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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB23 Gene

protein-coding   GIFtS: 57
GCID: GC06M057100

RAB23, member RAS oncogene family

 Explore 9 diseases affiliated with
RAB23 via our new
 Human Malady Compendium 
Biological research products
for RAB23
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
RAB23, Member RAS Oncogene Family1 2
HSPC1372
RAB Family Small GTP Binding Protein RAB 232
Ras-Related Protein Rab-232

External Ids:    HGNC: 142631   Entrez Gene: 517152   Ensembl: ENSG000001122107   OMIM: 6061445   UniProtKB: Q9ULC33   

Export aliases for RAB23 gene to outside databases

Previous GC identifers: GC06M057055 GC06M057161 GC06M056887


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RAB23:
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small
GTPase mediated signal transduction and intracellular protein transportation. Alternative splicing occurs at this
locus and two transcript variants encoding the same protein have been identified. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: RAB23_HUMAN, Q9ULC3
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for
vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby
inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3
proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole
assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that
then merge with lysosomes

Gene Wiki entry for RAB23


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB23 gene promoter:
         STAT1   FOXO4   STAT1beta   STAT5A   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB23 promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB23

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p11   Ensembl cytogenetic band:  6p11.2   HGNC cytogenetic band: 6p12.1

RAB23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB23 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M057100:  view genomic region     (about GC identifiers)

Start:
57,053,581 bp from pter      End:
57,087,078 bp from pter
Size:
33,498 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RAB23_HUMAN, Q9ULC3 (See protein sequence)
Recommended Name: Ras-related protein Rab-23 precursor  
Size: 237 amino acids; 26659 Da
Subunit: Interacts with SUFU
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity). Cell membrane. Cytoplasm.
Cytoplasmic vesicle, autophagosome. Endosome membrane (By similarity). Cytoplasmic vesicle, phagosome. Cytoplasmic
vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Recruited to phagosomes containing
S.aureus or M.tuberculosis
Secondary accessions: B2R9I5 Q68DJ6 Q8NI06 Q9P023

Explore the universe of human proteins at neXtProt for RAB23: NX_Q9ULC3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9ULC3

  • RAB23 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_057361.3  NP_899050.1  

    ENSEMBL proteins: 
     ENSP00000417610   ENSP00000320413  

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    Novus Biologicals RAB23 Proteins
    Novus Biologicals RAB23 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for RAB23
    Uscn Proteins for RAB23

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005776autophagic vacuole IDA--
    GO:0005886plasma membrane IEA--
    GO:0010008endosome membrane IEA--
    GO:0030670phagocytic vesicle membrane IEA--


    RAB23 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RAB23 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type

    Graphical View of Domain Structure for InterPro Entry Q9ULC3

    ProtoNet protein and cluster: Q9ULC3

    1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB23_HUMAN, Q9ULC3
    Similarity: Belongs to the small GTPase superfamily. Rab family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RAB23_HUMAN, Q9ULC3
    Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
    transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
    GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for
    vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby
    inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3
    proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole
    assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that
    then merge with lysosomes

    miRNA
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    miRTarBase miRNAs that target RAB23:
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    OriGene 3'-UTR Clone (see all 2): RAB23
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RAB23
    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB23 (see all 20):
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    SwitchGear 3'UTR luciferase reporter plasmidRAB23 3' UTR sequence
    Inhib. RNA
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    OriGene siRNA: RAB23
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB23

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity IDA--
    GO:0005525GTP binding IEA--


    RAB23 for ontologies           About GeneDecksing


    Animal Models:
         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Rab23):
     embryogenesis  integument  limbs/digits/tail  mortality/aging  nervous system 
     skeleton  vision/eye 

    RAB23 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Hedgehog signaling events mediated by Gli proteins
    Hedgehog signaling events mediated by Gli proteins1.00
    2Hedgehog Signaling Pathway
    Hedgehog Signaling Pathway1.00
    3Basal cell carcinoma
    Hedgehog signaling pathway0.41
    4Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for RAB23
        Epithelial Tight Junctions

