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Aliases for RAB33A Gene

Aliases for RAB33A Gene

  • RAB33A, Member RAS Oncogene Family 2 3
  • Small GTP-Binding Protein S10 3 4
  • RabS10 3 4
  • Ras-Related Protein Rab-33A 3

External Ids for RAB33A Gene

Previous GeneCards Identifiers for RAB33A Gene

  • GC0XP123951
  • GC0XP126151
  • GC0XP127250
  • GC0XP128011
  • GC0XP129031
  • GC0XP129133
  • GC0XP129305
  • GC0XP118701

Summaries for RAB33A Gene

Entrez Gene Summary for RAB33A Gene

  • The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport. [provided by RefSeq, Jul 2008]

GeneCards Summary for RAB33A Gene

RAB33A (RAB33A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB18.

Gene Wiki entry for RAB33A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB33A Gene

Genomics for RAB33A Gene

Regulatory Elements for RAB33A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RAB33A Gene

Start:
130,171,649 bp from pter
End:
130,184,870 bp from pter
Size:
13,222 bases
Orientation:
Plus strand

Genomic View for RAB33A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB33A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB33A Gene

Proteins for RAB33A Gene

  • Protein details for RAB33A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14088-RB33A_HUMAN
    Recommended name:
    Ras-related protein Rab-33A
    Protein Accession:
    Q14088
    Secondary Accessions:
    • Q5JUZ6
    • Q92465

    Protein attributes for RAB33A Gene

    Size:
    237 amino acids
    Molecular mass:
    26593 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RAB33A Gene

Proteomics data for RAB33A Gene at MOPED

Post-translational modifications for RAB33A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAB33A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for RAB33A Gene

Domains for RAB33A Gene

Gene Families for RAB33A Gene

HGNC:
  • RAB :RAB, member RAS oncogene

Suggested Antigen Peptide Sequences for RAB33A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q14088

UniProtKB/Swiss-Prot:

RB33A_HUMAN :
  • Q14088
Family:
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RAB33A: view

Function for RAB33A Gene

Molecular function for RAB33A Gene

GENATLAS Biochemistry: RAB33A,Ras oncogene superfamily member,expressed in brain

Gene Ontology (GO) - Molecular Function for RAB33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity TAS 7688322
GO:0005515 protein binding IPI 16189514
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with RAB33A: view

Phenotypes for RAB33A Gene

genes like me logo Genes that share phenotypes with RAB33A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RAB33A Gene

Localization for RAB33A Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB33A Gene

Cell membrane; Lipid-anchor; Cytoplasmic side.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RAB33A Gene COMPARTMENTS Subcellular localization image for RAB33A gene
Compartment Confidence
plasma membrane 5
cytosol 3
nucleus 2
extracellular 1
golgi apparatus 1
vacuole 1

Gene Ontology (GO) - Cellular Components for RAB33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005737 cytoplasm --
GO:0005794 Golgi apparatus IBA --
GO:0005886 plasma membrane IEA --
genes like me logo Genes that share ontologies with RAB33A: view

Pathways for RAB33A Gene

genes like me logo Genes that share pathways with RAB33A: view

Pathways by source for RAB33A Gene

1 Qiagen pathway for RAB33A Gene

Gene Ontology (GO) - Biological Process for RAB33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006184 obsolete GTP catabolic process --
GO:0006886 intracellular protein transport IBA --
GO:0006913 nucleocytoplasmic transport --
GO:0007165 signal transduction --
GO:0007264 small GTPase mediated signal transduction --
genes like me logo Genes that share ontologies with RAB33A: view

Transcripts for RAB33A Gene

mRNA/cDNA for RAB33A Gene

(58) Selected AceView cDNA sequences:
(7) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB33A Gene

RAB33A, member RAS oncogene family:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RAB33A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RAB33A Gene

No ASD Table

Relevant External Links for RAB33A Gene

GeneLoc Exon Structure for
RAB33A
ECgene alternative splicing isoforms for
RAB33A

Expression for RAB33A Gene

mRNA expression in normal human tissues for RAB33A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RAB33A Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (4.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAB33A Gene

SOURCE GeneReport for Unigene cluster for RAB33A Gene Hs.654356

mRNA Expression by UniProt/SwissProt for RAB33A Gene

Q14088-RB33A_HUMAN
Tissue specificity: Expressed only in lymphoid cell lines
genes like me logo Genes that share expressions with RAB33A: view

In Situ Assay Products

Orthologs for RAB33A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RAB33A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RAB33A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC784703 35
  • 95.5 (n)
  • 99.16 (a)
RAB33A 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RAB33A 35
  • 96.48 (n)
  • 100 (a)
RAB33A 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rab33a 35
  • 92.26 (n)
  • 98.31 (a)
Rab33a 16
Rab33a 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RAB33A 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rab33a 35
  • 93.11 (n)
  • 99.16 (a)
chicken
(Gallus gallus)
Aves RAB33A 35
  • 82.94 (n)
  • 88.26 (a)
RAB33A 36
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RAB33A 36
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rab33a 35
  • 65.89 (n)
  • 71.5 (a)
zebrafish
(Danio rerio)
Actinopterygii rab33a 35
  • 72.12 (n)
  • 78.76 (a)
rab33a 36
  • 76 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Rab9Fb 36
  • 32 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea rab-33 36
  • 36 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SEC4 36
  • 36 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8759 36
  • 55 (a)
OneToMany
Species with no ortholog for RAB33A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RAB33A Gene

ENSEMBL:
Gene Tree for RAB33A (if available)
TreeFam:
Gene Tree for RAB33A (if available)

Paralogs for RAB33A Gene

Paralogs for RAB33A Gene

genes like me logo Genes that share paralogs with RAB33A: view

Variants for RAB33A Gene

Sequence variations from dbSNP and Humsavar for RAB33A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs209545 -- 130,178,291(-) accca(C/G)gctgg intron-variant
rs209546 -- 130,178,241(-) tccta(G/T)gcgca intron-variant
rs209547 -- 130,175,873(-) TGGAT(C/T)ACAGA intron-variant
rs209548 -- 130,175,316(-) TATTG(C/T)CCTGT intron-variant
rs209549 -- 130,175,206(-) GGCTC(A/G)AGAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RAB33A Gene

Variant ID Type Subtype PubMed ID
nsv528290 CNV Gain 19592680

Relevant External Links for RAB33A Gene

HapMap Linkage Disequilibrium report
RAB33A
Locus Specific Mutation Databases (LSDB)
RAB33A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAB33A Gene

Disorders for RAB33A Gene

(1) University of Copenhagen DISEASES for RAB33A Gene

genes like me logo Genes that share disorders with RAB33A: view

No data available for UniProtKB/Swiss-Prot for RAB33A Gene

Publications for RAB33A Gene

  1. Molecular cloning of a cDNA encoding a novel small GTP-binding protein. (PMID: 7688322) Koda T. … Kakinuma M. (FEBS Lett. 1993) 2 3 4
  2. A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae. (PMID: 9512502) Zheng J.Y. … Kakinuma M. (J. Cell. Sci. 1998) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Ras-associated small GTPase 33A, a novel T cell factor, is down-regulated in patients with tuberculosis. (PMID: 16136464) Jacobsen M. … Kaufmann S.H. (J. Infect. Dis. 2005) 3

Products for RAB33A Gene

Sources for RAB33A Gene

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