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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB11FIP4 Gene

protein-coding   GIFtS: 57
GCID: GC17P029718

RAB11 family interacting protein 4 (class II)

 Explore 5 diseases affiliated with
RAB11FIP4 via our new
 Human Malady Compendium 
Biological research products
for RAB11FIP4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
RAB11 Family Interacting Protein 4 (Class II)1 2     Arfophilin-23
KIAA18211 3 5     Rab11 Family-Interacting Protein 42
RAB11-FIP41 2     ARFO23
FIP4-Rab112 3     Arfophilin-23
FLJ001311     Rab11-FIP43
MGC113161     

External Ids:    HGNC: 302671   Entrez Gene: 844402   Ensembl: ENSG000001312427   OMIM: 6119995   UniProtKB: Q86YS33   

Export aliases for RAB11FIP4 gene to outside databases

Previous GC identifers: GC17P026742 GC17P025912


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RAB11FIP4:
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and
fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab
GTPases (Hales et al., 2001 (PubMed 11495908)).(supplied by OMIM, Apr 2008)

UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
Function: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission
step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage
furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the
virus out of nucleus; this function is independent of ARF6

Gene Wiki entry for RAB11FIP4


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010799.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB11FIP4 gene promoter:
         HOXA9B   HOXA9   MEF-2A   MEF-2   NRSF form 1   aMEF-2   NRSF form 2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RAB11FIP4 promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB11FIP4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB11FIP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q11.2   Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

RAB11FIP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB11FIP4 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P029718:  view genomic region     (about GC identifiers)

Start:
29,718,642 bp from pter      End:
29,865,236 bp from pter
Size:
146,595 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3 (See protein sequence)
Recommended Name: Rab11 family-interacting protein 4  
Size: 637 amino acids; 71928 Da
Subunit: Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is
direct. Forms a heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with HCMV (human
cytomegalovirus) gM/UL100. Interacts with ECM29
Subcellular location: Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic
vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis
Secondary accessions: Q52LI1 Q8N829 Q8NDT7 Q969D8
Alternative splicing: 2 isoforms:  Q86YS3-1   Q86YS3-2   

Explore the universe of human proteins at neXtProt for RAB11FIP4: NX_Q86YS3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q86YS3

  • RAB11FIP4 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_116321.2  
    ENSEMBL proteins: 
     ENSP00000312837   ENSP00000463206   ENSP00000378227   ENSP00000465929   ENSP00000466538  
     ENSP00000463616  

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    Uscn Proteins for RAB11FIP4

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005768endosome IDA--
    GO:0030139endocytic vesicle IDA--
    GO:0030496midbody IDA16148947
    GO:0032154cleavage furrow IDA15601896
    GO:0055038recycling endosome membrane IDA12470645


    RAB11FIP4 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RAB11FIP4 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR019018 Rab-bd_FIP-RBD

    Graphical View of Domain Structure for InterPro Entry Q86YS3

    ProtoNet protein and cluster: Q86YS3

    UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
    Domain: The RBD-FIP domain mediates the interaction with Rab11 (RAB11A or RAB11B) (By similarity)
    Similarity: Contains 1 EF-hand domain
    Similarity: Contains 1 FIP-RBD domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
    Function: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission
    step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage
    furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the
    virus out of nucleus; this function is independent of ARF6

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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding IPI16148947
    GO:0017137Rab GTPase binding IPI16148947
    GO:0030306ADP-ribosylation factor binding IPI16148947
    GO:0042803protein homodimerization activity IDA12470645


    RAB11FIP4 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for RAB11FIP4:
     Increased HPV18 LCR reporter a 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Endocytosis
    Endocytosis1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for RAB11FIP4):
        Endocytosis


    RAB11FIP4 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RAB11FIP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/12 Interacting proteins for RAB11FIP4 (Q86YS32, 3 ENSP000003128374) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GFI1BQ5VTD92, 3, ENSP000003447824MINT-2877104 I2D: score=3 STRING: ENSP00000344782
    RACGAP1Q9H0H52, 3, ENSP000003098714MINT-6799611 I2D: score=1 STRING: ENSP00000309871
    RAB11AP624913, ENSP000002618904I2D: score=2 STRING: ENSP00000261890
    RAB11FIP3O751543, ENSP000002623054I2D: score=2 STRING: ENSP00000262305
    RAB11FIP5Q9BXF63, ENSP000002580984I2D: score=2 STRING: ENSP00000258098
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis IMP16148947
    GO:0006810transport IEA--
    GO:0019048virus-host interaction IEA--
    GO:0044419interspecies interaction between organisms ----


    RAB11FIP4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RAB11FIP4

    1 HMDB Compound for RAB11FIP4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Search CenterWatch for drugs/clinical trials and news about RAB11FIP4 / RFIP4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB11FIP4 gene: 
    NM_032932.3  

    Unigene Cluster for RAB11FIP4:

    RAB11 family interacting protein 4 (class II)
    Hs.406788  [show with all ESTs]
    Unigene Representative Sequence: NM_032932
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000325874(uc002hgn.1 uc002hgo.2) ENST00000581280 ENST00000582009
    ENST00000579908 ENST00000394744 ENST00000583755 ENST00000579589 ENST00000578694
    ENST00000585058 ENST00000581460 ENST00000578148

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    hsa-miR-194* hsa-miR-3194-5p hsa-miR-106a hsa-miR-519a hsa-miR-877* hsa-miR-629* hsa-miR-93 hsa-miR-34c-5p
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    Additional cDNA sequence: 

    AB058724.1 AJ314646.2 AK055019.1 AK074060.1 AK074341.1 AK097424.1 AL359563.2 AL831830.1 
    AY169244.1 BC004515.2 BC006240.2 BC023618.2 BC047674.2 BC093914.1 BC094803.1 BC101517.1 
    BC131530.1 

    17 DOTS entries:

    DT.114031  DT.95170396  DT.101972169  DT.99935414  DT.100024384  DT.100690178  DT.216144  DT.100758122 
    DT.97822631  DT.97813902  DT.120973045  DT.91740632  DT.120972500  DT.120972755  DT.95170395  DT.120972576 
    DT.91845606 

    24/258 AceView cDNA sequences (see all 258):

    AI937421 BQ188378 BM792410 BF035341 AA563715 AA829491 F12210 F06254 
    AL120133 AA864726 Z39531 AY169244 F02539 BM982404 BC006240 AL521106 
    T33386 AW751140 AI378388 BX480302 BQ889990 BE392773 AL831830 Z42981 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for RAB11FIP4 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^
    SP1:                                                                                                                                                            
    SP2:              -     -                       -     -     -                                                                                                   
    SP3:                                            -     -     -                                                                                                   
    SP4:                                                                                                                                                            
    SP5:                                            -     -     -                                                                                                   

    ExUns: 18 ^ 19
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for RAB11FIP4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB11FIP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTACTTACCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    RAB11FIP4 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TrophoblastMural TrophectodermMural Trophectoderm CellsExtraembryonic Tissues
    BoneEndochondral Facial BonesBone
    CartilageMeckel's CartilageCartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass

    See RAB11FIP4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB11FIP4

    SOURCE GeneReport for Unigene cluster: Hs.406788

    UniProtKB/Swiss-Prot: RFIP4_HUMAN, Q86YS3
    Tissue specificity: Present at high level in testis (at protein level). Weakly expressed in other tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RAB11FIP4 gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves RAB11FIP41 RAB11 family interacting protein 4 (class II) 72.76(n)
    80.61(a)
      427808  XM_425379.3  XP_425379.3 
    lizard
    (Anolis carolinensis)
    Reptilia RAB11FIP46
    --
    74(a)
    1 ↔ 1
    GL343198.1(955917-976295)
    zebrafish
    (Danio rerio)
    Actinopterygii rab11fip4a1 RAB11 family interacting protein 4 (class II) a 69.53(n)
    71.74(a)
      436806  NM_001002533.2  NP_001002533.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta nuf6
    nuclear fallout
    20(a)
    1 → many
    3L(14183970-14226350)
    worm
    (Caenorhabditis elegans)
    Secernentea F55C12.11 Protein F55C12.1 41.41(n)
    30.61(a)
      173998  NM_062774.2  NP_495175.1 


