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RAB11FIP5 Gene

protein-coding   GIFtS: 60
GCID: GC02M073212

RAB11 Family Interacting Protein 5 (Class I)

  See RAB11FIP5-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB11 Family Interacting Protein 5 (Class I)1 2     gaf-12
RIP112 3 5     pp752
Gamma-SNAP-Associated Factor 12 3     Rab11 Family-Interacting Protein 52
Phosphoprotein Pp752 3     rab11-FIP52
Rab11-Interacting Protein Rip112 3     Gaf-13
GAF12 3     Rab11-FIP53
KIAA08573 5     RAB11RIP55

External Ids:    HGNC: 248451   Entrez Gene: 260562   Ensembl: ENSG000001356317   OMIM: 6055365   UniProtKB: Q9BXF63   

Export aliases for RAB11FIP5 gene to outside databases

Previous GC identifer: GC02M073036


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RAB11FIP5 Gene:
RAB11FIP5 (RAB11 family interacting protein 5 (class I)) is a protein-coding gene. Diseases associated with RAB11FIP5 include atypical autism. GO annotations related to this gene include gamma-tubulin binding. An important paralog of this gene is RAB11FIP1.

UniProtKB/Swiss-Prot: RFIP5_HUMAN, Q9BXF6
Function: Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma
membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to
extracellular acidosis

Gene Wiki entry for RAB11FIP5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_022184.16  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB11FIP5 gene promoter:
         SRF   SRF (504 AA)   AP-2gamma   MEF-2A   PPAR-gamma1   AP-2beta   aMEF-2   PPAR-gamma2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB11FIP5 promoter sequence
   Search Chromatin IP Primers for RAB11FIP5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB11FIP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p13   Ensembl cytogenetic band:  2p13.2   HGNC cytogenetic band: 2p13

RAB11FIP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB11FIP5 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M073212:  view genomic region     (about GC identifiers)

Start:
73,300,510 bp from pter      End:
73,383,849 bp from pter
Size:
83,340 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RFIP5_HUMAN, Q9BXF6 (See protein sequence)
Recommended Name: Rab11 family-interacting protein 5  
Size: 653 amino acids; 70415 Da
Subunit: Forms a heterooligomeric complex with RAB11FIP4. Binds NAPG and TROVE2. Binds RAB11A that has been
activated by GTP binding
Miscellaneous: Antibodies against RIP11 are found in sera from patients with autoimmune diseases such as systemic
lupus erythematosus (SLE) or Sjoegren syndrome (SS). It is also found in the sera from mothers of children with
neonatal lupus erythematosus (NLE)
Sequence caution: Sequence=BAA74880.1; Type=Erroneous initiation;
Secondary accessions: O94939 Q9P0M1

Explore the universe of human proteins at neXtProt for RAB11FIP5: NX_Q9BXF6

Explore proteomics data for RAB11FIP5 at MOPED

Post-translational modifications: 

  • Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent1
  • Ubiquitination2 at Lys586
  • Modification sites at PhosphoSitePlus

  • See RAB11FIP5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056285.1  
    ENSEMBL proteins: 
     ENSP00000258098  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR019018 Rab-bd_FIP-RBD
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry Q9BXF6

    ProtoNet protein and cluster: Q9BXF6

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: RFIP5_HUMAN, Q9BXF6
    Domain: Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by
    Mg(2+) rather than Ca(2+)
    Similarity: Contains 1 C2 domain
    Similarity: Contains 1 FIP-RBD domain


    Find genes that share domains with RAB11FIP5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RFIP5_HUMAN, Q9BXF6
    Function: Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma
    membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to
    extracellular acidosis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI11278501
    GO:0043015gamma-tubulin binding IDA11278501
         
    Find genes that share ontologies with RAB11FIP5           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB11FIP5:
     Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RAB11FIP5

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    hsa-miR-142-5p hsa-miR-520e hsa-miR-302d hsa-miR-106a hsa-miR-15a hsa-miR-486-3p hsa-miR-650 hsa-miR-548l
    SwitchGear 3'UTR luciferase reporter plasmidRAB11FIP5 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RFIP5_HUMAN, Q9BXF6: Cytoplasm. Recycling endosome membrane; Peripheral membrane protein. Early endosome
    membrane; Peripheral membrane protein (By similarity). Golgi apparatus membrane; Peripheral membrane protein (By
    similarity). Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein (By similarity).
    Mitochondrion membrane; Peripheral membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    mitochondrion5
    cytoskeleton4
    cytosol2
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005739mitochondrion ----
    GO:0005741mitochondrial outer membrane IDA11278501
    GO:0005769early endosome ISS--
    GO:0005794Golgi apparatus ISS--

