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RAB24 Gene

protein-coding   GIFtS: 53
GCID: GC05M176728

RAB24, Member RAS Oncogene Family

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB24, Member RAS Oncogene Family1 2
Ras-Related Protein Rab-242

External Ids:    HGNC: 97651   Entrez Gene: 539172   Ensembl: ENSG000001692287   OMIM: 6124155   UniProtKB: Q969Q53   

Export aliases for RAB24 gene to outside databases

Previous GC identifers: GC05M177101 GC05M177570 GC05M176663 GC05M176709 GC05M176660 GC05M171648


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB24 Gene:
RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein
trafficking (Olkkonen et al., 1993 (PubMed 8126105)).(supplied by OMIM, Aug 2009)

GeneCards Summary for RAB24 Gene:
RAB24 (RAB24, member RAS oncogene family) is a protein-coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAB20.

UniProtKB/Swiss-Prot: RAB24_HUMAN, Q969Q5
Function: May be involved in autophagy-related processes (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NC_018916.2  NT_023133.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB24 gene promoter:
         AML1a   RelA   NF-kappaB   Gfi-1   HEN1   ARP-1   STAT3   IRF-7A   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB24 promoter sequence
   Search Chromatin IP Primers for RAB24

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

RAB24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB24 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M176728:  view genomic region     (about GC identifiers)

Start:
176,728,199 bp from pter      End:
176,730,745 bp from pter
Size:
2,547 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RAB24_HUMAN, Q969Q5 (See protein sequence)
Recommended Name: Ras-related protein Rab-24  
Size: 203 amino acids; 23124 Da
Subunit: Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including
ARHGDIA and ARHGDIB. Interacts with ZFYVE20
Miscellaneous: The unusual Ser-67, instead of a conserved Gln in other family members, is the cause of low GTPase
activity. As a result, the predominant nucleotide associated with the protein is GTP (By similarity)
Secondary accessions: Q7Z4Z7

Explore the universe of human proteins at neXtProt for RAB24: NX_Q969Q5

Explore proteomics data for RAB24 at MOPED

Post-translational modifications: 

  • Isoprenylation is inefficient compared to other Rab family members1
  • Ubiquitination2 at Lys104
  • Modification sites at PhosphoSitePlus

  • See RAB24 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001026847.1  NP_570137.2  

    ENSEMBL proteins: 
     ENSP00000377235   ENSP00000304376   ENSP00000302085   ENSP00000421442  

    RAB24 Human Recombinant Protein Products:

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    Novus Biologicals RAB24 Proteins
    Novus Biologicals RAB24 Lysates
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    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for RAB24
    Cloud-Clone Corp. Proteins for RAB24

     
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    antibodies-online proteins for RAB24 (6 products) 

     
    antibodies-online peptides for RAB24

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    antibodies-online antibodies for RAB24 (52 products) 

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    antibodies-online kits for RAB24 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q969Q5

    ProtoNet protein and cluster: Q969Q5

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB24_HUMAN, Q969Q5
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB24           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB24_HUMAN, Q969Q5
    Function: May be involved in autophagy-related processes (By similarity)
    Induction: By extensive retinoic acid treatment, in Ntera-2 teratoma cell line induced to differentiate into
    post-mitotic neurons (NTN2) (at protein level)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005515protein binding IPI16034420
    GO:0005525GTP binding IEA--
         
    Find genes that share ontologies with RAB24           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Rab24 (no phenotypes)

    Find genes that share phenotypes with RAB24           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Rab24tm1(KOMP)Wtsi for RAB24

       genOway: Develop your customized and physiologically relevant rodent model for RAB24

    miRNA
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    Block miRNA regulation of human, mouse, rat RAB24 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB24 (see all 11):
    hsa-miR-615-5p hsa-miR-185* hsa-miR-148b hsa-miR-3166 hsa-miR-128 hsa-miR-3681* hsa-miR-152 hsa-miR-661
    SwitchGear 3'UTR luciferase reporter plasmidRAB24 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB24

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): RAB24 (NM_130781)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB24

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB24


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB24_HUMAN, Q969Q5: Cytoplasm, cytosol. Membrane; Lipid-anchor (By similarity). Note=Only about 20-25% is
    recovered in the particulate fraction
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    mitochondrion2
    vacuole2
    endosome1
    extracellular1
    golgi apparatus1
    lysosome1
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion IEA--
    GO:0005776autophagic vacuole IEA--
    GO:0005829cytosol IEA--
    GO:0016020membrane IEA--

    Find genes that share ontologies with RAB24           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB24 About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB24
        Epithelial Tight Junctions


        Pathway & Disease-focused RT2 Profiler PCR Array including RAB24: 
              Autophagy in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for RAB24

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB24 (Q969Q53 ENSP000003043764) via UniProtKB, MINT, STRING, and/or I2D (see all 220)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0006914autophagy IEA--
    GO:0007165signal transduction ----

    Find genes that share ontologies with RAB24           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB24



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB24 gene (2 alternative transcripts): 
    NM_001031677.3  NM_130781.3  

    Unigene Cluster for RAB24:

    RAB24, member RAS oncogene family
    Hs.16258  [show with all ESTs]
    Unigene Representative Sequence: BF569067
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000478234(uc003mfv.3 uc003mfw.3) ENST00000393611 ENST00000495458
    ENST00000303251 ENST00000303270 ENST00000471466 ENST00000393610 ENST00000504395
    ENST00000512758
    miRNA
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    Block miRNA regulation of human, mouse, rat RAB24 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB24 (see all 11):
    hsa-miR-615-5p hsa-miR-185* hsa-miR-148b hsa-miR-3166 hsa-miR-128 hsa-miR-3681* hsa-miR-152 hsa-miR-661
    SwitchGear 3'UTR luciferase reporter plasmidRAB24 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB24
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RAB24 (NM_130781)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB24
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RAB24
    OriGene qSTAR qPCR primer pairs in human, mouse for RAB24
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RAB24
      QuantiTect SYBR Green Assays in human, mouse, rat RAB24
      QuantiFast Probe-based Assays in human, mouse, rat RAB24

    Additional mRNA sequence: 

    AF087904.1 AK308155.1 AL833898.1 BC010006.2 BC015534.1 BC021263.2 BT007268.1 

    22 DOTS entries:

    DT.100821934  DT.97855774  DT.120865378  DT.100821945  DT.95229548  DT.97804529  DT.100821940  DT.100821942 
    DT.65288081  DT.120865267  DT.120865308  DT.100821938  DT.100821944  DT.120865356  DT.100821946  DT.120865302 
    DT.120865358  DT.91756282  DT.95213853  DT.95229549  DT.111589  DT.120865263 

    Selected AceView cDNA sequences (see all 709):

    CR624761 AL043472 BF917860 BM830144 BF917592 BI829480 CA943130 BQ653169 
    CR606209 AW183470 CR620709 BU620484 CB154865 BM475000 BU155030 CD722684 
    BQ944189 CA312389 BQ447313 AA745918 BM728518 CR613352 T29958 CA748464 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for RAB24    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b
    SP1:                                            -               
    SP2:                    -                                       
    SP3:                                                            
    SP4:                                            -               
    SP5:                                                            


    ECgene alternative splicing isoforms for RAB24

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGAGGGATA
    RAB24 Expression
    About this image

    RAB24 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB24 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.16258
        Pathway & Disease-focused RT2 Profiler PCR Array including RAB24: 
              Autophagy in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB24 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab241 , 5 RAB24, member RAS oncogene family1, 5 89(n)1
    98.52(a)1
      13 (29.80 cM)5
    193361  NM_009000.31  NP_033026.11 
     553192235 
    chicken
    (Gallus gallus)
    Aves RAB241 RAB24, member RAS oncogene family 79.8(n)
    82.27(a)
      427627  NM_001277713.1  NP_001264642.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB246
    RAB24, member RAS oncogene family
    86(a)
    1 ↔ 1
    2(145433196-145438477)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.99372 Xenopus laevis transcribed sequence with moderate similarity more 78.44(n)    BJ617214.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab241 RAB24, member RAS oncogene family 69.47(n)
    76.24(a)
      574423  NM_001029970.1  NP_001025141.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta chrw6
    chrowded
    25(a)
    1 → many
    2R(19407362-19411096)


    ENSEMBL Gene Tree for RAB24 (if available)
    TreeFam Gene Tree for RAB24 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB24 gene
    RAB202  RAB5C2  ENSG000002672612  RAB312  RAB5B2  RAB212  RAB5A2  RAB22A2  
    RAB172  
    Selected SIMAP similar genes for RAB24 using alignment to 5 protein entries:     RAB24_HUMAN (see all proteins) (see all similar genes):
    rab1b    RAB5C    RAB21    RAB5B    RAB17    RAB6A
    RAB6A'    RAB6B    RAB14    RAB31    RAB4B    RAB35
    RAB38    RAB5A    RAB11A    RAB7A    RAB4A    RAB19

    Find genes that share paralogs with RAB24           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB24 (see all 22)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1889406941,2
    --176727790(+) TGATTC/TCTCAG 2 -- ds50010--------
    rs771547331,2
    C--176727962(+) GTAGTC/TACCTT 2 -- ds50010--------
    rs766731881,2
    C,F--176728228(+) TATTTC/GGAAGC 2 -- ut311Minor allele frequency- G:0.06WA 118
    rs1401175651,2
    --176728292(+) ACAGCC/TCCAGT 2 -- ut310--------
    rs1392623961,2
    C--176728319(+) TGGGG-/AAAAAA 2 -- ut310--------
    rs1503678971,2
    --176728328(+) AAGTCC/TTGTTT 2 -- ut310--------
    rs1156242041,2
    C,F--176728332(+) CTTGTT/CTTCCA 2 -- ut311Minor allele frequency- C:0.02WA 118
    rs284191821,2
    C,F--176728400(+) CCCAGA/GAAGAA 2 -- ut3112Minor allele frequency- G:0.25NA WA CSA EA 376
    rs1810893411,2
    --176728457(+) TGTGAG/TGCACA 2 -- ut310--------
    rs11282871,2
    C,F,H--176728458(-) CTGTGA/CATCAC 2 -- ut31 ese325Minor allele frequency- C:0.27MN NS EA NA WA CSA 2534

    HapMap Linkage Disequilibrium report for RAB24 (176728199 - 176730745 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RAB24:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv883159CNV Loss21882294
    dgv6379n71CNV Loss21882294
    nsv428132CNV Gain18775914
    dgv1878e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing RAB24
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB24

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612415    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RAB24:
    Q fever

    Find genes that share disorders with RAB24           About GenesLikeMe

    Genetic Association Database (GAD): RAB24
    Human Genome Epidemiology (HuGE) Navigator: RAB24 (1 document)

    Export disorders for RAB24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB24 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with RAB24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Structural basis of family-wide Rab GTPase recognition by rabenosyn- 5. (PubMed id 16034420)1, 2 Eathiraj S.... Lambright D.G. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Rab24 is an atypical member of the Rab GTPase family. Deficient GTPase activity, GDP dissociation inhibitor interaction, and prenylation of Rab24 expressed in cultured cells. (PubMed id 10660536)1, 2 Erdman R.A.... Maltese W.A. (J. Biol. Chem. 2000)
    5. Rab24 is required for normal cell division. (PubMed id 23387408)1 Militello R.D....Colombo M.I. (Traffic 2013)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. (PubMed id 20360680)1 Schlager M.A....Hoogenraad C.C. (EMBO J. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 53917 HGNC: 9765 AceView: LMAN2andMXD3andRAB24 Ensembl:ENSG00000169228 euGenes: HUgn53917
    ECgene: RAB24 H-InvDB: RAB24

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB24 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB24 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB24 gene:
    Search GeneIP for patents involving RAB24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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