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RAB22A Gene

protein-coding   GIFtS: 56
GCID: GC20P056884

RAB22A, Member RAS Oncogene Family

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB22A, Member RAS Oncogene Family1 2
GTP-Binding Protein RAB22A2
rab-222
Ras-Related Protein Rab-22A2
RAB223
Rab-223

External Ids:    HGNC: 97641   Entrez Gene: 574032   Ensembl: ENSG000001242097   OMIM: 6129665   UniProtKB: Q9UL263   

Export aliases for RAB22A gene to outside databases

Previous GC identifers: GC20P056613 GC20P057523 GC20P057570 GC20P056318 GC20P053667


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB22A Gene:
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded
protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and
interaction between endosomal compartments. (provided by RefSeq, Jul 2008)

GeneCards Summary for RAB22A Gene:
RAB22A (RAB22A, member RAS oncogene family) is a protein-coding gene. Diseases associated with RAB22A include insulin resistance, and tuberculosis. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RAB20.

UniProtKB/Swiss-Prot: RB22A_HUMAN, Q9UL26
Function: Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early
endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite
outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a
GDP-bound inactive form

Gene Wiki entry for RAB22A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NT_011362.11  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB22A gene promoter:
         SRF   AP-1   SRF (504 AA)   Ik-3   c-Ets-1   CREB   deltaCREB   FOXO1a   Pax-4a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): RAB22A promoter sequence
   Search Chromatin IP Primers for RAB22A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB22A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q13.32   Ensembl cytogenetic band:  20q13.32   HGNC cytogenetic band: 20q13

RAB22A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB22A gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P056884:  view genomic region     (about GC identifiers)

Start:
56,884,752 bp from pter      End:
56,942,563 bp from pter
Size:
57,812 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RB22A_HUMAN, Q9UL26 (See protein sequence)
Recommended Name: Ras-related protein Rab-22A  
Size: 194 amino acids; 21855 Da
Subunit: Interacts directly with ZFYVE20 (By similarity). Binds EEA1 (By similarity). Interacts (in its GTP-bound
form) with RABGEF1. Interacts (in its GTP-bound form) with RINL
Secondary accessions: B3KR86 E1P605 Q8TF12 Q9H4E6

Explore the universe of human proteins at neXtProt for RAB22A: NX_Q9UL26

Explore proteomics data for RAB22A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB22A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065724.1  
    ENSEMBL proteins: 
     ENSP00000244040  

    RAB22A Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9UL26

    ProtoNet protein and cluster: Q9UL26

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RB22A_HUMAN, Q9UL26
    Similarity: Belongs to the small GTPase superfamily. Rab family


    RAB22A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RB22A_HUMAN, Q9UL26
    Function: Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early
    endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite
    outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a
    GDP-bound inactive form

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS11870209
    GO:0005515protein binding IPI11870209
    GO:0005525GTP binding IEA--
    GO:0019003GDP binding IDA--
         
    RAB22A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB22A:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB22A
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    miRNA
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    miRTarBase miRNAs that target RAB22A:
    hsa-mir-30b-5p (MIRT046136), hsa-mir-211-5p (MIRT006465), hsa-mir-204-5p (MIRT005840), hsa-mir-128-3p (MIRT045852), hsa-mir-21-5p (MIRT030782)

    Block miRNA regulation of human, mouse, rat RAB22A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB22A (see all 160):
    hsa-miR-124* hsa-miR-579 hsa-miR-100* hsa-miR-520f hsa-miR-106a hsa-miR-3653 hsa-miR-1273d hsa-miR-208b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB22A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RB22A_HUMAN, Q9UL26: Endosome membrane; Lipid-anchor (By similarity). Cell membrane; Lipid-anchor (By
    similarity). Early endosome. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome.
    Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Note=Recruited to
    phagosomes containing S.aureus or M.tuberculosis
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    plasma membrane5
    cytosol3
    cytoskeleton2
    nucleus2
    vacuole2
    extracellular1
    golgi apparatus1
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IEA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005769early endosome IDA11870209

    RAB22A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB22A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36
    2Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB22A
        Epithelial Tight Junctions



    1 Kegg Pathway  (Kegg details for RAB22A):
        Endocytosis


    RAB22A for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB22A
    Interactions:

        GeneGlobe Interaction Network for RAB22A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB22A (Q9UL261, 2, 3 ENSP000002440404) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APPL1Q9UKG12, 3, ENSP000002882664MINT-5204082 I2D: score=1 STRING: ENSP00000288266
    EEA1Q150751, 3, ENSP000003179554EBI-399456,EBI-298113 I2D: score=3 STRING: ENSP00000317955
    APPL2Q8NEU82, 3, ENSP000002585304MINT-67006 I2D: score=5 STRING: ENSP00000258530
    RAB7AP511493, ENSP000002650624I2D: score=1 STRING: ENSP00000265062
    RABAC1Q9UI143, ENSP000002220084I2D: score=1 STRING: ENSP00000222008
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006897endocytosis IDA11870209
    GO:0006913nucleocytoplasmic transport ----
    GO:0007032endosome organization IEP11870209

    RAB22A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB22A (RB22A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RAB22A gene: 
    NM_020673.2  

    Unigene Cluster for RAB22A:

