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Aliases for RAB19 Gene

Aliases for RAB19 Gene

  • RAB19, Member RAS Oncogene Family 2 3
  • RAB19B 3 4
  • GTP-Binding Protein RAB19B 3
  • Ras-Related Protein Rab-19 3

External Ids for RAB19 Gene

Summaries for RAB19 Gene

GeneCards Summary for RAB19 Gene

RAB19 (RAB19, Member RAS Oncogene Family) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is RAB42.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB19 Gene

Genomics for RAB19 Gene

Genomic Location for RAB19 Gene

Start:
140,404,043 bp from pter
End:
140,426,853 bp from pter
Size:
22,811 bases
Orientation:
Plus strand

Genomic View for RAB19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RAB19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB19 Gene

Regulatory Elements for RAB19 Gene

Proteins for RAB19 Gene

  • Protein details for RAB19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4D1S5-RAB19_HUMAN
    Recommended name:
    Ras-related protein Rab-19
    Protein Accession:
    A4D1S5
    Secondary Accessions:
    • A4D1S6
    • B2RTS6
    • B5MDR2
    • Q9UL27

    Protein attributes for RAB19 Gene

    Size:
    217 amino acids
    Molecular mass:
    24400 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RAB19 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RAB19 Gene

Proteomics data for RAB19 Gene at MOPED

Post-translational modifications for RAB19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAB19 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAB19 Gene

Domains for RAB19 Gene

Gene Families for RAB19 Gene

HGNC:
  • RAB :RAB, member RAS oncogene

Protein Domains for RAB19 Gene

UniProtKB/Swiss-Prot:

RAB19_HUMAN
Family:
  • Belongs to the small GTPase superfamily. Rab family.:
    • A4D1S5
genes like me logo Genes that share domains with RAB19: view

Function for RAB19 Gene

Gene Ontology (GO) - Molecular Function for RAB19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity IBA --
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with RAB19: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RAB19 Gene

Localization for RAB19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB19 Gene

Cell membrane; Lipid-anchor; Cytoplasmic side.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RAB19 Gene COMPARTMENTS Subcellular localization image for RAB19 gene
Compartment Confidence
plasma membrane 5
cytosol 3
nucleus 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for RAB19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005737 cytoplasm --
GO:0005768 endosome IBA --
GO:0005794 Golgi apparatus IBA --
genes like me logo Genes that share ontologies with RAB19: view

Pathways for RAB19 Gene

SuperPathways for RAB19 Gene

No Data Available

Interacting Proteins for RAB19 Gene

Gene Ontology (GO) - Biological Process for RAB19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006184 obsolete GTP catabolic process --
GO:0006886 intracellular protein transport IBA --
GO:0006913 nucleocytoplasmic transport --
GO:0007165 signal transduction --
GO:0007264 small GTPase mediated signal transduction --
genes like me logo Genes that share ontologies with RAB19: view

No data available for Pathways by source for RAB19 Gene

Transcripts for RAB19 Gene

mRNA/cDNA for RAB19 Gene

(7) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB19 Gene

RAB19, member RAS oncogene family:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RAB19 Gene

No ASD Table

Relevant External Links for RAB19 Gene

GeneLoc Exon Structure for
RAB19
ECgene alternative splicing isoforms for
RAB19

Expression for RAB19 Gene

mRNA expression in normal human tissues for RAB19 Gene

mRNA differential expression in normal tissues according to GTEx for RAB19 Gene

This gene is overexpressed in Whole Blood (8.2), Pancreas (7.9), Colon - Transverse (6.9), Pituitary (6.4), and Kidney - Cortex (5.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAB19 Gene

SOURCE GeneReport for Unigene cluster for RAB19 Gene Hs.583545

genes like me logo Genes that share expressions with RAB19: view

Orthologs for RAB19 Gene

This gene was present in the common ancestor of animals.

Orthologs for RAB19 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RAB19 36
  • 99.54 (n)
  • 100 (a)
RAB19 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RAB19 36
  • 86.18 (n)
  • 88.02 (a)
RAB19 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RAB19 36
  • 87.1 (n)
  • 89.4 (a)
RAB19 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rab19 36
  • 86.33 (n)
  • 88.94 (a)
Rab19 16
Rab19 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia RAB19 37
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RAB19 37
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rab19 36
  • 86.02 (n)
  • 90.32 (a)
chicken
(Gallus gallus)
Aves RAB19 36
  • 74.92 (n)
  • 79.91 (a)
RAB19 37
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rab19 36
  • 72.36 (n)
  • 73.66 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC555645 36
  • 65.57 (n)
  • 65.26 (a)
RAB19 37
  • 63 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Rab-RP3 37
  • 47 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea rab-19 37
  • 46 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 46 (a)
OneToMany
Species with no ortholog for RAB19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RAB19 Gene

ENSEMBL:
Gene Tree for RAB19 (if available)
TreeFam:
Gene Tree for RAB19 (if available)

Paralogs for RAB19 Gene

genes like me logo Genes that share paralogs with RAB19: view

Variants for RAB19 Gene

Sequence variations from dbSNP and Humsavar for RAB19 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2001941 -- 140,417,762(-) cccct(A/G)cagcg intron-variant
rs2001942 -- 140,417,611(-) GAAGC(C/T)CGTAT intron-variant
rs2948382 -- 140,418,332(+) ggatt(C/G)cctga intron-variant
rs2948383 -- 140,418,395(+) aaaat(A/C)caaaa intron-variant
rs2948385 -- 140,424,621(+) TCTCT(A/C)TATAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RAB19 Gene

Variant ID Type Subtype PubMed ID
esv2735212 CNV Deletion 23290073
nsv522190 CNV Gain 19592680

Relevant External Links for RAB19 Gene

HapMap Linkage Disequilibrium report
RAB19

Disorders for RAB19 Gene

No disorders were found for RAB19 Gene.

No data available for UniProtKB/Swiss-Prot for RAB19 Gene

Publications for RAB19 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PMID: 19056867) Gonzales P.A. … Knepper M.A. (J. Am. Soc. Nephrol. 2009) 3
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for RAB19 Gene

Sources for RAB19 Gene

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