAA`	1	--	us2k¹		0	--	--	--	--
rs189794466^1,2		--	72665891(+)	`ATGAGC/TGAGTC`	1	--	us2k¹		0	--	--	--	--
rs182374801^1,2		--	72665926(+)	`TTGAGC/TATAGA`	1	--	us2k¹		0	--	--	--	--
rs115984384^1,2	C,F,	--	72665933(+)	`TAGACA/GACTTT`	1	--	us2k¹		1		WA	118

HapMap Linkage Disequilibrium report for RAB37 (72666717 - 72743474 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for RAB37
4 CNVs: 34522 8852 53066 7171
3 Indels: 43147 61584 102533

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAB37

DNA2.0 Custom Variant and Variant Library Synthesis for RAB37

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RAB37 for disorders           About GeneDecksing

OMIM gene information: 609956    OMIM disorders: --

7 diseases for RAB37:    About MalaCards

hemophagocytic lymphohistiocytosis renal cell carcinoma crohn's disease psoriasis

lung cancer carcinoma neuronitis

Export disorders for RAB37 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RAB37 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with RAB37)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{1, 2} Gevaert K.... Vandekerckhove J. (2003)
Rab37 is a novel mast cell specific GTPase localized to secretory granules. (PubMed id 10722846)^{1, 3} Masuda E.S....Scheller R.H. (2000)
Involvement of TMEM22 overexpression in the growth of renal cell carcinoma cells. (PubMed id 19148500)^{1, 9} Dobashi S....Nakamura Y. (2009)
Integrative analysis of the ubiquitin proteome isolat ed using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)¹ Lopitz-Otsoa F....Rodriguez M.S. (2011)
Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. (PubMed id 20031577)¹ Danik J.S....Ridker P.M. (2009)
Frequent down-regulation of hRAB37 in metastatic tumor by genetic and epigenetic mechanisms in lung cancer. (PubMed id 18687502)¹ Wu C.Y....Hsu M.T. (2009)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)² Zody M.C.... Nusbaum C. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 326624	HGNC: 30268	AceView: RAB37	Ensembl:ENSG00000172794	euGenes: HUgn326624
ECgene: RAB37	H-InvDB: RAB37

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RAB37	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for RAB37	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for RAB37 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RAB37 gene:
Search GeneIP for patents involving RAB37

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	OriGene Antibodies for RAB37		OriGene shRNA RFP for RAB37
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAB37		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAB37
	OriGene Protein Over-expression Lysate for RAB37		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for RAB37		OriGene 3'-UTR Clone for RAB37
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAB37		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAB37
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for RAB37		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for RAB37		OriGene Custom Protein Services for RAB37
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RAB37
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAB37
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB37
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAB37
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAB37
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAB37

	GenScript Custom Purified and Recombinant Proteins Services for RAB37		GenScript cDNA clones with any tag delivered in your preferred vector for RAB37
	GenScript Custom Assay Services for RAB37		GenScript Custom Superior Antibodies Services for RAB37
	GenScript Custom overexpressing Cell Line Services for RAB37		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in RAB37 promoter
	Search Chromatin IP Primers for RAB37
	RT² qPCR Primer Assay in human, mouse, rat RAB37
	GNC Network for RAB37
	SABiosciences Custom PCR Arrays for RAB37

Search Tocris compounds for RAB37

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	RAB37 antibodies
	RAB37 proteins
	RAB37 lysates

	Search for Antibodies for RAB37 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for RAB37
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

RAB37 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RAB37

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB37

	SwitchGear 3'UTR luciferase reporter plasmids for RAB37
	SwitchGear Promoter luciferase reporter plasmids for RAB37

Search ThermoFisher Antibodies for RAB37

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB37

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes RAB37 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

RAB37 Gene

RAB37, member RAS oncogene family

Aliases
for RAB37 gene

Summaries
for RAB37 gene

Genomic Views
for RAB37 gene

Proteins
for RAB37 gene

Protein Domains /
Families
for RAB37 gene

Function
for RAB37 gene

Pathways & Interactions
for RAB37 gene

Drugs & Compounds
for RAB37 gene

Transcripts
for RAB37 gene

Expression
for RAB37 gene

Orthologs
for RAB37 gene

Paralogs
for RAB37 gene

Genomic Variants
for RAB37 gene

Disorders / Diseases
for RAB37 gene

Publications
for RAB37 gene

External Searches for RAB37 gene

Genome Databases showing RAB37 gene

Other Databases showing RAB37 gene

Specialized Databases showing RAB37 gene

Intellectual Property
for RAB37 gene

Products
for RAB37 gene

View Random Gene

Advanced Search

Export list of displayed genes

RAB37 Gene

RAB37, member RAS oncogene family

Aliasesfor RAB37 gene

Summariesfor RAB37 gene

Genomic Viewsfor RAB37 gene

Proteinsfor RAB37 gene

Protein Domains /Familiesfor RAB37 gene

Functionfor RAB37 gene

Pathways & Interactionsfor RAB37 gene

Drugs & Compoundsfor RAB37 gene

Transcriptsfor RAB37 gene

Expression for RAB37 gene

Orthologsfor RAB37 gene

Paralogsfor RAB37 gene

Genomic Variantsfor RAB37 gene

Disorders / Diseasesfor RAB37 gene

Publicationsfor RAB37 gene

External Searches for RAB37 gene

Genome Databases showing RAB37 gene

Other Databases showing RAB37 gene

Specialized Databases showing RAB37 gene

Intellectual Propertyfor RAB37 gene

Productsfor RAB37 gene

View Random Gene

Aliases
for RAB37 gene

Summaries
for RAB37 gene

Genomic Views
for RAB37 gene

Proteins
for RAB37 gene

Protein Domains /
Families
for RAB37 gene

Function
for RAB37 gene

Pathways & Interactions
for RAB37 gene

Drugs & Compounds
for RAB37 gene

Transcripts
for RAB37 gene

Expression
for RAB37 gene

Orthologs
for RAB37 gene

Paralogs
for RAB37 gene

Genomic Variants
for RAB37 gene

Disorders / Diseases
for RAB37 gene

Publications
for RAB37 gene

Intellectual Property
for RAB37 gene

Products
for RAB37 gene