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RAB12 Gene

protein-coding   GIFtS: 45
GCID: GC18P008600

RAB12, Member RAS Oncogene Family

  Search for RAB12
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB12, Member RAS Oncogene Family1 2
Putative Ras-Related Protein Rab-122
Ras-Related Protein Rab-122

External Ids:    HGNC: 313321   Entrez Gene: 2014752   Ensembl: ENSG000002064187   UniProtKB: Q6IQ223   

Export aliases for RAB12 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB12 Gene:
RAB12 (RAB12, member RAS oncogene family) is a protein-coding gene. GO annotations related to this gene include GDP binding and GTP binding. An important paralog of this gene is RAB10.

UniProtKB/Swiss-Prot: RAB12_HUMAN, Q6IQ22
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from
recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010859.15  NC_018929.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB12 gene promoter:
         Egr-3   Egr-1   CUTL1   E47   c-Ets-1   RORalpha1   POU2F1   FOXJ2 (long isoform)   STAT3   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB12 promoter sequence
   Search Chromatin IP Primers for RAB12

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18p11.22   Ensembl cytogenetic band:  18p11.22   HGNC cytogenetic band: 18p11.22

RAB12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB12 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P008600:  view genomic region     (about GC identifiers)

Start:
8,609,443 bp from pter      End:
8,639,380 bp from pter
Size:
29,938 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RAB12_HUMAN, Q6IQ22 (See protein sequence)
Recommended Name: Ras-related protein Rab-12  
Size: 244 amino acids; 27248 Da
Subunit: May interact with RABIF
Sequence caution: Sequence=AAH71600.2; Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=AAH98407.1;
Type=Miscellaneous discrepancy; Note=Intron retention; Sequence=BC050338; Type=Frameshift; Positions=195;
1 PDB 3D structure from and Proteopedia for RAB12:
2IL1 (3D)    
Secondary accessions: A6NEF5 Q4KMQ3

Explore the universe of human proteins at neXtProt for RAB12: NX_Q6IQ22

Explore proteomics data for RAB12 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys172
  • Modification sites at PhosphoSitePlus

  • See RAB12 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001020471.2  
    ENSEMBL proteins: 
     ENSP00000331748  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RAB: RAB, member RAS oncogene

    4 InterPro protein domains:
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase
     IPR003579 Small_GTPase_Rab_type
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q6IQ22

    ProtoNet protein and cluster: Q6IQ22

    UniProtKB/Swiss-Prot: RAB12_HUMAN, Q6IQ22
    Similarity: Belongs to the small GTPase superfamily. Rab family


    Find genes that share domains with RAB12           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RAB12_HUMAN, Q6IQ22
    Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of
    transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active
    GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible
    for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from
    recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor (By
    similarity)
    Enzyme regulation: Rab activation is generally mediated by a guanine exchange factor (GEF), while inactivation
    through hydrolysis of bound GTP is catalyzed by a GTPase activating protein (GAP) (By similarity). That Rab is
    activated by DENND3, a guanine exchange factor

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005525GTP binding IEA--
    GO:0019003GDP binding IDA--
         
    Find genes that share ontologies with RAB12           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RAB12
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    hsa-mir-186-5p (MIRT021142), hsa-mir-148a-3p (MIRT025992), hsa-mir-130b-3p (MIRT020325), hsa-mir-16-5p (MIRT031886)

    Block miRNA regulation of human, mouse, rat RAB12 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RAB12 (see all 28):
    hsa-miR-607 hsa-miR-448 hsa-miR-148b hsa-miR-520d-5p hsa-miR-4272 hsa-miR-106a hsa-miR-29a hsa-miR-29c
    SwitchGear 3'UTR luciferase reporter plasmidRAB12 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB12


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RAB12_HUMAN, Q6IQ22: Recycling endosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Lysosome
    membrane; Lipid-anchor; Cytoplasmic side (By similarity). Golgi apparatus membrane (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    lysosome5
    vacuole5
    cytosol3
    golgi apparatus2
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005622intracellular ----
    GO:0005634nucleus ----
    GO:0005737cytoplasm ----
    GO:0005764lysosome ISS--

    Find genes that share ontologies with RAB12           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB12
    Interactions:

        Search GeneGlobe Interaction Network for RAB12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    Selected Interacting proteins for RAB12 (Q6IQ223 ENSP000003317484) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC64BA1A5D93, ENSP000003739984STRING: ENSP00000373998 I2D: score=1 
    CCDC64Q6ZP653, ENSP000003806904I2D: score=1 STRING: ENSP00000380690
    SLC2A4P146723I2D: score=1 
    YWHABP319463I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
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    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0006913nucleocytoplasmic transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--

    Find genes that share ontologies with RAB12           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RAB12



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB12 gene: 
    NM_001025300.2  

    Unigene Cluster for RAB12:

