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RAB31 Gene

protein-coding   GIFtS: 55
GCID: GC18P009701

RAB31, Member RAS Oncogene Family

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB31, Member RAS Oncogene Family1 2
Ras-Related Protein Rab-22B2 3
Rab22B2
Ras-Related Protein Rab-312
RAB22B3

External Ids:    HGNC: 97711   Entrez Gene: 110312   Ensembl: ENSG000001684617   OMIM: 6056945   UniProtKB: Q136363   

Export aliases for RAB31 gene to outside databases

Previous GC identifers: GC18P009925 GC18P009764 GC18P009699 GC18P009700


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB31 Gene:
Small GTP-binding proteins of the RAB family, such as RAB31, play essential roles in vesicle and granule targeting
(Bao et al., 2002 (PubMed 11784320)).(supplied by OMIM, Jul 2009)

GeneCards Summary for RAB31 Gene:
RAB31 (RAB31, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB31 include estrogen-receptor positive breast cancer, and type 1 diabetes. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RAB20.

UniProtKB/Swiss-Prot: RAB31_HUMAN, Q13636
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the
Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the
cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the
internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that
engulf pathogens, such as S.aureus and M.tuberculosis

Gene Wiki entry for RAB31 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the RAB31 gene promoter:
         SREBP-1c   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   NF-E2 p45   POU3F2   Arnt   SREBP-1b   GATA-2   SREBP-1a   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB31 promoter sequence
   Search Chromatin IP Primers for RAB31

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18p11.3   Ensembl cytogenetic band:  18p11.22   HGNC cytogenetic band: 18p11.22

RAB31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB31 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P009701:  view genomic region     (about GC identifiers)

Start:
9,708,162 bp from pter      End:
9,862,553 bp from pter
Size:
154,392 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAB31_HUMAN, Q13636 (See protein sequence)
Recommended Name: Ras-related protein Rab-31  
Size: 194 amino acids; 21569 Da
Subunit: Interacts with OCRL. Interacts with NGFR (By similarity). Interacts (in GDP-bound form) with RIN3 and
GAPVD1, which function as guanine exchange factors (GEF). Interacts (in GTP-bound form) with EEA1. Interacts with
EGFR
Sequence caution: Sequence=AAG09690.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAH01148.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for RAB31:
2FG5 (3D)    
Secondary accessions: B2RBT7 Q15770 Q9HC00

Explore the universe of human proteins at neXtProt for RAB31: NX_Q13636

Explore proteomics data for RAB31 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB31 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006859.2  
    ENSEMBL proteins: 
     ENSP00000461945   ENSP00000462164   ENSP00000464046   ENSP00000462561  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q13636

    ProtoNet protein and cluster: Q13636

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB31_HUMAN, Q13636
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RAB31 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB31_HUMAN, Q13636
    Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
    transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
    GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
    for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the
    Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the
    cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the
    internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that
    engulf pathogens, such as S.aureus and M.tuberculosis

         Genatlas biochemistry entry for RAB31:
    RAB31,RAS oncogene superfamily member,predominantly expressed in melanocytes

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS8863739
    GO:0005525GTP binding IDA17189207
    GO:0019003GDP binding IDA17189207
         
    RAB31 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for RAB31:
     Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa 

    Animal Models:
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB31

    miRNA
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    miRTarBase miRNAs that target RAB31:
    hsa-mir-140-3p (MIRT021663), hsa-mir-124-3p (MIRT022839), hsa-mir-196a-5p (MIRT026067)

    Block miRNA regulation of human, mouse, rat RAB31 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB31 (see all 23):
    hsa-miR-875-3p hsa-miR-218-2* hsa-miR-4263 hsa-miR-486-3p hsa-miR-29b-1* hsa-miR-1297 hsa-miR-2276 hsa-miR-29a*
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    Sino Biological Human cDNA Clone for RAB31
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB31

