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Aliases for RAB19 Gene

Aliases for RAB19 Gene

  • RAB19, Member RAS Oncogene Family 2 3 5
  • RAB19B 3 4
  • GTP-Binding Protein RAB19B 3

External Ids for RAB19 Gene

Previous GeneCards Identifiers for RAB19 Gene

  • GC07P139754
  • GC07P140103
  • GC07P134397

Summaries for RAB19 Gene

GeneCards Summary for RAB19 Gene

RAB19 (RAB19, Member RAS Oncogene Family) is a Protein Coding gene. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB33A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB19 Gene

Genomics for RAB19 Gene

Regulatory Elements for RAB19 Gene

Enhancers for RAB19 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RAB19 on UCSC Golden Path with GeneCards custom track

Promoters for RAB19 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RAB19 on UCSC Golden Path with GeneCards custom track

Genomic Location for RAB19 Gene

140,403,822 bp from pter
140,426,878 bp from pter
23,057 bases
Plus strand

Genomic View for RAB19 Gene

Genes around RAB19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RAB19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RAB19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RAB19 Gene

Proteins for RAB19 Gene

  • Protein details for RAB19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ras-related protein Rab-19
    Protein Accession:
    Secondary Accessions:
    • A4D1S6
    • B2RTS6
    • B5MDR2
    • Q9UL27

    Protein attributes for RAB19 Gene

    217 amino acids
    Molecular mass:
    24400 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for RAB19 Gene


neXtProt entry for RAB19 Gene

Proteomics data for RAB19 Gene at MOPED

Post-translational modifications for RAB19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RAB19 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RAB19 Gene

Domains & Families for RAB19 Gene

Gene Families for RAB19 Gene

Protein Domains for RAB19 Gene

Suggested Antigen Peptide Sequences for RAB19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the small GTPase superfamily. Rab family.
  • Belongs to the small GTPase superfamily. Rab family.
genes like me logo Genes that share domains with RAB19: view

Function for RAB19 Gene

genes like me logo Genes that share phenotypes with RAB19: view

Animal Models for RAB19 Gene

MGI Knock Outs for RAB19:

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RAB19 Gene

Localization for RAB19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RAB19 Gene

Cell membrane; Lipid-anchor; Cytoplasmic side.

Subcellular locations from

Jensen Localization Image for RAB19 Gene COMPARTMENTS Subcellular localization image for RAB19 gene
Compartment Confidence
extracellular 5
cytosol 3
plasma membrane 3
nucleus 2
cytoskeleton 1

No data available for Gene Ontology (GO) - Cellular Components for RAB19 Gene

Pathways & Interactions for RAB19 Gene

SuperPathways for RAB19 Gene

No Data Available

Interacting Proteins for RAB19 Gene

Gene Ontology (GO) - Biological Process for RAB19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
genes like me logo Genes that share ontologies with RAB19: view

No data available for Pathways by source and SIGNOR curated interactions for RAB19 Gene

Drugs & Compounds for RAB19 Gene

No Compound Related Data Available

Transcripts for RAB19 Gene

mRNA/cDNA for RAB19 Gene

(7) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RAB19 Gene

RAB19, member RAS oncogene family:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RAB19 Gene

No ASD Table

Relevant External Links for RAB19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RAB19 Gene

mRNA expression in normal human tissues for RAB19 Gene

mRNA differential expression in normal tissues according to GTEx for RAB19 Gene

This gene is overexpressed in Whole Blood (x8.2), Pancreas (x7.9), Colon - Transverse (x6.9), Pituitary (x6.4), and Kidney - Cortex (x5.4).

Protein differential expression in normal tissues from HIPED for RAB19 Gene

This gene is overexpressed in Cerebrospinal fluid (15.4), Platelet (11.6), and Monocytes (10.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for RAB19 Gene

SOURCE GeneReport for Unigene cluster for RAB19 Gene Hs.583545

genes like me logo Genes that share expression patterns with RAB19: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RAB19 Gene

Orthologs for RAB19 Gene

This gene was present in the common ancestor of animals.

Orthologs for RAB19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RAB19 35
  • 86.18 (n)
  • 88.02 (a)
RAB19 36
  • 88 (a)
(Canis familiaris)
Mammalia RAB19 35
  • 87.1 (n)
  • 89.4 (a)
RAB19 36
  • 89 (a)
(Mus musculus)
Mammalia Rab19 35
  • 86.33 (n)
  • 88.94 (a)
Rab19 16
Rab19 36
  • 89 (a)
(Pan troglodytes)
Mammalia RAB19 35
  • 99.54 (n)
  • 100 (a)
RAB19 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Rab19 35
  • 86.02 (n)
  • 90.32 (a)
(Monodelphis domestica)
Mammalia RAB19 36
  • 85 (a)
(Ornithorhynchus anatinus)
Mammalia RAB19 36
  • 82 (a)
(Gallus gallus)
Aves RAB19 35
  • 74.92 (n)
  • 79.91 (a)
RAB19 36
  • 78 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rab19 35
  • 72.36 (n)
  • 73.66 (a)
(Danio rerio)
Actinopterygii LOC555645 35
  • 65.57 (n)
  • 65.26 (a)
RAB19 36
  • 63 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rab-RP3 36
  • 47 (a)
(Caenorhabditis elegans)
Secernentea rab-19 36
  • 46 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 46 (a)
Species with no ortholog for RAB19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RAB19 Gene

Gene Tree for RAB19 (if available)
Gene Tree for RAB19 (if available)

Paralogs for RAB19 Gene

genes like me logo Genes that share paralogs with RAB19: view

Variants for RAB19 Gene

Sequence variations from dbSNP and Humsavar for RAB19 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs12667917 -- 140,418,009(+) CTCCA(C/T)GGGCC intron-variant
rs12667942 -- 140,408,853(+) tcccc(A/G)actca intron-variant
rs12671002 -- 140,408,655(+) ATTTT(C/T)AGTAG intron-variant
rs12703834 -- 140,407,872(+) GGACT(A/G)GTTCC intron-variant
rs12703835 -- 140,407,951(+) GCTCC(A/C/G)CCTCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RAB19 Gene

Variant ID Type Subtype PubMed ID
esv2735212 CNV Deletion 23290073
nsv522190 CNV Gain 19592680

Variation tolerance for RAB19 Gene

Residual Variation Intolerance Score: 87.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.21; 62.10% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RAB19 Gene

Disorders for RAB19 Gene

Relevant External Links for RAB19

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RAB19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAB19 Gene

Publications for RAB19 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 67
  2. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PMID: 19056867) Gonzales P.A. … Knepper M.A. (J. Am. Soc. Nephrol. 2009) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for RAB19 Gene

Sources for RAB19 Gene