    2 BioSystems Pathways for RAB23 
        Hedgehog Signaling Pathway
    Hedgehog signaling events mediated by Gli proteins


    1         Kegg Pathway  (Kegg details for RAB23):
        Hedgehog signaling pathway


    RAB23 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RAB23

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/8 Interacting proteins for RAB23 (Q9ULC33 ENSP000003204134) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREB3O438893I2D: score=1 
    GLI2ENSP000003545864STRING: ENSP00000354586
    RAB3IPENSP000003680864STRING: ENSP00000368086
    SMOENSP000002493734STRING: ENSP00000249373
    OPTNENSP000002630364STRING: ENSP00000263036
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000045autophagic vacuole assembly IMP--
    GO:0006184GTP catabolic process IDA--
    GO:0006968cellular defense response IMP--
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--


    RAB23 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RAB23
    Search CenterWatch for drugs/clinical trials and news about RAB23 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB23 gene (2 alternative transcripts): 
    NM_016277.3  NM_183227.1  

    Unigene Cluster for RAB23:

    RAB23, member RAS oncogene family
    Hs.555016  [show with all ESTs]
    Unigene Representative Sequence: NM_016277
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000344445(uc010kad.3) ENST00000468148 ENST00000317483(uc003pds.3 uc003pdt.3 uc010kac.3)


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    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB23 (see all 20):
    hsa-miR-30c hsa-miR-3128 hsa-miR-429 hsa-miR-1271 hsa-miR-25 hsa-miR-30d hsa-miR-30a hsa-miR-649
    SwitchGear 3'UTR luciferase reporter plasmidRAB23 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAB23
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAB23

    Additional cDNA sequence: 

    AB025427.1 AB034244.1 AF161486.1 AF498951.1 AK311123.1 AK313796.1 AY585189.1 BC015021.1 
    CR749371.1 

    8 DOTS entries:

    DT.100686704  DT.40217313  DT.92421553  DT.100784040  DT.121390121  DT.447994  DT.121389888  DT.97809189 

    24/156 AceView cDNA sequences (see all 156):

    BQ024315 BF939214 BU625890 AW268477 AI721188 AI093515 BU628543 AY585189 
    AB025427 BU618863 AW069459 AA694297 AI669457 AL047421 AI684848 CB147015 
    AI537589 AA134569 BI086338 AA150152 AI670097 AI628941 AI078466 AA705004 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for RAB23 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:                          -     -     -                                                               
    SP2:                                                                                                      
    SP3:                          -     -     -     -     -     -                                             
    SP4:              -     -     -     -     -                                                               
    SP5:                                      -                                                               


    ECgene alternative splicing isoforms for RAB23

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGTCATTTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RAB23 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB23

    SOURCE GeneReport for Unigene cluster: Hs.555016
        SABiosciences Expression via Pathway-Focused PCR Arrays including RAB23: 
              Hedgehog Signaling Pathway in human mouse rat
              Primary Cilia in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RAB23 gene from 5/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves RAB231 RAB23, member RAS oncogene family 80.87(n)
    88.61(a)
      421879  NM_001110060.1  NP_001103530.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB236
    --
    90(a)
    1 ↔ 1
    1(162975857-162993797)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.152952 Transcribed sequence with moderate similarity to protein more 79.19(n)    CF589439.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570348492   -- 99.82(n)    57034849 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG21083
    Rab231
    RAB small monomeric GTPase3
    CG2108-PA1
    59(a)3
    59.94(n)1
    63.85(a)1
      83B93
    407011  NM_141317.21  NP_649574.11 


    ENSEMBL Gene Tree for RAB23 (if available)
    TreeFam Gene Tree for RAB23 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB23 gene
    RAB27A2  RAB3A2  RAB3B2  RAB27B2  RAB3D2  RAB3C2  
    18/82 SIMAP similar genes for RAB23 using alignment to 1 protein entry:     RAB23_HUMAN(see all similar genes):
    RAB7A    DKFZp686J07132    RAB3C    RAB7B    RAB13    RAB11A
    RAB3A    RAB3B    RAB30    RAB19    RAB3D    RANP1
    RAB11B    RAB12    RAB5B    RAB9A    RAB8B    RAB17

    RAB23 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/487 NCBI SNPs in RAB23 are shown (see all 487    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1219081711,2
    C,pathogenic57642122(-) AAAGTT/AAAGAT 4 /* /L stg11Minor allele frequency- A:0.00NA 4532
    rs119692001,2
    C,F,H,--56887610(+) GCCAGA/GTCATT 2 -- ds50015Minor allele frequency- G:0.01NS EA CSA 422
    rs113981,2
    C,F,A,H,--56888004(-) TTGTCA/GCTTGG 2 -- ut31 ese326Minor allele frequency- N:0.00MN NA NS EA CSA WA 3039
    rs1826621,2
    C,F,A,H,--56888065(+) TGATTC/TTGTAT 2 -- ut31 ese313Minor allele frequency- T:0.03EA NA MN NS 924
    rs773534671,2
    --56888328(+) CACACT/GTCACA 2 -- ut311Minor allele frequency- G:0.01NA 120
    rs168883781,2
    C,F,H,--56888505(+) ATCTAC/TGCTGT 2 -- ut31 ese38Minor allele frequency- T:0.04NA NS WA 1050
    rs14115781,2
    C,F,O,H,--56888900(+) AGATTC/GAATAC 2 -- ut31 ese310Minor allele frequency- G:0.13MN NS EA NA CSA WA 846
    rs28402621,2
    H--56889172(+) AAGCAC/ATGCAG 2 -- ut314Minor allele frequency- A:0.00NS EA 420
    rs45590911,2
    H--56889223(+) GCAAAG/TTCTGC 2 -- ut31 ese34Minor allele frequency- T:0.00NS EA 420
    rs778686411,2
    C,--56890804(+) TCCAGC/TAGTCC 2 -- int13Minor allele frequency- T:0.08NA EA 242

    HapMap Linkage Disequilibrium report for RAB23 (57053581 - 57087078 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RAB23: --
    Human Gene Mutation Database (HGMD): RAB23

    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing RAB23:
    Gastric Cancer
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RAB23 for disorders           About GeneDecksing

    OMIM gene information: 606144   
    OMIM disorders: 201000  
    UniProtKB/Swiss-Prot: RAB23_HUMAN, Q9ULC3
  • Defects in RAB23 are the cause of Carpenter syndrome 1 (CRPT1) [MIM:201000]. A syndrome characterized by
  • craniosynostosis, polysyndactyly, obesity, and cardiac defects

    9 diseases for RAB23:    About MalaCards
    beare-stevenson cutis gyrata syndrome    pallister-hall syndrome    carpenter syndrome    craniosynostosis
    hepatocellular carcinoma    gastric cancer    obesity    carcinoma
    neuronitis

    3 diseases from the University of Copenhagen DISEASES database for RAB23:
    Beare-Stevenson cutis gyrata syndrome     Craniosynostosis     Dextrocardia

    Export disorders for RAB23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB23 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with RAB23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Rab23 negatively regulates Gli1 transcriptional factor in a Su(Fu)-dependent manner. (PubMed id 22365972)1, 2 Chi S....Xie J. (2012)
    2. The small GTPases Rab9A and Rab23 function at distinct steps in autophagy during group A Streptococcus infection. (PubMed id 22452336)1, 2 Nozawa T.... Nakagawa I. (2012)
    3. Carpenter syndrome: extended RAB23 mutation spectrum and analysis of nonsense-mediated mRNA decay. (PubMed id 21412941)1, 2 Jenkins D.... Wilkie A.O. (2011)
    4. RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesity. (PubMed id 17503333)1, 2 Jenkins D.... Wilkie A.O.M. (2007)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (PubMed id 21255211)2 Seto S.... Koide Y. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51715 HGNC: 14263 AceView: RAB23 Ensembl:ENSG00000112210 euGenes: HUgn51715
    ECgene: RAB23 Kegg: 51715 H-InvDB: RAB23

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB23 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB23 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB23 gene:
    Search GeneIP for patents involving RAB23

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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