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB31


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB31_HUMAN, Q13636: Golgi apparatus, trans-Golgi network. Golgi apparatus, trans-Golgi network membrane;
    Lipid-anchor; Cytoplasmic side (Probable). Early endosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle,
    phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Rapidly recruited to phagosomes
    containing S.aureus or M.tuberculosis
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    cytosol3
    golgi apparatus3
    extracellular1
    lysosome1
    mitochondrion1
    nucleus1
    vacuole1

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005769early endosome IDA17189207
    GO:0005794Golgi apparatus IEA--

    RAB31 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB31 About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36
    2Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB31
        Epithelial Tight Junctions



    1 Kegg Pathway  (Kegg details for RAB31):
        Endocytosis


    RAB31 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB31
    Interactions:

        Search GeneGlobe Interaction Network for RAB31

    4 Interacting proteins for RAB31 (Q136362, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MPP3Q133682, 3MINT-64788 I2D: score=4 
    MAPK6Q166592, 3MINT-8261813 I2D: score=2 
    SLC2A4P146723I2D: score=1 
    OCRLQ019682MINT-8184810
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS8863739
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    RAB31 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB31



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAB31 gene: 
    NM_006868.3  

    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000578921 ENST00000578734 ENST00000581109 ENST00000583137 ENST00000435762
    ENST00000578737 ENST00000583921 ENST00000580361 ENST00000577796 ENST00000577371
    ENST00000580795 ENST00000577284
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate RAB31 (see all 23):
    hsa-miR-875-3p hsa-miR-218-2* hsa-miR-4263 hsa-miR-486-3p hsa-miR-29b-1* hsa-miR-1297 hsa-miR-2276 hsa-miR-29a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Primer
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    Selected AceView cDNA sequences (see all 554):

    BM698195 N59216 AL709685 BQ775467 AA809869 BQ006226 CR407659 AA045356 
    BU629214 AI581679 BF222931 AA436469 AI755005 CA307948 AA329239 Z41769 
    CA418051 BU629496 T34369 AI041898 AI802429 AA782299 BU542208 AI424636 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RAB31    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:                                      -     -                     
    SP2:        -                             -     -                     
    SP3:                                            -                     
    SP4:                                                                  


    ECgene alternative splicing isoforms for RAB31

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTCTATTC
    RAB31 Expression
    About this image


    RAB31 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 11) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 3 entries
             Human embryonic stem cells (family)
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Brain (Nervous System)
             Cerebral Cortex
    RAB31 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB31 Protein Expression

    UniProtKB/Swiss-Prot: RAB31_HUMAN, Q13636
    Tissue specificity: Highest expression in placenta and brain with lower levels in heart and lung. Not detected in
    liver, skeletal muscle, kidney or pancreas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RAB31 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab311 , 5 RAB31, member RAS oncogene family1, 5 88.38(n)1
    94.36(a)1
      17 (35.03 cM)5
    1065721  NM_133685.21  NP_598446.21 
     656517265 
    chicken
    (Gallus gallus)
    Aves RAB311 RAB31, member RAS oncogene family 83.15(n)
    93.41(a)
      430750  XM_428301.4  XP_428301.4 
    lizard
    (Anolis carolinensis)
    Reptilia RAB316
    RAB31, member RAS oncogene family
    89(a)
    1 ↔ 1
    GL343319.1(714910-742089)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rab311 RAB31, member RAS oncogene family 76.12(n)
    88.66(a)
      100101725  NM_001100241.1  NP_001093711.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5688001 ras-related protein Rab-31-like 72.34(n)
    80.93(a)
      568800  XM_692156.3  XP_697248.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VPS216
    YPT536
    Rab family GTPase required for endocytic transport...
    Rab family GTPase, similar to Ypt51p and Ypt52p an...
    41(a)
    37(a)
    many ↔ many
    many ↔ many
    XV(490196-490828) YOR089C
    XIV(449868-450530) YNL093W


