Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RAB26 Gene

protein-coding   GIFtS: 52
GCID: GC16P002190

RAB26, Member RAS Oncogene Family

  Search for RAB26
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
RAB26, Member RAS Oncogene Family1 2
V461332
Ras-Related Oncogene Protein2
Ras-Related Protein Rab-262

External Ids:    HGNC: 142591   Entrez Gene: 258372   Ensembl: ENSG000001679647   OMIM: 6054555   UniProtKB: Q9ULW53   

Export aliases for RAB26 gene to outside databases

Previous GC identifers: GC16P002215 GC16P002138 GC16P002198 GC16P002124


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for RAB26 Gene:
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking.
The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis,
endocytosis, and recycling (summary by Seki et al., 2000 (PubMed 11043516)).(supplied by OMIM, Nov 2010)

GeneCards Summary for RAB26 Gene:
RAB26 (RAB26, member RAS oncogene family) is a protein-coding gene. GO annotations related to this gene include GMP binding and GTP binding. An important paralog of this gene is RAB10.

UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to
the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the
stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland

Gene Wiki entry for RAB26 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB26 gene promoter:
         CREB   AP-1   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): RAB26 promoter sequence
   Search Chromatin IP Primers for RAB26

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB26


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

RAB26 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB26 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P002190:  view genomic region     (about GC identifiers)

Start:
2,190,804 bp from pter      End:
2,204,166 bp from pter
Size:
13,363 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5 (See protein sequence)
Recommended Name: Ras-related protein Rab-26  
Size: 256 amino acids; 27900 Da
Subunit: Interacts with RIMS1 (By similarity). Interacts with ADRA2B
Sequence caution: Sequence=BAA84707.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for RAB26:
2G6B (3D)    
Secondary accessions: Q3L6K5 Q6NXS7

Explore the universe of human proteins at neXtProt for RAB26: NX_Q9ULW5

Explore proteomics data for RAB26 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB26 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055168.2  
    ENSEMBL proteins: 
     ENSP00000454373   ENSP00000441580   ENSP00000210187   ENSP00000455675  

    RAB26 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for RAB26
    OriGene Protein Over-expression Lysate for RAB26
    OriGene MassSpec for RAB26
    OriGene Custom Protein Services for RAB26
    GenScript Custom Purified and Recombinant Proteins Services for RAB26
    Novus Biologicals RAB26 Proteins
    Novus Biologicals RAB26 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RAB26

     
    Search eBioscience for Proteins for RAB26 

    RAB26 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for RAB26
    OriGene Custom Antibody Services for RAB26
    Novus Biologicals RAB26 Antibodies
    Abcam antibodies for RAB26
    Cloud-Clone Corp. Antibodies for RAB26
    ThermoFisher Antibodies for RAB26
    LSBio Antibodies in human, mouse, rat for RAB26

    RAB26 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RAB26
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RAB26
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RAB26
    Cloud-Clone Corp. CLIAs for RAB26
    Search eBioscience for ELISAs for RAB26 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9ULW5

    ProtoNet protein and cluster: Q9ULW5

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB26           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB26_HUMAN, Q9ULW5
    Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
    transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
    GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
    for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to
    the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the
    stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005515protein binding ----
    GO:0005525GTP binding ISS--
    GO:0019002GMP binding IMP--
         
    Find genes that share ontologies with RAB26           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB26
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB26

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RAB26
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RAB26

    miRNA
    Products:
        
    miRTarBase miRNAs that target RAB26:
    hsa-mir-421 (MIRT039448), hsa-mir-335-5p (MIRT017292)

    Block miRNA regulation of human, mouse, rat RAB26 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RAB26:
    hsa-miR-922 hsa-miR-3119 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidRAB26 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RAB26
    Predesigned siRNA for gene silencing in human, mouse, rat RAB26

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RAB26

    Clone
    Products:
         
    OriGene clones in human, mouse for RAB26 (see all 6)
    OriGene ORF clones in mouse, rat for RAB26
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAB26 (NM_014353)
    Sino Biological Human cDNA Clone for RAB26
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB26
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB26
    Addgene plasmids for RAB26 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RAB26
    Browse ESI BIO Cell Lines and PureStem Progenitors for RAB26 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB26


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    RAB26_HUMAN, Q9ULW5: Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, secretory
    vesicle membrane; Lipid-anchor; Cytoplasmic side (Probable). Note=Not localized at the plasma membrane (By
    similarity). Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    plasma membrane4
    cytosol3
    mitochondrion3
    nucleus1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IDA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0016020membrane ----

    Find genes that share ontologies with RAB26           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for RAB26 About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB26
        Epithelial Tight Junctions



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB26
    Interactions:

        GeneGlobe Interaction Network for RAB26

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for RAB26 (Q9ULW53 ENSP000002101874) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GCH1P307933, ENSP000003788904I2D: score=2 STRING: ENSP00000378890
    RPH3ALQ9UNE23, ENSP000003192104I2D: score=1 STRING: ENSP00000319210
    RIMS1Q86UR53, ENSP000002648394I2D: score=3 STRING: ENSP00000264839
    RPH3AQ9Y2J03, ENSP000004132544I2D: score=1 STRING: ENSP00000413254
    CDC42EP1ENSP000002490144STRING: ENSP00000249014
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    Find genes that share ontologies with RAB26           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB26



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RAB26 gene: 
    NM_014353.4  

    Unigene Cluster for RAB26:

    RAB26, member RAS oncogene family
    Hs.3797  [show with all ESTs]
    Unigene Representative Sequence: AK308560
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000565592 ENST00000541451 ENST00000564426(uc010bsf.3) ENST00000562735
    ENST00000210187(uc002cou.3) ENST00000561600 ENST00000567145 ENST00000566724

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RAB26 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate RAB26:
    hsa-miR-922 hsa-miR-3119 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidRAB26 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RAB26
    Predesigned siRNA for gene silencing in human, mouse, rat RAB26
    Clone
    Products:
         
    OriGene clones in human, mouse for RAB26 (see all 6)
    OriGene ORF clones in mouse, rat for RAB26
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAB26 (NM_014353)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB26
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB26
    Addgene plasmids for RAB26 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB26
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB26
      QuantiTect SYBR Green Assays in human, mouse, rat RAB26
      QuantiFast Probe-based Assays in human, mouse, rat RAB26

    Additional mRNA sequence: 

    AB027137.1 AF498952.1 AK308560.1 AK309666.1 AK314110.1 AY646153.1 BC007681.2 BC066913.1 

    7 DOTS entries:

    DT.107062  DT.95263381  DT.95263382  DT.100778284  DT.100035948  DT.100690238  DT.120688259 

    Selected AceView cDNA sequences (see all 84):

    CR598645 BQ688147 NM_014353 CK826126 AF498952 AW206417 CA943353 AI871963 
    BU076677 AB027137 BQ687186 BE222260 BX464097 BU076619 CB154847 BM544365 
    CB242472 CA945231 AV683344 AV697216 AV696539 BX091565 AW088377 BI916873 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RAB26    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c
    SP1:                                      -                                                               
    SP2:                                      -                                                               
    SP3:                                                                                                      
    SP4:              -                       -                                                               
    SP5:              -                                                                                       


    ECgene alternative splicing isoforms for RAB26

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RAB26 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCAGGCAGC
    RAB26 Expression
    About this image

    RAB26 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB26 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.3797

    UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5
    Tissue specificity: Predominantly expressed in brain

        Custom PCR Arrays for RAB26
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB26
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB26
    QuantiTect SYBR Green Assays in human, mouse, rat RAB26
    QuantiFast Probe-based Assays in human, mouse, rat RAB26
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB26

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for RAB26 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab261 , 5 RAB26, member RAS oncogene family1, 5 84.58(n)1
    87.45(a)1
      17 (12.40 cM)5
    3287781  NM_177375.11  NP_796349.11 
     245272415 
    chicken
    (Gallus gallus)
    Aves RAB261 RAB26, member RAS oncogene family 79.15(n)
    84.93(a)
      416554  XM_414855.4  XP_414855.4 
    lizard
    (Anolis carolinensis)
    Reptilia RAB266
    RAB26, member RAS oncogene family
    83(a)
    1 ↔ 1
    AAWZ02037120(339-15275)
    zebrafish
    (Danio rerio)
    Actinopterygii rab156
    RAB15, member RAS oncogene family
    42(a)
    many ↔ many
    20(28808811-28826907) ENSDARG00000026484
    fruit fly
    (Drosophila melanogaster)
    Insecta CG76053
    Rab261
    RAB small monomeric GTPase3
    Rab261
    63(a)3
    67.01(n)1
    64.47(a)1
      78C73
    403591  NM_001275222.11  NP_001262151.11 
    worm
    (Caenorhabditis elegans)
    Secernentea rab-376
    Protein RAB-37, isoform b
    49(a)
    1 → many
    X(4227857-4235846) WBGene00004285


    ENSEMBL Gene Tree for RAB26 (if available)
    TreeFam Gene Tree for RAB26 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RAB26 gene
    RAB102  RAB3B2  RAB8A2  RAB3D2  RAB372  RAB8B2  RAB3A2  RAB1B2  
    RAB122  RAB1A2  RAB132  RAB3C2  
    Selected SIMAP similar genes for RAB26 using alignment to 4 protein entries:     RAB26_HUMAN (see all proteins) (see all similar genes):
    RAB37    RAB8B    rab1b    RAB13    RAB39B    RAB8A
    RAB15    RAB10    DKFZp686J07132    RAB14    RAB19    RAB3A
    RAB43    RAB3C    RAB30    DKFZp313C1541    RAB39A    RAB3B

    Find genes that share paralogs with RAB26           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for RAB26 (see all 37)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1165639151,2
    C,F--2203106(+) GCTGTC/TCCCGC 1 -- int11Minor allele frequency- T:0.02WA 118
    rs1876544761,2
    C--2203120(+) GCCACC/TACCTG 1 -- int10--------
    rs1920910781,2
    C--2203176(+) ACCAGC/TGCCAA 2 S syn10--------
    rs2008848561,2
    --2203194(+) CTCAAC/TGTGGA 2 N syn10--------
    rs1834986881,2
    C--2203235(+) CCTGCC/TAGTCA 1 -- int10--------
    rs2004784301,2
    --2203238(+) GCCAGC/TCACCA 1 -- int10--------
    rs1891364391,2
    C--2203249(+) GGACTC/TCCCCA 1 -- int10--------
    rs1995696311,2
    C--2203302(+) CCCTTC/GTCACC 1 -- int10--------
    rs1129251141,2
    C--2203316(+) ACTCCA/G/TCAGGG 1 -- int11CSA 2
    rs1494021891,2
    C,F--2203334(+) GCAGCG/ACTCCA 2 /H /R mis11Minor allele frequency- A:0.00NA 4502

    HapMap Linkage Disequilibrium report for RAB26 (2190804 - 2204166 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RAB26 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422427CNV Duplication17116639
    dgv2562n71CNV Loss21882294
    dgv2545n71CNV Loss21882294
    nsv905131CNV Loss21882294
    dgv2546n71CNV Loss21882294
    dgv2564n71CNV Loss21882294
    dgv2540n71CNV Loss21882294
    nsv457349CNV Loss19166990
    nsv471072CNV Loss18288195
    dgv2549n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB26
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB26

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 605455    OMIM disorders: --


    Find genes that share disorders with RAB26           About GenesLikeMe

    Genetic Association Database (GAD): RAB26
    Human Genome Epidemiology (HuGE) Navigator: RAB26 (3 documents)

    Export disorders for RAB26 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RAB26 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with RAB26)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP- binding protein on chromosome 16p13.3 region. (PubMed id 11043516)1, 2, 3 Seki N....Saito T. (J. Hum. Genet. 2000)
    2. Rab26 modulates the cell surface transport of alpha2-adrenergic receptors from the Golgi. (PubMed id 23105096)1, 2 Li C.... Wu G. (J. Biol. Chem. 2012)
    3. RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation. (PubMed id 20038531)1, 2 Tian X.... Mills J.C. (Mol. Cell. Biol. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (Nature 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    10. A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions. (PubMed id 16696853)1 Swick L. and Kapatos G. (J. Neurochem. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 25837 HGNC: 14259 AceView: RAB26 Ensembl:ENSG00000167964 euGenes: HUgn25837
    ECgene: RAB26 H-InvDB: RAB26

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RAB26 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB26 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RAB26 gene:
    Search GeneIP for patents involving RAB26

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for RAB26   OriGene RNAi products in human, mouse, rat for RAB26  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for RAB26  
     OriGene MassSpec something-or-other for RAB26   OriGene clones in human, mouse for RAB26  
     OriGene qSTAR qPCR primer pairs in human, mouse for RAB26   OriGene Purified Protein for RAB26  
     OriGene ORF clones in mouse, rat for RAB26   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RAB26   OriGene Custom Protein Services for RAB26  

     
     
     Block miRNA regulation of human, mouse, rat RAB26 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RAB26
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB26 Predesigned siRNA for gene silencing in human, mouse, rat RAB26
     QuantiFast Probe-based Assays in human, mouse, rat RAB26 QuantiTect SYBR Green Assays in human, mouse, rat RAB26
     Custom PCR Arrays for RAB26 Search Chromatin IP Primers for RAB26
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB26  GeneGlobe Interaction Network for RAB26
     Regulatory tfbs in RAB26 promoter
     GenScript Custom Purified and Recombinant Proteins Services for RAB26 GenScript cDNA clones with any tag delivered in your preferred vector for RAB26
     GenScript Custom Assay Services for RAB26 GenScript Custom overexpressing Cell Line Services for RAB26
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RAB26
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for RAB26
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RAB26 antibodies
     RAB26 proteins
     RAB26 lysates
     Antibodies for RAB26
     See all of Abcam's Antibodies, Kits and Proteins for RAB26
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RAB26
     Antibodies for RAB26
     ELISAs for RAB26
     CLIAs for RAB26



     Browse ESI BIO Cell Lines and PureStem Progenitors for RAB26
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB26
     SwitchGear 3'UTR luciferase reporter plasmids for RAB26
     SwitchGear Promoter luciferase reporter plasmids for RAB26
     ThermoFisher Antibodies for RAB26
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB26
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB26
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RAB26
     LSBio Antibodies in human, mouse, rat for RAB26
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Addgene plasmids for RAB26
      Search eBioscience for proteins for RAB26
      Search eBioscience for elisas for RAB26
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RAB26 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4