    ENSEMBL Gene Tree for RAB11FIP4 (if available)
    TreeFam Gene Tree for RAB11FIP4 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB11FIP4 gene
    RAB11FIP32  
    1 SIMAP similar gene for RAB11FIP4 using alignment to 6 protein entries:     RFIP4_HUMAN (see all proteins):
    RAB11FIP3

    RAB11FIP4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2638 NCBI SNPs in RAB11FIP4 are shown (see all 2638    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs47956001,2
    H--25915795(+) GGGTTC/ACtcac 1 -- int14Minor allele frequency- A:0.00NS EA 408
    rs47956021,2
    H--25915829(+) GTCCTC/AATCCT 1 -- int14Minor allele frequency- A:0.00NS EA 404
    rs99122991,2
    C,H,--25916156(+) GGGACA/CCCCTT 1 -- int14Minor allele frequency- C:0.00NS EA 412
    rs744796881,2
    --25916334(+) AGCCCC/TTAGTG 1 -- int11Minor allele frequency- T:0.01NA 120
    rs1131863931,2
    --25916619(+) CCAGCC/TGGGCG 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs2008499341,2
    C--25916910(-) GTTCTA/TTTTTT 1 -- int10--------
    rs671794311,2
    C--26055745(+) GTCTC-/AAAAAA 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1129597211,2
    --29719295(+) CGGCCA/GTGCAG 1 -- int13Minor allele frequency- G:0.15CSA WA 121
    rs1405296571,2
    --29719439(+) GCCAGG/TGGGTG 1 -- int10--------
    rs786907101,2
    F,--29719717(+) TAGATT/GGTTAA 1 -- int11Minor allele frequency- G:0.02EA 120

    HapMap Linkage Disequilibrium report for RAB11FIP4 (29718642 - 29865236 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 10 variations for RAB11FIP4
         3 CNVs: 4999 102438 5860
         7 Indels: 67174 77570 77571 40177 88420 88419 49837

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RAB11FIP4 for disorders           About GeneDecksing

    OMIM gene information: 611999    OMIM disorders: --

    5 diseases for RAB11FIP4:    About MalaCards
    retinal detachment    myopia    neurofibromatosis    retinitis
    ataxia

    Human Genome Epidemiology (HuGE) Navigator: RAB11FIP4 (1 document)

    Export disorders for RAB11FIP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB11FIP4 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with RAB11FIP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (2001)
    2. Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse. (PubMed id 12696059)1, 2, 9 Jenne D.E....Kehrer-Sawatzki H. (2003)
    3. A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components. (PubMed id 20682791)1, 2 Gorbea C.... Rechsteiner M. (2010)
    4. The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. (PubMed id 15601896)1, 2 Wilson G.M....Prekeris R. (2005)
    5. Rab11-FIP3 and FIP4 interact with Arf6 and the exocyst to control membrane traffic in cytokinesis. (PubMed id 16148947)1, 2 Fielding A.B.... Gould G.W. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Rab11-FIP4 interacts with Rab11 in a GTP-dependent manner and its overexpression condenses the Rab11 positive compartment in HeLa cells. (PubMed id 12470645)1, 2 Wallace D.M.... McCaffrey M.W. (2002)
    9. Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions. (PubMed id 11468690)1, 3 Jenne D.E....Kehrer-Sawatzki H. (2001)
    10. Tumor susceptibility gene 101 (TSG101) is a novel bind ing-partner for the class II Rab11-FIPs. (PubMed id 22348143)1 Horgan C.P....McCaffrey M.W. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84440 HGNC: 30267 AceView: RAB11FIP4 Ensembl:ENSG00000131242 euGenes: HUgn84440
    ECgene: RAB11FIP4 Kegg: 84440 H-InvDB: RAB11FIP4

    (According to HUGE)
    About This Section
    HUGE: KIAA1821

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB11FIP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB11FIP4 gene:
    Search GeneIP for patents involving RAB11FIP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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