External Ids for RAB33B Gene
Previous GeneCards Identifiers for RAB33B Gene
Small GTP-binding proteins of the RAB family, such as RAB33B, play important roles at defined steps of vesicular transport in protein secretion and the endocytosis pathway (Zheng et al., 1998 [PubMed 9512502]).[supplied by OMIM, Feb 2010]
GeneCards Summary for RAB33B Gene
RAB33B (RAB33B, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB33B include Smith-Mccort Dysplasia 2 and Smith-Mccort Dysplasia. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Golgi-to-ER retrograde transport. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB33A.
UniProtKB/Swiss-Prot for RAB33B Gene
Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation.