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Aliases & Descriptions for RAB26
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| | | Descriptions |
|---|
| RAB26, member RAS oncogene family 2 | | Ras-related oncogene protein 2 |
|
| | Search outside databases for aliases for RAB26 genePrevious GC identifer: GC16P002215 |
Summaries for RAB26(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5Function: Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland (By similarity)Gene Wiki entry for RAB26 |
Genomic Location for RAB26
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the RAB26 gene 
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3RAB26 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P002138:
(about GC identifiers)
Start:
|
2,138,646 bp from pter |
End:
|
2,144,142 bp from pter |
Size:
|
5,497 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000016.8 NT_037887.4
| Proteins for RAB26
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5 (See
protein sequence)Recommended Name: Ras-related protein Rab-26 Size: 256 amino acids; 27900 Da
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity)
PDB structures from and Proteopedia :2G6B (3D)
 
Secondary accessions: Q6NXS7REFSEQ proteins: NP_055168.2
ENSEMBL proteins: ENSP00000210187
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: RAB26 
3 Gene Ontology (GO) cellular component terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- | | GO:0005886 | plasma membrane |
IEA | -- | | GO:0031226 | intrinsic to plasma membrane |
ISS | -- | About this table
Antibodies for RAB26: Assays for RAB26: | Protein
Domains/ Families for RAB26(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q9ULW5
ProtoNet protein and cluster: Q9ULW5 1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature
UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5Similarity: Belongs to the small GTPase superfamily. Rab family | Gene Function for RAB26
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014353
Applied Biosystems Silencer® siRNAs for RAB26
Sigma-Aldrich siRNA for RAB26  Sigma-Aldrich shRNA for RAB26  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014353                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_014353                                  untagged cDNA clone in CMV expression vector: NM_014353 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_014353
UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5Function: Participates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland (By similarity)3 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for RAB26
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for RAB26 
2 Interacting proteins for RAB26 (ENSP000002101873 Q9ULW51) via UniProtKB, MINT, and/or STRINGAbout this table
5 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
IEA | -- | | GO:0008150 | biological_process |
ND | -- | | GO:0015031 | protein transport |
IEA | -- | | GO:0017157 | regulation of exocytosis |
ISS | -- | | GO:0035272 | exocrine system development |
ISS | -- | About this table
|
Drugs & Compounds for RAB26(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|  |
Enzo Life Sciences drugs & compounds for RAB26 |
Browse Tocris compounds for RAB26
|
Transcripts for RAB26(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014353
Sigma-Aldrich siRNA for RAB26  Sigma-Aldrich shRNA for RAB26  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_014353 REFSEQ mRNAs for RAB26 gene: NM_014353.4
Applied Biosystems TaqMan ® Gene Expression Assays: NM_014353               OriGene GFP tagged cDNA clone in CMV expression vector: NM_014353                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_014353                                  untagged cDNA clone in CMV expression vector: NM_014353  Additional cDNA sequence: AB027137.1 AF498952.1 AK308560.1 AK309666.1 AK314110.1 AY646153.1 BC007681.2 BC066913.1 CR598645.1 7 DOTS entries: DT.107062 DT.100778284 DT.95263381 DT.95263382 DT.100035948 DT.100690238 DT.120688259 24/84 AceView cDNA sequences (see all 84
):CK826126 AW206417 CA943353 BE222260 AI871963 BQ688147 AF498952 BU076677 AB027137 CR598645 NM_014353 BQ687186 AW088377 BC007681 AV692701 AV697216 T08521 AV683344 BU076619 AL568072 BX464097 BM853818 BU196326 BM689146
highest scoring ESTs for RAB26:AI690165 AA573872 AA969796 AB027137 AF498952 AI348380 AI871963 AW088377 AW205643 AW206417 Unigene Cluster for RAB26: RAB26, member RAS oncogene family Hs.3797 [show with all ESTs]Unigene Representative Sequence: AK308560
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for RAB26
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for RAB26
1 Ensembl transcript including schematic representation: ENST00000210187
|
Expression for RAB26
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| RAB26 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for RAB26
1 / 2 / 3 5 probe-sets matching RAB26 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: CTCAGGCAGC
SOURCE GeneReport for Unigene cluster: Hs.3797 UniProtKB/Swiss-Prot: RAB26_HUMAN, Q9ULW5Tissue specificity: Predominantly expressed in brain |
Orthologs for RAB26
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for RAB26 gene from 5/8 species (see all 8
)
About this table Species with no ortholog for RAB26
ENSEMBL Gene Tree for RAB26 | Paralogs for RAB26(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for RAB26 gene
- RAB27A2 RAB27B2 RAB372
|
SNPs/Variants for RAB26(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for RAB26 (up to first 250kb)
|
Disorders & Mutations for RAB26
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 605455
|
Medical News for RAB26(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for RAB26 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 8 PubMed articles for RAB26 gene:- cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP- binding protein on chromosome 16p13.3 region. (PubMed id 11043516)2, 3, 4 Seki N....Saito T. (2000)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)3, 4 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions. (PubMed id 16696853)3 Swick L. and Kapatos G. (2006)
- Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. (PubMed id 12578829)3 Fukuda M. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland. (PubMed id 10857477)3 Yoshie S....Shimomura H. (2000)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)3 Bonaldo M.F....Soares M.B. (1996)
|
Search for RAB26
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RAB26
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing RAB26
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAB26(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for RAB26(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for RAB26:

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Incremental update: 13 Oct 2009
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