Aliases for RAB34 Gene
External Ids for RAB34 Gene
Previous GeneCards Identifiers for RAB34 Gene
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. This gene overlaps and shares exon structure with the nine-amino acid residue-repeats (NARR) gene, which encodes a functionally distinct nucleolar protein from a different reading frame. [provided by RefSeq, Jan 2012]
GeneCards Summary for RAB34 Gene
RAB34 (RAB34, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB34 include low compliance bladder. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and guanyl nucleotide binding. An important paralog of this gene is RAB41.
UniProtKB/Swiss-Prot for RAB34 Gene
Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.