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RAB2B Gene

protein-coding   GIFtS: 54
GCID: GC14M021927

RAB2B, Member RAS Oncogene Family

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB2B, Member RAS Oncogene Family1 2
GTP-Binding Protein RAB2B2
RAS Family, Member RAB2B2
Ras-Related Protein Rab-2B2

External Ids:    HGNC: 202461   Entrez Gene: 849322   Ensembl: ENSG000001294727   OMIM: 6074665   UniProtKB: Q8WUD13   

Export aliases for RAB2B gene to outside databases

Previous GC identifers: GC14M015714 GC14M019917 GC14M020997 GC14M002046


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB2B Gene:
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that
contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated,
membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.(supplied by OMIM, Apr 2006)

GeneCards Summary for RAB2B Gene:
RAB2B (RAB2B, member RAS oncogene family) is a protein-coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAB19.

UniProtKB/Swiss-Prot: RAB2B_HUMAN, Q8WUD1
Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB2B gene promoter:
         Tal-1   CUTL1   AP-2gamma   E47   CREB   deltaCREB   AP-2beta   AP-2alpha   AP-2alphaA   Ik-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB2B promoter sequence
   Search Chromatin IP Primers for RAB2B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB2B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.1

RAB2B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB2B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M021927:  view genomic region     (about GC identifiers)

Start:
21,927,179 bp from pter      End:
21,945,132 bp from pter
Size:
17,954 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RAB2B_HUMAN, Q8WUD1 (See protein sequence)
Recommended Name: Ras-related protein Rab-2B  
Size: 216 amino acids; 24214 Da
1 PDB 3D structure from and Proteopedia for RAB2B:
2A5J (3D)    
Secondary accessions: B2RD03 D3DS24

Explore the universe of human proteins at neXtProt for RAB2B: NX_Q8WUD1

Explore proteomics data for RAB2B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys56
  • Modification sites at PhosphoSitePlus

  • See RAB2B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001156852.1  NP_116235.2  

    ENSEMBL proteins: 
     ENSP00000380869   ENSP00000405441  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q8WUD1

    ProtoNet protein and cluster: Q8WUD1

    UniProtKB/Swiss-Prot: RAB2B_HUMAN, Q8WUD1
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB2B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB2B_HUMAN, Q8WUD1
    Function: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005525GTP binding IEA--
         
    Find genes that share ontologies with RAB2B           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RAB2B

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    miRTarBase miRNAs that target RAB2B:
    hsa-mir-421 (MIRT039384)

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    Selected qRT-PCR Assays for microRNAs that regulate RAB2B (see all 16):
    hsa-miR-448 hsa-miR-640 hsa-miR-3190 hsa-miR-650 hsa-miR-583 hsa-miR-27b* hsa-miR-330-3p hsa-miR-3612
    SwitchGear 3'UTR luciferase reporter plasmidRAB2B 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB2B_HUMAN, Q8WUD1: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Endoplasmic reticulum membrane
    (Potential). Golgi apparatus membrane (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    endoplasmic reticulum3
    golgi apparatus3
    cytoskeleton1
    extracellular1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005789endoplasmic reticulum membrane IEA--

    Find genes that share ontologies with RAB2B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB2B About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB2B
        Epithelial Tight Junctions



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB2B
    Interactions:

        Search GeneGlobe Interaction Network for RAB2B

    2 Interacting proteins for RAB2B (Q8WUD13) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD4Q134853I2D: score=4 
    SMAD1Q157973I2D: score=3 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    Find genes that share ontologies with RAB2B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for RAB2B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB2B gene (2 alternative transcripts): 
    NM_001163380.1  NM_032846.3  

    Unigene Cluster for RAB2B:

    RAB2B, member RAS oncogene family
    Hs.22399  [show with all ESTs]
    Unigene Representative Sequence: NM_032846
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397762(uc010tls.2 uc001wax.3 uc010tlt.2 uc010ain.3)
    ENST00000417141 ENST00000461909 ENST00000475857 ENST00000485996
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    hsa-miR-448 hsa-miR-640 hsa-miR-3190 hsa-miR-650 hsa-miR-583 hsa-miR-27b* hsa-miR-330-3p hsa-miR-3612
    SwitchGear 3'UTR luciferase reporter plasmidRAB2B 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat RAB2B
      QuantiFast Probe-based Assays in human, mouse, rat RAB2B

    Additional mRNA sequence: 

    AF091029.1 AF468652.1 AK027730.1 AK296057.1 AK300599.1 AK307349.1 AK315354.1 BC020839.1 
    BC066366.1 BX647601.1 NR_028074.1 

    14 DOTS entries:

    DT.120763180  DT.415691  DT.99980592  DT.91732287  DT.100027172  DT.100027170  DT.100759573  DT.120763211 
    DT.120763131  DT.120763158  DT.120763205  DT.40132312  DT.100641376  DT.100759576 

    Selected AceView cDNA sequences (see all 134):

    AA738182 AF091029 BM556073 AA961980 BM263225 CD634472 BG034030 AA885791 
    F09894 AI003320 AK027730 BF735700 AW242144 AW778795 BX647601 BG699157 
    BX642144 AW191905 AA862442 BC020839 BG502390 BE935943 BG504257 BX642143 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RAB2B    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b
    SP1:                    -           -           -                                                   
    SP2:                    -           -           -     -                                             
    SP3:                    -           -                                                               
    SP4:                                -           -                                                   
    SP5:                    -                                                                           


