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Aliases & Descriptions for RAB13
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| GIG4 2 | | OTTHUMP00000034758 2 |
| | | Descriptions |
|---|
| Cell growth-inhibiting gene 4 protein 3 | | RAB13, member RAS oncogene family 2 | | RAS-associated protein RAB13 2 | | growth-inhibiting gene 4 protein 2 |
|
| | Search outside databases for aliases for RAB13 genePrevious GC identifers: GC01M151770 GC01M149685 GC01M150729 GC01M151170 GC01M150767 |
Summaries for RAB13(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: RAB13_HUMAN, P51153Function: Could participate in polarized transport, in the assembly and/or the activity of tight junctionsGene Wiki entry for RAB13 |
Genomic Location for RAB13
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the RAB13 gene 
Entrez Gene cytogenetic band: 1q21.2 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21.2RAB13 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M152220:
(about GC identifiers)
Start:
|
152,220,751 bp from pter |
End:
|
152,225,430 bp from pter |
Size:
|
4,680 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000001.9 NT_004487.18
| Proteins for RAB13
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: RAB13_HUMAN, P51153 (See
protein sequence)Recommended Name: Ras-related protein Rab-13 Size: 203 amino acids; 22774 Da
Subcellular location: Cell junction, tight junction. Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Note=Cytoplasmic tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions
Secondary accessions: A8K6B5 Q5U0A6 Q6GPG6 Q96GU4Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_002861.1
ENSEMBL proteins: ENSP00000357564
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: RAB13 
5/7 Gene Ontology (GO) cellular component terms (links to tree view) (see all 7
): About this table
Antibodies for RAB13: Assays for RAB13: | Protein
Domains/ Families for RAB13(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P51153
ProtoNet protein and cluster: P51153 1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature
UniProtKB/Swiss-Prot: RAB13_HUMAN, P51153Similarity: Belongs to the small GTPase superfamily. Rab family | Gene Function for RAB13
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002870
Applied Biosystems Silencer® siRNAs for RAB13
Sigma-Aldrich siRNA for RAB13  Sigma-Aldrich shRNA Panels and shRNA for RAB13  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002870                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_002870                                  untagged cDNA clones in CMV expression vector (see all 2): NM_002870 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_002870
UniProtKB/Swiss-Prot: RAB13_HUMAN, P51153Function: Could participate in polarized transport, in the assembly and/or the activity of tight junctionsGenatlas biochemistry entry for RAB13:Ras-related small GTPase,component of the junctional complex of polarized epithelial cells,specific regulator of vesicular trafficking,cycling between cytosolic and membrane-bound forms under the control of PDE6B,expressed in skeletal muscle3 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for RAB13
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| 1 Sigma-Aldrich "Your Favorite Gene" Pathway for RAB13 (Your Favorite Gene powered by Ingenuity) 
Gene Network CentralTM Interacting Genes and Proteins Network for RAB13 
4 Interacting proteins for RAB13 (P511532 ENSP000003575643) via UniProtKB, MINT, and/or STRINGAbout this table
4 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for RAB13(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|  |
Enzo Life Sciences drugs & compounds for RAB13 |
Browse Tocris compounds for RAB13
|
Transcripts for RAB13(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002870
Sigma-Aldrich siRNA for RAB13  Sigma-Aldrich shRNA Panels and shRNA for RAB13  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_002870 REFSEQ mRNAs for RAB13 gene: NM_002870.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_002870               OriGene GFP tagged cDNA clone in CMV expression vector: NM_002870                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_002870                                  untagged cDNA clones in CMV expression vector (see all 2): NM_002870  Additional cDNA sequence: AF498948.1 AK128675.1 AK291580.1 AY423722.1 BC000799.1 BC009227.2 BC073168.1 BC094846.1 BT019700.1 BT019701.1 CR610750.1 CR612138.1 CR614708.1 X75593.1 22 DOTS entries: DT.447954 DT.100782988 DT.121436379 DT.121176064 DT.92391355 DT.95072479 DT.100030339 DT.100782989 DT.97844584 DT.100782992 DT.100817421 DT.102833631 DT.102833632 DT.121436448 DT.121436509 DT.121436538 DT.121436539 DT.87002597 DT.91753960 DT.91753962 DT.92333738 DT.97860931 24/930 AceView cDNA sequences (see all 930
):CB160321 BU689274 AI032032 AI568647 AI571667 CB148747 T30169 BM887740 CB991161 BQ027177 CA310680 BC004239 BM997537 BU173893 BE267959 BM555992 BM312894 AW248680 BU944604 BE792677 BE890968 BI835067 CA777260 BM820241
highest scoring ESTs for RAB13:X75593 AA296394 AA545802 AA970570 AF498948 AI079191 AK128675 AL519821 AL570891 AU123205 Unigene Cluster for RAB13: RAB13, member RAS oncogene family Hs.151536 [show with all ESTs]Unigene Representative Sequence: AK128675
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000368575
|
Expression for RAB13
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| RAB13 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for RAB13
1 / 2 / 3 4 probe-sets matching RAB13 gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: GTCTTTCTTG
SOURCE GeneReport for Unigene cluster: Hs.151536
Expression variation in blood from EXPOLDB for RAB13 UniProtKB/Swiss-Prot: RAB13_HUMAN, P51153Tissue specificity: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells |
Orthologs for RAB13
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for RAB13 gene from 5/7 species (see all 7
)
About this table Species with no ortholog for RAB13
ENSEMBL Gene Tree for RAB13 | Paralogs for RAB13(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for RAB13 gene
- RAB1B2 RAB1A2
|
SNPs/Variants for RAB13(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for RAB13 (up to first 250kb)
|
Disorders & Mutations for RAB13
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 602672
|
Medical News for RAB13(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for RAB13 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/20 PubMed articles for RAB13 gene (see all 20
): |
Search for RAB13
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RAB13
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing RAB13
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAB13(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for RAB13(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for RAB13:

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Incremental update: 13 Oct 2009
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