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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RAB11FIP2 Gene

protein-coding   GIFtS: 61
GCID: GC10M119754

RAB11 Family Interacting Protein 2 (Class I)

  Search for RAB11FIP2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
RAB11 Family Interacting Protein 2 (Class I)1 2     Rab11 Family-Interacting Protein 22
Rab11-FIP22 3     RAB11-FIP2 Long Isoform2
KIAA09413 5     NRip113
nRip112     

External Ids:    HGNC: 291521   Entrez Gene: 228412   Ensembl: ENSG000001075607   OMIM: 6085995   UniProtKB: Q7L8043   

Export aliases for RAB11FIP2 gene to outside databases

Previous GC identifer: GC10M113392


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RAB11FIP2 Gene: 
RAB11FIP2 (RAB11 family interacting protein 2 (class I)) is a protein-coding gene. Among its related super-pathways are Aquaporin-mediated transport and Clathrin-dependent protein traffic. GO annotations related to this gene include protein kinase binding and protein homodimerization activity. An important paralog of this gene is RAB11FIP1.

UniProtKB/Swiss-Prot: RFIP2_HUMAN, Q7L804
Function: A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal
recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane
trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to
phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA). Required in a complex with MYO5B
and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity

Gene Wiki entry for RAB11FIP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RAB11FIP2 gene promoter:
         USF1   AP-2alpha isoform 3   AP-2alpha isoform 2   POU3F2   GATA-1   USF-1   Hand1   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRAB11FIP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for RAB11FIP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB11FIP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.11   Ensembl cytogenetic band:  10q26.11   HGNC cytogenetic band: 10q26.12

RAB11FIP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RAB11FIP2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M119754:  view genomic region     (about GC identifiers)

Start:
119,764,427 bp from pter      End:
119,806,114 bp from pter
Size:
41,688 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RFIP2_HUMAN, Q7L804 (See protein sequence)
Recommended Name: Rab11 family-interacting protein 2  
Size: 512 amino acids; 58279 Da
Subunit: Homooligomerizes in a Rab11-independent manner. Forms a heterooligomeric complex with RAB11FIP4.
Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been
activated by GTP binding. Interacts with NPC1L1
Subcellular location: Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane
protein. Note=Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the
plasma membrane
Sequence caution: Sequence=BAA76785.2; Type=Erroneous initiation;
4 PDB 3D structures from and Proteopedia for RAB11FIP2:
2GZD (3D)        2GZH (3D)        2K6S (3D)        3TSO (3D)    
Secondary accessions: A6NEI4 Q9Y2F0

Explore the universe of human proteins at neXtProt for RAB11FIP2: NX_Q7L804

Explore proteomics data for RAB11FIP2 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylation at Ser-227 by MARK2 regulates epithelial cell polarity
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7L804

  • RAB11FIP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RAB11FIP2 Protein Expression
    REFSEQ proteins: NP_055719.1  
    ENSEMBL proteins: 
     ENSP00000347839   ENSP00000358200  
    Reactome Protein details: Q7L804
    Human Recombinant Protein Products for RAB11FIP2: 
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    Cloud-Clone Corp. Proteins for RAB11FIP2 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005768endosome IDA16905101
    GO:0005886plasma membrane IEA--
    GO:0030659cytoplasmic vesicle membrane TAS--

    RAB11FIP2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR018029 C2_membr_targeting
     IPR008973 C2_Ca/lipid-bd_dom_CaLB
     IPR019018 Rab-bd_FIP-RBD
     IPR000008 C2_Ca-dep

    Graphical View of Domain Structure for InterPro Entry Q7L804

    ProtoNet protein and cluster: Q7L804

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: RFIP2_HUMAN, Q7L804
    Similarity: Contains 1 C2 domain
    Similarity: Contains 1 FIP-RBD domain


    RAB11FIP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RFIP2_HUMAN, Q7L804
    Function: A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal
    recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane
    trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to
    phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA). Required in a complex with MYO5B
    and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12470645
    GO:0019901protein kinase binding IPI16775013
    GO:0042803protein homodimerization activity IPI16905101
         
    RAB11FIP2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RAB11FIP2:
     Increased gamma-H2AX phosphory 

