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RAB28 Gene

protein-coding   GIFtS: 55
GCID: GC04M013369

RAB28, Member RAS Oncogene Family

  See RAB28-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB28, Member RAS Oncogene Family1 2
CORD182 5
Ras-Related Protein Rab-282

External Ids:    HGNC: 97681   Entrez Gene: 93642   Ensembl: ENSG000001578697   OMIM: 6129945   UniProtKB: P511573   

Export aliases for RAB28 gene to outside databases

Previous GC identifers: GC04M013212 GC04U900009 GC04M013057 GC04M013120 GC04M013045 GC04M012707


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB28 Gene:
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved
in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants.
Pseudogenes of this gene are found on chromosomes 9 and X. (provided by RefSeq, Apr 2009)

GeneCards Summary for RAB28 Gene:
RAB28 (RAB28, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB28 include cone-rod dystrophy 18, and ectodermal dysplasia 4, hair/nail type. GO annotations related to this gene include GDP binding and GTP binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_006316.17  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB28 gene promoter:
         POU2F2C   Oct-B1   POU2F1   oct-B3   oct-B2   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB28 promoter sequence
   Search Chromatin IP Primers for RAB28

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB28


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p15.33   Ensembl cytogenetic band:  4p15.33   HGNC cytogenetic band: 4p16.1

RAB28 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB28 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M013369:  view genomic region     (about GC identifiers)

Start:
13,362,978 bp from pter      End:
13,485,989 bp from pter
Size:
123,012 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAB28_HUMAN, P51157 (See protein sequence)
Recommended Name: Ras-related protein Rab-28 precursor  
Size: 221 amino acids; 24841 Da
2 PDB 3D structures from and Proteopedia for RAB28:
2HXS (3D)        3E5H (3D)    
Secondary accessions: G8JLC5 Q8IYR8 Q8NI05
Alternative splicing: 3 isoforms:  P51157-1   P51157-2   P51157-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RAB28: NX_P51157

Explore proteomics data for RAB28 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB28 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001017979.1  NP_001153073.1  NP_004240.2  

    ENSEMBL proteins: 
     ENSP00000424899   ENSP00000424043   ENSP00000328551   ENSP00000288723   ENSP00000422816  
     ENSP00000424091   ENSP00000340079  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    3 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry P51157

    ProtoNet protein and cluster: P51157

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB28_HUMAN, P51157
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB28           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS8647132
    GO:0005525GTP binding IDA19026641
    GO:0019003GDP binding IDA19026641
         
    Find genes that share ontologies with RAB28           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for RAB28:
     Cell cycle / mitosis defect  Decreased nuclei size in G2M  Decreased p24 protein expressi  Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB28
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    miRTarBase miRNAs that target RAB28:
    hsa-mir-375 (MIRT019946), hsa-mir-197-3p (MIRT004181)

    Block miRNA regulation of human, mouse, rat RAB28 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RAB28:
    hsa-miR-498 hsa-miR-338-5p hsa-miR-147
    SwitchGear 3'UTR luciferase reporter plasmidRAB28 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB28_HUMAN, P51157: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Cytoplasm, cytoskeleton, cilium
    basal body. Note=Expressed in the basal body and ciliary rootlet of the photoreceptors (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    cytoskeleton1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----

    Find genes that share ontologies with RAB28           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB28 About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB28
        Epithelial Tight Junctions



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB28
    Interactions:

        Search GeneGlobe Interaction Network for RAB28

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB28 (ENSP000003285514) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD4ENSP000003415514STRING: ENSP00000341551
    EXOC2ENSP000002304494STRING: ENSP00000230449
    EXOC4ENSP000002538614STRING: ENSP00000253861
    EXOC7ENSP000003341004STRING: ENSP00000334100
    EXOC6ENSP000002607624STRING: ENSP00000260762
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    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process TAS8647132
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    Find genes that share ontologies with RAB28           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB28



