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RAB33B Gene

protein-coding   GIFtS: 56
GCID: GC04P140374

RAB33B, Member RAS Oncogene Family

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB33B, Member RAS Oncogene Family1 2
SMC22 5
Ras-Related Protein Rab-33B2

External Ids:    HGNC: 160751   Entrez Gene: 834522   Ensembl: ENSG000001720077   OMIM: 6059505   UniProtKB: Q9H0823   

Export aliases for RAB33B gene to outside databases

Previous GC identifers: GC04P141280 GC04P140674 GC04P140841 GC04P140952 GC04P140732 GC04P136104


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB33B Gene:
Small GTP-binding proteins of the RAB family, such as RAB33B, play important roles at defined steps of vesicular
transport in protein secretion and the endocytosis pathway (Zheng et al., 1998 (PubMed 9512502)).(supplied by
OMIM, Feb 2010)

GeneCards Summary for RAB33B Gene:
RAB33B (RAB33B, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB33B include smith mccort dysplasia, and smith-mccort dysplasia 2. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAB35.

UniProtKB/Swiss-Prot: RB33B_HUMAN, Q9H082
Function: Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It
is involved in autophagy, acting as a modulator of autophagosome formation

Gene Wiki entry for RAB33B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NC_018915.2  NT_016354.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB33B gene promoter:
         STAT1   Sp1   p53   FOXD1   STAT1beta   Egr-4   STAT1alpha   E47   STAT3   ZID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB33B promoter sequence
   Search Chromatin IP Primers for RAB33B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB33B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q28   Ensembl cytogenetic band:  4q31.1   HGNC cytogenetic band: 4q28

RAB33B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB33B gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P140374:  view genomic region     (about GC identifiers)

Start:
140,374,386 bp from pter      End:
140,397,763 bp from pter
Size:
23,378 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RB33B_HUMAN, Q9H082 (See protein sequence)
Recommended Name: Ras-related protein Rab-33B  
Size: 229 amino acids; 25718 Da
Subunit: Interacts with ATG16L; the interaction is important for autophagosome formation (By similarity)
Secondary accessions: B2R987 Q4W5B0

Explore the universe of human proteins at neXtProt for RAB33B: NX_Q9H082

Explore proteomics data for RAB33B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB33B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112586.1  
    ENSEMBL proteins: 
     ENSP00000306496  

    RAB33B Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for RAB33B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9H082

    ProtoNet protein and cluster: Q9H082

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RB33B_HUMAN, Q9H082
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RAB33B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RB33B_HUMAN, Q9H082
    Function: Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It
    is involved in autophagy, acting as a modulator of autophagosome formation

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005515protein binding ----
    GO:0005525GTP binding IEA--
         
    RAB33B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB33B:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB33B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB33B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAB33B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB33B

    miRNA
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    miRTarBase miRNAs that target RAB33B:
    hsa-mir-100-5p (MIRT048429)

    Block miRNA regulation of human, mouse, rat RAB33B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB33B (see all 26):
    hsa-miR-623 hsa-miR-520d-5p hsa-miR-128 hsa-miR-944 hsa-miR-340 hsa-miR-548l hsa-miR-9 hsa-miR-499-5p
    SwitchGear 3'UTR luciferase reporter plasmidRAB33B 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RAB33B
    Predesigned siRNA for gene silencing in human, mouse, rat RAB33B

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    GenScript: all cDNA clones in your preferred vector: RAB33B (NM_031296)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB33B

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB33B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RB33B_HUMAN, Q9H082: Golgi apparatus membrane; Lipid-anchor (By similarity). Golgi apparatus, cis-Golgi network
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    cytosol3
    cytoskeleton1
    endosome1
    extracellular1
    nucleus1
    vacuole1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005794Golgi apparatus IDA--

    RAB33B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB33B About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB33B
        Epithelial Tight Junctions


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB33B
    Interactions:

