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Aliases & Descriptions for RAB34
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases OTTHUMP00000163525 2 RAB39 1 , 2 , 3 RAH 1 , 2 , 3 , 5 Rab-39 3
Descriptions RAB34, member RAS oncogene family 2 Ras-related protein RAB34 2 Ras-related protein Rah 3
Search outside databases for aliases for RAB34 genePrevious GC identifers: GC17M026887 GC17M028941 GC17M027186
Summaries for RAB34 (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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EntrezGene summary for RAB34 : RAB proteins, like RAB34, are small GTPases that regulate vesicle budding, docking, and fusionalong endocytosis and exocytosis pathways (Chen et al., 2003 [PubMed 12684051]).[supplied by OMIM] UniProtKB/Swiss-Prot: RAB34_HUMAN, Q9BZG1 Function : Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region(By similarity)
Gene Wiki entry for RAB34
Genomic Location for RAB34
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the RAB34 gene Entrez Gene cytogenetic band: 17q11.2 Ensembl cytogenetic band: 17q11.2 HGNC cytogenetic band: 17q11.2 RAB34 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17M024065:
(about GC identifiers )
Start:
24,065,429 bp from pter
End:
24,069,328 bp from pter
Size:
3,900 bases
Orientation:
minus strand
RefSeq DNA sequence: NC_000017.9 NT_010799.14 Proteins for RAB34
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: RAB34_HUMAN, Q9BZG1 (See
protein sequence )Recommended Name: Ras-related protein Rab-34 Size : 259 amino acids; 29044 Da
Subunit : Interacts with RILP
Subcellular location : Cytoplasm (By similarity). Golgi apparatus (By similarity). Note=Associateswith the Golgi complex (By similarity)
Secondary accessions : Q5BJE6 Q8NCJ8 Q96AR4Alternative splicing : 2 isoforms : Q9BZG1-1 Q9BZG1-2
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (5 alternative transcripts):
NP_001136096.2 NP_001136097.2 NP_001138414.1 NP_001138415.1 NP_114140.4 ENSEMBL proteins: ENSP00000301043 ENSP00000378663 ENSP00000378664 ENSP00000226259 ENSP00000378666 Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 2 Gene Ontology (GO) cellular component terms (links to tree view) :
About this table Antibodies for RAB34: Assays for RAB34:
Protein
Domains/ Families for RAB34(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9BZG1 ProtoNet protein and cluster: Q9BZG1
1 Blocks protein family : IPB001806 Transforming protein P21 RAS signature UniProtKB/Swiss-Prot: RAB34_HUMAN, Q9BZG1 Similarity : Belongs to the small GTPase superfamily. Rab family
Gene Function for RAB34
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
from Invitrogen ,
Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 7 ): NR_024575 Applied Biosystems Silencer ® siRNAs for RAB34 Sigma-Aldrich siRNA for RAB34 Sigma-Aldrich shRNA for RAB34 Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 5 ): NM_001142624                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 5 ): NM_001142624                                  untagged cDNA clones in CMV expression vector (see all 5 ): NM_001142624  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001144943 UniProtKB/Swiss-Prot: RAB34_HUMAN, Q9BZG1 Function : Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region(By similarity)
1 MGI phenotypic allele for Rab34 (no phenotypes)2 Gene Ontology (GO) molecular function terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0000166 nucleotide binding
IEA -- GO:0005525 GTP binding
IEA --
About this table
Pathways & Interactions for RAB34
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for RAB34 (Your Favorite Gene powered by Ingenuity) Gene Network CentralTM Interacting Genes and Proteins Network for RAB34 3 Interacting proteins for RAB34 (ENSP00000301043 3 ) via UniProtKB, MINT, and/or STRING About this table 2 Gene Ontology (GO) biological process terms (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0007264 small GTPase mediated signal transduction
IEA -- GO:0015031 protein transport
IEA --
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Drugs & Compounds for RAB34 (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Enzo Life Sciences drugs & compounds for RAB34
Browse Tocris compounds for RAB34
Transcripts for RAB34(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 7 ): NR_024575 Sigma-Aldrich siRNA for RAB34 Sigma-Aldrich shRNA for RAB34 Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001142624 NM_001142625 NM_031934
REFSEQ mRNAs for RAB34 gene (5 alternative transcripts): NM_001142624.2 NM_001142625.2 NM_001144942.1 NM_001144943.1 NM_031934.5
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001142624 NM_001142625 NM_031934
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 5 ): NM_001142624                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 5 ): NM_001142624                                  untagged cDNA clones in CMV expression vector (see all 5 ): NM_001142624  
Additional cDNA sequence: AF322067.1 AF327350.1 AJ277106.1 AK027312.1 AK074689.1 AK297850.1 AK304633.1 BC016841.1 BC066904.1 BC091510.1 BT006702.1 CR596043.1 CR600820.1 CR612137.1 CR612854.1 CR613380.1 CR614283.1 CR620011.1 CR622817.1
24/29 DOTS entries (see all 29
): DT.92443118 DT.91691857 DT.102843818 DT.95197976 DT.100829142 DT.92443115 DT.100031106 DT.95069403 DT.100031110 DT.95368709 DT.120910257 DT.100883974 DT.100883981 DT.100883979 DT.100883985 DT.120910258 DT.100883977 DT.100883978 DT.92443119 DT.99988328 DT.100883972 DT.100883983 DT.120910261 DT.120910274
24/476 AceView cDNA sequences (see all 476
):BP354410 CR622817 BM705481 BM459933 BQ674626 AW793261 BU686336 AK027312 CD518942 BU175922 BC016841 BU526908 AW769494 BU856687 AI082082 BM767908 AA991593 CF127918 BQ218224 CB125701 CF126767 AK074689 BU688067 BI768064
highest scoring ESTs for RAB34 :AF327350 AI189282 AI205145 AJ277106 AK027312 AK074689 AL547914 AL550699 AL556234 AL564667
Unigene Cluster for RAB34: RAB34, member RAS oncogene family Hs.301853 [show with all ESTs ] Unigene Representative Sequence: NM_031934 GeneLoc Exon Structure 5/21 Alternative Splicing Database (ASD) splice patterns (SP) for RAB34 (see all 21
) ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g · 2h · 2i · 2j · 2k · 2l ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · SP1 :         -   -   -   -   -   -   -   -         -     -   -           -       SP2 :                               -     -   -           -       SP3 :                               -     -   -           -       SP4 :                               -     -   -           -       SP5 :         -   -   -   -   -   -   -   -         -     -   -           -      
ExUns: 8c ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c · 12d SP1 :                     SP2 :                     SP3 : -   -                   SP4 :       -   -   -   -         SP5 :                    
About this scheme ECgene alternative splicing isoforms for RAB34 5 Ensembl transcripts including schematic representations : ENST00000301043
ENST00000395242
ENST00000395243
ENST00000353676
ENST00000395245
Expression for RAB34
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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RAB34 expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for RAB34 1 / 2 / 3
4 probe-sets matching RAB34 gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: CTAGTCACTTSOURCE GeneReport for Unigene cluster: Hs.301853
Orthologs for RAB34
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for RAB34 gene from 5/10 species (see all 10
)
About this table Species with no ortholog for RAB34 ENSEMBL Gene Tree for RAB34 Paralogs for RAB34 (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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Paralogs for RAB34 gene RAB36 2
SNPs/Variants for RAB34 (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for RAB34 (up to first 250kb)
Disorders & Mutations for RAB34
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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OMIM: 610917
Medical News for RAB34 (Possibly Related Articles in
Doctor's Guide )
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--
Publications for RAB34 (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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10/19 PubMed articles for RAB34 gene (see all 19
):
Search for RAB34
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing RAB34
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing RAB34
(According to HUGE )
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--
Specialized Databases showing RAB34 (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for RAB34 (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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