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Aliases & Descriptions for RAB35
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| H-ray 1, 2 | | RAB1C 2, 3 | | RAY 2, 3 | | Rab-1C 3 |
| | | Descriptions |
|---|
| GTP-binding protein RAY 3 | | RAB35, member RAS oncogene family 2 | | ras-related protein rab-1c (GTP-binding protein ray) 2 |
|
| | Search outside databases for aliases for RAB35 genePrevious GC identifers: GC12M119405 GC12M120060 GC12M120315 GC12M118944 |
Summaries for RAB35(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: RAB35_HUMAN, Q15286Function: Possesses GTPase activityGene Wiki entry for RAB35 |
Genomic Location for RAB35
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the RAB35 gene 
Entrez Gene cytogenetic band: 12q24.31 Ensembl cytogenetic band: 12q24.23 HGNC cytogenetic band: 12q24RAB35 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M118995:
(about GC identifiers)
Start:
|
119,017,286 bp from pter |
End:
|
119,038,982 bp from pter |
Size:
|
21,697 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000012.10 NT_009775.16
| Proteins for RAB35
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: RAB35_HUMAN, Q15286 (See
protein sequence)Recommended Name: Ras-related protein Rab-35 Size: 201 amino acids; 23025 Da
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IVPost-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_006852.1
ENSEMBL proteins: ENSP00000229340
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: RAB35 
5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6
): About this table
Antibodies for RAB35: Assays for RAB35: | Protein
Domains/ Families for RAB35(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q15286
ProtoNet protein and cluster: Q15286 1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature
UniProtKB/Swiss-Prot: RAB35_HUMAN, Q15286Similarity: Belongs to the small GTPase superfamily. Rab family | Gene Function for RAB35
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006861
Applied Biosystems Silencer® siRNAs for RAB35
Sigma-Aldrich siRNA for RAB35  Sigma-Aldrich shRNA for RAB35  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006861                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_006861                                  untagged cDNA clone in CMV expression vector: NM_006861 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_006861
UniProtKB/Swiss-Prot: RAB35_HUMAN, Q15286Function: Possesses GTPase activityGenatlas biochemistry entry for RAB35:RAB35,RAS oncogene superfamily member 35,ubiquitously expressed4 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for RAB35
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
5/10 Interacting proteins for RAB35 (Q152862) via UniProtKB, MINT, and/or STRING (see all 10
)About this table
5 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for RAB35(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|  |
Enzo Life Sciences drugs & compounds for RAB35 |
Browse Tocris compounds for RAB35
|
Transcripts for RAB35(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006861
Sigma-Aldrich siRNA for RAB35  Sigma-Aldrich shRNA for RAB35  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_006861 REFSEQ mRNAs for RAB35 gene: NM_006861.4
Applied Biosystems TaqMan ® Gene Expression Assays: NM_006861               OriGene GFP tagged cDNA clone in CMV expression vector: NM_006861                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_006861                                  untagged cDNA clone in CMV expression vector: NM_006861  Additional cDNA sequence: AF498960.1 AK001309.2 AK125543.1 AK298391.1 AK300127.1 AK304620.1 AK312538.1 BC015931.2 BC017753.1 BT020024.1 CR536486.1 CR541683.1 X79781.1 12 DOTS entries: DT.309459 DT.91960376 DT.75159901 DT.100027022 DT.121137122 DT.121137165 DT.91751452 DT.97774884 DT.100711889 DT.100757062 DT.100782112 DT.95278290 11 AceView cDNA sequences:NM_006861 AF498960 AK001309 BC017753 CR622981 CR536486 CR541683 CR623183 X79781 BC015931 AK125543
highest scoring ESTs for RAB35:X79781 AF498960 AK125543 BC015931 BE939625 AA423837 AA423875 AA877614 AK001309 AL534849 Unigene Cluster for RAB35: RAB35, member RAS oncogene family Hs.524788 [show with all ESTs]Unigene Representative Sequence: NM_006861
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for RAB35
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | · | 8c | |
| SP1: | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | - |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | - |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP5: | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for RAB35
1 Ensembl transcript including schematic representation: ENST00000229340
|
Expression for RAB35
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| RAB35 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for RAB35
1 / 2 / 3 10 probe-sets matching RAB35 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: AATGGGGGTT
SOURCE GeneReport for Unigene cluster: Hs.524788
Expression variation in blood from EXPOLDB for RAB35 |
Orthologs for RAB35
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for RAB35 gene from 5/12 species (see all 12
)
About this table Species with no ortholog for RAB35
ENSEMBL Gene Tree for RAB35 | Paralogs for RAB35(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for RAB35 gene
- RAB252 RAB11A2 RAB11B2
|
SNPs/Variants for RAB35(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for RAB35 (up to first 250kb)
|
Disorders & Mutations for RAB35
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 604199
|
Medical News for RAB35(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for RAB35 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10 PubMed articles for RAB35 gene: |
Search for RAB35
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RAB35
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing RAB35
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAB35(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for RAB35(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for RAB35:

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Incremental update: 13 Oct 2009
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