RAB11A Gene
protein-coding GIFtS: 68
GCID: GC15P066018
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|
RAB11A, member RAS oncogene family
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Aliases
for RAB11A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RAB11A, Member RAS Oncogene Family1 2 | | Ras-Related Protein Rab-11A2 | | YL81 2 3 | | RAB113 | | RAB 11A, Member Oncogene Family2 | | Rab-113 | | Rab-113 | | |
Export aliases for RAB11A gene to outside databasesPrevious GC identifers: GC15P061897 GC15P059260 GC15P063740 GC15P063877 GC15P063948 GC15P066161 GC15P042986 |
Summaries
for RAB11A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RAB11A:
The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with bothconstitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variantsencoding different isoforms have been found for this gene. (provided by RefSeq, May 2011)
UniProtKB/Swiss-Prot: RB11A_HUMAN, P62491Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation oftransport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an activeGTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible forvesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulatorof membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization.Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXLto the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5Bparticipates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Requiredin a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sortingand basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT(receptor of Fc region of monomeric Ig G) to basolateral membranes. May also play a role in melanosome transport andrelease from melanocytes
Gene Wiki entry for RAB11A
|
Genomic Views
for RAB11A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RAB11A gene promoter:
SRF Sox5 SRF (504 AA) Lmo2 C/EBPalpha Roaz GATA-1 S8 NRF-2 En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RAB11A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB11A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q22.31 Ensembl cytogenetic band: 15q22.31 HGNC cytogenetic band: 15q22.31RAB11A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15P066018: view genomic region
(about GC identifiers)
Start:
|
66,018,392 bp from pter |
End:
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66,184,329 bp from pter |
Size:
|
165,938 bases |
Orientation:
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plus strand |
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Proteins
for RAB11A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RB11A_HUMAN, P62491 (See
protein sequence)Recommended Name: Ras-related protein Rab-11A precursor Size: 216 amino acids; 24394 Da
Subunit: Interacts with RIP11 and STXBP6. Interacts with SGSM1, SGSM2 and SGSM3 (By similarity). Interacts with EXOC6in a GTP-dependent manner (By similarity). Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 (via its C-terminus) andRAB11FIP4. Interacts with EVI5; EVI5 and RAB11FIP3 may be mutually exclusive and compete for binding RAB11A. Interactswith VIPAS39. Interacts with MYO5B. Found in a complex with MYO5B and CFTR. Interacts with NPC1L1. Interacts(GDP-bound form) with ZFYVE27. Interacts with BIRC6/bruce. May interact with TBC1D14
Subcellular location: Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membraneprotein. Cleavage furrow. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor;Cytoplasmic side (By similarity). Note=Translocates with RAB11FIP2 from the vesicles of the endocytic recyclingcompartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5,OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface andlumenogenesis. Recruited to phagosomes containing S.aureus or M.tuberculosis
6/8 PDB 3D structures from  and Proteopedia  for RAB11A (see all 8):1OIV (3D)
1OIW (3D)
1OIX (3D)
1YZK (3D)
2D7C (3D)
2GZD (3D)
Secondary accessions: B2R4B6 P24410 Q5TZN9 Q9JLX1Explore the universe of human proteins at neXtProt for RAB11A: NX_P62491
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62491
RAB11A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001193765.1 NP_004654.1
ENSEMBL proteins: ENSP00000455567 ENSP00000261890 ENSP00000454381 ENSP00000456638 ENSP00000456420 ENSP00000454673 ENSP00000405767 Reactome Protein details: P62491
Human Recombinant Protein Products:
Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11): About this table
RAB11A for ontologies About GeneDecksing
RAB11A Antibody Products:
Assay Products for RAB11A: |
Protein
Domains /
Families
for RAB11A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RAB11A for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62491ProtoNet protein and cluster: P62491 3 Blocks protein families: IPB002041 GTP-binding nuclear protein Ran IPB003577 Ras small GTPase IPB003578 Ras small GTPase
UniProtKB/Swiss-Prot: RB11A_HUMAN, P62491Similarity: Belongs to the small GTPase superfamily. Rab family |
Function
for RAB11A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RB11A_HUMAN, P62491Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation oftransport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an activeGTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible forvesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulatorof membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization.Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXLto the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5Bparticipates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Requiredin a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sortingand basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT(receptor of Fc region of monomeric Ig G) to basolateral membranes. May also play a role in melanosome transport andrelease from melanocytes Genatlas biochemistry entry for RAB11A:RAS related GTP-binding protein,branch rab,member 11,widely expressed with two transcripts small and large,putativelyinvolved in secretory pathway
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAB11A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB11A |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RAB11A for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for RAB11A:
|
Pathways & Interactions
for RAB11A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clathrin-dependent protein traffic | | | 2 | Regulation of Water Balance by Renal Aquaporins | | | 3 | Cytoskeletal Signaling | | | 4 | Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF) | | | 5 | wtCFTR and deltaF508 traffic / Membrane expression (norm and CF) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for RAB11A
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for RAB11A
1 
Cell Signaling Technology (CST) Pathway for RAB11A
4  GeneGo (Thomson Reuters) Pathways for RAB11A
3  BioSystems Pathways for RAB11A
4 
Reactome Pathways for RAB11A
4 
Kegg Pathways (Kegg details for RAB11A):
RAB11A for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RAB11A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/45 Interacting proteins for RAB11A (P624911, 2, 3 ENSP000002618904) via UniProtKB, MINT, STRING, and/or I2D (see all 45)About this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table
RAB11A for ontologies About GeneDecksing
|
Drugs & Compounds
for RAB11A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RAB11A for compounds About GeneDecksing
 Browse Tocris compounds for RAB11A
2 DrugBank Compounds for RAB11A About this table
3 Novoseek chemical compound relationships for RAB11A gene About this table
Search CenterWatch for drugs/clinical trials and news about RAB11A / RB11A
|
Transcripts
for RAB11A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RAB11A gene (2 alternative transcripts): NM_001206836.1 NM_004663.4 Unigene Cluster for RAB11A: RAB11A, member RAS oncogene family Hs.321541 [show with all ESTs]Unigene Representative Sequence: NM_00466310 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000569304 ENST00000563580 ENST00000568850 ENST00000564910 ENST00000261890(uc002apk.3 uc010ujk.2)
ENST00000566233 ENST00000565075 ENST00000569896 ENST00000567671 ENST00000435304
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAB11A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAB11A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RAB11A (NM_004663) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RAB11A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB11A |
Additional cDNA sequence: AF000231.1 AF498946.1 AK297549.1 AK298961.1 AK300008.1 AK311770.1 BC013348.2 BC047114.1 BT020151.1 BT020154.1 CR407669.1 CR536493.1 X53143.1 X56740.1 19 DOTS entries: DT.100827594 DT.449969 DT.97795542 DT.100827606 DT.100827603 DT.92457074 DT.97859949 DT.453180 DT.121029061 DT.95257491 DT.121028925 DT.121028951 DT.121028994 DT.121029068 DT.100827601 DT.101964760 DT.121028932 DT.121028969 DT.95204929 2 AceView cDNA sequences: AK054930 AL138360
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for RAB11A About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for RAB11A
|
Expression
for RAB11A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RAB11A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTATGGCTTC
About this image
See RAB11A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RAB11A
SOURCE GeneReport for Unigene cluster: Hs.321541
SABiosciences Custom PCR Arrays for RAB11A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAB11A
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB11A |
Orthologs
for RAB11A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RAB11A gene from 9/36 species (see all 36) About this table
ENSEMBL Gene Tree for RAB11A (if available)
TreeFam Gene Tree for RAB11A (if available) |
Paralogs
for RAB11A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RAB11A gene
- RAB39A2 RAB252 RAB2A2 RAB142 RAB4B2 RAB39B2 RAB11B2 RAB422
- RAB4A2 RAB2B2
18/103 SIMAP similar genes for RAB11A using alignment to 7 protein entries: RB11A_HUMAN (see all proteins)
(see all similar genes):RAB11B RAB25 RAB19 RAB43 RAB4B DKFZp686J06205
RAB13 RAB30 RAB8B rab1b RAB5C RAB5B
DKFZp686J07132 RAB7A RAB8A RAB2B RAB3B RAB15
RAB11A for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for RAB11A
PGOHUM00000258503 PGOHUM00000239504
|
Genomic Variants
for RAB11A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RAB11A (66018392 - 66184329 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RAB11A
1 CNV: 3964 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAB11A |
|
Disorders
/ Diseases
for RAB11A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RAB11A for disorders About GeneDecksing
OMIM gene information: 605570
OMIM disorders: --
19  diseases for RAB11A: About MalaCardscharcot-marie-tooth disease charcot-marie-tooth disease type 4 barrett's esophagus tooth disease
esophagus squamous cell carcinoma squamous cell carcinoma arthrogryposis cystic fibrosis
cholestasis fibrosis influenza breast cancer
carcinoma cholesterol neuroblastoma schizophrenia
pancreatitis malaria neuronitis
1 disease from the University of Copenhagen DISEASES database for RAB11A:Esophagus squamous cell carcinoma 3 Novoseek disease relationships for RAB11A gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| barrett esophagus |
24 |
1 |
9389793 (1) |
| dysplasia |
0 |
7 |
9389793 (4), 10212817 (2) |
| adenocarcinoma |
0 |
1 |
9389793 (1) |
Human Genome Epidemiology (HuGE) Navigator: RAB11A (1 document)
Export disorders for RAB11A gene to outside databases
|
Publications
for RAB11A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RAB11A gene, integrated from 9 sources (see all 179):
(articles sorted by number of sources associating them with RAB11A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human rab11a: transcription, chromosome mapping and effect on the expression levels of host GTP-binding proteins. (PubMed id 9662449)1, 2, 3 Gromov P.S....Madsen P. (1998)
- Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. (PubMed id 1704119)1, 2, 3 Drivas G.T.... Rush M.G. (1991)
- Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins. (PubMed id 15173169)1, 2, 9 Junutula J.R....Prekeris R. (2004)
- Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1. (PubMed id 17030804)1, 2, 9 Shiba T....Wakatsuki S. (2006)
- Rab coupling protein (RCP), a novel Rab4 and Rab11 effector protein. (PubMed id 11786538)1, 2, 9 Lindsay A.J.... McCaffrey M.W. (2002)
- Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface. (PubMed id 19542231)1, 2, 9 Chu B.B....Song B.L. (2009)
- Myosin Vb is required for trafficking of the cystic f ibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells. (PubMed id 17462998)1, 2, 9 Swiatecka-Urban A....Stanton B.A. (2007)
- The RCP-Rab11 complex regulates endocytic protein sorting. (PubMed id 15181150)1, 2, 9 Peden A.A....Prekeris R. (2004)
- Crystallographic evidence for substrate-assisted GTP hydrolysis by a small GTP binding protein. (PubMed id 15837192)1, 2, 9 Pasqualato S. and Cherfils J. (2005)
- TBC1D14 regulates autophagosome formation via Rab11- a nd ULK1-positive recycling endosomes. (PubMed id 22613832)1, 2 Longatti A....Tooze S.A. (2012)
|
External Searches for RAB11A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RAB11A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RAB11A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RAB11A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for RAB11A gene:
Search GeneIP for patents involving RAB11A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RAB11A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for RAB11A | | OriGene shRNA RFP for RAB11A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RAB11A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RAB11A | | | OriGene Protein Over-expression Lysate for RAB11A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RAB11A | | OriGene 3'-UTR Clone for RAB11A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RAB11A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RAB11A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RAB11A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RAB11A | | OriGene Custom Protein Services for RAB11A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RAB11A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RAB11A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RAB11A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RAB11A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RAB11A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RAB11A |
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| | Antibodies & Assays for RAB11A |
| | | | Search Tocris compounds for RAB11A |
| |  |  |  |  | | | | | | Recombinant Protein for RAB11A |
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 | | | RAB11A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RAB11A |
|  |  |  | | | | ThermoFisher Antibodies for RAB11A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RAB11A |
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