    ECgene alternative splicing isoforms for RAB2B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB2B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATCAAAGCT
    RAB2B Expression
    About this image


    RAB2B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Eye (Sensory Organs)
             Retina
     
     Spinal Cord (Nervous System)
    RAB2B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB2B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.22399

    UniProtKB/Swiss-Prot: RAB2B_HUMAN, Q8WUD1
    Tissue specificity: Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and
    low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RAB2B gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab2b1 , 5 RAB2B, member RAS oncogene family1, 5 91.2(n)1
    94.91(a)1
      14 (26.87 cM)5
    763381  NM_172601.31  NP_766189.11 
     522617595 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    49(a)
    many ↔ many
    AADN03016787.1(596-1374)
    lizard
    (Anolis carolinensis)
    Reptilia RAB2B6
    RAB2B, member RAS oncogene family
    67(a)
    1 ↔ 1
    GL343466.1(460479-470285)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.27492 Xenopus laevis transcribed sequence with moderate similarity more 78.6(n)    CA790266.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab11al6
    RAB11a, member RAS oncogene family, like
    46(a)
    many ↔ many
    16(49892216-49908908) ENSDARG00000014340
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab26
    Rab-protein 2
    83(a)
    1 → many
    2R(2584227-2587441)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-1086
    Protein UNC-108 (unc-108) mRNA, complete cds
    86(a)
    1 → many
    I(3824947-3826514) WBGene00006833
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPT316
    YPT326
    Rab family GTPase, very similar to Ypt32p; involve...
    Rab family GTPase, very similar to Ypt31p; involve...
    41(a)
    39(a)
    many ↔ many
    many ↔ many
    V(214076-214747) YER031C
    VII(93792-94460) YGL210W
    rice
    (Oryza sativa)
    Liliopsida Os04g04701001 Os04g0470100 68.28(n)
    80.1(a)
      4336117  NM_001059583.1  NP_001053048.1 


    ENSEMBL Gene Tree for RAB2B (if available)
    TreeFam Gene Tree for RAB2B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB2B gene
    RAB192  RAB39A2  RAB2A2  RAB252  RAB432  RAB142  RAB4B2  RAB39B2  
    RAB11B2  RAB11A2  RAB422  RAB4A2  RAB302  RAB4B-EGLN22  
    Selected SIMAP similar genes for RAB2B using alignment to 4 protein entries:     RAB2B_HUMAN (see all proteins) (see all similar genes):
    DKFZp313C1541    RAB2A    RAB13    RAB8B    RAB14    RAB4B
    RAB4A    RAB8A    RAB19    RAB39B    DKFZp686J07132    RAB10
    RAB6A    RAB11A    RAB39A    RAB30    RAB15    RAB37

    Find genes that share paralogs with RAB2B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB2B (see all 328)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs593414141,2
    C--21926829(+) AAAAA-/AACAAAA 3 -- int10--------
    rs37900701,2
    C,F,A,H--21926847(+) AACAAA/CAAAAA 3 -- int19Minor allele frequency- C:0.07EA NS NA WA 1778
    rs10458421,2
    C,F,O,A,H--21927276(-) GTCCCA/GTTCTC 3 -- ut31 nc-transcript-variantese329Minor allele frequency- G:0.08MN NS EA NA WA CSA 2680
    rs761117521,2
    --21927339(+) TGAAGA/CAAAGG 3 -- ut31 nc-transcript-variant0--------
    rs1922100431,2
    --21927343(+) GCAAAA/GGCAAG 3 -- ut31 nc-transcript-variant0--------
    rs1472348301,2
    C--21927345(+) AAAGGC/GAAGTT 3 -- ut31 nc-transcript-variant0--------
    rs1487227641,2
    --21927372(+) ATATGC/GTCTGA 3 -- ut31 nc-transcript-variant0--------
    rs49813721,2
    C,F,A,H--21927638(+) ATGAGT/CAGCAC 3 -- ut31 nc-transcript-variantese325Minor allele frequency- C:0.20NA NS EA WA CSA 2482
    rs1414559141,2
    C--21927821(+) ACATAG/TGAATA 3 -- ut31 nc-transcript-variant0--------
    rs10458121,2
    C,F,H--21928338(-) GCCTCG/AGAATT 3 -- ut31 nc-transcript-variant30Minor allele frequency- A:0.19NA NS EA WA CSA EU 3505

    HapMap Linkage Disequilibrium report for RAB2B (21927179 - 21945132 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RAB2B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422459CNV Duplication17116639

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB2B
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB2B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607466    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RAB2B:
    Oculocerebrorenal syndrome

    Find genes that share disorders with RAB2B           About GenesLikeMe


    Export disorders for RAB2B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB2B gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with RAB2B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of a novel human Rab (Rab2B) gene. (PubMed id 12376746)1, 2, 3, 9 Ni X.... Mao Y. (J. Hum. Genet. 2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    5. PKCI/ promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. (PubMed id 22304920)1 Lau E....Ronai Z.A. (Cell 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Rab27a and Rab27b control different steps of the exosome secretion pathway. (PubMed id 19966785)1 Ostrowski M....Thery C. (Nat. Cell Biol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84932 HGNC: 20246 AceView: RAB2B Ensembl:ENSG00000129472 euGenes: HUgn84932
    ECgene: RAB2B H-InvDB: RAB2B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RAB2B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB2B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB2B gene:
    Search GeneIP for patents involving RAB2B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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