    Animal Models:
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    hsa-miR-411* hsa-miR-379* hsa-miR-429 hsa-miR-513a-5p hsa-miR-15a hsa-miR-1184 hsa-miR-424 hsa-miR-155
    SwitchGear 3'UTR luciferase reporter plasmidRAB11FIP2 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RAB11FIP2 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Regulation of Water Balance by Renal Aquaporins
    Regulation of Water Balance by Renal Aquaporins0.84
    Aquaporin-mediated transport0.84
    2Clathrin-dependent protein traffic
    Transport Clathrin-coated vesicle cycle0.66
    3SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50
    4wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)
    wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)0.38
    5Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3 GeneGo (Thomson Reuters) Pathways for RAB11FIP2
        Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)
    wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)
    Transport Clathrin-coated vesicle cycle

    3        Reactome Pathways for RAB11FIP2
        Transmembrane transport of small molecules
    Aquaporin-mediated transport
    Regulation of Water Balance by Renal Aquaporins


    1         Kegg Pathway  (Kegg details for RAB11FIP2):
        Endocytosis


    RAB11FIP2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAB11FIP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/20 Interacting proteins for RAB11FIP2 (Q7L8041, 2, 3 ENSP000003478394) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAGP619812, 3, ENSP000003063304MINT-50832 I2D: score=4 STRING: ENSP00000306330
    RAB11AP624911, 3, ENSP000002618904EBI-1049676,EBI-745098 I2D: score=3 STRING: ENSP00000261890
    CXCR2P250253, ENSP000003196354I2D: score=3 STRING: ENSP00000319635
    MYO5BQ9ULV03, ENSP000002850394I2D: score=2 STRING: ENSP00000285039
    RAB11BQ159073, ENSP000003335474I2D: score=2 STRING: ENSP00000333547
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006833water transport TAS--
    GO:0015031protein transport IEA--
    GO:0030010establishment of cell polarity IMP16775013
    GO:0035773insulin secretion involved in cellular response to glucose stimulus ISS--
    GO:0045055regulated secretory pathway ISS--

    RAB11FIP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for RAB11FIP2 (RFIP2)

    10/13 HMDB Compounds for RAB11FIP2 (see all 13)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    PA(16:0/16:0)Dipalmitoylphosphatidic acid (see all 25)7091-44-3--
    PA(16:0/18:1(11Z))PA(16:0/18:1n7) (see all 10)----
    PA(16:0/18:1(9Z))PA(16:0/18:1n9) (see all 10)----
    PA(16:0/18:2(9Z,12Z))PA(34:2) (see all 10)----
    PA(16:0e/18:0)2-octadecanoyl-1-hexadecyl-sn-glycero-3-phosphate ;PA(o-16:0/18:0) ----
    PA(18:0/18:2(9Z,12Z))PA(36:2) (see all 10)----
    PA(18:1(11Z)/18:1(11Z))PA(36:2) (see all 10)----
    PA(18:1(11Z)/18:1(9Z))PA(36:2) (see all 10)----
    PA(18:1(9Z)/18:1(11Z))PA(36:2) (see all 10)----

    Search CenterWatch for drugs/clinical trials and news about RAB11FIP2 / RFIP2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RAB11FIP2 gene: 
    NM_014904.2  

    Unigene Cluster for RAB11FIP2:

    RAB11 family interacting protein 2 (class I)
    Hs.173656  [show with all ESTs]
    Unigene Representative Sequence: NM_014904
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000355624(uc001ldj.2 uc009xyz.2) ENST00000476207 ENST00000483413
    ENST00000369199
    miRNA
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    Additional mRNA sequence: 

    AB023158.1 AY037299.1 BC075073.2 BC075074.2 BX647717.1 DQ013303.1 

    5 DOTS entries:

    DT.315059  DT.75155539  DT.121282766  DT.92011077  DT.99998005 

    24/108 AceView cDNA sequences (see all 108):

    AW086181 AW082403 AA261804 BC075073 AI378735 AI126381 AI554523 AV708927 
    AA603053 NM_014904 AI418215 AA353999 AA780510 AL700324 BM975322 AA844093 
    AA491241 BM464387 AA398316 AW241955 BM698885 BC075074 AB023158 AI192727 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RAB11FIP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATCAGAATT
    RAB11FIP2 Expression
    About this image


    See RAB11FIP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RAB11FIP2

    SOURCE GeneReport for Unigene cluster: Hs.173656
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB11FIP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RAB11FIP2 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rab11fip21 , 5 RAB11 family interacting protein 2 (class I)1, 5 89.53(n)1
    93.48(a)1
      19 (56.28 cM)5
    749981  NM_001033172.31  NP_001028344.21 
     599028845 
    chicken
    (Gallus gallus)
    Aves RAB11FIP21 RAB11 family interacting protein 2 (class I) 80.07(n)
    81.96(a)
      423924  XM_421784.3  XP_421784.1 
    lizard
    (Anolis carolinensis)
    Reptilia RAB11FIP26
    Uncharacterized protein
    78(a)
    1 ↔ 1
    GL343206.1(649407-679804)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.339372 Xenopus laevis transcribed sequence with moderate similarity more 72.56(n)    CD255310.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.165412 Transcribed sequence with moderate similarity to protein more 71.57(n)    BI709917.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Rip116
    Rab11 interacting protein
    13(a)
    1 → many
    X(18529675-18541596)


    ENSEMBL Gene Tree for RAB11FIP2 (if available)
    TreeFam Gene Tree for RAB11FIP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RAB11FIP2 gene
    RAB11FIP12  RAB11FIP52  
    2 SIMAP similar genes for RAB11FIP2 using alignment to 2 protein entries:     RFIP2_HUMAN (see all proteins):
    GAF1    RAB11FIP1

    RAB11FIP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/722 SNPs in RAB11FIP2 are shown (see all 722)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1415007601,2
    C,Funtested1119774577(+) TTACCA/G/TGGATT 2 Q P mis12NA EU 5861
    rs1871312691,2
    --119764071(+) TGTTGC/TGAGAA 1 -- int10--------
    rs1407394711,2
    C--119764136(+) TACTC-/AAAATA 1 -- int10--------
    rs1911642561,2
    --119764157(+) TAAATC/TGTAAG 1 -- int10--------
    rs1815050831,2
    --119764335(+) AGAGGC/TATCCT 1 -- int10--------
    rs1858843511,2
    --119764367(+) GAGGAC/TTCATA 1 -- int10--------
    rs1899000311,2
    --119764370(+) GACTCA/GTATAT 1 -- int10--------
    rs170972391,2
    C,F,H--119764395(+) AACACC/TGCTGT 1 -- int117Minor allele frequency- T:0.02NA NS EA WA 2110
    rs1832738361,2
    --119764396(+) ACACCA/GCTGTA 1 -- int10--------
    rs1444704841,2
    --119764606(+) GATAAA/GTGTTA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for RAB11FIP2 (119764427 - 119806114 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for RAB11FIP2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv7567CNV Insertion18451855
    nsv528184CNV Loss19592680
    nsv516870CNV Loss19592680
    nsv7566CNV Loss18451855
    nsv825580CNV Gain20364138
    nsv832005CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    RAB11FIP2 for disorders           About MalaCards
    OMIM gene information: 608599    OMIM disorders: --


    RAB11FIP2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RAB11FIP2
    Human Genome Epidemiology (HuGE) Navigator: RAB11FIP2 (1 document)

    Export disorders for RAB11FIP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RAB11FIP2 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with RAB11FIP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Rab11-FIP2 functions in transferrin recycling and associates with endosomal membranes via its COOH-terminal domain. (PubMed id 11994279)1, 2, 3 Lindsay A.J. and McCaffrey M.W. (2002)
    2. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
    3. Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface. (PubMed id 19542231)1, 2, 9 Chu B.B....Song B.L. (2009)
    4. Crystal structure of rab11 in complex with rab11 family interacting protein 2. (PubMed id 16905101)1, 2, 9 Jagoe W.N....Khan A.R. (2006)
    5. The C2 domains of the class I Rab11 family of interacting proteins target recycling vesicles to the plasma membrane. (PubMed id 15304524)1, 2, 9 Lindsay A.J. and McCaffrey M.W. (2004)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    7. MARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting protein 2 is necessary for the timely establishment of polarity in Madin-Darby canine kidney cells. (PubMed id 16775013)1, 2 Ducharme N.A....Goldenring J.R. (2006)
    8. Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins. (PubMed id 15173169)1, 2 Junutula J.R....Prekeris R. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. The novel Rab11-FIP/Rip/RCP family of proteins displays extensive homo- and hetero-interacting abilities. (PubMed id 11944901)1, 2 Wallace D.M.... McCaffrey M.W. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22841 HGNC: 29152 AceView: RAB11FIP2 Ensembl:ENSG00000107560 euGenes: HUgn22841
    ECgene: RAB11FIP2 Kegg: 22841 H-InvDB: RAB11FIP2

    (According to HUGE)
    About This Section
    HUGE: KIAA0941

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RAB11FIP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RAB11FIP2 gene:
    Search GeneIP for patents involving RAB11FIP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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