Aliases for RAB11FIP3 Gene
Aliases for RAB11FIP3 Gene
External Ids for RAB11FIP3 Gene
- HGNC: 17224
- Entrez Gene: 9727
- Ensembl: ENSG00000090565
- OMIM: 608738
- UniProtKB: O75154
Previous GeneCards Identifiers for RAB11FIP3 Gene
- GC16P000416
- GC16P000475
- GC16P000394
Summaries for RAB11FIP3 Gene
-
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RAB11FIP3 Gene
RAB11FIP3 (RAB11 Family Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Organelle biogenesis and maintenance and Cargo trafficking to the periciliary membrane. Gene Ontology (GO) annotations related to this gene include calcium ion binding and Rab GTPase binding. An important paralog of this gene is RAB11FIP4.
UniProtKB/Swiss-Prot for RAB11FIP3 Gene
-
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an address tag delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Additional gene information for RAB11FIP3 Gene
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB11FIP3 Gene
Genomics for RAB11FIP3 Gene
GeneHancer (GH) Regulatory Elements for RAB11FIP3 Gene
Regulatory Element Products
Genomic Locations for RAB11FIP3 Gene
- chr16:425,592-523,011
- (GRCh38/hg38)
- Size:
- 97,420 bases
- Orientation:
- Plus strand
- chr16:475,619-573,011
- (GRCh37/hg19)
Genomic View for RAB11FIP3 Gene
- Cytogenetic band:
-
- 16p13.3 by Ensembl
- 16p13.3 by Entrez Gene
- 16p13.3 by HGNC


RefSeq DNA sequence for RAB11FIP3 Gene
Proteins for RAB11FIP3 Gene
-
Protein details for RAB11FIP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75154-RFIP3_HUMAN
- Recommended name:
- Rab11 family-interacting protein 3
- Protein Accession:
- O75154
- B0QYI8
- B0QYT8
- B1AHQ0
- B4DEI7
- B4DZR6
- Q4VXV7
- Q7Z5E9
- Q9H155
- Q9H1G0
- Q9NUI0
Protein attributes for RAB11FIP3 Gene
- Size:
- 756 amino acids
- Molecular mass:
- 82440 Da
- Quaternary structure:
-
- Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Interacts with RAB11B, RAB25 and RAB11FIP4. Interacts with ARF6; according to PubMed:16148947, it specifically interacts with ARF6 but not ARF5. Interacts with ARF6; according to PubMed:17030804 but not PubMed:16148947. Interacts with RACGAP1/MgcRacGAP; interaction takes place during late stage of cytokinesis and is required for recruitment to the midbody. Interacts with ASAP1 and EXOC7. Interacts with dynein intermediate chain and dynactin (DCTN1) (PubMed:25035494).
- SequenceCaution:
-
- Sequence=BAA31640.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG57098.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAQ09358.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ09642.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ11003.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for RAB11FIP3 Gene
Protein Expression for RAB11FIP3 Gene
Post-translational modifications for RAB11FIP3 Gene
- Phosphorylated at Ser-102 by CDK1 during metaphase, and dephosphorylated as cells enter telophase.
Other Protein References for RAB11FIP3 Gene
Antibody Products
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-
Santa Cruz Biotechnology (SCBT) Antibodies for RAB11FIP3
Protein Products
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OriGene Purified Proteins for RAB11FIP3
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-
Abcam proteins for RAB11FIP3
Assay Products
No data available for DME Specific Peptides for RAB11FIP3 Gene
Domains & Families for RAB11FIP3 Gene
Gene Families for RAB11FIP3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
Protein Domains for RAB11FIP3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RAB11FIP3 Gene
- GenScript: Design optimal peptide antigens:
-
- RAB11 family interacting protein 3 (Class II) (B0QYT9_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1AHQ1_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1AKD2_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1AKD3_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1B1M9_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75154UniProtKB/Swiss-Prot:
RFIP3_HUMAN :- The RBD-FIP domain mediates the interaction with Rab11 (RAB11A or RAB11B).
- Domain:
-
- The RBD-FIP domain mediates the interaction with Rab11 (RAB11A or RAB11B).