    RAB22A, member RAS oncogene family
    Hs.529044  [show with all ESTs]
    Unigene Representative Sequence: NM_020673
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000244040(uc002xyz.3) ENST00000488949
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate RAB22A (see all 160):
    hsa-miR-124* hsa-miR-579 hsa-miR-100* hsa-miR-520f hsa-miR-106a hsa-miR-3653 hsa-miR-1273d hsa-miR-208b
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      QuantiTect SYBR Green Assays in human, mouse, rat RAB22A
      QuantiFast Probe-based Assays in human, mouse, rat RAB22A

    Additional mRNA sequence: 

    AF091034.2 AJ276210.1 AK054767.1 AK091180.1 BC007036.1 BC015710.1 BC016864.1 BC042545.1 
    BC063457.1 BT007046.1 

    7 DOTS entries:

    DT.87078920  DT.444701  DT.92438895  DT.100834909  DT.120800784  DT.75111983  DT.40202127 

    Selected AceView cDNA sequences (see all 294):

    F08512 BF431654 BF063561 AI151183 AA554316 AI914465 AW467145 AA978305 
    CD672277 BC063457 NM_020673 BG117302 AA195101 AA679966 BU538226 AA758198 
    AI308231 AA457216 BU146346 AJ276210 BQ433929 BM767269 CK429657 AA398963 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB22A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RAB22A Expression
    About this image

    RAB22A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB22A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.529044
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RAB22A gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab22a1 , 5 RAB22A, member RAS oncogene family1, 5 90.03(n)1
    97.42(a)1
      2 (97.26 cM)5
    193341  NM_024436.31  NP_077756.21 
     1736597605 
    chicken
    (Gallus gallus)
    Aves RAB22A1 RAB22A, member RAS oncogene family 86.08(n)
    96.39(a)
      419318  NM_001030867.1  NP_001026038.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB22A6
    RAB22A, member RAS oncogene family
    96(a)
    1 ↔ 1
    GL343217.1(125755-147118)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.153612 Danio rerio clone RK113A4H10 RAB22A, member RAS oncogene more 75.06(n)    AY398404.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TEM1(YML064C)4 GTP-binding protein of the ras superfamily involved more   --   13(145876-145139) 854938  NP_013647.1 


    ENSEMBL Gene Tree for RAB22A (if available)
    TreeFam Gene Tree for RAB22A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB22A gene
    RAB202  RAB5C2  ENSG000002672612  RAB312  RAB5B2  RAB212  RAB5A2  RAB242  
    RAB172  
    Selected SIMAP similar genes for RAB22A using alignment to 1 protein entry:     RB22A_HUMAN(see all similar genes):
    RAB31    RAB5C    RAB5B    RAB30    DKFZp686J07132    RAB5A
    RAB11B    RAB3A    RAB39B    RAB11A    RAB43    RAB8B
    RAB17    RAB12    RAB39A    RAB6B    RAB19    RAB21

    RAB22A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB22A (see all 1179)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs353750061,2
    C--53682865(+) AAAAA-/AACTGTA 1 -- int12Minor allele frequency- AA:0.25NA 4
    rs766121671,2
    C,F--56886666(+) GTTCTA/GTGGAT 1 -- int11Minor allele frequency- G:0.05NA 120
    rs739158051,2
    C--56886695(+) ATATGT/CTTTTG 1 -- int12Minor allele frequency- C:0.04WA 120
    rs1486596091,2
    --56886703(+) TTGACA/GCTATA 1 -- int10--------
    rs1887744001,2
    --56886866(+) AAAAAA/TCTATG 1 -- int10--------
    rs1421799311,2
    --56886916(+) GCAGAC/TCATTC 1 -- int10--------
    rs1815574411,2
    --56887104(+) CCTCCA/CGGGTT 1 -- int10--------
    rs124803831,2
    C,H--56887156(+) ATGGGC/TGCCCA 1 -- int12Minor allele frequency- T:0.32NA EA 122
    rs60704221,2
    C,H--56887239(+) ctcctG/Aacctc 1 -- int15Minor allele frequency- A:0.00NA WA 10
    rs713354731,2
    C,F--56887367(+) TGGAGC/TGCAGT 1 -- int12Minor allele frequency- T:0.50NA 4

    HapMap Linkage Disequilibrium report for RAB22A (56884752 - 56942563 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for RAB22A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv828760CNV Loss20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB22A
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB22A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612966    OMIM disorders: --

    3 diseases for RAB22A:    About MalaCards
    insulin resistance    tuberculosis    type 1 diabetes


    RAB22A for disorders           About GeneDecksing

    Genetic Association Database (GAD): RAB22A

    Export disorders for RAB22A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB22A gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with RAB22A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Rab22a regulates the sorting of transferrin to recycling endosomes. (PubMed id 16537905)1, 2 Magadan J.G.... Mayorga L.S. (Mol. Cell. Biol. 2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    5. Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells. (PubMed id 10887961)1, 2 Opdam F.J.M....Fransen J.A.M. (Eur. J. Cell Biol. 2000)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. (PubMed id 21255211)2 Seto S.... Koide Y. (Traffic 2011)
    8. Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22. (PubMed id 21419809)2 Woller B.... Herbst R. (Biochim. Biophys. Acta 2011)
    9. Rab22 controls NGF signaling and neurite outgrowth in PC12 cells. (PubMed id 21849477)2 Wang L.... Li G. (Mol. Biol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57403 HGNC: 9764 AceView: RAB22A Ensembl:ENSG00000124209 euGenes: HUgn57403
    ECgene: RAB22A Kegg: 57403 H-InvDB: RAB22A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB22A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB22A Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB22A gene:
    Search GeneIP for patents involving RAB22A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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