    Find genes that share ontologies with RAB11FIP5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB11FIP5 About    
    See pathways by source

    SuperPathContained pathways About
    1Clathrin dependent protein traffic
    Transport Clathrin coated vesicle cycle0.66
    2Endocytosis
    Endocytosis


    Find genes that share SuperPaths with RAB11FIP5           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for RAB11FIP5
        Transport Clathrin-coated vesicle cycle


    1 Kegg Pathway  (Kegg details for RAB11FIP5):
        Endocytosis

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB11FIP5
    Interactions:

        GeneGlobe Interaction Network for RAB11FIP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for RAB11FIP5 (Q9BXF63 ENSP000002580984) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB11BQ159073, ENSP000003335474I2D: score=3 STRING: ENSP00000333547
    SMAD3P840223, ENSP000003329734I2D: score=2 STRING: ENSP00000332973
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    RAB11AP624913, ENSP000002618904I2D: score=4 STRING: ENSP00000261890
    RAB25P577353, ENSP000003543764I2D: score=2 STRING: ENSP00000354376
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015031protein transport IEA--
    GO:0035773insulin secretion involved in cellular response to glucose stimulus ISS--
    GO:0045055regulated secretory pathway ISS--
    GO:0071468cellular response to acidity IDA--
    GO:2000008regulation of protein localization to cell surface IMP--

    Find genes that share ontologies with RAB11FIP5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RAB11FIP5 (RFIP5)

    1 HMDB Compound for RAB11FIP5    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB11FIP5 gene: 
    NM_015470.2  

    Unigene Cluster for RAB11FIP5:

    RAB11 family interacting protein 5 (class I)
    Hs.24557  [show with all ESTs]
    Unigene Representative Sequence: NM_015470
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486777(uc002sis.4) ENST00000258098(uc002siu.4) ENST00000482554
    ENST00000493523(uc002sit.4) ENST00000479196 ENST00000475951
    miRNA
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    hsa-miR-142-5p hsa-miR-520e hsa-miR-302d hsa-miR-106a hsa-miR-15a hsa-miR-486-3p hsa-miR-650 hsa-miR-548l
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    Additional mRNA sequence: 

    AB020664.1 AF153085.1 AF334812.1 AK023823.1 AK024727.1 AL117579.1 BC035013.1 BC099902.1 

    6 DOTS entries:

    DT.95193266  DT.100786167  DT.100786169  DT.120982464  DT.120982480  DT.80100253 

    Selected AceView cDNA sequences (see all 367):

    AU122562 AA351734 CA416568 AI657161 BQ669364 AK094205 CA313291 BE549871 
    BM985431 AI569265 BE856280 BE889893 AA909346 AI419508 BU196335 BU528165 
    AL117579 BU856868 Z45690 BC013233 BQ006184 BU541928 CR614772 AI358847 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RAB11FIP5 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b
    SP1:        -                                   -     -     -                           
    SP2:                                            -     -     -                           
    SP3:                    -     -     -           -     -     -                           
    SP4:                                                  -     -                           
    SP5:                                                                                    


    ECgene alternative splicing isoforms for RAB11FIP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB11FIP5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    RAB11FIP5 Expression
    About this image


    RAB11FIP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebellum
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass
     
     Testis (Reproductive System)
    RAB11FIP5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB11FIP5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.24557

    UniProtKB/Swiss-Prot: RFIP5_HUMAN, Q9BXF6
    Tissue specificity: Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen,
    skeletal muscle and pancreas