    ENSEMBL Gene Tree for RAB31 (if available)
    TreeFam Gene Tree for RAB31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB31 gene
    RAB202  RAB5C2  ENSG000002672612  RAB5B2  RAB212  RAB5A2  RAB242  RAB22A2  
    RAB172  
    Selected SIMAP similar genes for RAB31 using alignment to 4 protein entries:     RAB31_HUMAN (see all proteins) (see all similar genes):
    RAB22A    RAB7A    DKFZp686J07132    RAB5B    RAB5C    RAB19
    RAB30    RAB39B    RAB6A    RAB17    RAB11B    RAB6B
    RAB11A    RAB3A    RAB3C    DKFZp313C1541    RAB37    RAB43

    RAB31 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RAB31
    PGOHUM00000249115


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB31 (see all 3616)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1854386771,2
    --9706264(+) TTTCAC/TGAGGC 1 -- us2k10--------
    rs1146643551,2
    F--9706340(+) ACAGAC/TTAGGA 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs753540361,2
    C,F--9706357(+) CTTTGT/CAAAGA 1 -- us2k11Minor allele frequency- C:0.02NA 120
    rs110814941,2
    C,F--9706436(+) AGGACA/GAATAG 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1890045391,2
    --9706469(+) GAAGGG/TCTGGA 1 -- us2k10--------
    rs1127132231,2
    C,F--9706491(+) TTTGGG/AAGAGC 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1164528151,2
    F--9706507(+) AACGAC/TGCAAG 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1158603541,2
    F--9706577(+) GTAAGG/AGAACA 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs1395688791,2
    C--9706582(+) GGAACA/TCAAGA 1 -- us2k10--------
    rs1434248301,2
    --9706584(+) AACACA/GAGAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RAB31 (9708162 - 9862553 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RAB31 (see all 22):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2661546CNV Deletion23128226
    esv2716775CNV Deletion23290073
    esv2716772CNV Deletion23290073
    nsv820745CNV Deletion20802225
    esv2716771CNV Deletion23290073
    esv2716774CNV Deletion23290073
    esv5001CNV Deletion18987735
    esv999723CNV Insertion20482838
    nsv507860CNV Insertion20534489
    nsv828177CNV Loss20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605694    OMIM disorders: --

    5 diseases for RAB31:    
    About MalaCards
    estrogen-receptor positive breast cancer    type 1 diabetes    tuberculosis    ovarian cancer
    breast cancer


    RAB31 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RAB31
    Human Genome Epidemiology (HuGE) Navigator: RAB31 (1 document)

    Export disorders for RAB31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB31 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with RAB31)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of two novel rab genes from human melanocytes. (PubMed id 8863739)1, 2, 3 Chen D.... Gahl W.A. (Gene 1996)
    2. Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31. (PubMed id 21586568)1, 2 Kajiho H.... Katada T. (J. Biol. Chem. 2011)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. (PubMed id 19725050)1, 2 Ng E.L.... Tang B.L. (J. Cell. Physiol. 2009)
    5. Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes. (PubMed id 17189207)1, 2 Lodhi I.J.... Saltiel A.R. (Cell Metab. 2007)
    6. Rab22B's role in trans-Golgi network membrane dynamics. (PubMed id 17678623)1, 2 Ng E.L.... Tang B.L. (Biochem. Biophys. Res. Commun. 2007)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Molecular cloning, bacterial expression and properties of Rab31 and Rab32. (PubMed id 11784320)1, 2 Bao X.... Haslam R.J. (Eur. J. Biochem. 2002)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 11031 HGNC: 9771 AceView: RAB31 Ensembl:ENSG00000168461 euGenes: HUgn11031
    ECgene: RAB31 Kegg: 11031 H-InvDB: RAB31

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RAB31 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB31 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for RAB31 gene:
    Search GeneIP for patents involving RAB31

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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