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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB1B Gene

protein-coding   GIFtS: 60
GCID: GC11P066036

RAB1B, member RAS oncogene family

 Explore 6 diseases affiliated with
RAB1B via our new
 Human Malady Compendium 
Biological research products
for RAB1B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
RAB1B, Member RAS Oncogene Family1 2
Ras-Related Protein Rab-1B2
Small GTP-Binding Protein2

External Ids:    HGNC: 183701   Entrez Gene: 818762   Ensembl: ENSG000001749037   OMIM: 6125655   UniProtKB: Q9H0U43   

Export aliases for RAB1B gene to outside databases

Previous GC identifers: GC11P068570 GC11P067717 GC11P066285 GC11P065811 GC11P065792 GC11P065777 GC11P062361


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RAB1B:
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic
surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for
vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 (PubMed 9030196); Alvarez et
al., 2003 (PubMed 12802079)).(supplied by OMIM, Jan 2009)

UniProtKB/Swiss-Prot: RAB1B_HUMAN, Q9H0U4
Function: Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi
compartments

Gene Wiki entry for RAB1B


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB1B gene promoter:
         E2F-4   E2F-3a   E2F-5   MAZR   E2F-2   LCR-F1   c-Ets-1   AREB6   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB1B promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.1

RAB1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB1B gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P066036:  view genomic region     (about GC identifiers)

Start:
66,036,004 bp from pter      End:
66,044,963 bp from pter
Size:
8,960 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RAB1B_HUMAN, Q9H0U4 (See protein sequence)
Recommended Name: Ras-related protein Rab-1B  
Size: 201 amino acids; 22171 Da
Subunit: Interacts with MICAL1, MICAL2 and MICAL3. Interacts with GDI1; the interaction requires the GDP-bound state.
Interacts with CHM/REP1; the interaction requires the GDP-bound form and is necessary for prenylation by GGTase II
Subcellular location: Membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Note=Targeted by REP1 to membranes of
specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between
these two compartments. In the GDP-form, colocalizes with GDI in the cytoplasm (By similarity)
Miscellaneous: Rab-1B binds GTP and GDP and possesses intrinsic GTPase activity (By similarity)
4 PDB 3D structures from and Proteopedia for RAB1B:
3JZA (3D)        3NKV (3D)        4HLQ (3D)        4I1O (3D)    
Secondary accessions: A8K7S1

Explore the universe of human proteins at neXtProt for RAB1B: NX_Q9H0U4

Post-translational modifications:

  • Prenylated; by GGTase II, only after interaction of the substrate with Rab escort protein 1 (REP1)1
  • AMPylation at Tyr-77 by L.pneumophila DrrA occurs in the switch 2 region and leads to moderate inactivation of the
  • GTPase activity. It appears to prolong the lifetime of the GTP state of RAB1B by restricting access of GTPase
    effectors to switch 2 and blocking effector-stimulated GTP hydrolysis, thereby rendering RAB1B constitutively active.
    It is later de-AMPylated by L.pneumophila SidD, releasing RAB1B from bacterial phagosomes1
  • Phosphocholinated at Ser-76 by L.pneumophila AnkX, leading to displace GDP dissociation inhibitors (GDI). Both
  • GDP-bound and GTP-bound forms can be phosphocholinated. Dephosphocholinated by L.pneumophila Lem3, restoring
    accessibility to L.pneumophila GTPase effector LepB1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H0U4

  • RAB1B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_112243.1  
    ENSEMBL proteins: 
     ENSP00000310226   ENSP00000435195  
    Reactome Protein details: Q9H0U4
    Human Recombinant Protein Products: 
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    ProSpec Recombinant Protein for RAB1B
    Uscn Proteins for RAB1B

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005794Golgi apparatus IDA--
    GO:0016020membrane IEA--


    RAB1B for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RAB1B


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RAB1B for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type

    Graphical View of Domain Structure for InterPro Entry Q9H0U4

    ProtoNet protein and cluster: Q9H0U4

    1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB1B_HUMAN, Q9H0U4
    Similarity: Belongs to the small GTPase superfamily. Rab family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RAB1B_HUMAN, Q9H0U4
    Function: Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi
    compartments

    miRNA
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    8/32 QIAGEN miScript miRNA Assays for microRNAs that regulate RAB1B (see all 32):
    hsa-miR-676 hsa-miR-502-5p hsa-miR-300 hsa-miR-1197 hsa-miR-3660 hsa-miR-331-3p hsa-miR-103a hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidRAB1B 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005525GTP binding IDA--


    RAB1B for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for RAB1B:
     Decreased Tat-dependent transc 

    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Rab1b):
     normal 

    RAB1B for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1M Phase
    M Phase1.00
    Mitotic M-M/G1 phases0.88
    2Cell Cycle
    Cell Cycle1.00
    Cell Cycle, Mitotic0.84
    3Clearance of Nuclear Envelope Membranes from Chromatin
    Mitotic Prophase0.26
    Golgi Cisternae Pericentriolar Stack Reorganization0.00
    4Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for RAB1B
        Epithelial Tight Junctions

    5/6        Reactome Pathways for RAB1B (see all 6)
        Golgi Cisternae Pericentriolar Stack Reorganization
    Mitotic Prophase
    Cell Cycle
    M Phase
    Mitotic M-M/G1 phases



    RAB1B for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAB1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/19 Interacting proteins for RAB1B (Q9H0U42, 3 ENSP000003102264) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RUSC2Q8N2Y82, 3, ENSP000003551774MINT-61270 MINT-61269 MINT-61266 I2D: score=3 STRING: ENSP00000355177
    GOLGA2Q083792, 3, ENSP000004160974MINT-61265 I2D: score=3 STRING: ENSP00000416097
    MICAL1Q8TDZ22, 3, ENSP000003516644MINT-61264 I2D: score=3 STRING: ENSP00000351664
    OCRLQ019682MINT-8184698 MINT-8184889 MINT-8184876
    CHMP243863, ENSP000003503864I2D: score=2 STRING: ENSP00000350386
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport IEA--


    RAB1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RAB1B for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RAB1B

    1 HMDB Compound for RAB1B    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    2 Novoseek chemical compound relationships for RAB1B gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gdp 67.1 3 8325834 (1), 9437002 (1), 8836150 (1)
    gtp 56.7 1 8325834 (1)

    Search CenterWatch for drugs/clinical trials and news about RAB1B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB1B gene: 
    NM_030981.2  

    Unigene Cluster for RAB1B:

    RAB1B, member RAS oncogene family
    Hs.300816  [show with all ESTs]
    Unigene Representative Sequence: AK125412
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000311481(uc001ohf.3) ENST00000527397

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    hsa-miR-676 hsa-miR-502-5p hsa-miR-300 hsa-miR-1197 hsa-miR-3660 hsa-miR-331-3p hsa-miR-103a hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidRAB1B 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AJ245875.1 AK125412.1 AK292086.1 AK315333.1 AL136635.1 BC028331.1 BC071169.1 CR533462.1 
    U66621.1 

    24/29 DOTS entries (see all 29):

    DT.100786824  DT.91908062  DT.100757341  DT.121192845  DT.99998569  DT.120735097  DT.120735063  DT.216580 
    DT.92041333  DT.100786834  DT.91652303  DT.91867251  DT.92450775  DT.95177030  DT.97864437  DT.99985353 
    DT.100770591  DT.100786826  DT.100786831  DT.120735110  DT.91695929  DT.92450787  DT.92450794  DT.95177025 

    24/705 AceView cDNA sequences (see all 705):

    BI764071 CA395480 BM560456 BQ878543 BI906801 BI837011 BE170824 BQ893347 
    BX107600 BM750031 BQ718215 AI350693 BU627109 AA434103 CA396415 W95610 
    BQ722819 BM930036 CR624810 CF131503 BM476064 BM916989 AA375777 BI819274 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for RAB1B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b
    SP1:                                          
    SP2:                    -                     


    ECgene alternative splicing isoforms for RAB1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCAGGCATTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See RAB1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB1B

    SOURCE GeneReport for Unigene cluster: Hs.300816
        SABiosciences Custom PCR Arrays for RAB1B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB1B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RAB1B gene from 6/30 species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    RAB1B6
    --
    76(a)
    72(a)
    possible ortholog
    1 ↔ 1
    GL343635.1(211685-216100)
    GL343519.1(94714-98588)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc560492 similar to RAB1, member RAS oncogene family 81.37(n)   394117  BC047816.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rab13 Rho small monomeric GTPase 83(a)
    (best of 3)
      93D2   --
    worm
    (Caenorhabditis elegans)
    Secernentea rab-13   -- 79(a)
    (best of 4)
      V(1262845-1263838)   --
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RA-51 Ras-related protein RABD2A 64.33(n)
    76.5(a)
      837023  NM_100093.3  NP_171715.1 
    rice
    (Oryza sativa)
    Liliopsida Os.78692 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 78.09(n)    NM_189540.1 


    ENSEMBL Gene Tree for RAB1B (if available)
    TreeFam Gene Tree for RAB1B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB1B gene
    RAB102  RAB192  RAB432  RAB182  RAB262  RAB8A2  RAB372  RAB352  
    RAB8B2  RAB122  RAB302  RAB1A2  RAB132  
    18/103 SIMAP similar genes for RAB1B using alignment to 3 protein entries:     RAB1B_HUMAN (see all proteins) (see all similar genes):
    rab1b    RAB1C    RAB8B    DKFZp686J07132    RAB1A    RAB30
    RAB36    RAB10    RAB8A    RAB13    RAB43    RAB33A
    NRAS    RAB6A'    RAB15    RAB39B    RAB5C    KRAS

    RAB1B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/165 NCBI SNPs in RAB1B are shown (see all 165    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs38147391,2
    C,F,H,--66035979(-) TCTCCA/GACTCA 1 -- us2k120Minor allele frequency- G:0.29EA MN NS NA WA 4106
    rs112274401,2
    C,--66036041(+) GACGTT/GTGCGC 1 -- us2k13Minor allele frequency- G:0.08NA WA 122
    rs1996567421,2
    --66036141(+) GCCGCC/TGCCGC 1 -- ut510--------
    rs1506274441,2
    --66036293(+) GCTGA-/CCCCCCC 1 -- int10--------
    rs1877046081,2
    --66036435(+) CCAGGC/TCTTAT 1 -- int10--------
    rs1178270121,2
    F,--66036564(+) TGGGCC/TCTTTA 1 -- int11Minor allele frequency- T:0.05NA 120
    rs1510239851,2
    --66036852(+) TTTAGA/TTGAAT 1 -- int10--------
    rs1932289921,2
    --66036858(+) TGAATA/GTGGAA 1 -- int10--------
    rs743949701,2
    --66037040(+) TCTCAG/CATTTC 1 -- int11Minor allele frequency- C:0.01WA 118
    rs107507811,2
    C,F,A,H,--66037270(+) AGATGA/GTGCAT 1 -- int18Minor allele frequency- G:0.20NA WA EA 370

    HapMap Linkage Disequilibrium report for RAB1B (66036004 - 66044963 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for RAB1B: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RAB1B for disorders           About GeneDecksing

    OMIM gene information: 612565    OMIM disorders: --

    6 diseases for RAB1B:    About MalaCards
    platelet storage pool deficiency    legionnaires' disease    herpes simplex    rabies
    melanoma    malaria

    1 disease from the University of Copenhagen DISEASES database for RAB1B:
    Platelet storage pool deficiency
    Human Genome Epidemiology (HuGE) Navigator: RAB1B (1 document)

    Export disorders for RAB1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB1B gene, integrated from 9 sources (see all 51):
    (articles sorted by number of sources associating them with RAB1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The putative 'switch 2' domain of the Ras-related GTPase, Rab1B, plays an essential role in the interaction with Rab escort protein. (PubMed id 9437002)1, 2, 9 Overmeyer J.H.... Maltese W.A. (1998)
    2. Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells. (PubMed id 8836150)1, 2, 9 Wilson A.L.... Maltese W.A. (1996)
    3. The MICAL proteins and rab1: a possible link to the cytoskeleton? (PubMed id 15694364)1, 2 Fischer J.... Barnekow A. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    6. RAB GTPases expressed in human melanoma cells. (PubMed id 9030196)1, 3 Chen D.... Gahl W.A. (1997)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Human immunodeficiency virus type 1 envelope proteins traffic toward virion assembly sites via a TBC1D20/Rab1-regulated pathway. (PubMed id 22260459)1 Nachmias D....Bacharach E. (2012)
    9. Catalytic mechanism of a mammalian Rab^RabGAP complex in atomic detail. (PubMed id 23236136)1 Gavriljuk K....Gerwert K. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81876 HGNC: 18370 AceView: KLC2andRAB1B Ensembl:ENSG00000174903 euGenes: HUgn81876
    ECgene: RAB1B H-InvDB: RAB1B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB1B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB1B Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB1B gene:
    Search GeneIP for patents involving RAB1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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