        Search GeneGlobe Interaction Network for RAB33B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB33B (Q9H0823 ENSP000003064964) via UniProtKB, MINT, STRING, and/or I2D (see all 79)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACVR1Q047713, ENSP000002636404I2D: score=3 STRING: ENSP00000263640
    GABARAPL1Q9H0R83, ENSP000002664584I2D: score=1 STRING: ENSP00000266458
    RABGEF1Q9UJ413, ENSP000002849574I2D: score=1 STRING: ENSP00000284957
    GOLGA2Q083793, ENSP000004160974I2D: score=2 STRING: ENSP00000416097
    RABEP1Q152763, ENSP000002624774I2D: score=2 STRING: ENSP00000262477
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0006914autophagy IEA--
    GO:0007165signal transduction ----

    RAB33B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB33B (RB33B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAB33B gene: 
    NM_031296.1  

    Unigene Cluster for RAB33B:

    RAB33B, member RAS oncogene family
    Hs.591679  [show with all ESTs]
    Unigene Representative Sequence: AL136904
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000507271 ENST00000305626(uc003ihv.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RAB33B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB33B (see all 26):
    hsa-miR-623 hsa-miR-520d-5p hsa-miR-128 hsa-miR-944 hsa-miR-340 hsa-miR-548l hsa-miR-9 hsa-miR-499-5p
    SwitchGear 3'UTR luciferase reporter plasmidRAB33B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RAB33B
    Predesigned siRNA for gene silencing in human, mouse, rat RAB33B
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    OriGene ORF clones in mouse, rat for RAB33B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAB33B (NM_031296)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB33B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB33B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RAB33B
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB33B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB33B
      QuantiTect SYBR Green Assays in human, mouse, rat RAB33B
      QuantiFast Probe-based Assays in human, mouse, rat RAB33B

    Additional mRNA sequence: 

    AF350420.1 AK313685.1 AL136904.1 BC036064.1 BC111977.1 

    3 DOTS entries:

    DT.97838286  DT.75100804  DT.70101003 

    Selected AceView cDNA sequences (see all 50):

    CF994555 AI889871 BM893637 Z36966 T30461 AL136904 BM931688 BM893798 
    NM_031296 CK823289 BF194896 AU280090 BQ723710 AA577079 BM675710 BX505064 
    BU754295 CK823290 BX478341 BM795187 AV724529 CD511702 BX951518 AF350420 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB33B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTTCAATA
    RAB33B Expression
    About this image


    RAB33B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
    RAB33B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB33B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591679
        Custom PCR Arrays for RAB33B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB33B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RAB33B gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab33b1 , 5 RAB33B, member of RAS oncogene family1, 5 87.48(n)1
    94.76(a)1
      3 (22.49 cM)5
    193381  NM_016858.21  NP_058554.11 
     514839665 
    chicken
    (Gallus gallus)
    Aves RAB33B1 RAB33B, member RAS oncogene family 83.99(n)
    95.59(a)
      422441  NM_001008466.1  NP_001008466.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB33B6
    RAB33B, member RAS oncogene family
    90(a)
    1 ↔ 1
    5(120263718-120268242)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC059345.12   -- 76.79(n)    BC059345.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.111302 Transcribed sequence with weak similarity to protein more 72.59(n)    BI883463.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab9D6
    Rab GTPase 9D
    31(a)
    many ↔ many
    X(10483122-10484018)
    worm
    (Caenorhabditis elegans)
    Secernentea rab-331 rab-33 58.24(n)
    60.11(a)
      176470  NM_066913.3  NP_499314.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPT11(YNL304W)4 Rab family GTPase that interacts with the C-terminal more   --   14(60297-61550) 855412  NP_014095.2 


    ENSEMBL Gene Tree for RAB33B (if available)
    TreeFam Gene Tree for RAB33B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB33B gene
    RAB352  RAB33A2  RAB182  
    Selected SIMAP similar genes for RAB33B using alignment to 2 protein entries:     RB33B_HUMAN (see all proteins) (see all similar genes):
    RAB33A    DKFZp686J06205    DKFZp686J07132    RAB19    RAB30    RAB4B
    RANP1    RAB43    RAB8B    rab1b    RAB15    RAB10
    RAB11B    RAB4A    RAB8A    KRAS    RAB17    RAB37

    RAB33B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB33B (see all 500)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0688544
    Smith-McCort dysplasia 2 (SMC2)4--see VAR_0688542 K Q mis40--------
    VAR_0688554
    Smith-McCort dysplasia 2 (SMC2)4--see VAR_0688552 N K mis40--------
    rs1407378481,2
    --140373002(+) TTACAA/TGTTCA 1 -- us2k10--------
    rs762721221,2
    F--140373050(+) ATGAAC/TAGTCA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs117357761,2
    C,F,A,H--140373051(+) TGAACG/AGTCAA 1 -- us2k120Minor allele frequency- A:0.26NS EA NA WA CSA 1154
    rs11426271,2
    C,F,O,A,H--140373081(-) AAGAAT/GGGATG 1 -- us2k124Minor allele frequency- G:0.16MN NA EA NS CSA WA 2554
    rs1893431011,2
    --140373560(+) AATGAC/TGTTAG 1 -- us2k10--------
    rs1456348841,2
    --140373574(+) TTTTCA/TCCATC 1 -- us2k10--------
    rs1808977221,2
    --140373648(+) GATTCC/GCTCCT 1 -- us2k10--------
    rs1159239541,2
    F--140373699(+) CGAGGC/GTCTCT 1 -- us2k11Minor allele frequency- G:0.03NA 120

    HapMap Linkage Disequilibrium report for RAB33B (140374386 - 140397763 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for RAB33B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv830085CNV Loss17160897
    nsv830084CNV Loss17160897

    Human Gene Mutation Database (HGMD): RAB33B
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB33B
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB33B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605950   
    OMIM disorders: 615222  
    UniProtKB/Swiss-Prot: RB33B_HUMAN, Q9H082
  • Smith-McCort dysplasia 2 (SMC2) [MIM:615222]: A rare autosomal recessive osteochondrodysplasia with
    skeletal features identical to those of Dyggve-Melchior-Clausen syndrome, but with normal intelligence and no
    microcephaly. It is characterized by short limbs and trunk with barrel-shaped chest. The radiographic phenotype
    includes platyspondyly, generalized abnormalities of the epiphyses and metaphyses, and a distinctive lacy
    appearance of the iliac crest. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 10 diseases for RAB33B:    
    About MalaCards
    smith mccort dysplasia    smith-mccort dysplasia 2    dyggve-melchior-clausen syndrome    transient cerebral ischemia
    osteochondrodysplasia    microcephaly    ischemia    cerebritis
    multiple myeloma    myeloma

    1 disease from the University of Copenhagen DISEASES database for RAB33B:
    Spondyloepimetaphyseal dysplasia

    RAB33B for disorders           About GeneDecksing

    Genetic Association Database (GAD): RAB33B

    Export disorders for RAB33B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB33B gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with RAB33B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutation in RAB33B, which encodes a regulator of retrograde Golgi transport, defines a second Dyggve--Melchior--Clausen locus. (PubMed id 22652534)1, 2 Alshammari M.J.... Alkuraya F.S. (J. Med. Genet. 2012)
    2. Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. (PubMed id 18448665)1, 2 Itoh T.... Fukuda M. (Mol. Biol. Cell 2008)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. A novel RAB33B mutation in Smith-McCort dysplasia. (PubMed id 23042644)2 Dupuis N.... Ghouzzi V.E. (Hum. Mutat. 2013)
    8. Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase. (PubMed id 23091056)1 Pusapati G.V....Pfeffer S.R. (J. Biol. Chem. 2012)
    9. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83452 HGNC: 16075 AceView: RAB33B Ensembl:ENSG00000172007 euGenes: HUgn83452
    ECgene: RAB33B H-InvDB: RAB33B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB33B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB33B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB33B gene:
    Search GeneIP for patents involving RAB33B

    GeneCards and IP:
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