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Aliases for RAB33A Gene

Aliases for RAB33A Gene

  • RAB33A, Member RAS Oncogene Family 2 3 5
  • Small GTP-Binding Protein S10 3 4
  • RabS10 3 4

External Ids for RAB33A Gene

Previous GeneCards Identifiers for RAB33A Gene

  • GC0XP123951
  • GC0XP126151
  • GC0XP127250
  • GC0XP128011
  • GC0XP129031
  • GC0XP129133
  • GC0XP129305
  • GC0XP118701

Summaries for RAB33A Gene

Entrez Gene Summary for RAB33A Gene

  • The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport. [provided by RefSeq, Jul 2008]

GeneCards Summary for RAB33A Gene

RAB33A (RAB33A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB1A.

Gene Wiki entry for RAB33A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB33A Gene

Genomics for RAB33A Gene

Regulatory Elements for RAB33A Gene

Enhancers for RAB33A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RAB33A on UCSC Golden Path with GeneCards custom track

Promoters for RAB33A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RAB33A on UCSC Golden Path with GeneCards custom track

Genomic Location for RAB33A Gene

130,171,649 bp from pter
130,184,870 bp from pter
13,222 bases
Plus strand

Genomic View for RAB33A Gene

Genes around RAB33A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RAB33A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RAB33A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB33A Gene

Proteins for RAB33A Gene

  • Protein details for RAB33A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ras-related protein Rab-33A
    Protein Accession:
    Secondary Accessions:
    • Q5JUZ6
    • Q92465

    Protein attributes for RAB33A Gene

    237 amino acids
    Molecular mass:
    26593 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RAB33A Gene

Proteomics data for RAB33A Gene at MOPED

Post-translational modifications for RAB33A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAB33A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAB33A Gene

Domains & Families for RAB33A Gene

Gene Families for RAB33A Gene

Suggested Antigen Peptide Sequences for RAB33A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the small GTPase superfamily. Rab family.
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RAB33A: view

Function for RAB33A Gene

Molecular function for RAB33A Gene

GENATLAS Biochemistry:
RAB33A,Ras oncogene superfamily member,expressed in brain
genes like me logo Genes that share phenotypes with RAB33A: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RAB33A Gene

Localization for RAB33A Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB33A Gene

Cell membrane; Lipid-anchor; Cytoplasmic side.

Subcellular locations from

Jensen Localization Image for RAB33A Gene COMPARTMENTS Subcellular localization image for RAB33A gene
Compartment Confidence
plasma membrane 4
cytosol 3
nucleus 2
extracellular 1
golgi apparatus 1

No data available for Gene Ontology (GO) - Cellular Components for RAB33A Gene

Pathways & Interactions for RAB33A Gene

genes like me logo Genes that share pathways with RAB33A: view

Pathways by source for RAB33A Gene

1 Qiagen pathway for RAB33A Gene

Gene Ontology (GO) - Biological Process for RAB33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
GO:2000785 regulation of autophagosome assembly IBA --
genes like me logo Genes that share ontologies with RAB33A: view

No data available for SIGNOR curated interactions for RAB33A Gene

Drugs & Compounds for RAB33A Gene

No Compound Related Data Available

Transcripts for RAB33A Gene

mRNA/cDNA for RAB33A Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(58) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB33A Gene

RAB33A, member RAS oncogene family:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RAB33A Gene

No ASD Table

Relevant External Links for RAB33A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB33A Gene

mRNA expression in normal human tissues for RAB33A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RAB33A Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x4.9).

Protein differential expression in normal tissues from HIPED for RAB33A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (57.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAB33A Gene

SOURCE GeneReport for Unigene cluster for RAB33A Gene Hs.654356

mRNA Expression by UniProt/SwissProt for RAB33A Gene

Tissue specificity: Expressed only in lymphoid cell lines.
genes like me logo Genes that share expression patterns with RAB33A: view

Protein tissue co-expression partners for RAB33A Gene

- Elite partner

Primer Products

Orthologs for RAB33A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RAB33A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC784703 35
  • 95.5 (n)
  • 99.16 (a)
RAB33A 36
  • 99 (a)
(Canis familiaris)
Mammalia RAB33A 35
  • 96.48 (n)
  • 100 (a)
RAB33A 36
  • 100 (a)
(Mus musculus)
Mammalia Rab33a 35
  • 92.26 (n)
  • 98.31 (a)
Rab33a 16
Rab33a 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Rab33a 35
  • 93.11 (n)
  • 99.16 (a)
(Monodelphis domestica)
Mammalia RAB33A 36
  • 86 (a)
(Pan troglodytes)
Mammalia RAB33A 36
  • 99 (a)
(Gallus gallus)
Aves RAB33A 35
  • 82.94 (n)
  • 88.26 (a)
RAB33A 36
  • 85 (a)
(Anolis carolinensis)
Reptilia RAB33A 36
  • 86 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rab33a 35
  • 65.89 (n)
  • 71.5 (a)
(Danio rerio)
Actinopterygii rab33a 35
  • 72.12 (n)
  • 78.76 (a)
rab33a 36
  • 76 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rab9Fb 36
  • 32 (a)
(Caenorhabditis elegans)
Secernentea rab-33 36
  • 36 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SEC4 36
  • 36 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8759 36
  • 55 (a)
Species with no ortholog for RAB33A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RAB33A Gene

Gene Tree for RAB33A (if available)
Gene Tree for RAB33A (if available)

Paralogs for RAB33A Gene

genes like me logo Genes that share paralogs with RAB33A: view

Variants for RAB33A Gene

Sequence variations from dbSNP and Humsavar for RAB33A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
VAR_006849 -
rs748090467 -- 130,178,273(+) TGATT(A/G)CACTG intron-variant
rs748224283 -- 130,171,128(+) GTAAC(A/G)GAAAC upstream-variant-2KB
rs748360913 -- 130,176,271(+) GGGGT(-/GT)GTGTG intron-variant
rs748606991 -- 130,176,580(+) TTGGA(A/G)GCTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RAB33A Gene

Variant ID Type Subtype PubMed ID
nsv528290 CNV Gain 19592680

Variation tolerance for RAB33A Gene

Residual Variation Intolerance Score: 35.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.66; 31.75% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RAB33A Gene

Disorders for RAB33A Gene

Relevant External Links for RAB33A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RAB33A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAB33A Gene

Publications for RAB33A Gene

  1. Molecular cloning of a cDNA encoding a novel small GTP-binding protein. (PMID: 7688322) Koda T. … Kakinuma M. (FEBS Lett. 1993) 2 3 4 67
  2. A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae. (PMID: 9512502) Zheng J.Y. … Kakinuma M. (J. Cell. Sci. 1998) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Protein interactions of the transcription factor Hoxa1. (PMID: 23088713) Lambert B. … Rezsohazy R. (BMC Dev. Biol. 2012) 3
  5. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3

Products for RAB33A Gene

Sources for RAB33A Gene