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB11FIP5 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab11fip51 , 5 RAB11 family interacting protein 5 (class I)1, 5 84.38(n)1
    85.74(a)1
      6 (37.35 cM)5
    520551  NM_001003955.21  NP_001003955.11 
     853349635 
    chicken
    (Gallus gallus)
    Aves RAB11FIP56
    RAB11 family interacting protein 5 (class I)
    26(a)
    1 ↔ 1
    4(89260772-89283484)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.183552 Xenopus laevis transcribed sequence with weak similarity more 75.28(n)    CA792603.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab11fip5a6
    RAB11FIP5 (1 of 2)6
    RAB11 family interacting protein 5 (class I)
    34(a)
    17(a)
    1 ↔ many
    1 ↔ many
    13(14952269-15096108) ENSDARG00000094510
    14(48198488-48238780) ENSDARG00000088248
    fruit fly
    (Drosophila melanogaster)
    Insecta Rip116
    Rab11 interacting protein
    13(a)
    1 → many
    X(18529675-18541596)


    ENSEMBL Gene Tree for RAB11FIP5 (if available)
    TreeFam Gene Tree for RAB11FIP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB11FIP5 gene
    RAB11FIP12  RAB11FIP22  
    3 SIMAP similar genes for RAB11FIP5 using alignment to 1 protein entry:     RFIP5_HUMAN:
    GAF1    DKFZp434H018    RAB11FIP1

    Find genes that share paralogs with RAB11FIP5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB11FIP5 (see all 802)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1167532231,2
    C,F--73207254(+) GGCCCA/GGTCCT 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1169148991,2
    C,F--73300974(+) TCTGCT/CCCATC 1 -- ut311Minor allele frequency- C:0.02EA 120
    rs1446651201,2
    --73301064(+) AAGAAA/GTGGTG 1 -- ut310--------
    rs764770101,2
    C,F--73301104(+) AGCTGT/CTAAGT 1 -- ut311Minor allele frequency- C:0.04WA 118
    rs98084771,2
    C,F--73301181(+) CCCTGC/TAGATG 1 -- ut31 ese32Minor allele frequency- T:0.17NA WA 120
    rs1485388811,2
    --73301261(+) CAAAGC/TGCACT 1 -- ut310--------
    rs1428640371,2
    --73301292(+) CCTGGA/GGCAGA 1 -- ut310--------
    rs1510978841,2
    --73301318(+) TAGCAA/GCTTAA 1 -- ut310--------
    rs1848538911,2
    --73301331(+) GATGGA/GTGGGA 1 -- ut310--------
    rs1889337791,2
    --73301432(+) CTAAGC/TCCTGA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RAB11FIP5 (73300510 - 73383849 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for RAB11FIP5: --
    Human Gene Mutation Database (HGMD): RAB11FIP5
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB11FIP5
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB11FIP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605536    OMIM disorders: --

    1 disease for RAB11FIP5:    
    About MalaCards
    atypical autism

    1 disease from the University of Copenhagen DISEASES database for RAB11FIP5:
    Atypical autism

    Find genes that share disorders with RAB11FIP5           About GenesLikeMe

    Genetic Association Database (GAD): RAB11FIP5
    Human Genome Epidemiology (HuGE) Navigator: RAB11FIP5 (2 documents)

    Export disorders for RAB11FIP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB11FIP5 gene, integrated from 10 sources (see all 50):
    (articles sorted by number of sources associating them with RAB11FIP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes. (PubMed id 11163216)1, 2, 3 Prekeris R.... Scheller R.H. (Mol. Cell 2000)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    3. Gaf-1, a gamma-SNAP-binding protein associated with the mitochondria. (PubMed id 11278501)1, 2, 9 Chen D.... Whiteheart S.W. (J. Biol. Chem. 2001)
    4. Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies. (PubMed id 10545525)1, 2, 9 Wang D.... Chan E.K.L. (J. Clin. Invest. 1999)
    5. Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells. (PubMed id 12470645)1, 2, 9 Wallace D.M.... McCaffrey M.W. (Biochem. Biophys. Res. Commun. 2002)
    6. Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts. (PubMed id 20717956)1, 2 Oehlke O....Roussa E. (J. Cell. Physiol. 2011)
    7. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    9. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26056 HGNC: 24845 AceView: RAB11FIP5andSFXN5 Ensembl:ENSG00000135631 euGenes: HUgn26056
    ECgene: RAB11FIP5 Kegg: 26056 H-InvDB: RAB11FIP5

    (According to HUGE)
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    HUGE: KIAA0857

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB11FIP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB11FIP5 gene:
    Search GeneIP for patents involving RAB11FIP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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