Function for RAB11FIP3 Gene
Molecular function for RAB11FIP3 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an address tag delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Phenotypes From GWAS Catalog for RAB11FIP3 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005509 | calcium ion binding | IEA | -- |
GO:0005515 | protein binding | IPI | 12470645 |
GO:0017137 | Rab GTPase binding | NAS | 11481332 |
GO:0030306 | ADP-ribosylation factor binding | IPI | 16148947 |
GO:0042803 | protein homodimerization activity | IDA | 17030804 |
Phenotypes for RAB11FIP3 Gene
Animal Model Products
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-
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- Overview of 97 available TRAF4 gene related products
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Santa Cruz Biotechnology (SCBT) CRISPR for RAB11FIP3
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miRNA for RAB11FIP3 Gene
- miRTarBase miRNAs that target RAB11FIP3
-
- hsa-mir-484 (MIRT042127)
- hsa-mir-1277-5p (MIRT552065)
- hsa-mir-6516-3p (MIRT552066)
- hsa-mir-190a-3p (MIRT552067)
- hsa-mir-3607-5p (MIRT552068)
- hsa-mir-205-3p (MIRT552069)
- hsa-mir-5011-5p (MIRT552070)
- hsa-mir-5580-3p (MIRT552071)
- hsa-mir-223-5p (MIRT621070)
- hsa-mir-511-3p (MIRT621071)
- hsa-mir-4789-5p (MIRT696141)
- hsa-mir-4672 (MIRT696142)
- hsa-mir-6768-5p (MIRT696143)
miRNA Products
- Search ViGene Biosciences for RAB11FIP3
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- Origene shrna, RNAi, and sirna products in human, mouse, rat for RAB11FIP3
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- genomics-online: shRNA clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
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Recommended
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- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RAB11FIP3
- genomics-online: cdna clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
-
Recommended
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- orf clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
-
Recommended
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RAB11FIP3 Gene
Localization for RAB11FIP3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RAB11FIP3 Gene
- Recycling endosome membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody. Note=In early mitosis remains diffuse and distributed through the cell. The onset of anaphase sequesters these vesicles to the centrosomes at the opposite poles of the cell. During telophase these vesicles move from the centrosomes, to the furrow, and then to the midbody to aid in abscission (PubMed:15158446, PubMed:15601896, PubMed:18511905). Interaction with Rab11 mediates localization to endosomes (PubMed:11495908). Interaction with ARF6 mediates localization to the midbody (PubMed:16148947). {ECO:0000269 PubMed:11495908, ECO:0000269 PubMed:15601896, ECO:0000269 PubMed:16148947, ECO:0000269 PubMed:18511905}.
- Microtubule organizing center (3)
- Vesicles (3)
- Cytokinetic bridge (2)
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005622 | intracellular | IEA | -- |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005768 | endosome | IDA,IEA | 15601896 |
GO:0005813 | centrosome | IDA | 15601896 |
Pathways & Interactions for RAB11FIP3 Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Cargo trafficking to the periciliary membrane | ||
2 | Organelle biogenesis and maintenance |
.56
|
|
3 | Endocytosis | ||
4 | Arf6 downstream pathway |
Pathways by source for RAB11FIP3 Gene
1 BioSystems pathway for RAB11FIP3 Gene
4 Reactome pathways for RAB11FIP3 Gene
1 KEGG pathway for RAB11FIP3 Gene
Interacting Proteins for RAB11FIP3 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000910 | cytokinesis | IMP | 15601896 |
GO:0006810 | transport | IEA | -- |
GO:0007049 | cell cycle | IEA | -- |
GO:0016192 | vesicle-mediated transport | TAS | 16148947 |
GO:0032456 | endocytic recycling | IDA | 17394487 |
No data available for SIGNOR curated interactions for RAB11FIP3 Gene
Transcripts for RAB11FIP3 Gene
mRNA/cDNA for RAB11FIP3 Gene
- (10) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (245) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RAB11FIP3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RAB11FIP3
- genomics-online: gRNA clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
-
Recommended
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-N-His
- pPB-C-His
- pRFP-C-RS
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- Applied Biological Materials CRISPR for RAB11FIP3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RAB11FIP3
- GenScript: Design CRISPR guide RNA sequences for RAB11FIP3
miRNA Products
- Search ViGene Biosciences for RAB11FIP3
Inhibitory RNA Products
- Origene shrna, RNAi, and sirna products in human, mouse, rat for RAB11FIP3
- Browse OriGene Inhibitory RNA Products For RAB11FIP3
- genomics-online: shRNA clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
-
Recommended
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
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- pCMV6-Entry
- pCMV6-XL5
-
ViGene Biosciences ready-to-package AAV shRNAs for RAB11FIP3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RAB11FIP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAB11FIP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RAB11FIP3
- genomics-online: cdna clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
-
Recommended
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- orf clones - Search results for 97 available TRAF4 gene related products
- Overview of 97 available TRAF4 gene related products
-
