Aliases for RAB22A Gene
External Ids for RAB22A Gene
Previous GeneCards Identifiers for RAB22A Gene
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]
GeneCards Summary for RAB22A Gene
RAB22A (RAB22A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Endocytosis and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB5C.
UniProtKB/Swiss-Prot for RAB22A Gene
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.