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB28 gene (3 alternative transcripts): 
    NM_001017979.2  NM_001159601.1  NM_004249.3  

    Unigene Cluster for RAB28:

    RAB28, member RAS oncogene family
    Hs.656060  [show with all ESTs]
    Unigene Representative Sequence: BX537681
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000511649 ENST00000508274 ENST00000330852(uc003gmu.2 uc003gmv.2)
    ENST00000288723(uc003gmt.2) ENST00000504644 ENST00000510528 ENST00000338176(uc011bwz.1)

    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate RAB28:
    hsa-miR-498 hsa-miR-338-5p hsa-miR-147
    SwitchGear 3'UTR luciferase reporter plasmidRAB28 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RAB28
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB28
    Primer
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    OriGene qPCR primer pairs and template standards for RAB28
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB28
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB28
      QuantiTect SYBR Green Assays in human, mouse, rat RAB28
      QuantiFast Probe-based Assays in human, mouse, rat RAB28

    Additional mRNA sequence: 

    AF498955.1 BC018067.1 BC035054.2 BX537681.1 X94703.1 

    12 DOTS entries:

    DT.95074907  DT.217999  DT.91923892  DT.217998  DT.95309902  DT.100008711  DT.121251983  DT.91747764 
    DT.95181071  DT.121252012  DT.40274367  DT.95309905 

    Selected AceView cDNA sequences (see all 111):

    BU630749 AI084521 BU742941 BM801937 R25903 W72006 CR612152 Z41536 
    AK027027 AA744838 Z45911 AI689194 CF456155 N50159 BM920172 AI215961 
    BC018067 CR592237 AI015919 N49476 CR616293 CR597076 N46403 CR621879 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RAB28    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:                                            -     -               
    SP2:                    -     -                 -     -               
    SP3:                                            -                     
    SP4:                                                                  


    ECgene alternative splicing isoforms for RAB28

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB28 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCGGACTCTG
    RAB28 Expression
    About this image


    RAB28 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Limb (Muscoskeletal System)
             Autopod
     
     Thyroid (Endocrine System)
     
     Esophagus (Gastrointestinal Tract)
    RAB28 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB28 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656060

    UniProtKB/Swiss-Prot: RAB28_HUMAN, P51157
    Tissue specificity: Isoform S is detected in most tissues investigated: cortex, liver, kidney, skeletal muscle,
    adipose tissue, testis, urothelium, lung, bone marrow and retinal pigment epithelium (RPE). Isoform L 2 is widely
    and abundantly expressed all tissues. Isoform 3 is highly expressed in heart, lung, bone marrow, retina, brain,
    and RPE

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB28 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab281 , 5 RAB28, member RAS oncogene family1, 5 92.01(n)1
    95.48(a)1
      5 (22.58 cM)5
    1009721  NM_027295.21  NP_081571.11 
     416249765 
    chicken
    (Gallus gallus)
    Aves RAB281 RAB28, member RAS oncogene family 83.56(n)
    86.88(a)
      422839  NM_001277923.1  NP_001264852.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB286
    RAB28, member RAS oncogene family
    80(a)
    1 ↔ 1
    GL343366.1(445316-481504)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.151682 Transcribed sequence with moderate similarity to protein more 81.52(n)    BX713531.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufe49e062 wufe49e06 78.48(n)   326923  BC045389.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rab-281 rab-28 50.84(n)
    48.4(a)
      189429  NM_069208.1  NP_501609.1 


    ENSEMBL Gene Tree for RAB28 (if available)
    TreeFam Gene Tree for RAB28 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB28 gene
    Selected SIMAP similar genes for RAB28 using alignment to 5 protein entries:     RAB28_HUMAN (see all proteins) (see all similar genes):
    RAB7A    RAB40C    RAB7L1    RHOF    RAB38    MRAS
    RHOD    ARL8B    RAB19    RAB43    RAB35    RAB13
    RAB1A    DKFZp547A0616    RAB31    RAP2A    RAB12    RAB11A

