Aliases for RAB11FIP3 Gene
Aliases for RAB11FIP3 Gene
External Ids for RAB11FIP3 Gene
- HGNC: 17224
- Entrez Gene: 9727
- Ensembl: ENSG00000090565
- OMIM: 608738
- UniProtKB: O75154
Previous GeneCards Identifiers for RAB11FIP3 Gene
- GC16P000416
- GC16P000475
- GC16P000394
Summaries for RAB11FIP3 Gene
-
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RAB11FIP3 Gene
RAB11FIP3 (RAB11 Family Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Cargo trafficking to the periciliary membrane and Arf6 downstream pathway. GO annotations related to this gene include calcium ion binding and Rab GTPase binding. An important paralog of this gene is RAB11FIP4.
UniProtKB/Swiss-Prot for RAB11FIP3 Gene
-
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an address tag delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RAB11FIP3 Gene
Genomics for RAB11FIP3 Gene
Regulatory Elements for RAB11FIP3 Gene
Enhancers for RAB11FIP3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH16G000508 | 1.3 | ENCODE dbSUPER | 4.9 | +83.4 | 83446 | 2.0 | FOXA2 MLX ARID4B DMAP1 ZNF48 TCF12 SLC30A9 GLIS2 PAF1 SP3 | ENSG00000269482 LOC105371038 CCDC154 ENSG00000262528 PIGQ NHLRC4 PRR35 ENSG00000268836 WASH4P FAM234A |
| GH16G000513 | 0.7 | dbSUPER | 4.8 | +88.8 | 88827 | 2.4 | ZNF639 RING1 THRB ZBTB7A ZNF121 ZNF589 GLIS2 ZNF316 ZBTB33 ZNF600 | ENSG00000269482 LOC105371038 CCDC154 ENSG00000262528 PRR35 PIGQ NHLRC4 ENSG00000268836 CAPN15 WASH4P |
| GH16G000423 | 1.1 | ENCODE | 0.7 | -0.1 | -71 | 3.9 | HNRNPUL1 PKNOX1 CREB3L1 ZFP64 SIN3A ARID4B DMAP1 ZNF2 ZBTB7B YY1 | DECR2 NME4 TMEM8A RAB11FIP3 ENSG00000276984 |
| GH16G000428 | 1 | Ensembl ENCODE | 0.7 | +3.5 | 3541 | 1.9 | RFX1 HLF BHLHE40 ZIC2 ATF2 ZNF664 ZNF121 GLIS1 ZSCAN5C ZNF629 | DECR2 NME4 CAPN15 PRR35 PIGQ NHLRC4 RAB11FIP3 GC16M000427 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RAB11FIP3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RAB11FIP3 gene promoter:
Regulatory Element Products
Genomic Location for RAB11FIP3 Gene
- Chromosome:
- 16
- Start:
- 425,592 bp from pter
- End:
- 523,011 bp from pter
- Size:
- 97,420 bases
- Orientation:
- Plus strand
Genomic View for RAB11FIP3 Gene
Genes around RAB11FIP3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.3 by Ensembl
- 16p13.3 by Entrez Gene
- 16p13.3 by HGNC
RAB11FIP3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RAB11FIP3 Gene
Proteins for RAB11FIP3 Gene
-
Protein details for RAB11FIP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O75154-RFIP3_HUMAN
- Recommended name:
- Rab11 family-interacting protein 3
- Protein Accession:
- O75154
- B0QYI8
- B0QYT8
- B1AHQ0
- B4DEI7
- B4DZR6
- Q4VXV7
- Q7Z5E9
- Q9H155
- Q9H1G0
- Q9NUI0
Protein attributes for RAB11FIP3 Gene
- Size:
- 756 amino acids
- Molecular mass:
- 82440 Da
- Quaternary structure:
-
- Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Interacts with RAB11B, RAB25 and RAB11FIP4. Interacts with ARF6; according to PubMed:16148947, it specifically interacts with ARF6 but not ARF5. Interacts with ARF6; according to PubMed:17030804 but not PubMed:16148947. Interacts with RACGAP1/MgcRacGAP; interaction takes place during late stage of cytokinesis and is required for recruitment to the midbody. Interacts with ASAP1 and EXOC7. Interacts with dynein intermediate chain and dynactin (DCTN1) (PubMed:25035494).
- SequenceCaution:
-
- Sequence=BAA31640.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAG57098.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAQ09358.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ09642.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ11003.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for RAB11FIP3 Gene
Protein Expression for RAB11FIP3 Gene
Post-translational modifications for RAB11FIP3 Gene
- Phosphorylated at Ser-102 by CDK1 during metaphase, and dephosphorylated as cells enter telophase.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for RAB11FIP3 Gene
Antibody Products
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- antibodies-online Antibodies for RAB11FIP3: See all 13
- GeneTex RAB11FIP3 antibody for RAB11FIP3
-
Santa Cruz Biotechnology (SCBT) Antibodies for RAB11FIP3
Protein Products
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OriGene Purified Proteins for RAB11FIP3
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- Novus Biologicals proteins for RAB11FIP3
- antibodies-online Proteins for RAB11FIP3: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for RAB11FIP3
No data available for DME Specific Peptides for RAB11FIP3 Gene
Domains & Families for RAB11FIP3 Gene
Gene Families for RAB11FIP3 Gene
Protein Domains for RAB11FIP3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RAB11FIP3 Gene
- GenScript: Design optimal peptide antigens:
-
- RAB11 family interacting protein 3 (Class II) (B0QYT9_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1AHQ1_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1AKD2_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1AKD3_HUMAN)
- RAB11 family interacting protein 3 (Class II) (B1B1M9_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O75154UniProtKB/Swiss-Prot:
RFIP3_HUMAN :- The RBD-FIP domain mediates the interaction with Rab11 (RAB11A or RAB11B).
