Aliases for RAB2A Gene
External Ids for RAB2A Gene
Previous HGNC Symbols for RAB2A Gene
Previous GeneCards Identifiers for RAB2A Gene
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for RAB2A Gene
RAB2A (RAB2A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB2A include Sezary's Disease and Lipoblastoma. Among its related pathways are Mitotic Prophase and RAB geranylgeranylation. GO annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB2B.
UniProtKB/Swiss-Prot for RAB2A Gene
Required for protein transport from the endoplasmic reticulum to the Golgi complex.