    Find genes that share paralogs with RAB28           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for RAB28 (see all 6)
    PGOHUM00000236087 PGOHUM00000236106 PGOHUM00000236146 PGOHUM00000236152 PGOHUM00000236489


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB28 (see all 2390)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs99980291,2
    C,F--13368915(+) GAGACA/CAGCAC 3 -- ds50014Minor allele frequency- C:0.05CSA WA NA 242
    rs1885489511,2
    --13369163(+) CAGCTA/GATGTG 3 -- ds50010--------
    rs99983191,2
    C,F--13369219(+) CAACAA/GAATAA 3 -- ds50014Minor allele frequency- G:0.06CSA WA NA 242
    rs1421626661,2
    --13369268(+) ACAGAA/TTCACT 3 -- ds50010--------
    rs1931138831,2
    --13369290(+) CAAATA/GCACAC 3 -- ds50010--------
    rs100316231,2
    C,F,A,H--13369324(+) GATGTC/TTGAAA 3 -- ds50018Minor allele frequency- T:0.04NS EA CSA WA NA 660
    rs100317101,2
    C,F--13369426(+) TCATTC/TTCGGG 3 -- ut311Minor allele frequency- T:0.04WA 118
    rs154121,2
    C,F--13369429(+) TTCTCA/G/TGGAGT 6 -- ut31 ese31MN 184
    rs1397616471,2
    C--13369437(+) AGTACA/TCTTAT 3 -- ut310--------
    rs1830911161,2
    --13369558(+) AAAAAC/TACAAT 3 -- ut310--------

    HapMap Linkage Disequilibrium report for RAB28 (13362978 - 13485989 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RAB28:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2665157CNV Deletion23128226
    nsv829866CNV Loss17160897
    esv25888CNV Loss19812545

    Human Gene Mutation Database (HGMD): RAB28
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB28
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB28

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612994   
    OMIM disorders: 615374  
    UniProtKB/Swiss-Prot: RAB28_HUMAN, P51157
  • Cone-rod dystrophy 18 (CORD18) [MIM:615374]: A form of cone-rod dystrophy, an inherited retinal dystrophy
    characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and
    initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and
    sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs
    earlier than in retinitis pigmentosa. Note=The disease is caused by mutations affecting the gene represented in
    this entry

  • 3 diseases for RAB28:    
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    cone-rod dystrophy 18    ectodermal dysplasia 4, hair/nail type    cone-rod dystrophy 2


    Find genes that share disorders with RAB28           About GenesLikeMe

    Genetic Association Database (GAD): RAB28
    Human Genome Epidemiology (HuGE) Navigator: RAB28 (2 documents)

    Export disorders for RAB28 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB28 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with RAB28)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Alternative mRNA splicing of the novel GTPase Rab28 generates isoforms with different C-termini. (PubMed id 8647132)1, 2, 3, 9 Brauers A.... Joost H.-G. (Eur. J. Biochem. 1996)
    2. Mutations in RAB28, encoding a farnesylated small GTPase, are associated with autosomal-recessive cone-rod dystrophy. (PubMed id 23746546)1, 2 Roosing S....den Hollander A.I. (Am. J. Hum. Genet. 2013)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Large nucleotide-dependent conformational change in Rab28. (PubMed id 19026641)1, 2 Lee S.H.... Dominguez R. (FEBS Lett. 2008)
    5. Towards complete sets of farnesylated and geranylgeranylated proteins. (PubMed id 17411337)1, 2 Maurer-Stroh S....Eisenhaber F. (PLoS Comput. Biol. 2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9364 HGNC: 9768 AceView: RAB28 Ensembl:ENSG00000157869 euGenes: HUgn9364
    ECgene: RAB28 H-InvDB: RAB28

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB28 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB28 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB28 gene:
    Search GeneIP for patents involving RAB28

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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