    RAB12, member RAS oncogene family
    Hs.270074  [show with all ESTs]
    Unigene Representative Sequence: BC071600
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000329286(uc002knp.3) ENST00000580987
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate RAB12 (see all 28):
    hsa-miR-607 hsa-miR-448 hsa-miR-148b hsa-miR-520d-5p hsa-miR-4272 hsa-miR-106a hsa-miR-29a hsa-miR-29c
    SwitchGear 3'UTR luciferase reporter plasmidRAB12 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RAB12
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RAB12 (NM_001025300)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RAB12
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      QuantiFast Probe-based Assays in human, mouse, rat RAB12

    Additional mRNA sequence: 

    AK127824.1 BC050338.1 BC071600.1 BC098407.1 CR627121.1 

    5 DOTS entries:

    DT.97793083  DT.108281  DT.101971256  DT.407758  DT.411259 

    Selected AceView cDNA sequences (see all 53):

    BX493064 BQ024519 CD518316 BX642232 AI356332 BC050338 AA001052 BU754385 
    AI080373 AW449532 R78438 AW452854 N31150 AI076335 BX118866 AA027097 
    CF994415 BF574430 AW452366 CR627121 AA001088 AW449830 BX097121 AA587104 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTCCTAAG
    RAB12 Expression
    About this image

    RAB12 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB12 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.270074
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for RAB12 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab121 , 5 RAB12, member RAS oncogene family1, 5 89.3(n)1
    95.06(a)1
      17 (37.88 cM)5
    193281  NM_024448.21  NP_077768.21 
     664945125 
    chicken
    (Gallus gallus)
    Aves RAB121 RAB12, member RAS oncogene family 87.02(n)
    93.44(a)
      421048  XM_003640800.2  XP_003640848.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB126
    RAB12, member RAS oncogene family
    89(a)
    1 ↔ 1
    GL343319.1(228678-250047)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.129022 Transcribed sequence with weak similarity to protein more 84.97(n)    BX733221.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.150112 Transcribed sequence with weak similarity to protein more 78.24(n)    CK145823.1 
    worm
    (Caenorhabditis elegans)
    Secernentea K02E10.16
    Protein K02E10.1 (K02E10.1) mRNA, complete cds
    32(a)
    1 ↔ 1
    X(2496271-2501001) WBGene00019317
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes YPT16
    Rab family GTPase, involved in the ER-to-Golgi ste...
    42(a)
    1 → many
    VI(55366-55986) YFL038C


    ENSEMBL Gene Tree for RAB12 (if available)
    TreeFam Gene Tree for RAB12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB12 gene
    RAB102  RAB3B2  RAB262  RAB8A2  RAB3D2  RAB372  RAB3A2  RAB8B2  
    RAB1B2  RAB1A2  RAB132  RAB3C2  
    Selected SIMAP similar genes for RAB12 using alignment to 1 protein entry:     RAB12_HUMAN(see all similar genes):
    DKFZp686J06205    rab1b    RAB10    RAB8B    RAB8A    RAB30
    RAB13    RAB3A    RAB19    RAB1C    RAB3B    RAB15
    RAB39B    RAB6A'    RAB41    RAB43    DKFZp686J07132    RAB3C

    Find genes that share paralogs with RAB12           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB12 (see all 684)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1917783821,2
    --8607649(+) ATTCCA/TGAAAA 1 -- us2k10--------
    rs116627851,2
    C,F,A,H--8607757(+) TGCTAG/CAGGAA 1 -- us2k1 trp321Minor allele frequency- C:0.41EA NS NA WA 1172
    rs1504236941,2
    --8607824(+) ATGTTC/TTGCGG 1 -- us2k10--------
    rs1381935841,2
    --8607827(+) TTCTGC/TGGCGG 1 -- us2k10--------
    rs1838601301,2
    --8607831(+) GCGGCA/GGAGCA 1 -- us2k10--------
    rs1891819991,2
    --8607969(+) TTTTTA/TAATTA 1 -- us2k10--------
    rs1496184681,2
    --8608145(+) GAAAGA/GAAAAG 1 -- us2k10--------
    rs1810697671,2
    --8608206(+) TCTGTC/GTTTCA 1 -- us2k10--------
    rs1433202661,2
    C--8608211(+) GTTTCA/TAATAA 1 -- us2k10--------
    rs802049091,2
    C,F--8608231(+) ATCATA/GTTTTA 1 -- us2k11Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for RAB12 (8609443 - 8639380 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RAB12:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2716757CNV Deletion23290073
    esv2656851CNV Deletion23128226
    esv5209CNV Deletion18987735
    esv2716756CNV Deletion23290073
    esv1001194CNV Deletion20482838
    nsv2200CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB12
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB12 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with RAB12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. (PubMed id 23357852)1 Sirohi K....Swarup G. (Autophagy 2013)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    4. Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs). (PubMed id 22178446)1 Lopitz-Otsoa F....Rodriguez M.S. (J Proteomics 2012)
    5. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Identification and characterisation of novel Mss4-binding Rab GTPases. (PubMed id 21194374)2 Wixler V.... Itzen A. (Biol. Chem. 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 201475 HGNC: 31332 AceView: LOC201475 Ensembl:ENSG00000206418 euGenes: HUgn201475
    ECgene: RAB12 H-InvDB: RAB12

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB12 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for RAB12 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB12 gene:
    Search GeneIP for patents involving RAB12

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