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RAB17 Gene

protein-coding   GIFtS: 57
GCID: GC02M238499

RAB17, Member RAS Oncogene Family

  Search for RAB17
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
RAB17, Member RAS Oncogene Family1 2
Ras-Related Protein Rab-172

External Ids:    HGNC: 165231   Entrez Gene: 642842   Ensembl: ENSG000001248397   OMIM: 6022065   UniProtKB: Q9H0T73   
ORGUL members:         

Export aliases for RAB17 gene to outside databases

Previous GC identifers: GC02M236532 GC02M237164 GC02M238769 GC02M238264 GC02M238147 GC02M230273


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB17 Gene:
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an
epithelial cell-specific GTPase (Lutcke et al., 1993 (PubMed 8486736)).(supplied by OMIM, Oct 2009)

GeneCards Summary for RAB17 Gene:
RAB17 (RAB17, member RAS oncogene family) is a protein-coding gene. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RAB20.

UniProtKB/Swiss-Prot: RAB17_HUMAN, Q9H0T7
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed
movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite
side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of
immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking
through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport
and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May
also play a role in cell migration

Gene Wiki entry for RAB17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB17 gene promoter:
         TBP   AP-1   Lmo2   LCR-F1   NF-E2 p45   FOXL1   Msx-1   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): RAB17 promoter sequence
   Search Chromatin IP Primers for RAB17

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

RAB17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB17 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M238499:  view genomic region     (about GC identifiers)

Start:
238,482,965 bp from pter      End:
238,510,257 bp from pter
Size:
27,293 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAB17_HUMAN, Q9H0T7 (See protein sequence)
Recommended Name: Ras-related protein Rab-17  
Size: 212 amino acids; 23491 Da
Secondary accessions: Q53QV6 Q6IA73 Q9BVU1 Q9H9U9

Explore the universe of human proteins at neXtProt for RAB17: NX_Q9H0T7

Explore proteomics data for RAB17 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB17 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071894.1  
    ENSEMBL proteins: 
     ENSP00000375858   ENSP00000264601   ENSP00000386792   ENSP00000389332   ENSP00000386589  
     ENSP00000400240   ENSP00000401495   ENSP00000443461  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q9H0T7

    ProtoNet protein and cluster: Q9H0T7

    1 Blocks protein domain: IPB001806 Transforming protein P21 RAS signature

    UniProtKB/Swiss-Prot: RAB17_HUMAN, Q9H0T7
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB17           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB17_HUMAN, Q9H0T7
    Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
    transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
    GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
    for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed
    movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite
    side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of
    immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking
    through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport
    and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May
    also play a role in cell migration
    Induction: Up-regulated by forskolin probably through the transcription factor MITF

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005515protein binding ----
    GO:0005525GTP binding IEA--
    GO:0019003GDP binding IDA--
         
    Find genes that share ontologies with RAB17           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB17
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    Addgene plasmids for RAB17 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB17_HUMAN, Q9H0T7: Recycling endosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Cell
    projection, dendrite (By similarity). Note=May also localize at the basolateral and apical plasma membrane. In
    neurons, localizes to the cell body and dendritic shaft and spine (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    plasma membrane4
    mitochondrion3
    cytosol2
    extracellular1

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0016020membrane ----
    GO:0016323basolateral plasma membrane ISS--

    Find genes that share ontologies with RAB17           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB17 About    
    See pathways by source

    SuperPathContained pathways About
    1Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions0.36

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for RAB17
        Epithelial Tight Junctions



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB17
    Interactions:

        Search GeneGlobe Interaction Network for RAB17

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for RAB17 (Q9H0T72, 3 ENSP000002646014) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUDT3O959892, 3MINT-63333 I2D: score=5 
    S100A8P051092, 3MINT-63399 I2D: score=4 
    ACVR1Q047713, ENSP000002636404I2D: score=3 STRING: ENSP00000263640
    RAB7AP511493, ENSP000002650624I2D: score=1 STRING: ENSP00000265062
    RABAC1Q9UI143, ENSP000002220084I2D: score=1 STRING: ENSP00000222008
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    Gene Ontology (GO): Selected biological process terms (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002415immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor ISS--
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----

    Find genes that share ontologies with RAB17           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB17



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB17 gene: 
    NM_022449.3  

    Unigene Cluster for RAB17:

    RAB17, member RAS oncogene family
    Hs.44278  [show with all ESTs]
    Unigene Representative Sequence: BX647412
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392001 ENST00000264601(uc002vwz.2 uc002vxb.2) ENST00000477149
    ENST00000409576 ENST00000414278 ENST00000466244 ENST00000409822 ENST00000411462
    ENST00000430445 ENST00000416106 ENST00000487008 ENST00000538644
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    Additional mRNA sequence: 

    AK022600.1 AK225423.1 AL136645.1 BC000929.2 BC007907.2 BC009827.2 BC023661.2 BC050426.1 
    BX647412.1 CR457282.1 CR533454.1 NR_033308.1 

    8 DOTS entries:

    DT.120934537  DT.445338  DT.97843061  DT.100657336  DT.95368759  DT.100657337  DT.95282591  DT.100657637 

    Selected AceView cDNA sequences (see all 160):

    CR606784 CA391377 CR624533 AI826494 BE891531 CB141213 NM_022449 AW071098 
    BU160968 AA913129 BF477737 CB135611 AL548167 CK430084 CB135219 AI028133 
    CR591120 BU956864 CR608634 AW009045 BU957436 CR626220 AI206424 BQ920683 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RAB17 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f
    SP1:                    -     -     -                 -     -                                             
    SP2:                          -     -                 -     -                                             
    SP3:                                -                 -     -                                             
    SP4:                                -     -           -     -                                             
    SP5:                    -     -     -                                                                     


    ECgene alternative splicing isoforms for RAB17

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB17 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCTCCCGGC
    RAB17 Expression
    About this image


    RAB17 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Mandibular Arch Muscles
     
     Liver (Hepatobiliary System)
             Hematopoietic Stem Cells Liver Bud
     
     NULL (Uncategorized)
             Mesenchymal Progenitor Cells - Passage 2
     
     Blood (Cardiovascular System)
             Hematopoietic Stem Cells Liver Bud
     
     Kidney (Urinary System)
    RAB17 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB17 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.44278

    UniProtKB/Swiss-Prot: RAB17_HUMAN, Q9H0T7
    Tissue specificity: Expressed in melanocytes (at protein level)

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB17

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB17 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab171 , 5 RAB17, member RAS oncogene family1, 5 77.99(n)1
    75.47(a)1
      1 (45.84 cM)5
    193291  NM_008998.41  NP_033024.11 
     909581335 
    chicken
    (Gallus gallus)
    Aves RAB171 RAB17, member RAS oncogene family 64.09(n)
    59.28(a)
      424017  XM_004942491.1  XP_004942548.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB176
    RAB17, member RAS oncogene family
    52(a)
    1 ↔ 1
    1(123480449-123496448)
    fruit fly
    (Drosophila melanogaster)
    Insecta chrw6
    chrowded
    26(a)
    1 → many
    2R(19407362-19411096)


    ENSEMBL Gene Tree for RAB17 (if available)
    TreeFam Gene Tree for RAB17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB17 gene
    RAB202  RAB5C2  ENSG000002672612  RAB312  RAB5B2  RAB212  RAB5A2  RAB242  
    RAB22A2  
    Selected SIMAP similar genes for RAB17 using alignment to 8 protein entries:     RAB17_HUMAN (see all proteins) (see all similar genes):
    rab1b    DKFZp686J06205    RAB30    RAB5C    RAB14    RAB6B
    RAB43    RAB25    RAB18    RAB39B    RAB41    RAB5A
    RAB11B    RAB19    DKFZp313C1541    RAB5B    RAB39A    RAB8B

    Find genes that share paralogs with RAB17           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB17 (see all 557)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1386547011,2
    --238482488(+) GAGTTC/TCCCCA 2 -- int10--------
    rs1140376131,2
    F--238482562(+) ACCTCT/CGCACG 2 -- int11Minor allele frequency- C:0.02WA 118
    rs101901031,2
    C,F,A,H--238482636(+) ggcccT/Cgtgca 2 -- int114Minor allele frequency- C:0.07NS EA NA WA 1086
    rs67166901,2
    C,F,A--238482663(+) gaaccA/C/Gtgagc 2 -- int110WA NA CSA EA 371
    rs101875451,2
    C,F,A--238482671(+) agcccA/Cataaa 2 -- int13Minor allele frequency- C:0.12WA 122
    rs1492517711,2
    --238482919(+) ACCATA/CCACCA 2 -- int10--------
    rs1895782991,2
    --238482935(+) AGTGCC/TCTGCC 2 -- int10--------
    rs1444864791,2
    C--238483117(+) ACTGGC/TGCCAC 2 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.00EU 593
    rs67661,2
    C,F,O,A,H--238483164(-) TTTCCA/GCATCT 2 -- ut31 nc-transcript-variantese335Minor allele frequency- G:0.45MN EA NA NS WA CSA EU 5444
    rs2016592171,2
    F--238483197(+) GTCATC/TGCTCC 2 -- ut31 nc-transcript-variant1Minor allele frequency- T:0.01EU 571

    HapMap Linkage Disequilibrium report for RAB17 (238482965 - 238510257 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for RAB17:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv876056CNV Loss21882294
    esv28512CNV Loss19812545
    nsv3229CNV Loss18451855
    nsv876057CNV Gain21882294
    nsv876054CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB17
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB17

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602206    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for RAB17:
    Hemophagocytic lymphohistiocytosis

    Find genes that share disorders with RAB17           About GenesLikeMe

    Genetic Association Database (GAD): RAB17
    Human Genome Epidemiology (HuGE) Navigator: RAB17 (1 document)

    Export disorders for RAB17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB17 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with RAB17)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin- beta2. (PubMed id 22328529)1, 2 von Thun A.... Norman J.C. (J. Cell Sci. 2012)
    2. The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. (PubMed id 21291502)1, 2 Beaumont K.A.... Stow J.L. (Traffic 2011)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    7. Rab17 localizes to recycling endosomes and regulates receptor-mediated transcytosis in epithelial cells. (PubMed id 9624171)1, 3 Hunziker W. and Peters P.J. (J. Biol. Chem. 1998)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    9. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    10. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M....Figeys D. (Mol. Syst. Biol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64284 HGNC: 16523 AceView: RAB17 Ensembl:ENSG00000124839 euGenes: HUgn64284
    ECgene: RAB17 H-InvDB: RAB17

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for RAB17 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB17 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB17 gene:
    Search GeneIP for patents involving RAB17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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