- Domain:
-
- The RBD-FIP domain mediates the interaction with Rab11 (RAB11A or RAB11B).
Function for RAB11FIP3 Gene
Molecular function for RAB11FIP3 Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an address tag delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005509 | calcium ion binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 12470645 |
| GO:0017137 | Rab GTPase binding | NAS | 11481332 |
| GO:0030306 | ADP-ribosylation factor binding | IPI | 16148947 |
| GO:0042803 | protein homodimerization activity | IDA | 17030804 |
Phenotypes for RAB11FIP3 Gene
Animal Model Products
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for RAB11FIP3 gene
-
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- Search ViGene Biosciences for RAB11FIP3
CRISPR Products
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-
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- GenScript: Design CRISPR guide RNA sequences for RAB11FIP3
miRNA for RAB11FIP3 Gene
- miRTarBase miRNAs that target RAB11FIP3
-
- hsa-mir-484 (MIRT042127)
- hsa-mir-1277-5p (MIRT552065)
- hsa-mir-6516-3p (MIRT552066)
- hsa-mir-190a-3p (MIRT552067)
- hsa-mir-3607-5p (MIRT552068)
- hsa-mir-205-3p (MIRT552069)
- hsa-mir-5011-5p (MIRT552070)
- hsa-mir-5580-3p (MIRT552071)
- hsa-mir-223-5p (MIRT621070)
- hsa-mir-511-3p (MIRT621071)
- hsa-mir-4789-5p (MIRT696141)
- hsa-mir-4672 (MIRT696142)
- hsa-mir-6768-5p (MIRT696143)
miRNA Products
- Search ViGene Biosciences for RAB11FIP3
Inhibitory RNA Products
- Origene siRNA, RNAi, and shRNA products in human, mouse, rat for RAB11FIP3
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Clone Products
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- Addgene plasmids for RAB11FIP3
- VectorBuilder custom plasmid, inducible vectors for RAB11FIP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAB11FIP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RAB11FIP3
-
ViGene Biosciences adenoviral particle packaged cDNA for RAB11FIP3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RAB11FIP3 gene
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ViGene Biosciences ready-to-package AAV shRNAs for RAB11FIP3 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RAB11FIP3 Gene
Localization for RAB11FIP3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RAB11FIP3 Gene
- Recycling endosome membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody. Note=In early mitosis remains diffuse and distributed through the cell. The onset of anaphase sequesters these vesicles to the centrosomes at the opposite poles of the cell. During telophase these vesicles move from the centrosomes, to the furrow, and then to the midbody to aid in abscission (PubMed:15158446, PubMed:15601896, PubMed:18511905). Interaction with Rab11 mediates localization to endosomes (PubMed:11495908). Interaction with ARF6 mediates localization to the midbody (PubMed:16148947). {ECO:0000269 PubMed:11495908, ECO:0000269 PubMed:15601896, ECO:0000269 PubMed:16148947, ECO:0000269 PubMed:18511905}.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 5 |
| endosome | 5 |
| golgi apparatus | 2 |
| plasma membrane | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005768 | endosome | IEA,IDA | 15601896 |
| GO:0005813 | centrosome | IDA | 15601896 |
| GO:0005815 | microtubule organizing center | IDA | -- |
Pathways & Interactions for RAB11FIP3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cargo trafficking to the periciliary membrane | ||
| 2 | Organelle biogenesis and maintenance |
.56
|
|
| 3 | Endocytosis | ||
| 4 | Arf6 downstream pathway | ||
Pathways by source for RAB11FIP3 Gene
1 BioSystems pathway for RAB11FIP3 Gene
4 Reactome pathways for RAB11FIP3 Gene
1 KEGG pathway for RAB11FIP3 Gene
Interacting Proteins for RAB11FIP3 Gene
Selected Interacting proteins:
ENSP00000262305
O75154-RFIP3_HUMAN
for RAB11FIP3 Gene via
STRING
IID
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000910 | cytokinesis | IMP | 15601896 |
| GO:0006810 | transport | IEA | -- |
| GO:0007049 | cell cycle | IEA | -- |
| GO:0016192 | vesicle-mediated transport | TAS | 16148947 |
| GO:0032456 | endocytic recycling | IDA | 17394487 |
No data available for SIGNOR curated interactions for RAB11FIP3 Gene
Transcripts for RAB11FIP3 Gene
mRNA/cDNA for RAB11FIP3 Gene
- (10) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (245) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RAB11FIP3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for RAB11FIP3
-
Santa Cruz Biotechnology (SCBT) CRISPR for RAB11FIP3
- GenScript: Design CRISPR guide RNA sequences for RAB11FIP3
miRNA Products
- Search ViGene Biosciences for RAB11FIP3
Inhibitory RNA Products
- Origene siRNA, RNAi, and shRNA products in human, mouse, rat for RAB11FIP3
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-
ViGene Biosciences ready-to-package AAV shRNAs for RAB11FIP3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for RAB11FIP3
- VectorBuilder custom plasmid, inducible vectors for RAB11FIP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAB11FIP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - |
Expression for RAB11FIP3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (58.3) and Platelet (7.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RAB11FIP3 Gene
NURSA nuclear receptor signaling pathways regulating expression of RAB11FIP3 Gene:
RAB11FIP3SOURCE GeneReport for Unigene cluster for RAB11FIP3 Gene:
Hs.531642Evidence on tissue expression from TISSUES for RAB11FIP3 Gene
- Nervous system(4.6)
- Adrenal gland(2.1)
- Kidney(2)
Primer Products
-
OriGene qPCR primer pairs for RAB11FIP3
-
OriGene qPCR primer pairs and template standards for RAB11FIP3
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RAB11FIP3 Gene
Orthologs for RAB11FIP3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RAB11FIP3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | RAB11FIP3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Rab11fip3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rab11fip3 34 |
|
||
| cow (Bos Taurus) |
Mammalia | RAB11FIP3 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | RAB11FIP3 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | RAB11FIP3 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LOC100857269 34 |
|
||
| RAB11FIP3 35 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | RAB11FIP3 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | rab11fip3 35 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | nuf 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | F55C12.1 35 |
|
OneToMany |
- Species where no ortholog for RAB11FIP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for RAB11FIP3 Gene
(1) SIMAP similar genes for RAB11FIP3 Gene using alignment to 4 proteins:
Variants for RAB11FIP3 Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000025470 | -- | 438,530(+) | CCTCA(C/T)GAGTA | intron-variant | |
| rs1000040992 | -- | 438,881(+) | GACGG(A/C/G)GTTTC | intron-variant | |
| rs1000059005 | -- | 433,297(+) | AAGTA(C/G)TGGGA | intron-variant | |
| rs1000088616 | -- | 515,776(+) | GACAC(C/G)GACCG | intron-variant | |
| rs1000091388 | -- | 450,874(+) | GCTCA(A/C)CTTCC | intron-variant |
Residual Variation Intolerance Score:
41.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.88;
48.52% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RAB11FIP3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RAB11FIP3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAB11FIP3 Gene
Disorders for RAB11FIP3 Gene
Relevant External Links for RAB11FIP3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- RAB11FIP3
No disorders were found for RAB11FIP3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RAB11FIP3 Gene
Publications for RAB11FIP3 Gene
- Identification of a novel Rab11/25 binding domain present in eferin and rip proteins. (PMID: 11481332) Prekeris R. … Scheller R.H. (J. Biol. Chem. 2001) 2 3 4 22 64
- Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton. (PMID: 19327867) Jing J. … Prekeris R. (Eur. J. Cell Biol. 2009) 3 4 22 64
- Rab11-FIP3 localises to a Rab11-positive pericentrosomal compartment during interphase and to the cleavage furrow during cytokinesis. (PMID: 15158446) Horgan C.P. … McCaffrey M.W. (Biochem. Biophys. Res. Commun. 2004) 3 4 22 64
- Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9734811) Ishikawa K. … Ohara O. (DNA Res. 1998) 2 3 4 64
- Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis. (PMID: 18511905) Simon G.C. … Prekeris R. (EMBO J. 2008) 3 4 64
Products for RAB11FIP3 Gene
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- GenScript: Design CRISPR guide RNA sequences for RAB11FIP3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for RAB11FIP3
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for RAB11FIP3
- Novus Biologicals proteins for RAB11FIP3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Invitrogen Antibodies for RAB11FIP3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for RAB11FIP3
- antibodies-online Antibodies for RAB11FIP3: See all 13
- Search antibodies-online for kits
- antibodies-online Proteins for RAB11FIP3: See all 4
- Search antibodies-online for peptides
- GeneTex RAB11FIP3 antibody for RAB11FIP3
- Search GeneTex for Proteins for RAB11FIP3
- ViGene Biosciences adenoviral particle packaged cDNA for RAB11FIP3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for RAB11FIP3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for RAB11FIP3 gene
- Search ViGene Biosciences for RAB11FIP3
- Santa Cruz Biotechnology (SCBT) Antibodies for RAB11FIP3
- Search Santa Cruz Biotechnology (SCBT) for RAB11FIP3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RAB11FIP3
- Horizon Cell Lines for RAB11FIP3
- Cyagen custom Knockout/knockin (KOKI) mouse models for RAB11FIP3
- VectorBuilder custom plasmid, inducible vectors for RAB11FIP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RAB11FIP3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RAB11FIP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer