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Aliases & Descriptions for RAB11B
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| H-YPT3 1, 2 | | MGC133246 2 | | YPT3 3 |
| | | Descriptions |
|---|
| GTP-binding protein YPT3 3 | | RAB11B, member RAS oncogene family 2 | | RAB11B, member of RAS oncogene family 2 |
|
| | Search outside databases for aliases for RAB11B genePrevious GC identifers: GC19P008396 GC19P008546 GC19P008350 |
Summaries for RAB11B(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: RB11B_HUMAN, Q15907Function: Possesses GTPase activityGene Wiki entry for RAB11B |
Genomic Location for RAB11B
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Transcription factor binding sites upstream to the RAB11B gene 
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2RAB11B Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P008361:
(about GC identifiers)
Start:
|
8,361,296 bp from pter |
End:
|
8,375,318 bp from pter |
Size:
|
14,023 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000019.8 NT_077812.2
| Proteins for RAB11B
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: RB11B_HUMAN, Q15907 (See
protein sequence)Recommended Name: Ras-related protein Rab-11B Size: 218 amino acids; 24489 Da
Subunit: Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
PDB structure from and Proteopedia :2F9L (3D)
 2F9M (3D)
 
Secondary accessions: B2R7I4 Q2YDT2 Q8NI07Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_004209.2
ENSEMBL proteins: ENSP00000333547
Human Recombinant Proteins Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
2 Gene Ontology (GO) cellular component terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016023 | cytoplasmic membrane-bounded vesicle |
IEA | -- | About this table
Antibodies for RAB11B: Assays for RAB11B: | Protein
Domains/ Families for RAB11B(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q15907
ProtoNet protein and cluster: Q15907 1 Blocks protein family: IPB001806 Transforming protein P21 RAS signature
UniProtKB/Swiss-Prot: RB11B_HUMAN, Q15907Similarity: Belongs to the small GTPase superfamily. Rab family | Gene Function for RAB11B
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004218
Applied Biosystems Silencer® siRNAs for RAB11B
Sigma-Aldrich siRNA for RAB11B  Sigma-Aldrich shRNA for RAB11B  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004218                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_004218                                  untagged cDNA clone in CMV expression vector: NM_004218 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_004218
UniProtKB/Swiss-Prot: RB11B_HUMAN, Q15907Function: Possesses GTPase activity3 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions for RAB11B
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| 2 Sigma-Aldrich "Your Favorite Gene" Pathways for RAB11B (Your Favorite Gene powered by Ingenuity) 
Gene Network CentralTM Interacting Genes and Proteins Network for RAB11B 
1 Interacting protein for RAB11B (ENSP000003335473) via UniProtKB, MINT, and/or STRINGAbout this table
2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
IEA | -- | | GO:0015031 | protein transport |
IEA | -- | About this table
|
Drugs & Compounds for RAB11B(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for RAB11B
|
Transcripts for RAB11B(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004218
Sigma-Aldrich siRNA for RAB11B  Sigma-Aldrich shRNA for RAB11B  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_004218 REFSEQ mRNAs for RAB11B gene: NM_004218.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_004218               OriGene GFP tagged cDNA clone in CMV expression vector: NM_004218                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_004218                                  untagged cDNA clone in CMV expression vector: NM_004218  Additional cDNA sequence: AF498947.1 AK225036.1 AK225642.1 AK297498.1 AK310573.1 AK312994.1 BC110081.1 BT019535.1 BT019536.1 CR536494.1 CR541691.1 CR590650.1 CR592057.1 CR592281.1 CR593189.1 CR593323.1 CR593439.1 CR594452.1 CR596517.1 CR597131.1 CR600179.1 CR600800.1 CR605393.1 CR606224.1 CR606883.1 CR609776.1 CR613165.1 CR613277.1 CR615157.1 CR618647.1 CR618667.1 CR620665.1 CR621845.1 CR624386.1 CR625102.1 CR626143.1 CR626645.1 D38516.1 EF560724.1 X79780.1 24/27 DOTS entries (see all 27
): DT.100654291 DT.91777995 DT.100643817 DT.432925 DT.121477825 DT.91777990 DT.95176044 DT.100654296 DT.100746160 DT.91777997 DT.100654281 DT.121477712 DT.100759077 DT.75101305 DT.100654282 DT.75146769 DT.121477716 DT.121477754 DT.121477755 DT.121477794 DT.91777989 DT.92056983 DT.95176029 DT.95176047 24/632 AceView cDNA sequences (see all 632
):BU754446 BU728778 AA687467 CR594452 BU735141 BM543168 CR613277 BM801322 BQ682487 AW160512 CR592281 BI488603 BU855688 BE263527 BG151535 BQ881881 CA430893 AI378449 BE732553 AI718910 BU508476 BU735248 BP362865 CR609776
highest scoring ESTs for RAB11B:X79780 AF498947 AL525058 AL551873 AW651764 AW732313 BE254888 BE256796 BE263748 BE535311 Unigene Cluster for RAB11B: RAB11B, member RAS oncogene family Hs.626404 [show with all ESTs]Unigene Representative Sequence: NM_004218
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for RAB11B (see all 6
)
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |
| SP3: | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for RAB11B
1 Ensembl transcript including schematic representation: ENST00000328024
|
Expression for RAB11B
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| RAB11B expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for RAB11B
1 / 2 / 3 8 probe-sets matching RAB11B gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: AAACTCGGGT
SOURCE GeneReport for Unigene cluster: Hs.626404
Expression variation in blood from EXPOLDB for RAB11B |
Orthologs for RAB11B
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for RAB11B gene from 5/21 species (see all 21
)
About this table Species with no ortholog for RAB11B
ENSEMBL Gene Tree for RAB11B | Paralogs for RAB11B(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for RAB11B gene
- RAB352 RAB252 RAB11A2
|
SNPs/Variants for RAB11B(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for RAB11B (up to first 250kb)
|
Disorders & Mutations for RAB11B
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 604198
|
Medical News for RAB11B(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for RAB11B (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/13 PubMed articles for RAB11B gene (see all 13
): |
Search for RAB11B
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing RAB11B
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing RAB11B
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAB11B(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for RAB11B(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for RAB11B:

 | |
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| Antibodies & Assays for RAB11B  |
| | | | Search Tocris compounds for RAB11B |
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Incremental update: 13 Oct 2009
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