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RAB11FIP4 Gene

protein-coding   GIFtS: 56
GCID: GC17P029718

RAB11 Family Interacting Protein 4 (Class II)

  Search for RAB11FIP4
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
RAB11 Family Interacting Protein 4 (Class II)1 2     Rab11 Family-Interacting Protein 42
FIP4-Rab112 3     ARFO23
KIAA18213 5     Arfophilin-23
RAB11-FIP42     Rab11-FIP43
arfophilin-22     

External Ids:    HGNC: 302671   Entrez Gene: 844402   Ensembl: ENSG000001312427   OMIM: 6119995   UniProtKB: Q86YS33   

Export aliases for RAB11FIP4 gene to outside databases

Previous GC identifers: GC17P026742 GC17P025912


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for RAB11FIP4 Gene:
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting,
and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate
Rab GTPases (Hales et al., 2001 (PubMed 11495908)).(supplied by OMIM, Apr 2008)

GeneCards Summary for RAB11FIP4 Gene:
RAB11FIP4 (RAB11 family interacting protein 4 (class II)) is a protein-coding gene. GO annotations related to this gene include Rab GTPase binding and calcium ion binding. An important paralog of this gene is RAB11FIP3.

UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
Function: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the
abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to
the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may
participate in egress of the virus out of nucleus; this function is independent of ARF6

Gene Wiki entry for RAB11FIP4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RAB11FIP4 gene promoter:
         HOXA9B   HOXA9   MEF-2A   MEF-2   NRSF form 1   aMEF-2   NRSF form 2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB11FIP4 promoter sequence
   Search Chromatin IP Primers for RAB11FIP4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RAB11FIP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

RAB11FIP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB11FIP4 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P029718:  view genomic region     (about GC identifiers)

Start:
29,718,642 bp from pter      End:
29,865,236 bp from pter
Size:
146,595 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3 (See protein sequence)
Recommended Name: Rab11 family-interacting protein 4  
Size: 637 amino acids; 71928 Da
Subunit: Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction
is direct. Forms a heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with HCMV (human
cytomegalovirus) gM/UL100. Interacts with ECM29
Secondary accessions: Q52LI1 Q8N829 Q8NDT7 Q969D8
Alternative splicing: 2 isoforms:  Q86YS3-1   Q86YS3-2   

Explore the universe of human proteins at neXtProt for RAB11FIP4: NX_Q86YS3

Explore proteomics data for RAB11FIP4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RAB11FIP4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116321.2  
    ENSEMBL proteins: 
     ENSP00000312837   ENSP00000463206   ENSP00000378227   ENSP00000465929   ENSP00000466538  
     ENSP00000463616  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    EFHAND: EF-hand domain containing

    3 InterPro protein domains:
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR019018 Rab-bd_FIP-RBD

    Graphical View of Domain Structure for InterPro Entry Q86YS3

    ProtoNet protein and cluster: Q86YS3

    UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
    Domain: The RBD-FIP domain mediates the interaction with Rab11 (RAB11A or RAB11B) (By similarity)
    Similarity: Contains 1 EF-hand domain
    Similarity: Contains 1 FIP-RBD domain


    Find genes that share domains with RAB11FIP4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RFIP4_HUMAN, Q86YS3
    Function: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the
    abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to
    the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may
    participate in egress of the virus out of nucleus; this function is independent of ARF6

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding IPI12470645
    GO:0017137Rab GTPase binding IPI12470645
    GO:0030306ADP-ribosylation factor binding IPI16148947
    GO:0042803protein homodimerization activity IDA12470645
         
    Find genes that share ontologies with RAB11FIP4           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB11FIP4:
     Increased HPV18 LCR reporter a 

    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RFIP4_HUMAN, Q86YS3: Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody.
    Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    cytosol2
    nucleus2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0005768endosome IDA--
    GO:0030139endocytic vesicle IDA--
    GO:0030496midbody IDA15601896
    GO:0032154cleavage furrow IDA15601896

    Find genes that share ontologies with RAB11FIP4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for RAB11FIP4 About    
    See pathways by source

    SuperPathContained pathways About
    1Endocytosis
    Endocytosis


    Find genes that share SuperPaths with RAB11FIP4           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for RAB11FIP4):
        Endocytosis

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RAB11FIP4
    Interactions:

        Search GeneGlobe Interaction Network for RAB11FIP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for RAB11FIP4 (Q86YS31, 2, 3 ENSP000003128374) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GFI1BQ5VTD92, 3, ENSP000003447824MINT-2877104 I2D: score=3 STRING: ENSP00000344782
    RACGAP1Q9H0H52, 3, ENSP000003098714MINT-6799611 I2D: score=1 STRING: ENSP00000309871
    RAB11AP624913, ENSP000002618904I2D: score=2 STRING: ENSP00000261890
    RAB11FIP3O751543, ENSP000002623054I2D: score=2 STRING: ENSP00000262305
    RAB11FIP5Q9BXF63, ENSP000002580984I2D: score=2 STRING: ENSP00000258098
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis IMP16148947
    GO:0006810transport IEA--
    GO:0016032viral process IEA--
    GO:0019048modulation by virus of host morphology or physiology ----

    Find genes that share ontologies with RAB11FIP4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RAB11FIP4 (RFIP4)

    1 HMDB Compound for RAB11FIP4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RAB11FIP4 gene: 
    NM_032932.3  

    Unigene Cluster for RAB11FIP4:

    RAB11 family interacting protein 4 (class II)
    Hs.406788  [show with all ESTs]
    Unigene Representative Sequence: NM_032932
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000325874(uc002hgn.1 uc002hgo.2) ENST00000581280 ENST00000582009
    ENST00000579908 ENST00000394744 ENST00000583755 ENST00000579589 ENST00000578694
    ENST00000585058 ENST00000581460 ENST00000578148
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    hsa-miR-194* hsa-miR-3194-5p hsa-miR-106a hsa-miR-519a hsa-miR-877* hsa-miR-629* hsa-miR-93 hsa-miR-34c-5p
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      QuantiTect SYBR Green Assays in human, mouse, rat RAB11FIP4
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    Additional mRNA sequence: 

    AB058724.1 AJ314646.2 AK055019.1 AK074060.1 AK074341.1 AK097424.1 AL359563.2 AL831830.1 
    AY169244.1 BC004515.2 BC006240.2 BC023618.2 BC047674.2 BC093914.1 BC094803.1 BC101517.1 
    BC131530.1 

    17 DOTS entries:

    DT.114031  DT.95170396  DT.101972169  DT.99935414  DT.100024384  DT.100690178  DT.216144  DT.100758122 
    DT.97822631  DT.97813902  DT.120973045  DT.91740632  DT.120972500  DT.120972755  DT.95170395  DT.120972576 
    DT.91845606 

    Selected AceView cDNA sequences (see all 258):

    BE746924 BM792410 BQ188378 AA458869 BE743232 BC047674 AI937421 AW083393 
    BF035341 Z39098 NM_032932 BF064276 AB058724 AA279012 BE501304 AA829491 
    AA563715 F06254 F12210 AL120133 Z39531 AA864726 AY169244 F02539 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RAB11FIP4 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^
    SP1:                                                                                                                                                            
    SP2:              -     -                       -     -     -                                                                                                   
    SP3:                                            -     -     -                                                                                                   
    SP4:                                                                                                                                                            
    SP5:                                            -     -     -                                                                                                   

    ExUns: 18 ^ 19
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for RAB11FIP4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RAB11FIP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTACTTACCT
    RAB11FIP4 Expression
    About this image


    RAB11FIP4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Thymus (Hematopoietic System)
             Thymus
     
     Bone (Muscoskeletal System)
             Endochondral Facial Bones
     
     Cartilage (Muscoskeletal System)
             Meckel's Cartilage
    RAB11FIP4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RAB11FIP4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.406788

    UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
    Tissue specificity: Present at high level in testis (at protein level). Weakly expressed in other tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for RAB11FIP4 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab11fip41 , 5 RAB11 family interacting protein 4 (class II)1, 5 87.96(n)1
    93.22(a)1
      11 (46.88 cM)5
    2684511  NM_175543.31  NP_780752.11 
     795912125 
    chicken
    (Gallus gallus)
    Aves RAB11FIP41 RAB11 family interacting protein 4 (class II) 72.76(n)
    80.61(a)
      427808  XM_425379.4  XP_425379.3 
    lizard
    (Anolis carolinensis)
    Reptilia RAB11FIP46
    RAB11 family interacting protein 4 (class II)
    76(a)
    1 ↔ 1
    GL343198.1(760986-976295)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rab11fip41 RAB11 family interacting protein 4 (class II) 70.93(n)
    69.65(a)
      100124715  NM_001102700.1  NP_001096170.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rab11fip4a1 RAB11 family interacting protein 4 (class II) a 69.42(n)
    71.74(a)
      436806  NM_001002533.2  NP_001002533.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta nuf6
    nuclear fallout
    21(a)
    1 → many
    3L(14183970-14226350)
    worm
    (Caenorhabditis elegans)
    Secernentea F55C12.16
    Protein F55C12.1, isoform a (F55C12.1) mRNA, compl...
    21(a)
    1 → many
    II(5884552-5892675) WBGene00018869


    ENSEMBL Gene Tree for RAB11FIP4 (if available)
    TreeFam Gene Tree for RAB11FIP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RAB11FIP4 gene
    RAB11FIP32  
    1 SIMAP similar gene for RAB11FIP4 using alignment to 6 protein entries:     RFIP4_HUMAN (see all proteins):
    RAB11FIP3

    Find genes that share paralogs with RAB11FIP4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RAB11FIP4 (see all 3344)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1161307321,2
    C,Funtested129850608(+) TCTTGC/TGACAA 2 C syn12Minor allele frequency- T:0.00WA NA 4670
    rs1440825681,2
    --25915729(+) CAGGTA/GATAGA 1 -- int10--------
    rs47956001,2
    H--25915795(+) GGGTTC/ACtcac 1 -- int14Minor allele frequency- A:0.00NS EA 408
    rs47956021,2
    H--25915829(+) GTCCTC/AATCCT 1 -- int14Minor allele frequency- A:0.00NS EA 404
    rs1464802201,2
    --25915889(+) AGAGTA/GTGTGT 1 -- int10--------
    rs1410460531,2
    C--25915958(+) GAACTA/GAAAAC 1 -- int10--------
    rs1828136261,2
    --25916040(+) GGATAC/GTGACC 1 -- int10--------
    rs1878926871,2
    --25916046(+) TGACCC/TTCTAG 1 -- int10--------
    rs1909746591,2
    --25916099(+) TGGGCA/GACTTA 1 -- int10--------
    rs99122991,2
    C,F,H--25916156(+) GGGACA/CCCCTT 1 -- int14Minor allele frequency- C:0.00NS EA 412

    HapMap Linkage Disequilibrium report for RAB11FIP4 (29718642 - 29865236 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RAB11FIP4 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2715819CNV Deletion23290073
    esv2536682CNV Deletion19546169
    esv2678438CNV Deletion23128226
    esv270287CNV Insertion20981092
    nsv522350CNV Loss19592680
    esv28654CNV Loss19812545
    nsv111881CNV Loss16902084
    nsv519930CNV Loss19592680
    nsv827947CNV Gain20364138
    nsv827946CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RAB11FIP4
    DNA2.0 Custom Variant and Variant Library Synthesis for RAB11FIP4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611999    OMIM disorders: --


    Find genes that share disorders with RAB11FIP4           About GenesLikeMe

    Genetic Association Database (GAD): RAB11FIP4
    Human Genome Epidemiology (HuGE) Navigator: RAB11FIP4 (1 document)

    Export disorders for RAB11FIP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RAB11FIP4 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with RAB11FIP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2001)
    2. Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse. (PubMed id 12696059)1, 2, 9 Jenne D.E....Kehrer-Sawatzki H. (Genes Chromosomes Cancer 2003)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. (PubMed id 20682791)1, 2 Gorbea C.... Rechsteiner M. (J. Biol. Chem. 2010)
    5. The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. (PubMed id 15601896)1, 2 Wilson G.M.... Prekeris R. (Mol. Biol. Cell 2005)
    6. Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis. (PubMed id 16148947)1, 2 Fielding A.B.... Gould G.W. (EMBO J. 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells. (PubMed id 12470645)1, 2 Wallace D.M.... McCaffrey M.W. (Biochem. Biophys. Res. Commun. 2002)
    10. Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions. (PubMed id 11468690)1, 3 Jenne D.E.... Kehrer-Sawatzki H. (Am. J. Hum. Genet. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84440 HGNC: 30267 AceView: RAB11FIP4 Ensembl:ENSG00000131242 euGenes: HUgn84440
    ECgene: RAB11FIP4 Kegg: 84440 H-InvDB: RAB11FIP4

    (According to HUGE)
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    HUGE: KIAA1821

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RAB11FIP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RAB11FIP4 gene:
    Search GeneIP for patents involving RAB11FIP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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