Recommended
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- Applied Biological Materials Clones for RAB11FIP3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP7: | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP8: | - |
Expression for RAB11FIP3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RAB11FIP3 Gene
NURSA nuclear receptor signaling pathways regulating expression of RAB11FIP3 Gene:
RAB11FIP3SOURCE GeneReport for Unigene cluster for RAB11FIP3 Gene:
Hs.531642Evidence on tissue expression from TISSUES for RAB11FIP3 Gene
- Nervous system(4.6)
- Adrenal gland(2.1)
- Kidney(2)
Primer Products
-
OriGene qPCR primer pairs for RAB11FIP3
-
OriGene qPCR primer pairs and template standards for RAB11FIP3
- genomics-online: primer clones - Search results for 97 available TRAF4 gene related products
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Recommended
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- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
- pRFP-C-RS
- pPB-C-His
- pPB-N-His
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pLenti-U6-sgRNA-PGK-Neo
- pDONR223
- pLenti-C-mGFP
- pLenti-C-Myc-DDK
- pcDNA3.1+C-(K)-DYK
- pCMV6-AC
- pCMV6-Entry
- pCMV6-XL5
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RAB11FIP3 Gene
Orthologs for RAB11FIP3 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | RAB11FIP3 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | RAB11FIP3 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Rab11fip3 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Rab11fip3 33 |
|
||
cow (Bos Taurus) |
Mammalia | RAB11FIP3 33 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | RAB11FIP3 34 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | RAB11FIP3 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | LOC100857269 33 |
|
||
RAB11FIP3 34 |
|
OneToOne | |||
lizard (Anolis carolinensis) |
Reptilia | RAB11FIP3 34 |
|
OneToOne | |
zebrafish (Danio rerio) |
Actinopterygii | rab11fip3 34 |
|
OneToOne | |
fruit fly (Drosophila melanogaster) |
Insecta | nuf 34 |
|
OneToMany | |
worm (Caenorhabditis elegans) |
Secernentea | F55C12.1 34 |
|
OneToMany |
- Species where no ortholog for RAB11FIP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for RAB11FIP3 Gene
(1) SIMAP similar genes for RAB11FIP3 Gene using alignment to 4 proteins:
Variants for RAB11FIP3 Gene
SNP ID | Clin | Chr 16 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000025470 | -- | 438,530(+) | C/T | genic_upstream_transcript_variant, intron_variant | |
rs1000040992 | -- | 438,881(+) | G/A/C | genic_upstream_transcript_variant, intron_variant | |
rs1000059005 | -- | 433,297(+) | C/G | genic_upstream_transcript_variant, intron_variant | |
rs1000088616 | -- | 515,776(+) | G/A/C | genic_downstream_transcript_variant, intron_variant | |
rs1000091388 | -- | 450,874(+) | C/A | genic_upstream_transcript_variant, intron_variant |
Additional Variant Information for RAB11FIP3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RAB11FIP3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAB11FIP3 Gene
Disorders for RAB11FIP3 Gene
Additional Disease Information for RAB11FIP3
No disorders were found for RAB11FIP3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAB11FIP3 Gene
Publications for RAB11FIP3 Gene
- Identification of a novel Rab11/25 binding domain present in Eferin and Rip proteins. (PMID: 11481332) Prekeris R … Scheller RH (The Journal of biological chemistry 2001) 2 3 4 22 58
- Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton. (PMID: 19327867) Jing J … Prekeris R (European journal of cell biology 2009) 3 4 22 58
- Rab11-FIP3 localises to a Rab11-positive pericentrosomal compartment during interphase and to the cleavage furrow during cytokinesis. (PMID: 15158446) Horgan CP … McCaffrey MW (Biochemical and biophysical research communications 2004) 3 4 22 58
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9734811) Ishikawa K … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 2 3 4 58
- Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis. (PMID: 18511905) Simon GC … Prekeris R (The EMBO journal 2008) 3 4 58
Products for RAB11FIP3 Gene
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- Invitrogen Antibodies for RAB11FIP3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for RAB11FIP3
- VectorBuilder custom plasmid, inducible vectors for RAB11FIP3
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RAB11FIP3
- antibodies-online: Search results for 78 available RAB11FIP3 Antibodies ranked by validation data
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- pPB-N-His
- pPB-C-His
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- pCMV6-XL5
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- pCMV6-AC
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
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- Overview of 97 available RAB11FIP3 gene related products
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- pCMV6-XL5
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- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-N-His
- pPB-C-His
- pRFP-C-RS
- pCMV6-XL5
- pCMV6-Entry
- pCMV6-AC
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-N-His
- pPB-C-His
- pRFP-C-RS
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- Overview of 97 available RAB11FIP3 gene related products
- Recommended
- pCMV6-XL5
- pCMV6-Entry
- pCMV6-AC
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-N-His
- pPB-C-His
- pRFP-C-RS
- pCMV6-XL5
- pCMV6-Entry
- pCMV6-AC
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-N-His
- pPB-C-His
- pRFP-C-RS
Sources for RAB11FIP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew