Aliases for RAB11FIP3 Gene
External Ids for RAB11FIP3 Gene
Previous GeneCards Identifiers for RAB11FIP3 Gene
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RAB11FIP3 Gene
RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II)) is a Protein Coding gene. Diseases associated with RAB11FIP3 include medulloblastoma. Among its related pathways are Endocytosis and Arf6 downstream pathway. GO annotations related to this gene include calcium ion binding and Rab GTPase binding.
UniProtKB/Swiss-Prot for RAB11FIP3 Gene
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an address tag delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton.