Aliases for RAB11FIP2 Gene
External Ids for RAB11FIP2 Gene
Previous GeneCards Identifiers for RAB11FIP2 Gene
GeneCards Summary for RAB11FIP2 Gene
RAB11FIP2 (RAB11 Family Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF). GO annotations related to this gene include protein homodimerization activity and Rab GTPase binding. An important paralog of this gene is RAB11FIP5.
UniProtKB/Swiss-Prot for RAB11FIP2 Gene
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.